𝕏

Task 55754382

Name HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_EPI_4000-conf_572_1
Workunit 26475356
Created 2 Jul 2024, 13:59:09 UTC
Sent 2 Jul 2024, 19:58:49 UTC
Report deadline 5 Jul 2024, 19:58:49 UTC
Received 3 Jul 2024, 5:07:02 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 230398
Run time 2 hours 5 min 36 sec
CPU time 2 hours 4 min 37 sec
Validate state Valid
Credit 43.41
Device peak FLOPS 3.87 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.74 MB
Peak swap size 4.10 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.24.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_EPI_4000-conf_572.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_EPI_4000-conf_572_1_r498707607_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_EPI_4000-conf_572_1_r498707607_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 106.106490
     * GNaL_b in INaL: 0.005988
     * Gto_b in Ito: 0.085160
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031341
     * GKs_b in IKs: 0.001945
     * GK1_b in IK1: 0.167681
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 70.851413
     * GKb_b in IKb: 0.003794
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036944
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12023735, states[0] = 24.986571, states[40]= 0.000392
Saving checkpoint... 
Iteration: 24216173, states[0] = -93.793518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 36319434, states[0] = -94.173212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48271284, states[0] = -94.029237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 60384232, states[0] = -94.261069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 72587128, states[0] = -94.341801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84798822, states[0] = -94.345342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96488356, states[0] = -94.329747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 108382476, states[0] = -94.268802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 120498758, states[0] = -94.336135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132377819, states[0] = -94.266470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 144403408, states[0] = -94.291056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156402380, states[0] = -94.290729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 168368838, states[0] = -94.257909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180410003, states[0] = -94.297186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192462815, states[0] = -94.326972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204498338, states[0] = -94.338954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 216589246, states[0] = -94.353488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 228679753, states[0] = -94.356469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240627007, states[0] = -94.355478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 252434756, states[0] = -94.313173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 264447723, states[0] = -94.319869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 276587933, states[0] = -94.352916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 288669600, states[0] = -94.355893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 300707716, states[0] = -94.355621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 312667543, states[0] = -94.355608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324658399, states[0] = -94.355375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 336711985, states[0] = -94.355146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 348739012, states[0] = -94.354506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 360745472, states[0] = -94.354211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 372604034, states[0] = -94.352928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384584321, states[0] = -94.351364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396707398, states[0] = -94.354489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408719465, states[0] = -94.354172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 420701933, states[0] = -94.354260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432753979, states[0] = -94.353131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 444839743, states[0] = -94.350093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 456870981, states[0] = -94.348705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 468932301, states[0] = -94.346018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 480882437, states[0] = -94.347945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 492913391, states[0] = -94.346515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 504987654, states[0] = -94.343273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516978302, states[0] = -94.343515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528978406, states[0] = -94.343365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 541030225, states[0] = -94.341100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553102625, states[0] = -94.338124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565176060, states[0] = -94.335298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 577235026, states[0] = -94.333146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 589332929, states[0] = -94.329953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 601373879, states[0] = -94.328633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 613444122, states[0] = -94.326598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 625519886, states[0] = -94.324583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 637566649, states[0] = -94.323363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649625537, states[0] = -94.321946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661633927, states[0] = -94.321626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673798380, states[0] = -94.318381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685961644, states[0] = -94.315679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 697939636, states[0] = -94.315850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709959528, states[0] = -94.315417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721980033, states[0] = -94.314981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 733915615, states[0] = -94.315768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 745876596, states[0] = -94.316221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 757940202, states[0] = -94.315112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 769958361, states[0] = -94.314703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 781932259, states[0] = -94.314938, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_EPI_4000-conf_572.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_EPI_4000-conf_572_1_r498707607_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_EPI_4000-conf_572_1_r498707607_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 106.106490
     * GNaL_b in INaL: 0.005988
     * Gto_b in Ito: 0.085160
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031341
     * GKs_b in IKs: 0.001945
     * GK1_b in IK1: 0.167681
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 70.851413
     * GKb_b in IKb: 0.003794
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036944
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 781932259
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.314938 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 794209554, states[0] = -93.698478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 806589017, states[0] = -94.346637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 818894408, states[0] = -94.343352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 830920975, states[0] = -94.342100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 843163980, states[0] = -94.332353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 855494407, states[0] = -94.322400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 867717564, states[0] = -94.317474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879867886, states[0] = -94.314733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 892132718, states[0] = -24.792800, states[40]= 0.000404
Saving checkpoint... 
Iteration: 904399811, states[0] = -94.281194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 916692960, states[0] = -94.348324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 929011448, states[0] = -94.337159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 941286492, states[0] = -94.327088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953579248, states[0] = -94.319247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 965849183, states[0] = -94.313988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 978152938, states[0] = -47.270518, states[40]= 0.000143
Saving checkpoint... 
Iteration: 990395389, states[0] = -94.276353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002560418, states[0] = -94.341431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014868748, states[0] = -94.342029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1027107765, states[0] = -94.332181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1039414100, states[0] = -94.322214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1051612580, states[0] = -94.317335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1063888528, states[0] = -94.312174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1076143962, states[0] = -36.892449, states[40]= 0.000367
Saving checkpoint... 
Iteration: 1088400883, states[0] = -94.279849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1100623679, states[0] = -94.345098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112767049, states[0] = -94.344530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124968666, states[0] = -94.336546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137247325, states[0] = -94.325951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149530995, states[0] = -94.317959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1161654405, states[0] = -94.315132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1173927012, states[0] = -94.310253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186132459, states[0] = -24.517478, states[40]= 0.000397
Saving checkpoint... 
Iteration: 1198454145, states[0] = -94.311639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210680502, states[0] = -94.344797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1222907992, states[0] = -94.337889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1235095239, states[0] = -94.330131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1247410443, states[0] = -94.319786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1259747940, states[0] = -94.312150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1271927362, states[0] = -94.309057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284226232, states[0] = -93.805406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296477091, states[0] = -94.319603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1308733923, states[0] = -94.342996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1321001775, states[0] = -94.332798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333175155, states[0] = -94.326012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345431381, states[0] = -94.318040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1357723878, states[0] = -94.311401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369963024, states[0] = -94.307346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1382269494, states[0] = -94.020922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394545178, states[0] = -94.334613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406775033, states[0] = -94.340720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1418920361, states[0] = -94.334994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431209354, states[0] = -94.323640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443467552, states[0] = -94.315923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1455736680, states[0] = -94.309974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1468049135, states[0] = 25.131856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1480399555, states[0] = -94.273974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1492638031, states[0] = -94.340830, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.181220
 - CaMKt in component CaMK (millimolar): 0.002322
 - cass in component intracellular_ions (millimolar): 0.000101
 - nai in component intracellular_ions (millimolar): 7.118285
 - nass in component intracellular_ions (millimolar): 7.118421
 - ki in component intracellular_ions (millimolar): 144.557136
 - kss in component intracellular_ions (millimolar): 144.557121
 - cansr in component intracellular_ions (millimolar): 2.410694
 - cajsr in component intracellular_ions (millimolar): 2.411166
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.003892
 - hf in component INa (dimensionless): 0.866922
 - hs in component INa (dimensionless): 0.866923
 - j in component INa (dimensionless): 0.866926
 - hsp in component INa (dimensionless): 0.701677
 - jp in component INa (dimensionless): 0.866928
 - mL in component INaL (dimensionless): 0.000057
 - hL in component INaL (dimensionless): 0.709784
 - hLp in component INaL (dimensionless): 0.516150
 - a in component Ito (dimensionless): 0.000654
 - iF in component Ito (dimensionless): 0.999852
 - iS in component Ito (dimensionless): 0.999852
 - ap in component Ito (dimensionless): 0.000333
 - iFp in component Ito (dimensionless): 0.999852
 - iSp in component Ito (dimensionless): 0.999852
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.996727
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005245
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.006627
 - xs1 in component IKs (dimensionless): 0.039930
 - xs2 in component IKs (dimensionless): 0.000095
 - xk1 in component IK1 (dimensionless): 0.997520
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
06:05:50 (63557): called boinc_finish(0)

</stderr_txt>
]]>


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