𝕏

Task 55747180

Name HuVeMOp_20240702153647868011_ORdGradInc_k_26-CLVPET-conf_662_0
Workunit 26471808
Created 2 Jul 2024, 13:55:36 UTC
Sent 2 Jul 2024, 18:56:05 UTC
Report deadline 5 Jul 2024, 21:48:53 UTC
Received 3 Jul 2024, 3:27:25 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 230524
Run time 2 hours 33 min 11 sec
CPU time 2 hours 27 min 48 sec
Validate state Valid
Credit 50.51
Device peak FLOPS 3.86 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.48 MB
Peak swap size 2.35 GB
Peak disk usage 0.07 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-CLVPET-conf_662.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-CLVPET-conf_662_0_r1858330214_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-CLVPET-conf_662_0_r1858330214_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 101.883232
     * GNaL_b in INaL: 0.005538
     * Gto_b in Ito: 0.085939
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031540
     * GKs_b in IKs: 0.001886
     * GK1_b in IK1: 0.167282
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 70.563341
     * GKb_b in IKb: 0.003835
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033674
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11227831, states[0] = -94.718414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 22441738, states[0] = -94.921327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33443723, states[0] = -94.909225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 44666899, states[0] = -88.101090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 55959850, states[0] = -94.906255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67115596, states[0] = -27.698999, states[40]= 0.001089
Saving checkpoint... 
Iteration: 78392392, states[0] = -94.875458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 89627579, states[0] = -39.167725, states[40]= 0.000398
Saving checkpoint... 
Iteration: 100895871, states[0] = -94.876197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 112152515, states[0] = -65.802378, states[40]= 0.000007
Saving checkpoint... 
Iteration: 123369436, states[0] = -94.858639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 134623019, states[0] = -34.662057, states[40]= 0.000663
Saving checkpoint... 
Iteration: 145837421, states[0] = -94.830607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 157087694, states[0] = -1.636400, states[40]= 0.004338
Saving checkpoint... 
Iteration: 168281573, states[0] = -94.752969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 179517717, states[0] = 27.326692, states[40]= 0.004614
Saving checkpoint... 
Iteration: 190680720, states[0] = -94.283206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201869312, states[0] = -94.857702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213146868, states[0] = -59.191445, states[40]= 0.000021
Saving checkpoint... 
Iteration: 224389208, states[0] = -94.870733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235656472, states[0] = -70.889895, states[40]= 0.000003
Saving checkpoint... 
Iteration: 246913943, states[0] = -94.883675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 258150866, states[0] = -63.748487, states[40]= 0.000010
Saving checkpoint... 
Iteration: 269396064, states[0] = -94.874482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280639889, states[0] = -51.664885, states[40]= 0.000070
Saving checkpoint... 
Iteration: 291918229, states[0] = -94.885433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 303159977, states[0] = -76.092722, states[40]= 0.000001
Saving checkpoint... 
Iteration: 314438639, states[0] = -94.893536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325705938, states[0] = -94.535950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 336967526, states[0] = -94.902482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 348185608, states[0] = -94.416517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359488323, states[0] = -94.907409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370628981, states[0] = -40.457455, states[40]= 0.000339
Saving checkpoint... 
Iteration: 381941437, states[0] = -94.894264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 393253693, states[0] = -94.691676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404560363, states[0] = 13.246676, states[40]= 0.003632
Saving checkpoint... 
Iteration: 415859939, states[0] = -94.849615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 427199667, states[0] = -94.509084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 438442162, states[0] = -94.894294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449757517, states[0] = -94.700850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 461058270, states[0] = 14.140976, states[40]= 0.003465
Saving checkpoint... 
Iteration: 472374302, states[0] = -94.860126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 483690011, states[0] = -94.459125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494999344, states[0] = -94.909115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 506113443, states[0] = -25.471694, states[40]= 0.001165
Saving checkpoint... 
Iteration: 517207503, states[0] = -94.541531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527633281, states[0] = -44.785349, states[40]= 0.000191
Saving checkpoint... 
Iteration: 538603894, states[0] = -16.163453, states[40]= 0.001582
Saving checkpoint... 
Iteration: 549905080, states[0] = -94.878158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 561180500, states[0] = -94.270052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 572450486, states[0] = -94.896547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583737338, states[0] = -94.645946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594999158, states[0] = -94.908685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 606261279, states[0] = -94.709094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617501463, states[0] = 47.478084, states[40]= 0.322634
Saving checkpoint... 
Iteration: 628785483, states[0] = -94.758048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 640040752, states[0] = 20.982975, states[40]= 0.002135
Saving checkpoint... 
Iteration: 651275976, states[0] = -94.740236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 662411303, states[0] = -94.880775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673682224, states[0] = -94.341191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 684963797, states[0] = -94.900085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696310626, states[0] = -94.796696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 707552733, states[0] = 16.415990, states[40]= 0.003015
Saving checkpoint... 
Iteration: 718793120, states[0] = -94.770650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 730034751, states[0] = 23.083090, states[40]= 0.001799
Saving checkpoint... 
Iteration: 741317587, states[0] = -94.805558, states[40]= 0.000000
Saving checkpoint... 
Iteration: 752541068, states[0] = 20.868403, states[40]= 0.002155
Saving checkpoint... 
Iteration: 763638629, states[0] = -50.333335, states[40]= 0.000086
Saving checkpoint... 
Iteration: 774914150, states[0] = -94.881668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 786228522, states[0] = -94.617397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 797464432, states[0] = -94.899817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 808777348, states[0] = -94.742283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819883612, states[0] = -94.864914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 831153931, states[0] = -67.499885, states[40]= 0.000005
Saving checkpoint... 
Iteration: 842430546, states[0] = -94.888399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853736213, states[0] = -94.641470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 864915985, states[0] = -94.882154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 876211311, states[0] = -94.555179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887467510, states[0] = -94.900301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898757358, states[0] = -94.698676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 909988593, states[0] = -94.905293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921210216, states[0] = -94.550711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932441986, states[0] = -94.892280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 943626564, states[0] = -38.075116, states[40]= 0.000455
Saving checkpoint... 
Iteration: 954884456, states[0] = -94.864910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966141159, states[0] = -53.007449, states[40]= 0.000057
Saving checkpoint... 
Iteration: 977285853, states[0] = -94.757315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 988483580, states[0] = -94.903875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 999623803, states[0] = -35.392146, states[40]= 0.000615
Saving checkpoint... 
Iteration: 1010825657, states[0] = -94.814165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1022089043, states[0] = -2.631736, states[40]= 0.004197
Saving checkpoint... 
Iteration: 1033327876, states[0] = -94.816595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044605244, states[0] = -17.499071, states[40]= 0.001446
Saving checkpoint... 
Iteration: 1055848121, states[0] = -94.836976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067130968, states[0] = -42.438714, states[40]= 0.000262
Saving checkpoint... 
Iteration: 1078383040, states[0] = -94.863529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089624307, states[0] = -35.879219, states[40]= 0.000584
Saving checkpoint... 
Iteration: 1100830390, states[0] = -94.819111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112057522, states[0] = 14.456671, states[40]= 0.003405
Saving checkpoint... 
Iteration: 1123330691, states[0] = -94.819351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1134440417, states[0] = -94.890930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1145570135, states[0] = 8.746993, states[40]= 0.004315
Saving checkpoint... 
Iteration: 1156827802, states[0] = -94.816022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1168053930, states[0] = 15.935163, states[40]= 0.003112
Saving checkpoint... 
Iteration: 1179301091, states[0] = -94.781249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1190569711, states[0] = 8.955795, states[40]= 0.004291
Saving checkpoint... 
Iteration: 1201742789, states[0] = -94.659364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1213006801, states[0] = 28.453133, states[40]= 0.142231
Saving checkpoint... 
Iteration: 1224292368, states[0] = -94.767412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1235535574, states[0] = 22.805961, states[40]= 0.001840
Saving checkpoint... 
Iteration: 1246762991, states[0] = -94.710456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258037742, states[0] = 22.057396, states[40]= 0.001956
Saving checkpoint... 
Iteration: 1269261197, states[0] = -94.706261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1280509383, states[0] = 27.664674, states[40]= 0.060035
Saving checkpoint... 
Iteration: 1291642566, states[0] = -54.506648, states[40]= 0.000045
Saving checkpoint... 
Iteration: 1302822922, states[0] = -94.809819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1314068501, states[0] = 9.544094, states[40]= 0.004218
Saving checkpoint... 
Iteration: 1325329331, states[0] = -94.817057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336515502, states[0] = 27.523851, states[40]= 0.008459
Saving checkpoint... 
Iteration: 1347770005, states[0] = -94.725346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1358997143, states[0] = -94.905276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1370241562, states[0] = -94.655195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1381500423, states[0] = -41.753861, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1392724247, states[0] = -94.600569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1403979493, states[0] = -94.901286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415279334, states[0] = -94.743668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1426414352, states[0] = -94.879185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437663071, states[0] = -81.181058, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1448738531, states[0] = -94.646045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1459980701, states[0] = -94.901349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471215847, states[0] = -94.570102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482473681, states[0] = -94.899556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493757720, states[0] = -94.697174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1504978512, states[0] = 22.855575, states[40]= 0.005242
Saving checkpoint... 
Iteration: 1515973669, states[0] = -94.989165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1526954964, states[0] = -94.496540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1537843802, states[0] = -3.726979, states[40]= 0.003728
Saving checkpoint... 
Iteration: 1548884453, states[0] = -94.790278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1559793758, states[0] = -94.705761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1570729929, states[0] = -94.690762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1581689146, states[0] = -89.269002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1592644161, states[0] = -94.586600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1603445541, states[0] = -94.578808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1614374067, states[0] = -94.561705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1625293964, states[0] = -94.284072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1636238502, states[0] = -94.490100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1647148392, states[0] = -94.473207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1658087948, states[0] = -94.474172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1669000944, states[0] = -94.470925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1679909981, states[0] = -94.460305, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -94.335830
 - CaMKt in component CaMK (millimolar): 0.001127
 - cass in component intracellular_ions (millimolar): 0.000087
 - nai in component intracellular_ions (millimolar): 6.373773
 - nass in component intracellular_ions (millimolar): 6.373860
 - ki in component intracellular_ions (millimolar): 145.522366
 - kss in component intracellular_ions (millimolar): 145.522354
 - cansr in component intracellular_ions (millimolar): 1.568044
 - cajsr in component intracellular_ions (millimolar): 1.568081
 - cai in component intracellular_ions (millimolar): 0.000090
 - m in component INa (dimensionless): 0.003831
 - hf in component INa (dimensionless): 0.869826
 - hs in component INa (dimensionless): 0.869826
 - j in component INa (dimensionless): 0.869827
 - hsp in component INa (dimensionless): 0.706965
 - jp in component INa (dimensionless): 0.869828
 - mL in component INaL (dimensionless): 0.000055
 - hL in component INaL (dimensionless): 0.713991
 - hLp in component INaL (dimensionless): 0.521631
 - a in component Ito (dimensionless): 0.000648
 - iF in component Ito (dimensionless): 0.999856
 - iS in component Ito (dimensionless): 0.997762
 - ap in component Ito (dimensionless): 0.000330
 - iFp in component Ito (dimensionless): 0.999856
 - iSp in component Ito (dimensionless): 0.999259
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998879
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003011
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001772
 - xs1 in component IKs (dimensionless): 0.022622
 - xs2 in component IKs (dimensionless): 0.000094
 - xk1 in component IK1 (dimensionless): 0.997482
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
19:22:11 (17064): called boinc_finish(0)

</stderr_txt>
]]>


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