𝕏

Task 55752644

Name HuVeMOp_20240702153647868011_ORdGradInc_k_26-Coppini_5000-conf_70_0
Workunit 26474534
Created 2 Jul 2024, 13:58:22 UTC
Sent 2 Jul 2024, 19:39:26 UTC
Report deadline 5 Jul 2024, 19:39:26 UTC
Received 5 Jul 2024, 23:09:06 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 242052
Run time 1 hours 40 min 55 sec
CPU time 1 hours 19 min 1 sec
Validate state Valid
Credit 50.70
Device peak FLOPS 3.73 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.79 MB
Peak swap size 5.32 MB
Peak disk usage 1.55 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Coppini_5000-conf_70.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Coppini_5000-conf_70_0_r1532849204_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Coppini_5000-conf_70_0_r1532849204_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 100.262983
     * GNaL_b in INaL: 0.005455
     * Gto_b in Ito: 0.084349
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031604
     * GKs_b in IKs: 0.001944
     * GK1_b in IK1: 0.167391
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 70.327540
     * GKb_b in IKb: 0.003780
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035325
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1497500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 10288187, states[0] = -94.516240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 20083346, states[0] = 6.918069, states[40]= 0.004355
Saving checkpoint... 
Iteration: 30030098, states[0] = 25.006827, states[40]= 0.001946
Saving checkpoint... 
Iteration: 39864318, states[0] = -94.554313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 49640326, states[0] = -94.539527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59788533, states[0] = -94.527499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68942341, states[0] = -94.528157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 78446517, states[0] = -94.531363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 88058905, states[0] = -94.512347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98130634, states[0] = -94.518662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 105926036, states[0] = -94.522434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 114364460, states[0] = -94.506875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 123686959, states[0] = -94.514526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133797461, states[0] = -94.511262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143858449, states[0] = -94.509257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153738877, states[0] = -94.510546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 163834387, states[0] = -94.508282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 173692235, states[0] = -94.510331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183302639, states[0] = -94.515617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192752520, states[0] = -94.186182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 202491858, states[0] = -94.496379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 211012542, states[0] = -94.512705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 219844731, states[0] = -94.496789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 228999894, states[0] = -94.504023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 237851453, states[0] = -94.386702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 247362815, states[0] = -94.496409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 254899424, states[0] = -94.496173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 263760131, states[0] = -94.507533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 272581525, states[0] = 9.812680, states[40]= 0.004327
Saving checkpoint... 
Iteration: 282833953, states[0] = -94.363331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292977778, states[0] = -94.476416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 300622245, states[0] = -94.507004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 310670096, states[0] = -94.510722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 320767240, states[0] = -94.513952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 330885266, states[0] = -94.513895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 340983584, states[0] = -94.512479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 350589774, states[0] = -94.503108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 360037832, states[0] = 24.132511, states[40]= 0.001974
Saving checkpoint... 
Iteration: 369821280, states[0] = -94.496273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374815597, states[0] = -94.496298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384946473, states[0] = -94.495631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 394789968, states[0] = -94.496419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404898398, states[0] = -94.495844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 414991434, states[0] = -94.495399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424392198, states[0] = -94.499147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434356953, states[0] = -94.499449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443787868, states[0] = -94.506733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 453626300, states[0] = -94.509705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 463246551, states[0] = -94.513460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 473155584, states[0] = -94.509611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 483169170, states[0] = -94.510487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 492777645, states[0] = -94.255193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 501964611, states[0] = -94.498492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 511647663, states[0] = -94.501523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521578406, states[0] = -94.502348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 531822614, states[0] = -94.499691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 541839019, states[0] = -94.499533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 552030217, states[0] = -94.497956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562583135, states[0] = 9.117427, states[40]= 0.004381
Saving checkpoint... 
Iteration: 572708107, states[0] = -93.619884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582631782, states[0] = -23.100968, states[40]= 0.001515
Saving checkpoint... 
Iteration: 591196603, states[0] = -94.508272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 600144265, states[0] = -33.014802, states[40]= 0.000999
Saving checkpoint... 
Iteration: 609209636, states[0] = -94.500766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 618478219, states[0] = -94.512346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 628023766, states[0] = -94.490418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 637395650, states[0] = -94.495687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646304440, states[0] = -94.506302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 655889328, states[0] = -94.513587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 665681230, states[0] = -94.511034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 675789399, states[0] = -94.513877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685436915, states[0] = -94.457284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696518505, states[0] = -94.503001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706219864, states[0] = -94.507761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 717105157, states[0] = -94.497312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727511147, states[0] = 26.610808, states[40]= 0.032737
Saving checkpoint... 
Iteration: 738092177, states[0] = -94.503137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 748067966, states[0] = -94.499493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 758700680, states[0] = -94.508078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 769254466, states[0] = -94.500186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779848822, states[0] = -94.495824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 790120585, states[0] = -13.990124, states[40]= 0.001788
Saving checkpoint... 
Iteration: 800475571, states[0] = -94.475118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 810505776, states[0] = -94.485374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 820630624, states[0] = -94.507359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 830784769, states[0] = -94.513733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 840158749, states[0] = -45.044684, states[40]= 0.000214
Saving checkpoint... 
Iteration: 849873655, states[0] = -94.495647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 860050995, states[0] = 20.643091, states[40]= 0.002642
Saving checkpoint... 
Iteration: 869863025, states[0] = -94.495687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879406726, states[0] = -94.498697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889471948, states[0] = -94.498159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 899852679, states[0] = -94.495719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 910215848, states[0] = -94.018228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 920618917, states[0] = -94.506154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 930640235, states[0] = -94.508117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940172889, states[0] = -57.572345, states[40]= 0.000029
Saving checkpoint... 
Iteration: 950498638, states[0] = -94.483094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 960865362, states[0] = -94.513591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 971139595, states[0] = -94.509083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980085974, states[0] = 7.848431, states[40]= 0.004461
Saving checkpoint... 
Iteration: 990749089, states[0] = -94.513136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1001160590, states[0] = -94.508661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010882170, states[0] = -94.513408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021005840, states[0] = -94.511579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031057294, states[0] = -94.510618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041116116, states[0] = -94.509484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1050782865, states[0] = -94.513561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1060572289, states[0] = -94.499983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070643256, states[0] = -94.508263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1080637716, states[0] = -94.507800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090748706, states[0] = -94.513058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1101011711, states[0] = -94.511416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1111119493, states[0] = -94.509369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121681035, states[0] = -94.500714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1132032014, states[0] = -94.497532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142287671, states[0] = -94.495895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1152615408, states[0] = -9.781968, states[40]= 0.002531
Saving checkpoint... 
Iteration: 1163004942, states[0] = -94.484877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1173516080, states[0] = -94.511286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183917295, states[0] = -94.504103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1194253115, states[0] = -94.499899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1204736144, states[0] = -94.496143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215085511, states[0] = 8.058789, states[40]= 0.004449
Saving checkpoint... 
Iteration: 1225235178, states[0] = -94.127069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1235607427, states[0] = -94.504679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245807770, states[0] = -94.513561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1255989742, states[0] = -94.511697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1266380299, states[0] = -94.504617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276764872, states[0] = -94.499722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1286710667, states[0] = -94.500275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296589764, states[0] = -94.501658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306748720, states[0] = -94.499864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1316900221, states[0] = -94.498443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1326868577, states[0] = -94.498711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336966248, states[0] = -94.497887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1347144006, states[0] = -94.496609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1357236753, states[0] = -94.496032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1366998764, states[0] = -94.497614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1376898885, states[0] = -94.498412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1386648648, states[0] = -94.500892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1396690002, states[0] = -94.500421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406825572, states[0] = -94.499044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1416904612, states[0] = -94.498335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1427040998, states[0] = -94.497258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1436980908, states[0] = -94.497702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447101629, states[0] = -94.496819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457138602, states[0] = -94.496566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1467204463, states[0] = -94.496146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1477315068, states[0] = -94.495508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486448072, states[0] = -94.503431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1496304796, states[0] = -94.505695, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.370563
 - CaMKt in component CaMK (millimolar): 0.001120
 - cass in component intracellular_ions (millimolar): 0.000087
 - nai in component intracellular_ions (millimolar): 6.312624
 - nass in component intracellular_ions (millimolar): 6.312709
 - ki in component intracellular_ions (millimolar): 145.613300
 - kss in component intracellular_ions (millimolar): 145.613290
 - cansr in component intracellular_ions (millimolar): 1.563023
 - cajsr in component intracellular_ions (millimolar): 1.563070
 - cai in component intracellular_ions (millimolar): 0.000089
 - m in component INa (dimensionless): 0.003818
 - hf in component INa (dimensionless): 0.870470
 - hs in component INa (dimensionless): 0.870471
 - j in component INa (dimensionless): 0.870472
 - hsp in component INa (dimensionless): 0.708146
 - jp in component INa (dimensionless): 0.870472
 - mL in component INaL (dimensionless): 0.000055
 - hL in component INaL (dimensionless): 0.714937
 - hLp in component INaL (dimensionless): 0.522784
 - a in component Ito (dimensionless): 0.000646
 - iF in component Ito (dimensionless): 0.999857
 - iS in component Ito (dimensionless): 0.997768
 - ap in component Ito (dimensionless): 0.000329
 - iFp in component Ito (dimensionless): 0.999857
 - iSp in component Ito (dimensionless): 0.999263
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998873
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002970
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001760
 - xs1 in component IKs (dimensionless): 0.022678
 - xs2 in component IKs (dimensionless): 0.000093
 - xk1 in component IK1 (dimensionless): 0.997473
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
18:33:06 (14236): called boinc_finish(0)

</stderr_txt>
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