𝕏

Task 55754501

Name HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_MID_3000-conf_772_0
Workunit 26475416
Created 2 Jul 2024, 13:59:10 UTC
Sent 2 Jul 2024, 19:58:49 UTC
Report deadline 5 Jul 2024, 19:58:49 UTC
Received 3 Jul 2024, 7:10:53 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 230398
Run time 2 hours 5 min 15 sec
CPU time 2 hours 4 min 14 sec
Validate state Valid
Credit 41.69
Device peak FLOPS 3.87 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.72 MB
Peak swap size 4.10 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.24.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_MID_3000-conf_772.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_MID_3000-conf_772_0_r2063394168_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_MID_3000-conf_772_0_r2063394168_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.924420
     * GNaL_b in INaL: 0.006024
     * Gto_b in Ito: 0.082259
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031901
     * GKs_b in IKs: 0.001952
     * GK1_b in IK1: 0.163941
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 70.284513
     * GKb_b in IKb: 0.003782
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030469
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12266747, states[0] = -42.386801, states[40]= 0.001455
Saving checkpoint... 
Iteration: 24389338, states[0] = -94.001350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35997365, states[0] = -94.235666, states[40]= 0.000001
Saving checkpoint... 
Iteration: 48017230, states[0] = 32.909381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 60079210, states[0] = 23.508443, states[40]= 0.000002
Saving checkpoint... 
Iteration: 72147419, states[0] = -2.933701, states[40]= 0.000667
Saving checkpoint... 
Iteration: 84178858, states[0] = -20.071076, states[40]= 0.003343
Saving checkpoint... 
Iteration: 96225173, states[0] = -41.645453, states[40]= 0.002180
Saving checkpoint... 
Iteration: 108283549, states[0] = -93.614733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 120281170, states[0] = -93.570699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132399799, states[0] = -94.121038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 144532685, states[0] = -94.264778, states[40]= 0.000001
Saving checkpoint... 
Iteration: 156610691, states[0] = -94.293514, states[40]= 0.000001
Saving checkpoint... 
Iteration: 168732575, states[0] = -94.309068, states[40]= 0.000001
Saving checkpoint... 
Iteration: 180568422, states[0] = -94.282188, states[40]= 0.000001
Saving checkpoint... 
Iteration: 192477529, states[0] = -94.229505, states[40]= 0.000001
Saving checkpoint... 
Iteration: 204607664, states[0] = -94.294080, states[40]= 0.000001
Saving checkpoint... 
Iteration: 216660059, states[0] = -94.303581, states[40]= 0.000001
Saving checkpoint... 
Iteration: 228666873, states[0] = -94.304385, states[40]= 0.000001
Saving checkpoint... 
Iteration: 240788511, states[0] = -94.310953, states[40]= 0.000001
Saving checkpoint... 
Iteration: 252957643, states[0] = -94.307436, states[40]= 0.000001
Saving checkpoint... 
Iteration: 264986068, states[0] = -94.306209, states[40]= 0.000001
Saving checkpoint... 
Iteration: 277067913, states[0] = -94.302727, states[40]= 0.000001
Saving checkpoint... 
Iteration: 289101473, states[0] = -94.301148, states[40]= 0.000001
Saving checkpoint... 
Iteration: 301184359, states[0] = -94.297555, states[40]= 0.000001
Saving checkpoint... 
Iteration: 313052794, states[0] = -94.302763, states[40]= 0.000001
Saving checkpoint... 
Iteration: 325160570, states[0] = -94.298106, states[40]= 0.000001
Saving checkpoint... 
Iteration: 337242700, states[0] = -94.294635, states[40]= 0.000001
Saving checkpoint... 
Iteration: 349461987, states[0] = -94.286821, states[40]= 0.000001
Saving checkpoint... 
Iteration: 361522237, states[0] = 33.556627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 373644184, states[0] = -3.356733, states[40]= 0.000634
Saving checkpoint... 
Iteration: 385761837, states[0] = -80.942471, states[40]= 0.000008
Saving checkpoint... 
Iteration: 397865002, states[0] = -94.042454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 409935685, states[0] = -94.181101, states[40]= 0.000001
Saving checkpoint... 
Iteration: 421942393, states[0] = -94.189541, states[40]= 0.000001
Saving checkpoint... 
Iteration: 434085158, states[0] = -94.284633, states[40]= 0.000001
Saving checkpoint... 
Iteration: 446098929, states[0] = -94.288283, states[40]= 0.000001
Saving checkpoint... 
Iteration: 458154075, states[0] = -94.298910, states[40]= 0.000001
Saving checkpoint... 
Iteration: 470240778, states[0] = -94.305970, states[40]= 0.000001
Saving checkpoint... 
Iteration: 482323958, states[0] = -94.306803, states[40]= 0.000001
Saving checkpoint... 
Iteration: 494408771, states[0] = -94.304846, states[40]= 0.000001
Saving checkpoint... 
Iteration: 506495446, states[0] = -94.301560, states[40]= 0.000001
Saving checkpoint... 
Iteration: 518516279, states[0] = -94.300512, states[40]= 0.000001
Saving checkpoint... 
Iteration: 530599311, states[0] = -94.296875, states[40]= 0.000001
Saving checkpoint... 
Iteration: 542666296, states[0] = -94.293899, states[40]= 0.000001
Saving checkpoint... 
Iteration: 554721619, states[0] = -94.291469, states[40]= 0.000001
Saving checkpoint... 
Iteration: 566797338, states[0] = -94.288373, states[40]= 0.000001
Saving checkpoint... 
Iteration: 578925773, states[0] = -94.283740, states[40]= 0.000001
Saving checkpoint... 
Iteration: 590995369, states[0] = -94.281385, states[40]= 0.000001
Saving checkpoint... 
Iteration: 603028495, states[0] = 34.052557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 614997879, states[0] = -94.280867, states[40]= 0.000001
Saving checkpoint... 
Iteration: 627018373, states[0] = 32.863822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 639137321, states[0] = -0.151819, states[40]= 0.000448
Saving checkpoint... 
Iteration: 651217337, states[0] = -39.433919, states[40]= 0.002763
Saving checkpoint... 
Iteration: 663395435, states[0] = -94.109893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 675535605, states[0] = -94.260775, states[40]= 0.000001
Saving checkpoint... 
Iteration: 687629116, states[0] = -94.290580, states[40]= 0.000001
Saving checkpoint... 
Iteration: 699749995, states[0] = -94.302073, states[40]= 0.000001
Saving checkpoint... 
Iteration: 711889302, states[0] = -94.301395, states[40]= 0.000001
Saving checkpoint... 
Iteration: 723975520, states[0] = -94.298325, states[40]= 0.000001


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_MID_3000-conf_772.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_MID_3000-conf_772_0_r2063394168_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_MID_3000-conf_772_0_r2063394168_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.924420
     * GNaL_b in INaL: 0.006024
     * Gto_b in Ito: 0.082259
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031901
     * GKs_b in IKs: 0.001952
     * GK1_b in IK1: 0.163941
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 70.284513
     * GKb_b in IKb: 0.003782
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030469
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 723975520
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.298325 (After loading)
 - states[40]: 0.000001 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 736109197, states[0] = -94.292683, states[40]= 0.000001
Saving checkpoint... 
Iteration: 748310107, states[0] = -94.284564, states[40]= 0.000001
Saving checkpoint... 
Iteration: 760563940, states[0] = 27.817144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 772860754, states[0] = -94.023322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 785050060, states[0] = -94.265440, states[40]= 0.000001
Saving checkpoint... 
Iteration: 797303924, states[0] = -94.301085, states[40]= 0.000001
Saving checkpoint... 
Iteration: 809637977, states[0] = -94.290145, states[40]= 0.000001
Saving checkpoint... 
Iteration: 821932958, states[0] = -94.279044, states[40]= 0.000001
Saving checkpoint... 
Iteration: 834177465, states[0] = -21.107126, states[40]= 0.003757
Saving checkpoint... 
Iteration: 846523111, states[0] = -94.251022, states[40]= 0.000001
Saving checkpoint... 
Iteration: 858772383, states[0] = -94.299699, states[40]= 0.000001
Saving checkpoint... 
Iteration: 871065300, states[0] = -94.292026, states[40]= 0.000001
Saving checkpoint... 
Iteration: 883374113, states[0] = -94.279843, states[40]= 0.000001
Saving checkpoint... 
Iteration: 895630612, states[0] = 2.715455, states[40]= 0.000291
Saving checkpoint... 
Iteration: 908017085, states[0] = -94.246394, states[40]= 0.000001
Saving checkpoint... 
Iteration: 920334671, states[0] = -94.298648, states[40]= 0.000001
Saving checkpoint... 
Iteration: 932664321, states[0] = -94.286806, states[40]= 0.000001
Saving checkpoint... 
Iteration: 944879466, states[0] = -94.278527, states[40]= 0.000001
Saving checkpoint... 
Iteration: 957115273, states[0] = 8.842884, states[40]= 0.000089
Saving checkpoint... 
Iteration: 969428263, states[0] = -94.160422, states[40]= 0.000001
Saving checkpoint... 
Iteration: 981608042, states[0] = -94.280697, states[40]= 0.000001
Saving checkpoint... 
Iteration: 993963878, states[0] = -94.293798, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1006250969, states[0] = -94.282026, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1018529555, states[0] = 34.075071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1030762790, states[0] = -82.525773, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1043092882, states[0] = -94.275659, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1055456027, states[0] = -94.292954, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1067753720, states[0] = -94.280787, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1080099285, states[0] = 15.053579, states[40]= 0.000021
Saving checkpoint... 
Iteration: 1092384462, states[0] = -94.078423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1104576091, states[0] = -94.269418, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1116840441, states[0] = -94.294957, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1129097487, states[0] = -94.285942, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1141365065, states[0] = -94.275397, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1153595529, states[0] = 16.497353, states[40]= 0.000015
Saving checkpoint... 
Iteration: 1165761191, states[0] = -79.688798, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1177997790, states[0] = -94.228733, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1190297600, states[0] = -94.293850, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1202507731, states[0] = -94.288273, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1214800076, states[0] = -94.276346, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1227079605, states[0] = 22.457973, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1239319016, states[0] = -93.861071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1251640593, states[0] = -94.282235, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1263781257, states[0] = -94.292376, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1276005457, states[0] = -94.287016, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1288249314, states[0] = -94.276903, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1300538079, states[0] = 33.665820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312778833, states[0] = -93.553909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325144957, states[0] = -94.281597, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1337617003, states[0] = -94.281303, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1349910590, states[0] = -94.270044, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1362172502, states[0] = -18.998186, states[40]= 0.002295
Saving checkpoint... 
Iteration: 1374416799, states[0] = -94.135379, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1386694178, states[0] = -94.286309, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1398828924, states[0] = -94.289913, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1411055205, states[0] = -94.282512, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1423243811, states[0] = -94.274630, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1435443817, states[0] = -94.267407, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1447692274, states[0] = -26.577863, states[40]= 0.006710
Saving checkpoint... 
Iteration: 1459855875, states[0] = -93.995849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471913785, states[0] = -94.128606, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1484065672, states[0] = -94.258788, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1496277129, states[0] = -94.288050, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.140472
 - CaMKt in component CaMK (millimolar): 0.004505
 - cass in component intracellular_ions (millimolar): 0.000099
 - nai in component intracellular_ions (millimolar): 7.950650
 - nass in component intracellular_ions (millimolar): 7.950815
 - ki in component intracellular_ions (millimolar): 143.762742
 - kss in component intracellular_ions (millimolar): 143.762723
 - cansr in component intracellular_ions (millimolar): 1.934962
 - cajsr in component intracellular_ions (millimolar): 1.937227
 - cai in component intracellular_ions (millimolar): 0.000104
 - m in component INa (dimensionless): 0.003908
 - hf in component INa (dimensionless): 0.866148
 - hs in component INa (dimensionless): 0.866149
 - j in component INa (dimensionless): 0.866156
 - hsp in component INa (dimensionless): 0.700278
 - jp in component INa (dimensionless): 0.866160
 - mL in component INaL (dimensionless): 0.000057
 - hL in component INaL (dimensionless): 0.708707
 - hLp in component INaL (dimensionless): 0.510368
 - a in component Ito (dimensionless): 0.000656
 - iF in component Ito (dimensionless): 0.999851
 - iS in component Ito (dimensionless): 0.964046
 - ap in component Ito (dimensionless): 0.000334
 - iFp in component Ito (dimensionless): 0.999851
 - iSp in component Ito (dimensionless): 0.981231
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.985634
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004923
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.034089
 - xs1 in component IKs (dimensionless): 0.093628
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997530
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
07:10:12 (64010): called boinc_finish(0)

</stderr_txt>
]]>