𝕏

Task 55754646

Name HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pueyo_APDR-conf_272_1
Workunit 26475488
Created 2 Jul 2024, 13:59:15 UTC
Sent 2 Jul 2024, 19:51:43 UTC
Report deadline 6 Jul 2024, 5:27:43 UTC
Received 4 Jul 2024, 18:37:09 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 238434
Run time 1 hours 26 min 48 sec
CPU time 54 min 5 sec
Validate state Initial
Credit 0.00
Device peak FLOPS 6.36 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.19 MB
Peak swap size 5.30 MB
Peak disk usage 0.26 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pueyo_APDR-conf_272.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pueyo_APDR-conf_272_1_r1829632471_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pueyo_APDR-conf_272_1_r1829632471_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 106.437609
     * GNaL_b in INaL: 0.005968
     * Gto_b in Ito: 0.086686
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031652
     * GKs_b in IKs: 0.001900
     * GK1_b in IK1: 0.167118
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 71.300723
     * GKb_b in IKb: 0.003790
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037152
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12283859, states[0] = -95.100371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 27952559, states[0] = -95.130318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 44222782, states[0] = -94.962437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59884142, states[0] = -95.081042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 76200698, states[0] = -94.903015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 92938094, states[0] = -95.083374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109425500, states[0] = -95.078002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 126214588, states[0] = -94.919859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 142539014, states[0] = 15.800218, states[40]= 0.005266
Saving checkpoint... 
Iteration: 158498077, states[0] = -95.086665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 175157119, states[0] = -83.669201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 191783186, states[0] = -95.005865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208053513, states[0] = 10.443655, states[40]= 0.004899
Saving checkpoint... 
Iteration: 224557075, states[0] = 9.029254, states[40]= 0.004856
Saving checkpoint... 
Iteration: 240288801, states[0] = -95.010408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 256794131, states[0] = -95.014728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 273178275, states[0] = -94.819927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 289735426, states[0] = -94.950580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 305795161, states[0] = -95.015472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321873621, states[0] = -95.058547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 337676799, states[0] = -94.801177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 353343004, states[0] = -95.045466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 368506633, states[0] = 25.180812, states[40]= 0.113722
Saving checkpoint... 
Iteration: 385138863, states[0] = -57.399682, states[40]= 0.000008
Saving checkpoint... 
Iteration: 396858794, states[0] = -95.052645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 412802855, states[0] = -95.021233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 429156735, states[0] = -82.899423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 445495053, states[0] = -95.085139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462956525, states[0] = -95.079643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 480865534, states[0] = -95.055352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497640254, states[0] = -58.996813, states[40]= 0.000006
Saving checkpoint... 
Iteration: 514767340, states[0] = -94.989962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 530711437, states[0] = -94.911322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 541810368, states[0] = -95.026437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 549467295, states[0] = -95.081327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 560582024, states[0] = -3.408870, states[40]= 0.003677
Saving checkpoint... 
Iteration: 576060136, states[0] = 7.775144, states[40]= 0.004814
Saving checkpoint... 
Iteration: 592277775, states[0] = -95.000280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609311390, states[0] = -95.027084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 625535185, states[0] = 17.117890, states[40]= 0.005510
Saving checkpoint... 
Iteration: 641150557, states[0] = -72.404925, states[40]= 0.000001
Saving checkpoint... 
Iteration: 657629938, states[0] = -47.579367, states[40]= 0.000041
Saving checkpoint... 
Iteration: 673737296, states[0] = -94.953004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690207908, states[0] = -94.904741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706528896, states[0] = 19.045351, states[40]= 0.006229
Saving checkpoint... 
Iteration: 722541216, states[0] = 15.049227, states[40]= 0.005166
Saving checkpoint... 
Iteration: 734114441, states[0] = -32.102497, states[40]= 0.000372
Saving checkpoint... 
Iteration: 750025046, states[0] = 20.064416, states[40]= 0.007088
Saving checkpoint... 
Iteration: 766303233, states[0] = -95.021287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782172216, states[0] = -94.652044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 797664649, states[0] = -92.892289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812734742, states[0] = -94.949235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829172761, states[0] = -94.682174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 846298552, states[0] = -95.017750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 863367062, states[0] = -95.055715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879541175, states[0] = 15.063863, states[40]= 0.005167
Saving checkpoint... 
Iteration: 896356216, states[0] = -95.051228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913096929, states[0] = -15.641000, states[40]= 0.001372
Saving checkpoint... 
Iteration: 929407146, states[0] = -95.068724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 944706488, states[0] = -94.901922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 961385267, states[0] = -95.062191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977749208, states[0] = -94.968792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 993896309, states[0] = -95.065624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1009729231, states[0] = -94.940842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025687368, states[0] = -94.862443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042294484, states[0] = -95.014462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058434792, states[0] = -95.075186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1074682373, states[0] = -94.846606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090955910, states[0] = -95.079146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1107150601, states[0] = -72.471447, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1123344022, states[0] = -95.045480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1138984372, states[0] = -95.083379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1150449195, states[0] = -95.077927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1166549614, states[0] = 11.951116, states[40]= 0.004951
Saving checkpoint... 
Iteration: 1182823009, states[0] = -95.034085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1198163089, states[0] = -91.809631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1214411466, states[0] = -95.069682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230558838, states[0] = 8.313404, states[40]= 0.004833
Saving checkpoint... 
Iteration: 1246587471, states[0] = -7.368649, states[40]= 0.002870
Saving checkpoint... 
Iteration: 1262846781, states[0] = -95.046720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1274211944, states[0] = -94.911770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1289480243, states[0] = -95.082736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306071126, states[0] = 2.806351, states[40]= 0.004523
Saving checkpoint... 
Iteration: 1317190176, states[0] = -94.868859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333778410, states[0] = -95.000411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1349335548, states[0] = -95.041036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1365310812, states[0] = -95.026222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1380841746, states[0] = -95.044198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397174227, states[0] = -94.741864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1408362444, states[0] = -95.053529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425092246, states[0] = -11.377930, states[40]= 0.002046
Saving checkpoint... 
Iteration: 1442059950, states[0] = 7.852934, states[40]= 0.004817
Saving checkpoint... 
Iteration: 1456796323, states[0] = -95.015650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1472850078, states[0] = -95.048128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1487172238, states[0] = -94.652854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1501875001, states[0] = -7.013437, states[40]= 0.003202
Saving checkpoint... 
Iteration: 1516415876, states[0] = -95.232892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1531681137, states[0] = -95.182519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1546492306, states[0] = -95.336094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1561406252, states[0] = -95.247792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1576553792, states[0] = 5.684324, states[40]= 0.005391
Saving checkpoint... 
Iteration: 1591385125, states[0] = -95.213767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1606106713, states[0] = -95.256477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1620813229, states[0] = -95.268032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1635670895, states[0] = -6.269984, states[40]= 0.003510
Saving checkpoint... 
Iteration: 1649756051, states[0] = 4.272321, states[40]= 0.005274
Saving checkpoint... 
Iteration: 1665206887, states[0] = -95.258784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1680222280, states[0] = -95.282813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1694934737, states[0] = -95.299432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1710505800, states[0] = -95.257168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1725872013, states[0] = -95.337322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1740863171, states[0] = -95.329698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1755995325, states[0] = -32.088985, states[40]= 0.000366
Saving checkpoint... 
Iteration: 1770775264, states[0] = -95.195346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1785841102, states[0] = -95.307090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1799784300, states[0] = -20.116994, states[40]= 0.001033
Saving checkpoint... 
Iteration: 1815268906, states[0] = -95.032295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1829685474, states[0] = -94.885863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1843884025, states[0] = -95.079837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1858673107, states[0] = -94.746147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1873361261, states[0] = -95.060474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1888418756, states[0] = -95.075987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1902909617, states[0] = -95.071951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1918130511, states[0] = -48.348921, states[40]= 0.000036
Saving checkpoint... 
Iteration: 1933618634, states[0] = -36.207797, states[40]= 0.000221
Saving checkpoint... 
Iteration: 1949182608, states[0] = -94.847940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1963453270, states[0] = -95.078634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1978347734, states[0] = -95.047020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1992817713, states[0] = -95.030504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2007261848, states[0] = -94.983205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2021985141, states[0] = -95.082972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2036854475, states[0] = -95.049764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2052363229, states[0] = -95.053432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2067017885, states[0] = 21.549004, states[40]= 0.012178
Saving checkpoint... 
Iteration: 2082222097, states[0] = -94.928752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2097265731, states[0] = -94.987227, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.960509
 - CaMKt in component CaMK (millimolar): 0.006945
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.541939
 - nass in component intracellular_ions (millimolar): 6.541999
 - ki in component intracellular_ions (millimolar): 145.436673
 - kss in component intracellular_ions (millimolar): 145.436654
 - cansr in component intracellular_ions (millimolar): 1.307720
 - cajsr in component intracellular_ions (millimolar): 1.269622
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003597
 - hf in component INa (dimensionless): 0.881015
 - hs in component INa (dimensionless): 0.881010
 - j in component INa (dimensionless): 0.880983
 - hsp in component INa (dimensionless): 0.727745
 - jp in component INa (dimensionless): 0.880964
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.711292
 - hLp in component INaL (dimensionless): 0.453243
 - a in component Ito (dimensionless): 0.000621
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.620598
 - ap in component Ito (dimensionless): 0.000316
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.695422
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934677
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999883
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001585
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.331768
 - xs1 in component IKs (dimensionless): 0.243500
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997322
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
21:45:51 (7060): called boinc_finish(0)

</stderr_txt>
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