𝕏

Task 55750880

Name HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pueyo_APDR-conf_667_1
Workunit 26473657
Created 2 Jul 2024, 13:57:30 UTC
Sent 2 Jul 2024, 19:23:57 UTC
Report deadline 6 Jul 2024, 4:59:57 UTC
Received 4 Jul 2024, 2:42:17 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 214641
Run time 2 hours 48 min 29 sec
CPU time 2 hours 43 min 22 sec
Validate state Initial
Credit 0.00
Device peak FLOPS 3.78 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.14 MB
Peak swap size 6.22 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pueyo_APDR-conf_667.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pueyo_APDR-conf_667_1_r1807388877_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pueyo_APDR-conf_667_1_r1807388877_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 100.169846
     * GNaL_b in INaL: 0.005768
     * Gto_b in Ito: 0.083709
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031299
     * GKs_b in IKs: 0.001938
     * GK1_b in IK1: 0.161254
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 71.237265
     * GKb_b in IKb: 0.003780
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036075
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13397262, states[0] = -95.124916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26726003, states[0] = -94.956246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39838449, states[0] = -95.044458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 53113336, states[0] = -32.255192, states[40]= 0.000364
Saving checkpoint... 
Iteration: 66343230, states[0] = -95.025554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79493472, states[0] = -95.060947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 91902139, states[0] = -95.039458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 104415948, states[0] = -95.040787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118066457, states[0] = 5.050670, states[40]= 0.004696
Saving checkpoint... 
Iteration: 130990151, states[0] = -95.051566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 144277780, states[0] = -94.963273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 157735352, states[0] = -94.910729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 171149370, states[0] = -69.426610, states[40]= 0.000001
Saving checkpoint... 
Iteration: 183922686, states[0] = -95.037474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 197246386, states[0] = -94.925645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 209997180, states[0] = -95.050132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 223262520, states[0] = -94.945508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236575622, states[0] = 0.580914, states[40]= 0.004294
Saving checkpoint... 
Iteration: 249563029, states[0] = 6.653174, states[40]= 0.004777
Saving checkpoint... 
Iteration: 262657897, states[0] = -82.840209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275689234, states[0] = -94.823021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 288739774, states[0] = -94.916019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301881893, states[0] = -95.024910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314655585, states[0] = -78.861935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 327928193, states[0] = -95.038156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 341439838, states[0] = -95.040675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 355353796, states[0] = -95.013495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 369049970, states[0] = 11.939547, states[40]= 0.004960
Saving checkpoint... 
Iteration: 382604458, states[0] = -22.436366, states[40]= 0.000827
Saving checkpoint... 
Iteration: 395712936, states[0] = -94.871815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408886406, states[0] = -95.026388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 420568132, states[0] = 4.360806, states[40]= 0.004648
Saving checkpoint... 
Iteration: 433788258, states[0] = -94.971100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 446708064, states[0] = -94.862603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459129708, states[0] = -46.857089, states[40]= 0.000046
Saving checkpoint... 
Iteration: 472293287, states[0] = -94.975389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 485342754, states[0] = -95.008038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498023348, states[0] = 20.691088, states[40]= 0.007688
Saving checkpoint... 
Iteration: 511233220, states[0] = -94.906090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 523995068, states[0] = -95.049433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536606065, states[0] = -23.938858, states[40]= 0.000756
Saving checkpoint... 
Iteration: 549930997, states[0] = -95.038644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562893948, states[0] = -95.028756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 575699100, states[0] = -94.844738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 588782047, states[0] = -94.965362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 601690093, states[0] = -94.824954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 614620418, states[0] = -37.516026, states[40]= 0.000184
Saving checkpoint... 
Iteration: 627495247, states[0] = -95.049390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 640352811, states[0] = -95.012857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 653026952, states[0] = 19.781968, states[40]= 0.006607
Saving checkpoint... 
Iteration: 665343420, states[0] = -95.008267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678024612, states[0] = 20.387222, states[40]= 0.007227
Saving checkpoint... 
Iteration: 691072598, states[0] = 2.181952, states[40]= 0.004469
Saving checkpoint... 
Iteration: 703920776, states[0] = -95.036154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 716908151, states[0] = -95.032855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 729602988, states[0] = -21.061019, states[40]= 0.000900
Saving checkpoint... 
Iteration: 742935483, states[0] = -95.039506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755733442, states[0] = -94.906278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 766750188, states[0] = -94.929953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779975175, states[0] = -95.046592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 793147298, states[0] = -66.611617, states[40]= 0.000002
Saving checkpoint... 
Iteration: 806465201, states[0] = -95.045029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819612823, states[0] = -30.277094, states[40]= 0.000456
Saving checkpoint... 
Iteration: 832733617, states[0] = -94.906498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 845978010, states[0] = -95.046964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 859103352, states[0] = -21.401516, states[40]= 0.000881
Saving checkpoint... 
Iteration: 871912986, states[0] = -95.034065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 884639647, states[0] = -57.572780, states[40]= 0.000008
Saving checkpoint... 
Iteration: 897668427, states[0] = -93.789787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 910893518, states[0] = -95.028403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 923917175, states[0] = -95.035117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 936639050, states[0] = -56.908651, states[40]= 0.000009
Saving checkpoint... 
Iteration: 949290981, states[0] = -94.973141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 960498491, states[0] = -95.049574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 973046349, states[0] = 13.310081, states[40]= 0.005026
Saving checkpoint... 
Iteration: 986766298, states[0] = -94.949100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1000693715, states[0] = -94.833087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014360280, states[0] = -95.015980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1027833467, states[0] = -95.002716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041266486, states[0] = -94.949273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1054487591, states[0] = -95.048154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067913694, states[0] = -95.034129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081065882, states[0] = 5.394342, states[40]= 0.004713
Saving checkpoint... 
Iteration: 1093901001, states[0] = -95.030578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106817544, states[0] = -94.992996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119989819, states[0] = -95.048403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1132579211, states[0] = -1.479675, states[40]= 0.004008
Saving checkpoint... 
Iteration: 1145294177, states[0] = -94.975710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1158670956, states[0] = -94.323764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1171280744, states[0] = -94.963769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1184799248, states[0] = -94.979782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1198118288, states[0] = -35.463537, states[40]= 0.000244
Saving checkpoint... 
Iteration: 1210908682, states[0] = -95.032694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223538282, states[0] = 16.233017, states[40]= 0.005319
Saving checkpoint... 
Iteration: 1236690577, states[0] = -94.825739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250381053, states[0] = -95.024004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1264117775, states[0] = -34.972532, states[40]= 0.000261
Saving checkpoint... 
Iteration: 1276816869, states[0] = -94.992446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1289412496, states[0] = -95.033675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301397866, states[0] = -95.029509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1314886145, states[0] = -95.025734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328249935, states[0] = -94.929273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340410521, states[0] = -95.033115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1353688274, states[0] = -94.819734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1366875190, states[0] = -95.021786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1380396901, states[0] = -95.029165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1393406506, states[0] = -95.031976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406439990, states[0] = -95.040039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1419903294, states[0] = -95.031045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1433626947, states[0] = -44.003724, states[40]= 0.000071
Saving checkpoint... 
Iteration: 1446362390, states[0] = -95.016616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1459372212, states[0] = -95.020592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473192925, states[0] = -94.831038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1487037301, states[0] = 16.571558, states[40]= 0.005376
Saving checkpoint... 
Iteration: 1500221289, states[0] = -95.154362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1512535491, states[0] = -95.226330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1526300384, states[0] = -95.185735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1540084076, states[0] = -95.163162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1553891423, states[0] = -95.186561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1567631784, states[0] = -77.189876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1581128435, states[0] = -71.884472, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1594675672, states[0] = -95.161156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1608323122, states[0] = 19.997307, states[40]= 0.008978
Saving checkpoint... 
Iteration: 1621712007, states[0] = -95.237170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1635551798, states[0] = -95.291095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1649378786, states[0] = -95.316380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1663152599, states[0] = -95.292498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1676582561, states[0] = -95.180784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1690257498, states[0] = 3.570389, states[40]= 0.005211
Saving checkpoint... 
Iteration: 1703680658, states[0] = -95.318321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1717462397, states[0] = -95.302606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1731301586, states[0] = 47.535673, states[40]= 0.052378
Saving checkpoint... 
Iteration: 1744753251, states[0] = -95.293486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1758586475, states[0] = -95.322765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1772401746, states[0] = 46.625576, states[40]= 0.060018
Saving checkpoint... 
Iteration: 1786214331, states[0] = 22.611270, states[40]= 0.022412
Saving checkpoint... 
Iteration: 1800044319, states[0] = 11.947483, states[40]= 0.005804
Saving checkpoint... 
Iteration: 1813841653, states[0] = -95.051883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1827463528, states[0] = -95.075682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1840996922, states[0] = -95.070120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1854529027, states[0] = 19.039179, states[40]= 0.006203
Saving checkpoint... 
Iteration: 1868294955, states[0] = -94.985460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1881754716, states[0] = -94.941467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1895553693, states[0] = 10.419670, states[40]= 0.004912
Saving checkpoint... 
Iteration: 1909007976, states[0] = 24.206916, states[40]= 0.083709
Saving checkpoint... 
Iteration: 1922395475, states[0] = -95.030273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1936221395, states[0] = -94.887212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1950028738, states[0] = 19.275805, states[40]= 0.006265
Saving checkpoint... 
Iteration: 1963445880, states[0] = -95.041398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1977270133, states[0] = -94.952961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1991107854, states[0] = -25.626662, states[40]= 0.000678
Saving checkpoint... 
Iteration: 2004928502, states[0] = -95.037294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2018619491, states[0] = -36.626365, states[40]= 0.000209
Saving checkpoint... 
Iteration: 2032328549, states[0] = -94.999286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2045808991, states[0] = -94.986552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2059599342, states[0] = -17.650562, states[40]= 0.001151
Saving checkpoint... 
Iteration: 2072805041, states[0] = -94.983628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2085930286, states[0] = -95.037491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2098958245, states[0] = -95.043014, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.924875
 - CaMKt in component CaMK (millimolar): 0.006927
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.526517
 - nass in component intracellular_ions (millimolar): 6.526576
 - ki in component intracellular_ions (millimolar): 145.452404
 - kss in component intracellular_ions (millimolar): 145.452385
 - cansr in component intracellular_ions (millimolar): 1.306375
 - cajsr in component intracellular_ions (millimolar): 1.268276
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003610
 - hf in component INa (dimensionless): 0.880400
 - hs in component INa (dimensionless): 0.880395
 - j in component INa (dimensionless): 0.880366
 - hsp in component INa (dimensionless): 0.726582
 - jp in component INa (dimensionless): 0.880347
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.710068
 - hLp in component INaL (dimensionless): 0.451314
 - a in component Ito (dimensionless): 0.000622
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.619590
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.694108
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934059
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999881
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001580
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.332043
 - xs1 in component IKs (dimensionless): 0.244271
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997331
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
21:29:18 (9260): called boinc_finish(0)

</stderr_txt>
]]>


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