𝕏

Task 55750315

Name HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pueyo_APDR-conf_666_1
Workunit 26473375
Created 2 Jul 2024, 13:57:09 UTC
Sent 2 Jul 2024, 19:19:47 UTC
Report deadline 6 Jul 2024, 4:55:47 UTC
Received 4 Jul 2024, 19:09:03 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 240955
Run time 2 hours 44 min 50 sec
CPU time 1 hours 47 min 48 sec
Validate state Valid
Credit 67.28
Device peak FLOPS 4.40 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.59 MB
Peak swap size 6.23 MB
Peak disk usage 0.30 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pueyo_APDR-conf_666.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pueyo_APDR-conf_666_1_r1681758603_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pueyo_APDR-conf_666_1_r1681758603_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 103.599583
     * GNaL_b in INaL: 0.005861
     * Gto_b in Ito: 0.084044
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031544
     * GKs_b in IKs: 0.001895
     * GK1_b in IK1: 0.160215
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 69.231639
     * GKb_b in IKb: 0.003835
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032627
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 15852573, states[0] = -95.033026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33593384, states[0] = -14.700507, states[40]= 0.001517
Saving checkpoint... 
Iteration: 50516336, states[0] = 21.800041, states[40]= 0.014748
Saving checkpoint... 
Iteration: 65880395, states[0] = -94.986987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 81077785, states[0] = -1.299898, states[40]= 0.004069
Saving checkpoint... 
Iteration: 99806657, states[0] = -94.938897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117944361, states[0] = -94.993342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135792158, states[0] = -94.923842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 155232656, states[0] = -94.852601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 175275944, states[0] = -94.907385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194908403, states[0] = -94.981994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215163529, states[0] = -91.258195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235778913, states[0] = -94.909835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255694791, states[0] = -94.780914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275425173, states[0] = -94.986002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 294421230, states[0] = -94.985014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 312332058, states[0] = -94.950243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 333435891, states[0] = -94.988385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352578563, states[0] = -1.487749, states[40]= 0.004032
Saving checkpoint... 
Iteration: 370869244, states[0] = -94.968294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 391613621, states[0] = -31.687594, states[40]= 0.000396
Saving checkpoint... 
Iteration: 412633822, states[0] = -51.916666, states[40]= 0.000021
Saving checkpoint... 
Iteration: 434181426, states[0] = -94.735934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 455761228, states[0] = -94.890492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476541449, states[0] = 14.938869, states[40]= 0.005185
Saving checkpoint... 
Iteration: 497486559, states[0] = -94.997026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 518681753, states[0] = -94.738171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 531828133, states[0] = -94.947772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 541890294, states[0] = -94.975915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551932802, states[0] = -94.987558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 563038063, states[0] = 16.145529, states[40]= 0.005342
Saving checkpoint... 
Iteration: 574686414, states[0] = -94.759560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586539711, states[0] = 15.564128, states[40]= 0.005258
Saving checkpoint... 
Iteration: 597759850, states[0] = -94.888761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609042299, states[0] = 14.629028, states[40]= 0.005154
Saving checkpoint... 
Iteration: 620130967, states[0] = -48.876289, states[40]= 0.000034
Saving checkpoint... 
Iteration: 631617351, states[0] = -35.226241, states[40]= 0.000256
Saving checkpoint... 
Iteration: 643256669, states[0] = -94.884860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 654932861, states[0] = -94.987505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 666399201, states[0] = -94.978673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677680320, states[0] = -94.726657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 689549134, states[0] = 12.063013, states[40]= 0.004991
Saving checkpoint... 
Iteration: 702247816, states[0] = -94.873359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 712725526, states[0] = -94.839570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724959809, states[0] = -94.992777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 737209661, states[0] = -94.810875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 753911286, states[0] = -94.982107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 774595366, states[0] = -14.611692, states[40]= 0.001520
Saving checkpoint... 
Iteration: 785208416, states[0] = -94.808432, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pueyo_APDR-conf_666.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pueyo_APDR-conf_666_1_r1681758603_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pueyo_APDR-conf_666_1_r1681758603_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 103.599583
     * GNaL_b in INaL: 0.005861
     * Gto_b in Ito: 0.084044
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031544
     * GKs_b in IKs: 0.001895
     * GK1_b in IK1: 0.160215
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 69.231639
     * GKb_b in IKb: 0.003835
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032627
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 785208416
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.808432 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 797221723, states[0] = -94.832995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 808883192, states[0] = -94.973303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 820226154, states[0] = -94.840554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832109879, states[0] = -28.168568, states[40]= 0.000563
Saving checkpoint... 
Iteration: 842867575, states[0] = -94.967305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854652337, states[0] = -74.444671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 866827830, states[0] = -94.947372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878450092, states[0] = -94.990913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 891100588, states[0] = -19.478182, states[40]= 0.001008
Saving checkpoint... 
Iteration: 902324762, states[0] = -94.945468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913265967, states[0] = -94.895657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926735582, states[0] = -94.855588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940036054, states[0] = 16.837224, states[40]= 0.005466
Saving checkpoint... 
Iteration: 954577301, states[0] = -0.734731, states[40]= 0.004145
Saving checkpoint... 
Iteration: 967455539, states[0] = -94.991864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 979823552, states[0] = -94.944661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 996802206, states[0] = -94.929681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1017129982, states[0] = -47.839037, states[40]= 0.000040
Saving checkpoint... 
Iteration: 1032529186, states[0] = 19.018489, states[40]= 0.006184
Saving checkpoint... 
Iteration: 1046792033, states[0] = -94.921311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059974413, states[0] = -94.994928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1075171967, states[0] = -94.427735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089259067, states[0] = -94.887501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1101346517, states[0] = -94.957537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1113307541, states[0] = -94.933650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1128204388, states[0] = -94.800253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141683412, states[0] = -94.747325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154349376, states[0] = -94.958923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1166563490, states[0] = 6.195895, states[40]= 0.004781
Saving checkpoint... 
Iteration: 1178769983, states[0] = -94.899911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1190503055, states[0] = 36.766830, states[40]= 0.138920
Saving checkpoint... 
Iteration: 1202338127, states[0] = -94.953071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1214428840, states[0] = -94.986229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1226085790, states[0] = -6.414528, states[40]= 0.003094
Saving checkpoint... 
Iteration: 1238990754, states[0] = -94.997101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1251175863, states[0] = -94.647909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263891126, states[0] = -94.975723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276762840, states[0] = -94.891847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1288781846, states[0] = -94.911899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1300948146, states[0] = -94.990267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1313541778, states[0] = 14.819404, states[40]= 0.005173
Saving checkpoint... 
Iteration: 1336553084, states[0] = 10.524390, states[40]= 0.004936
Saving checkpoint... 
Iteration: 1353675043, states[0] = -94.619654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1366139844, states[0] = -58.499931, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1379021012, states[0] = 21.097497, states[40]= 0.008886
Saving checkpoint... 
Iteration: 1391841384, states[0] = -94.954699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1405547726, states[0] = 12.601404, states[40]= 0.005015
Saving checkpoint... 
Iteration: 1418461497, states[0] = -94.992619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1432180308, states[0] = -94.726042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1445449590, states[0] = -94.990451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1459152947, states[0] = -75.391264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1472769669, states[0] = -94.899380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1492851721, states[0] = -94.959840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1513440461, states[0] = -95.183519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1526406617, states[0] = 26.799904, states[40]= 0.103987
Saving checkpoint... 
Iteration: 1537701622, states[0] = -95.146592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1550726327, states[0] = 18.854715, states[40]= 0.007843
Saving checkpoint... 
Iteration: 1562749765, states[0] = 7.896826, states[40]= 0.005600
Saving checkpoint... 
Iteration: 1575005366, states[0] = 28.858109, states[40]= 0.125839
Saving checkpoint... 
Iteration: 1587488019, states[0] = -95.137438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1600784078, states[0] = -95.269503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1613131011, states[0] = 16.818892, states[40]= 0.006919
Saving checkpoint... 
Iteration: 1624881147, states[0] = -16.847841, states[40]= 0.001387
Saving checkpoint... 
Iteration: 1636783301, states[0] = -95.270987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1649102408, states[0] = 42.216911, states[40]= 0.090772
Saving checkpoint... 
Iteration: 1661620823, states[0] = -95.202326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1672878387, states[0] = -13.934496, states[40]= 0.001834
Saving checkpoint... 
Iteration: 1684444287, states[0] = -95.234196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1695555375, states[0] = -95.246575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1707640617, states[0] = 12.392927, states[40]= 0.006037
Saving checkpoint... 
Iteration: 1720501014, states[0] = 47.933930, states[40]= 0.023003
Saving checkpoint... 
Iteration: 1733464456, states[0] = -1.269425, states[40]= 0.004591
Saving checkpoint... 
Iteration: 1756027008, states[0] = -70.814571, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1773974502, states[0] = -9.923442, states[40]= 0.002661
Saving checkpoint... 
Iteration: 1786522826, states[0] = 19.966879, states[40]= 0.009086
Saving checkpoint... 
Iteration: 1799436569, states[0] = 14.317758, states[40]= 0.006321
Saving checkpoint... 
Iteration: 1812816906, states[0] = -94.986564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1831992713, states[0] = -95.025186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1853046535, states[0] = 12.816215, states[40]= 0.005042
Saving checkpoint... 
Iteration: 1864154693, states[0] = -79.561738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1874537783, states[0] = 16.134838, states[40]= 0.005357
Saving checkpoint... 
Iteration: 1884875487, states[0] = -94.975697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1895849889, states[0] = -94.962980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1907073286, states[0] = 1.412244, states[40]= 0.004419
Saving checkpoint... 
Iteration: 1918435506, states[0] = -94.989448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1929634658, states[0] = -52.932176, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1941996780, states[0] = -94.998469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1962167511, states[0] = -93.582194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1980589351, states[0] = -9.289439, states[40]= 0.002479
Saving checkpoint... 
Iteration: 1990921980, states[0] = -94.984297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2001847672, states[0] = -94.957671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2012908245, states[0] = -94.980536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2024980075, states[0] = -94.995180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2035917510, states[0] = -94.982943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2047793141, states[0] = -94.921606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2058834564, states[0] = -94.950515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2071736983, states[0] = -94.856939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2085068232, states[0] = 4.024310, states[40]= 0.004651
Saving checkpoint... 
Iteration: 2098684379, states[0] = -94.751044, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.873519
 - CaMKt in component CaMK (millimolar): 0.007021
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.612199
 - nass in component intracellular_ions (millimolar): 6.612259
 - ki in component intracellular_ions (millimolar): 145.364821
 - kss in component intracellular_ions (millimolar): 145.364802
 - cansr in component intracellular_ions (millimolar): 1.314179
 - cajsr in component intracellular_ions (millimolar): 1.276099
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003629
 - hf in component INa (dimensionless): 0.879508
 - hs in component INa (dimensionless): 0.879504
 - j in component INa (dimensionless): 0.879474
 - hsp in component INa (dimensionless): 0.724902
 - jp in component INa (dimensionless): 0.879454
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.708849
 - hLp in component INaL (dimensionless): 0.450192
 - a in component Ito (dimensionless): 0.000625
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.619951
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.694524
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934777
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999884
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001610
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.332817
 - xs1 in component IKs (dimensionless): 0.242643
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997345
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
19:18:41 (11764): called boinc_finish(0)

</stderr_txt>
]]>


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