𝕏

Task 55750883

Name HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pueyo_APDR-conf_867_0
Workunit 26473659
Created 2 Jul 2024, 13:57:30 UTC
Sent 2 Jul 2024, 19:23:57 UTC
Report deadline 6 Jul 2024, 4:59:57 UTC
Received 4 Jul 2024, 4:28:10 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 214641
Run time 2 hours 44 min 26 sec
CPU time 2 hours 44 min 26 sec
Validate state Valid
Credit 59.15
Device peak FLOPS 3.78 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.15 MB
Peak swap size 6.23 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pueyo_APDR-conf_867.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pueyo_APDR-conf_867_0_r859801163_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pueyo_APDR-conf_867_0_r859801163_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 104.878017
     * GNaL_b in INaL: 0.005438
     * Gto_b in Ito: 0.081581
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032105
     * GKs_b in IKs: 0.001952
     * GK1_b in IK1: 0.162172
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 70.260684
     * GKb_b in IKb: 0.003785
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035407
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12964656, states[0] = -95.099693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25932413, states[0] = -95.062042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 37593596, states[0] = -17.236212, states[40]= 0.001207
Saving checkpoint... 
Iteration: 50455801, states[0] = -95.037414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 61250165, states[0] = -94.921114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 74237060, states[0] = -94.897713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 86608375, states[0] = -30.053899, states[40]= 0.000448
Saving checkpoint... 
Iteration: 99752298, states[0] = -94.911403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 112546040, states[0] = 12.662919, states[40]= 0.005122
Saving checkpoint... 
Iteration: 125308799, states[0] = -94.961057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 138415466, states[0] = -95.006215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 151442305, states[0] = -95.011564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 164216510, states[0] = -94.853613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176910110, states[0] = -95.003595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 190223214, states[0] = -94.864481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 202940922, states[0] = -95.010300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215453124, states[0] = -95.012482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 228608667, states[0] = -29.845090, states[40]= 0.000458
Saving checkpoint... 
Iteration: 241747755, states[0] = -94.899943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 253494600, states[0] = -95.018371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266150321, states[0] = -77.493069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279745600, states[0] = -94.897055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 293660051, states[0] = -91.765465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 306920296, states[0] = -95.005495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 319982925, states[0] = -95.016810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 332830763, states[0] = -94.971925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 345379641, states[0] = -94.993654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358429441, states[0] = -95.007547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 371057381, states[0] = 8.102987, states[40]= 0.004906
Saving checkpoint... 
Iteration: 383654257, states[0] = -84.233140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396569172, states[0] = 2.633960, states[40]= 0.004568
Saving checkpoint... 
Iteration: 409410190, states[0] = -95.002890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422239925, states[0] = -94.889255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 435807456, states[0] = -94.957254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449069289, states[0] = 2.574017, states[40]= 0.004562
Saving checkpoint... 
Iteration: 462425313, states[0] = -95.006559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 475690668, states[0] = -94.802462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 488593349, states[0] = -15.026846, states[40]= 0.001468
Saving checkpoint... 
Iteration: 501326861, states[0] = -94.969600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514037098, states[0] = 16.096607, states[40]= 0.005517
Saving checkpoint... 
Iteration: 527537475, states[0] = 15.960766, states[40]= 0.005492
Saving checkpoint... 
Iteration: 540610256, states[0] = -31.383245, states[40]= 0.000389
Saving checkpoint... 
Iteration: 554348404, states[0] = -94.980827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566946644, states[0] = -95.010906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579609437, states[0] = -30.585822, states[40]= 0.000425
Saving checkpoint... 
Iteration: 591277723, states[0] = -94.932852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 604456175, states[0] = -95.012588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617424676, states[0] = -95.006321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 630031879, states[0] = 17.896622, states[40]= 0.005991
Saving checkpoint... 
Iteration: 642977424, states[0] = -95.015858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 656275943, states[0] = -94.931112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 669325145, states[0] = -94.968496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 682687592, states[0] = -94.795520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 695567730, states[0] = 3.361523, states[40]= 0.004632
Saving checkpoint... 
Iteration: 708944296, states[0] = -95.010378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 722526367, states[0] = 19.591050, states[40]= 0.006943
Saving checkpoint... 
Iteration: 735983417, states[0] = -95.016617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 749472253, states[0] = -95.015052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763200682, states[0] = -94.822867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 776565403, states[0] = 4.494000, states[40]= 0.004717
Saving checkpoint... 
Iteration: 790388562, states[0] = -94.996372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802807258, states[0] = -94.956894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 816542984, states[0] = 13.906843, states[40]= 0.005217
Saving checkpoint... 
Iteration: 829792211, states[0] = -94.945464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 843234924, states[0] = -94.881855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 856730149, states[0] = -94.874684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 870530519, states[0] = 18.336985, states[40]= 0.006167
Saving checkpoint... 
Iteration: 884410892, states[0] = -95.002788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898212339, states[0] = -94.844882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 911682669, states[0] = -94.782702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 925483375, states[0] = -95.016498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 939189476, states[0] = -94.799589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 952683415, states[0] = -94.784863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966260707, states[0] = -94.915028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 979893905, states[0] = -94.997933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 993316263, states[0] = -94.962835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1006787394, states[0] = -94.941323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020274881, states[0] = -94.929864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1034140042, states[0] = -63.035107, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1048006425, states[0] = 26.087669, states[40]= 0.115888
Saving checkpoint... 
Iteration: 1061475998, states[0] = -95.015406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1075244240, states[0] = -94.894745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1088688392, states[0] = -94.797091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102433592, states[0] = -95.007992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1115952310, states[0] = -95.011609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1129624204, states[0] = -45.405137, states[40]= 0.000055
Saving checkpoint... 
Iteration: 1143250822, states[0] = -94.903196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156709034, states[0] = -94.838664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170215362, states[0] = -94.850117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183677920, states[0] = -94.762511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197133391, states[0] = -55.374561, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1210505030, states[0] = 28.817695, states[40]= 0.142574
Saving checkpoint... 
Iteration: 1223958354, states[0] = -95.012585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1237844829, states[0] = -94.978707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1251625144, states[0] = -46.399747, states[40]= 0.000047
Saving checkpoint... 
Iteration: 1265383300, states[0] = -94.994355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278882422, states[0] = -94.994049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1292591914, states[0] = -13.666651, states[40]= 0.001671
Saving checkpoint... 
Iteration: 1306462788, states[0] = -95.013263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1320226319, states[0] = -94.868413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333836528, states[0] = -94.974444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1347421522, states[0] = -95.005149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1360727167, states[0] = -94.869734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1373816769, states[0] = -94.962931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387018178, states[0] = 21.592129, states[40]= 0.012045
Saving checkpoint... 
Iteration: 1400172197, states[0] = -94.686099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1413780755, states[0] = -94.935184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1427658655, states[0] = -90.475184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1441527741, states[0] = 19.192270, states[40]= 0.006635
Saving checkpoint... 
Iteration: 1455405540, states[0] = -95.001016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1469185165, states[0] = -94.789222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482821197, states[0] = -94.965637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1496571199, states[0] = 1.573062, states[40]= 0.004462


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pueyo_APDR-conf_867.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pueyo_APDR-conf_867_0_r859801163_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pueyo_APDR-conf_867_0_r859801163_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 104.878017
     * GNaL_b in INaL: 0.005438
     * Gto_b in Ito: 0.081581
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032105
     * GKs_b in IKs: 0.001952
     * GK1_b in IK1: 0.162172
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 70.260684
     * GKb_b in IKb: 0.003785
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035407
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1496571199
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 1.573062 (After loading)
 - states[40]: 0.004462 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1510307382, states[0] = -45.466484, states[40]= 0.000055
Saving checkpoint... 
Iteration: 1524139257, states[0] = -91.823277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1537825323, states[0] = 19.120685, states[40]= 0.008378
Saving checkpoint... 
Iteration: 1551564499, states[0] = -95.259433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1565339488, states[0] = -95.238631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1579177424, states[0] = -95.278867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1592540064, states[0] = -93.564602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1606434141, states[0] = -95.238980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1619223487, states[0] = -69.760266, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1632966192, states[0] = -3.700588, states[40]= 0.004123
Saving checkpoint... 
Iteration: 1646522712, states[0] = -68.676688, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1660165985, states[0] = -95.274793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1673689740, states[0] = -95.293552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1687318115, states[0] = -62.284621, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1701096055, states[0] = -35.608053, states[40]= 0.000232
Saving checkpoint... 
Iteration: 1714532348, states[0] = 15.919286, states[40]= 0.006875
Saving checkpoint... 
Iteration: 1728255778, states[0] = -95.265544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1742078890, states[0] = -95.285825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1754250674, states[0] = -95.025931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1767716112, states[0] = -59.675475, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1781503589, states[0] = -44.260188, states[40]= 0.000068
Saving checkpoint... 
Iteration: 1794982170, states[0] = -20.108081, states[40]= 0.001034
Saving checkpoint... 
Iteration: 1807092663, states[0] = -17.701866, states[40]= 0.001187
Saving checkpoint... 
Iteration: 1820758272, states[0] = -94.949267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1834255162, states[0] = -94.934047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1848032105, states[0] = 17.610906, states[40]= 0.005954
Saving checkpoint... 
Iteration: 1861872550, states[0] = -95.001550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1875641151, states[0] = -65.060004, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1889051022, states[0] = 10.656052, states[40]= 0.005014
Saving checkpoint... 
Iteration: 1902458059, states[0] = -95.015526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1914871652, states[0] = -94.992159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1928592710, states[0] = -14.506058, states[40]= 0.001543
Saving checkpoint... 
Iteration: 1940896701, states[0] = -94.999266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1954343279, states[0] = -94.978222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1968181079, states[0] = -94.777321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1981696328, states[0] = -94.813678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1995216757, states[0] = -94.852246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2008681997, states[0] = -94.780046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2022124797, states[0] = -46.038442, states[40]= 0.000050
Saving checkpoint... 
Iteration: 2035881859, states[0] = -94.993421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2049689815, states[0] = -94.799655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2063524908, states[0] = 19.995703, states[40]= 0.007354
Saving checkpoint... 
Iteration: 2077128571, states[0] = -50.080129, states[40]= 0.000026
Saving checkpoint... 
Iteration: 2090744814, states[0] = -94.894859, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.893663
 - CaMKt in component CaMK (millimolar): 0.006804
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.576135
 - nass in component intracellular_ions (millimolar): 6.576194
 - ki in component intracellular_ions (millimolar): 145.403772
 - kss in component intracellular_ions (millimolar): 145.403753
 - cansr in component intracellular_ions (millimolar): 1.302930
 - cajsr in component intracellular_ions (millimolar): 1.265386
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003621
 - hf in component INa (dimensionless): 0.879859
 - hs in component INa (dimensionless): 0.879854
 - j in component INa (dimensionless): 0.879826
 - hsp in component INa (dimensionless): 0.725563
 - jp in component INa (dimensionless): 0.879807
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.710320
 - hLp in component INaL (dimensionless): 0.453607
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.623913
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.699250
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936901
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999892
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001569
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.330060
 - xs1 in component IKs (dimensionless): 0.237239
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997339
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
22:27:34 (4228): called boinc_finish(0)

</stderr_txt>
]]>