𝕏

Task 55752915

Name HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pieske_1000-conf_270_1
Workunit 26474669
Created 2 Jul 2024, 13:58:27 UTC
Sent 2 Jul 2024, 19:39:11 UTC
Report deadline 5 Jul 2024, 19:39:11 UTC
Received 4 Jul 2024, 3:16:58 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241050
Run time 3 hours 1 min 17 sec
CPU time 1 hours 29 min 34 sec
Validate state Valid
Credit 44.19
Device peak FLOPS 6.58 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.38 MB
Peak swap size 3.89 MB
Peak disk usage 0.34 MB

Stderr output

<core_client_version>7.16.16</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pieske_1000-conf_270.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pieske_1000-conf_270_1_r1378926046_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pieske_1000-conf_270_1_r1378926046_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 106.791328
     * GNaL_b in INaL: 0.005842
     * Gto_b in Ito: 0.081042
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032076
     * GKs_b in IKs: 0.001918
     * GK1_b in IK1: 0.165386
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 69.446835
     * GKb_b in IKb: 0.003782
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036197
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 8966687, states[0] = -87.113255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17770549, states[0] = -86.980180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25722787, states[0] = -86.888078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35042227, states[0] = 14.044530, states[40]= 0.004948
Saving checkpoint... 
Iteration: 43021103, states[0] = 21.426660, states[40]= 0.007926
Saving checkpoint... 
Iteration: 51280533, states[0] = -86.912626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59640433, states[0] = -68.435118, states[40]= 0.000001
Saving checkpoint... 
Iteration: 68382882, states[0] = -86.958842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 76195321, states[0] = -86.766116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84952892, states[0] = -86.967882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 92949601, states[0] = -86.964277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 101129387, states[0] = -53.377309, states[40]= 0.000014
Saving checkpoint... 
Iteration: 109682793, states[0] = -86.728848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117659815, states[0] = -86.047066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 126319328, states[0] = -86.908604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133754746, states[0] = -86.848209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143231508, states[0] = -86.814814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 151215601, states[0] = -86.787753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 159199773, states[0] = -86.757810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167763424, states[0] = -86.856379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176923131, states[0] = -86.948204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 184459101, states[0] = -86.955341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 193879978, states[0] = -86.934914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201733092, states[0] = -86.815028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 209493915, states[0] = -86.959936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 218408720, states[0] = -86.943748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226224036, states[0] = -86.800292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 234299186, states[0] = -86.889730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 241409305, states[0] = -86.943747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 249524509, states[0] = 20.941949, states[40]= 0.006681
Saving checkpoint... 
Iteration: 257695635, states[0] = -86.748076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266271685, states[0] = -86.864173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 274167138, states[0] = -86.604286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 281730563, states[0] = -86.810599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 289411455, states[0] = -86.944184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 297489444, states[0] = -86.958964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 305707062, states[0] = -86.769961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314486749, states[0] = -86.958595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 323132179, states[0] = -56.019937, states[40]= 0.000009
Saving checkpoint... 
Iteration: 332053747, states[0] = 10.071971, states[40]= 0.004791
Saving checkpoint... 
Iteration: 340188384, states[0] = -86.733492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 348838537, states[0] = -86.915629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 356769104, states[0] = -86.861276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366844494, states[0] = -86.918764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374955799, states[0] = -86.953839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382865453, states[0] = -86.928492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 391896992, states[0] = -86.939894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399708961, states[0] = -86.773412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 407678705, states[0] = -86.711587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 416551163, states[0] = 11.160878, states[40]= 0.004813
Saving checkpoint... 
Iteration: 424428720, states[0] = -86.948351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432777851, states[0] = -86.870308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 440973435, states[0] = -86.956645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449378873, states[0] = -86.933724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457752331, states[0] = -86.841403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467053918, states[0] = 9.999380, states[40]= 0.004790
Saving checkpoint... 
Iteration: 475303718, states[0] = -86.892934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 483155172, states[0] = -84.320038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491040548, states[0] = 15.451474, states[40]= 0.004994
Saving checkpoint... 
Iteration: 499034608, states[0] = 17.689379, states[40]= 0.005276
Saving checkpoint... 
Iteration: 506843240, states[0] = -86.918019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514962567, states[0] = -86.954896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 522801514, states[0] = -86.891192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 530789959, states[0] = -86.881578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 538909420, states[0] = -86.943425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547224502, states[0] = -86.800602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 555393413, states[0] = -86.938655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 564451159, states[0] = -86.952874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 573281760, states[0] = -86.874025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 581429479, states[0] = -86.948419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590301574, states[0] = -86.891195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 600136950, states[0] = -61.700475, states[40]= 0.000003
Saving checkpoint... 
Iteration: 607861676, states[0] = -86.926728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617413345, states[0] = -86.944433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 625556913, states[0] = 8.707067, states[40]= 0.004762
Saving checkpoint... 
Iteration: 633555288, states[0] = 9.412512, states[40]= 0.004778
Saving checkpoint... 
Iteration: 641713692, states[0] = -86.781881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649631279, states[0] = -54.988201, states[40]= 0.000011
Saving checkpoint... 
Iteration: 658031957, states[0] = 18.625756, states[40]= 0.005484
Saving checkpoint... 
Iteration: 665855936, states[0] = -86.924123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674072865, states[0] = 0.862221, states[40]= 0.004277
Saving checkpoint... 
Iteration: 683323704, states[0] = -86.906709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 691612297, states[0] = -34.758011, states[40]= 0.000238
Saving checkpoint... 
Iteration: 698963079, states[0] = -86.954859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 708302259, states[0] = -86.891651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 716686300, states[0] = -86.728972, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724501435, states[0] = 41.747023, states[40]= 0.074560
Saving checkpoint... 
Iteration: 733195731, states[0] = -86.747848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741531024, states[0] = 18.943516, states[40]= 0.005575
Saving checkpoint... 
Iteration: 750522602, states[0] = 21.440097, states[40]= 0.007321
Saving checkpoint... 
Iteration: 758584372, states[0] = -7.115330, states[40]= 0.002906
Saving checkpoint... 
Iteration: 766471189, states[0] = -86.956093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 774878905, states[0] = -86.933520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 784036629, states[0] = 16.946946, states[40]= 0.005157
Saving checkpoint... 
Iteration: 791647874, states[0] = -76.739416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 800372057, states[0] = -86.930895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 809082236, states[0] = -5.387225, states[40]= 0.003264
Saving checkpoint... 
Iteration: 817183068, states[0] = -86.722035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 825775131, states[0] = -86.867304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 834943145, states[0] = -86.951159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 844129794, states[0] = -53.308607, states[40]= 0.000014
Saving checkpoint... 
Iteration: 852287219, states[0] = -86.878918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 860577265, states[0] = -1.832946, states[40]= 0.003912
Saving checkpoint... 
Iteration: 868872227, states[0] = -86.930917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 877565643, states[0] = 4.680288, states[40]= 0.004602
Saving checkpoint... 
Iteration: 886292938, states[0] = -86.883926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 894676240, states[0] = -86.703233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 903000046, states[0] = -81.277752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 911303563, states[0] = -86.892525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 919446578, states[0] = -86.951776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 928227968, states[0] = -86.805996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 936769973, states[0] = -86.861823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 945002406, states[0] = 36.547724, states[40]= 0.132791
Saving checkpoint... 
Iteration: 953323062, states[0] = -86.906125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 961637514, states[0] = -62.403168, states[40]= 0.000003
Saving checkpoint... 
Iteration: 969412484, states[0] = -86.943970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977831645, states[0] = -86.911323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 985436436, states[0] = -86.949679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 994124536, states[0] = -47.522196, states[40]= 0.000036
Saving checkpoint... 
Iteration: 1002811214, states[0] = -86.898128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011050408, states[0] = 11.475489, states[40]= 0.004820
Saving checkpoint... 
Iteration: 1019281214, states[0] = -86.873204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1028037038, states[0] = 16.794131, states[40]= 0.005136
Saving checkpoint... 
Iteration: 1036011242, states[0] = 23.425897, states[40]= 0.034423
Saving checkpoint... 
Iteration: 1043874082, states[0] = -86.931523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052000164, states[0] = -66.768573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1060238167, states[0] = -86.821569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1068222041, states[0] = -86.796143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1076593585, states[0] = -15.766863, states[40]= 0.001337
Saving checkpoint... 
Iteration: 1084264554, states[0] = -86.855735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1092382898, states[0] = -86.934753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1100076991, states[0] = -1.654059, states[40]= 0.003940
Saving checkpoint... 
Iteration: 1107878847, states[0] = -86.933278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116324621, states[0] = -86.906996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1125480695, states[0] = -86.957230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1133193276, states[0] = -86.742734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141679236, states[0] = -86.712566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149738662, states[0] = -86.822233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1157141050, states[0] = -67.014850, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1164985140, states[0] = -86.957803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1173691564, states[0] = -86.739305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1181624201, states[0] = -47.160477, states[40]= 0.000038
Saving checkpoint... 
Iteration: 1189869716, states[0] = -86.929706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197708658, states[0] = -86.772314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205630066, states[0] = -53.613952, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1213782932, states[0] = -86.874712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1222015731, states[0] = 22.812630, states[40]= 0.014431
Saving checkpoint... 
Iteration: 1230103675, states[0] = -26.005862, states[40]= 0.000595
Saving checkpoint... 
Iteration: 1237853978, states[0] = -86.922835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245374532, states[0] = -86.931563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253032403, states[0] = 18.471720, states[40]= 0.005444
Saving checkpoint... 
Iteration: 1263447640, states[0] = -86.951751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1272807816, states[0] = -86.895486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1281140919, states[0] = -66.837013, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1289763277, states[0] = -86.854139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298792088, states[0] = -86.882922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306869710, states[0] = -86.929626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1315559672, states[0] = 7.482769, states[40]= 0.004727
Saving checkpoint... 
Iteration: 1324031212, states[0] = 18.880172, states[40]= 0.005555
Saving checkpoint... 
Iteration: 1332460895, states[0] = -86.954077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340897977, states[0] = -86.939566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1348950664, states[0] = -86.952263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1356871044, states[0] = -86.930126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1364888630, states[0] = -86.936549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374204206, states[0] = -86.763829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1382746679, states[0] = -86.833345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392093842, states[0] = -16.025201, states[40]= 0.001304
Saving checkpoint... 
Iteration: 1400179547, states[0] = -86.713226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1407623395, states[0] = -46.293730, states[40]= 0.000044
Saving checkpoint... 
Iteration: 1415897219, states[0] = -86.939283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424230791, states[0] = -86.810143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1432465897, states[0] = -86.954829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1440731030, states[0] = -86.810506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1449696452, states[0] = -86.748783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456922911, states[0] = -86.946299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1465483774, states[0] = -86.957423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1474655068, states[0] = -84.257482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483201185, states[0] = -86.757971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1492691687, states[0] = -86.739336, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.835276
 - CaMKt in component CaMK (millimolar): 0.006616
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.432849
 - nass in component intracellular_ions (millimolar): 6.432905
 - ki in component intracellular_ions (millimolar): 145.552931
 - kss in component intracellular_ions (millimolar): 145.552913
 - cansr in component intracellular_ions (millimolar): 1.285992
 - cajsr in component intracellular_ions (millimolar): 1.248572
 - cai in component intracellular_ions (millimolar): 0.000073
 - m in component INa (dimensionless): 0.008156
 - hf in component INa (dimensionless): 0.660832
 - hs in component INa (dimensionless): 0.660821
 - j in component INa (dimensionless): 0.660761
 - hsp in component INa (dimensionless): 0.412926
 - jp in component INa (dimensionless): 0.660719
 - mL in component INaL (dimensionless): 0.000229
 - hL in component INaL (dimensionless): 0.466222
 - hLp in component INaL (dimensionless): 0.241395
 - a in component Ito (dimensionless): 0.001074
 - iF in component Ito (dimensionless): 0.999465
 - iS in component Ito (dimensionless): 0.580139
 - ap in component Ito (dimensionless): 0.000547
 - iFp in component Ito (dimensionless): 0.999465
 - iSp in component Ito (dimensionless): 0.634992
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935891
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999895
 - jca in component ICaL (dimensionless): 0.999980
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001500
 - xrf in component IKr (dimensionless): 0.000009
 - xrs in component IKr (dimensionless): 0.408558
 - xs1 in component IKs (dimensionless): 0.239957
 - xs2 in component IKs (dimensionless): 0.000217
 - xk1 in component IK1 (dimensionless): 0.997022
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
04:07:37 (65857): called boinc_finish(0)

</stderr_txt>
]]>


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