𝕏

Task 55746959

Name HuVeMOp_20240702153647868011_ORdGradInc_k_26-Schmidt_2000-conf_961_1
Workunit 26471697
Created 2 Jul 2024, 13:55:31 UTC
Sent 2 Jul 2024, 18:56:05 UTC
Report deadline 5 Jul 2024, 18:56:05 UTC
Received 2 Jul 2024, 23:36:11 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 230524
Run time 2 hours 18 min 49 sec
CPU time 2 hours 14 min 6 sec
Validate state Valid
Credit 48.00
Device peak FLOPS 3.86 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.73 MB
Peak swap size 2.35 GB
Peak disk usage 0.64 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Schmidt_2000-conf_961.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Schmidt_2000-conf_961_1_r1921773559_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Schmidt_2000-conf_961_1_r1921773559_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 106.401310
     * GNaL_b in INaL: 0.005954
     * Gto_b in Ito: 0.082954
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032263
     * GKs_b in IKs: 0.001896
     * GK1_b in IK1: 0.160137
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 71.257149
     * GKb_b in IKb: 0.003834
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032743
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 11020146, states[0] = 29.793056, states[40]= 0.001473
Saving checkpoint... 
Iteration: 22121587, states[0] = -22.859219, states[40]= 0.000414
Saving checkpoint... 
Iteration: 33263937, states[0] = -83.769779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 44429015, states[0] = -84.109917, states[40]= 0.000001
Saving checkpoint... 
Iteration: 55590256, states[0] = -84.164634, states[40]= 0.000001
Saving checkpoint... 
Iteration: 66575029, states[0] = -84.150241, states[40]= 0.000001
Saving checkpoint... 
Iteration: 77701894, states[0] = -84.154144, states[40]= 0.000001
Saving checkpoint... 
Iteration: 88846405, states[0] = -84.145550, states[40]= 0.000001
Saving checkpoint... 
Iteration: 100005306, states[0] = 29.325215, states[40]= 0.286979
Saving checkpoint... 
Iteration: 111148504, states[0] = -43.115884, states[40]= 0.000128
Saving checkpoint... 
Iteration: 122285595, states[0] = -83.773457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133416827, states[0] = -84.043176, states[40]= 0.000001
Saving checkpoint... 
Iteration: 144545073, states[0] = -84.115020, states[40]= 0.000001
Saving checkpoint... 
Iteration: 155706102, states[0] = -84.133503, states[40]= 0.000001
Saving checkpoint... 
Iteration: 166843843, states[0] = -84.130248, states[40]= 0.000001
Saving checkpoint... 
Iteration: 177980728, states[0] = -84.122416, states[40]= 0.000001
Saving checkpoint... 
Iteration: 189130416, states[0] = -26.405312, states[40]= 0.000503
Saving checkpoint... 
Iteration: 200272778, states[0] = -83.715527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 211399902, states[0] = -84.019921, states[40]= 0.000001
Saving checkpoint... 
Iteration: 222409634, states[0] = -84.030686, states[40]= 0.000001
Saving checkpoint... 
Iteration: 233573611, states[0] = -84.118075, states[40]= 0.000001
Saving checkpoint... 
Iteration: 244439384, states[0] = -84.058135, states[40]= 0.000001
Saving checkpoint... 
Iteration: 255132621, states[0] = -28.357280, states[40]= 0.000490
Saving checkpoint... 
Iteration: 265925947, states[0] = -84.123700, states[40]= 0.000001
Saving checkpoint... 
Iteration: 276680863, states[0] = -84.129473, states[40]= 0.000001
Saving checkpoint... 
Iteration: 287499593, states[0] = -84.094376, states[40]= 0.000001
Saving checkpoint... 
Iteration: 298254128, states[0] = -83.627132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 309017104, states[0] = 31.148625, states[40]= 0.004583
Saving checkpoint... 
Iteration: 319788620, states[0] = -84.129362, states[40]= 0.000001
Saving checkpoint... 
Iteration: 330601930, states[0] = -84.122160, states[40]= 0.000001
Saving checkpoint... 
Iteration: 341368831, states[0] = -83.975575, states[40]= 0.000001
Saving checkpoint... 
Iteration: 352170969, states[0] = -63.959397, states[40]= 0.000006
Saving checkpoint... 
Iteration: 362949014, states[0] = -84.121717, states[40]= 0.000001
Saving checkpoint... 
Iteration: 373639142, states[0] = -84.126200, states[40]= 0.000001
Saving checkpoint... 
Iteration: 384222434, states[0] = -83.444805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395035545, states[0] = 27.278047, states[40]= 0.000029
Saving checkpoint... 
Iteration: 405827115, states[0] = -84.127564, states[40]= 0.000001
Saving checkpoint... 
Iteration: 416584515, states[0] = -84.118804, states[40]= 0.000001
Saving checkpoint... 
Iteration: 427384472, states[0] = -83.998365, states[40]= 0.000001
Saving checkpoint... 
Iteration: 438177704, states[0] = -71.366983, states[40]= 0.000002
Saving checkpoint... 
Iteration: 448965853, states[0] = -84.120242, states[40]= 0.000001
Saving checkpoint... 
Iteration: 459794662, states[0] = -84.128359, states[40]= 0.000001
Saving checkpoint... 
Iteration: 470599666, states[0] = -84.120996, states[40]= 0.000001
Saving checkpoint... 
Iteration: 481425757, states[0] = -84.044797, states[40]= 0.000001
Saving checkpoint... 
Iteration: 492234510, states[0] = -83.518055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 503029070, states[0] = 29.169959, states[40]= 0.000084
Saving checkpoint... 
Iteration: 513670334, states[0] = -84.127529, states[40]= 0.000001
Saving checkpoint... 
Iteration: 524361463, states[0] = -83.962190, states[40]= 0.000001
Saving checkpoint... 
Iteration: 535072265, states[0] = 13.045601, states[40]= 0.000229
Saving checkpoint... 
Iteration: 545835382, states[0] = -84.126425, states[40]= 0.000001
Saving checkpoint... 
Iteration: 556569312, states[0] = -84.114993, states[40]= 0.000001
Saving checkpoint... 
Iteration: 567206720, states[0] = -83.308669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 577984464, states[0] = -84.118409, states[40]= 0.000001
Saving checkpoint... 
Iteration: 588738174, states[0] = -84.128567, states[40]= 0.000001
Saving checkpoint... 
Iteration: 599480321, states[0] = -84.083026, states[40]= 0.000001
Saving checkpoint... 
Iteration: 610193834, states[0] = -82.496973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620923741, states[0] = -84.121644, states[40]= 0.000001
Saving checkpoint... 
Iteration: 631661859, states[0] = -84.126380, states[40]= 0.000001
Saving checkpoint... 
Iteration: 642396729, states[0] = -84.013019, states[40]= 0.000001
Saving checkpoint... 
Iteration: 642695037, states[0] = -84.127752, states[40]= 0.000001
Saving checkpoint... 
Iteration: 653581230, states[0] = -84.116833, states[40]= 0.000001
Saving checkpoint... 
Iteration: 664771686, states[0] = -84.127741, states[40]= 0.000001
Saving checkpoint... 
Iteration: 676003361, states[0] = 31.709485, states[40]= 0.559405
Saving checkpoint... 
Iteration: 687211682, states[0] = -83.365259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 698367740, states[0] = -83.971716, states[40]= 0.000001
Saving checkpoint... 
Iteration: 709518225, states[0] = -84.099456, states[40]= 0.000001
Saving checkpoint... 
Iteration: 720694168, states[0] = -84.127279, states[40]= 0.000001
Saving checkpoint... 
Iteration: 731878155, states[0] = -84.123404, states[40]= 0.000001
Saving checkpoint... 
Iteration: 743062714, states[0] = 17.077489, states[40]= 0.000129
Saving checkpoint... 
Iteration: 754200485, states[0] = -83.140406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 765367533, states[0] = -83.970990, states[40]= 0.000001
Saving checkpoint... 
Iteration: 776539025, states[0] = -84.106002, states[40]= 0.000001
Saving checkpoint... 
Iteration: 787735796, states[0] = -84.127427, states[40]= 0.000001
Saving checkpoint... 
Iteration: 798918874, states[0] = -84.120887, states[40]= 0.000001
Saving checkpoint... 
Iteration: 809972132, states[0] = -84.117797, states[40]= 0.000001
Saving checkpoint... 
Iteration: 820970113, states[0] = -84.117851, states[40]= 0.000001
Saving checkpoint... 
Iteration: 832164840, states[0] = -57.772272, states[40]= 0.000016
Saving checkpoint... 
Iteration: 843376672, states[0] = -83.984777, states[40]= 0.000001
Saving checkpoint... 
Iteration: 854575633, states[0] = -84.114590, states[40]= 0.000001
Saving checkpoint... 
Iteration: 865699666, states[0] = -84.126590, states[40]= 0.000001
Saving checkpoint... 
Iteration: 876878099, states[0] = -84.122573, states[40]= 0.000001
Saving checkpoint... 
Iteration: 888028259, states[0] = 29.379298, states[40]= 0.000106
Saving checkpoint... 
Iteration: 899114651, states[0] = -11.616333, states[40]= 0.000707
Saving checkpoint... 
Iteration: 910279340, states[0] = -83.737581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921398425, states[0] = -84.013456, states[40]= 0.000001
Saving checkpoint... 
Iteration: 932551974, states[0] = -84.108717, states[40]= 0.000001
Saving checkpoint... 
Iteration: 943721074, states[0] = -84.126481, states[40]= 0.000001
Saving checkpoint... 
Iteration: 954886135, states[0] = -84.121720, states[40]= 0.000001
Saving checkpoint... 
Iteration: 965894833, states[0] = -84.121210, states[40]= 0.000001
Saving checkpoint... 
Iteration: 977094865, states[0] = 2.465354, states[40]= 0.000720
Saving checkpoint... 
Iteration: 988249646, states[0] = -83.599746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 999405472, states[0] = -84.021180, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1010541909, states[0] = -84.105503, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1021675551, states[0] = -84.124861, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1032812470, states[0] = -84.124494, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1043863677, states[0] = -84.122309, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1054995248, states[0] = -84.115025, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1066134160, states[0] = -29.730645, states[40]= 0.000468
Saving checkpoint... 
Iteration: 1077265897, states[0] = -83.679129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1088439538, states[0] = -84.053143, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1099526869, states[0] = -84.100272, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1110727311, states[0] = -84.125559, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1121699839, states[0] = -84.125122, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1132822530, states[0] = -84.123554, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1144017293, states[0] = 31.145367, states[40]= 0.004289
Saving checkpoint... 
Iteration: 1155187609, states[0] = -80.366119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1166301500, states[0] = -83.815424, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1177474630, states[0] = -84.076531, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1188618869, states[0] = -84.119432, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1199778695, states[0] = -84.124515, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1210718013, states[0] = -84.124918, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1221867458, states[0] = -84.121105, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1232889600, states[0] = -84.119944, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1244049652, states[0] = 22.278333, states[40]= 0.000056
Saving checkpoint... 
Iteration: 1255049923, states[0] = 22.174785, states[40]= 0.000057
Saving checkpoint... 
Iteration: 1266201534, states[0] = -83.179781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277194290, states[0] = -82.568309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1288312284, states[0] = -83.847289, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1299449009, states[0] = -84.059199, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1310616349, states[0] = -84.118429, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1321780794, states[0] = -84.123765, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1332968468, states[0] = -84.114999, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1344143577, states[0] = -38.209568, states[40]= 0.000234
Saving checkpoint... 
Iteration: 1355316408, states[0] = -83.858433, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1366483165, states[0] = -84.080118, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1377674971, states[0] = -84.122787, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1388794484, states[0] = -84.123020, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1399993240, states[0] = -84.113157, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1411103931, states[0] = -2.937786, states[40]= 0.000914
Saving checkpoint... 
Iteration: 1422265700, states[0] = -83.676178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1433329263, states[0] = -83.890963, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1444507799, states[0] = -84.091152, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1455707844, states[0] = -84.123367, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1466908149, states[0] = -84.117623, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1478076571, states[0] = 11.170338, states[40]= 0.000293
Saving checkpoint... 
Iteration: 1489203062, states[0] = -83.227270, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -83.988119
 - CaMKt in component CaMK (millimolar): 0.005162
 - cass in component intracellular_ions (millimolar): 0.000089
 - nai in component intracellular_ions (millimolar): 6.307842
 - nass in component intracellular_ions (millimolar): 6.307949
 - ki in component intracellular_ions (millimolar): 145.555339
 - kss in component intracellular_ions (millimolar): 145.555323
 - cansr in component intracellular_ions (millimolar): 1.689541
 - cajsr in component intracellular_ions (millimolar): 1.688883
 - cai in component intracellular_ions (millimolar): 0.000092
 - m in component INa (dimensionless): 0.010853
 - hf in component INa (dimensionless): 0.549630
 - hs in component INa (dimensionless): 0.549636
 - j in component INa (dimensionless): 0.549664
 - hsp in component INa (dimensionless): 0.305874
 - jp in component INa (dimensionless): 0.549679
 - mL in component INaL (dimensionless): 0.000394
 - hL in component INaL (dimensionless): 0.385322
 - hLp in component INaL (dimensionless): 0.207794
 - a in component Ito (dimensionless): 0.001301
 - iF in component Ito (dimensionless): 0.999120
 - iS in component Ito (dimensionless): 0.846114
 - ap in component Ito (dimensionless): 0.000663
 - iFp in component Ito (dimensionless): 0.999120
 - iSp in component Ito (dimensionless): 0.875005
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.973456
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003216
 - xrf in component IKr (dimensionless): 0.000014
 - xrs in component IKr (dimensionless): 0.210873
 - xs1 in component IKs (dimensionless): 0.132647
 - xs2 in component IKs (dimensionless): 0.000298
 - xk1 in component IK1 (dimensionless): 0.996921
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
15:30:52 (15050): called boinc_finish(0)

</stderr_txt>
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