𝕏

Task 55746811

Name HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_MID_5000-conf_561_1
Workunit 26471623
Created 2 Jul 2024, 13:55:26 UTC
Sent 2 Jul 2024, 18:56:05 UTC
Report deadline 5 Jul 2024, 18:56:05 UTC
Received 3 Jul 2024, 0:54:33 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 230524
Run time 2 hours 18 min 20 sec
CPU time 2 hours 13 min 34 sec
Validate state Valid
Credit 44.46
Device peak FLOPS 3.86 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.43 MB
Peak swap size 2.35 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_MID_5000-conf_561.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_MID_5000-conf_561_1_r1661670018_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_MID_5000-conf_561_1_r1661670018_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 106.826930
     * GNaL_b in INaL: 0.006128
     * Gto_b in Ito: 0.081286
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031832
     * GKs_b in IKs: 0.001971
     * GK1_b in IK1: 0.160642
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 70.881832
     * GKb_b in IKb: 0.003814
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035021
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 10799881, states[0] = -94.205244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 21462686, states[0] = -94.170529, states[40]= 0.000001
Saving checkpoint... 
Iteration: 32281592, states[0] = -94.168241, states[40]= 0.000001
Saving checkpoint... 
Iteration: 43051508, states[0] = -94.157640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 53863748, states[0] = -94.202901, states[40]= 0.000001
Saving checkpoint... 
Iteration: 64665648, states[0] = -94.195072, states[40]= 0.000001
Saving checkpoint... 
Iteration: 75408280, states[0] = -94.027616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 86218727, states[0] = -94.224150, states[40]= 0.000001
Saving checkpoint... 
Iteration: 97046062, states[0] = -94.210218, states[40]= 0.000001
Saving checkpoint... 
Iteration: 107861412, states[0] = -93.927450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118664935, states[0] = -94.234186, states[40]= 0.000001
Saving checkpoint... 
Iteration: 129484756, states[0] = -94.217500, states[40]= 0.000001
Saving checkpoint... 
Iteration: 140273422, states[0] = -71.354884, states[40]= 0.000020
Saving checkpoint... 
Iteration: 150909887, states[0] = -94.245151, states[40]= 0.000001
Saving checkpoint... 
Iteration: 161712569, states[0] = -94.224463, states[40]= 0.000001
Saving checkpoint... 
Iteration: 172551288, states[0] = 32.060024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183323596, states[0] = -94.247100, states[40]= 0.000001
Saving checkpoint... 
Iteration: 194149545, states[0] = -94.226766, states[40]= 0.000001
Saving checkpoint... 
Iteration: 204982379, states[0] = -94.217260, states[40]= 0.000001
Saving checkpoint... 
Iteration: 215780816, states[0] = -94.246760, states[40]= 0.000001
Saving checkpoint... 
Iteration: 226613925, states[0] = -94.227823, states[40]= 0.000001
Saving checkpoint... 
Iteration: 237454030, states[0] = -94.217620, states[40]= 0.000001
Saving checkpoint... 
Iteration: 248300406, states[0] = -94.247349, states[40]= 0.000001
Saving checkpoint... 
Iteration: 259140151, states[0] = -94.227285, states[40]= 0.000001
Saving checkpoint... 
Iteration: 269990901, states[0] = -94.217346, states[40]= 0.000001
Saving checkpoint... 
Iteration: 280723035, states[0] = -94.243649, states[40]= 0.000001
Saving checkpoint... 
Iteration: 291469941, states[0] = -94.230938, states[40]= 0.000001
Saving checkpoint... 
Iteration: 302217444, states[0] = -94.219096, states[40]= 0.000001
Saving checkpoint... 
Iteration: 312997903, states[0] = -94.170884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 323729579, states[0] = -94.237502, states[40]= 0.000001
Saving checkpoint... 
Iteration: 334422619, states[0] = -94.222133, states[40]= 0.000001
Saving checkpoint... 
Iteration: 345154394, states[0] = -4.546142, states[40]= 0.000453
Saving checkpoint... 
Iteration: 355911902, states[0] = -94.246575, states[40]= 0.000001
Saving checkpoint... 
Iteration: 366664216, states[0] = -94.226120, states[40]= 0.000001
Saving checkpoint... 
Iteration: 377417497, states[0] = -94.217044, states[40]= 0.000001
Saving checkpoint... 
Iteration: 388177008, states[0] = -94.238046, states[40]= 0.000001
Saving checkpoint... 
Iteration: 398970301, states[0] = -94.230133, states[40]= 0.000001
Saving checkpoint... 
Iteration: 409684075, states[0] = -94.218580, states[40]= 0.000001
Saving checkpoint... 
Iteration: 420883327, states[0] = -94.246457, states[40]= 0.000001
Saving checkpoint... 
Iteration: 431905322, states[0] = -94.221601, states[40]= 0.000001
Saving checkpoint... 
Iteration: 443104702, states[0] = -94.222949, states[40]= 0.000001
Saving checkpoint... 
Iteration: 454340267, states[0] = -94.222370, states[40]= 0.000001
Saving checkpoint... 
Iteration: 465543540, states[0] = -94.198989, states[40]= 0.000001
Saving checkpoint... 
Iteration: 476727902, states[0] = -94.224046, states[40]= 0.000001
Saving checkpoint... 
Iteration: 487855838, states[0] = -93.923956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499089234, states[0] = -94.226577, states[40]= 0.000001
Saving checkpoint... 
Iteration: 510312984, states[0] = -93.748747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521551533, states[0] = -94.227219, states[40]= 0.000001
Saving checkpoint... 
Iteration: 532654368, states[0] = -4.533659, states[40]= 0.000452
Saving checkpoint... 
Iteration: 543844029, states[0] = -94.232312, states[40]= 0.000001
Saving checkpoint... 
Iteration: 555055880, states[0] = 30.926143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566245034, states[0] = -94.235076, states[40]= 0.000001
Saving checkpoint... 
Iteration: 577453923, states[0] = -94.215194, states[40]= 0.000001
Saving checkpoint... 
Iteration: 588533709, states[0] = -94.241627, states[40]= 0.000001
Saving checkpoint... 
Iteration: 599792814, states[0] = -94.216105, states[40]= 0.000001
Saving checkpoint... 
Iteration: 611029368, states[0] = -94.241575, states[40]= 0.000001
Saving checkpoint... 
Iteration: 622237360, states[0] = -94.216372, states[40]= 0.000001
Saving checkpoint... 
Iteration: 633457706, states[0] = -94.243368, states[40]= 0.000001
Saving checkpoint... 
Iteration: 644686522, states[0] = -94.216637, states[40]= 0.000001
Saving checkpoint... 
Iteration: 645141610, states[0] = 0.921539, states[40]= 0.000238
Saving checkpoint... 
Iteration: 656249970, states[0] = -94.234187, states[40]= 0.000001
Saving checkpoint... 
Iteration: 667476679, states[0] = -94.214325, states[40]= 0.000001
Saving checkpoint... 
Iteration: 678673973, states[0] = -94.236406, states[40]= 0.000001
Saving checkpoint... 
Iteration: 689831918, states[0] = -94.215073, states[40]= 0.000001
Saving checkpoint... 
Iteration: 701012563, states[0] = -94.241337, states[40]= 0.000001
Saving checkpoint... 
Iteration: 712041171, states[0] = -94.217584, states[40]= 0.000001
Saving checkpoint... 
Iteration: 723244673, states[0] = -94.241619, states[40]= 0.000001
Saving checkpoint... 
Iteration: 734378576, states[0] = -94.219507, states[40]= 0.000001
Saving checkpoint... 
Iteration: 745577756, states[0] = -94.211683, states[40]= 0.000001
Saving checkpoint... 
Iteration: 756770921, states[0] = -94.221009, states[40]= 0.000001
Saving checkpoint... 
Iteration: 768011283, states[0] = -94.177145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779206409, states[0] = -94.221960, states[40]= 0.000001
Saving checkpoint... 
Iteration: 790451276, states[0] = -94.120464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 801671412, states[0] = -94.222434, states[40]= 0.000001
Saving checkpoint... 
Iteration: 812814637, states[0] = -93.754333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824055666, states[0] = -94.224652, states[40]= 0.000001
Saving checkpoint... 
Iteration: 835262250, states[0] = -61.561708, states[40]= 0.000091
Saving checkpoint... 
Iteration: 846459782, states[0] = -94.226739, states[40]= 0.000001
Saving checkpoint... 
Iteration: 857679154, states[0] = -17.590988, states[40]= 0.001319
Saving checkpoint... 
Iteration: 868856128, states[0] = -94.229312, states[40]= 0.000001
Saving checkpoint... 
Iteration: 880113043, states[0] = 11.428973, states[40]= 0.000027
Saving checkpoint... 
Iteration: 891296532, states[0] = -94.230853, states[40]= 0.000001
Saving checkpoint... 
Iteration: 902331033, states[0] = -94.213340, states[40]= 0.000001
Saving checkpoint... 
Iteration: 913567513, states[0] = -94.237921, states[40]= 0.000001
Saving checkpoint... 
Iteration: 924788784, states[0] = -94.213475, states[40]= 0.000001
Saving checkpoint... 
Iteration: 936028063, states[0] = -94.238958, states[40]= 0.000001
Saving checkpoint... 
Iteration: 947284196, states[0] = -94.213326, states[40]= 0.000001
Saving checkpoint... 
Iteration: 958488267, states[0] = -94.239922, states[40]= 0.000001
Saving checkpoint... 
Iteration: 969476810, states[0] = -94.216252, states[40]= 0.000001
Saving checkpoint... 
Iteration: 980699313, states[0] = -94.235880, states[40]= 0.000001
Saving checkpoint... 
Iteration: 991900703, states[0] = -94.217083, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1003082174, states[0] = -94.211177, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1014277128, states[0] = -94.218797, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1025487537, states[0] = -94.156462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1036624700, states[0] = -94.221437, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1047841751, states[0] = -93.869599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058893205, states[0] = -94.226735, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1070076456, states[0] = 24.594741, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1081324367, states[0] = -94.228481, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1092435229, states[0] = -94.211088, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1103514502, states[0] = -94.237992, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1114581708, states[0] = -94.213837, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1125810420, states[0] = -94.240625, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1137046453, states[0] = -94.214044, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1148237809, states[0] = -94.237726, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1159425499, states[0] = -94.215368, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1170650435, states[0] = -94.227484, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1181873654, states[0] = -94.215915, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1193134855, states[0] = -94.224255, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1204348857, states[0] = -94.216100, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1215469337, states[0] = -94.137515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1226669830, states[0] = -94.218985, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1237906790, states[0] = -94.047345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249127722, states[0] = -94.219636, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1260326502, states[0] = -93.805534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1271525112, states[0] = -94.221685, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1282701954, states[0] = -24.930584, states[40]= 0.005626
Saving checkpoint... 
Iteration: 1293910187, states[0] = -94.224358, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1305112799, states[0] = 11.519550, states[40]= 0.000027
Saving checkpoint... 
Iteration: 1316196042, states[0] = -94.230486, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1327411648, states[0] = -94.209309, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1338629884, states[0] = -94.232438, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1349820812, states[0] = -94.209749, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1361069986, states[0] = -94.234184, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1372026687, states[0] = -94.212348, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1383265648, states[0] = -94.237272, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1394512364, states[0] = -94.212334, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1405726518, states[0] = -94.234838, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1416960845, states[0] = -94.212792, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1428179593, states[0] = -94.229896, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1439405765, states[0] = -94.213348, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1450602962, states[0] = -94.214203, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1461851997, states[0] = -94.213945, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1473053150, states[0] = -94.195443, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1483824034, states[0] = -94.225198, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1495022405, states[0] = 33.785853, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.083352
 - CaMKt in component CaMK (millimolar): 0.001764
 - cass in component intracellular_ions (millimolar): 0.000095
 - nai in component intracellular_ions (millimolar): 7.732373
 - nass in component intracellular_ions (millimolar): 7.732523
 - ki in component intracellular_ions (millimolar): 144.091798
 - kss in component intracellular_ions (millimolar): 144.091784
 - cansr in component intracellular_ions (millimolar): 1.778869
 - cajsr in component intracellular_ions (millimolar): 1.780279
 - cai in component intracellular_ions (millimolar): 0.000100
 - m in component INa (dimensionless): 0.003930
 - hf in component INa (dimensionless): 0.865056
 - hs in component INa (dimensionless): 0.865056
 - j in component INa (dimensionless): 0.865057
 - hsp in component INa (dimensionless): 0.698298
 - jp in component INa (dimensionless): 0.865058
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.707060
 - hLp in component INaL (dimensionless): 0.513162
 - a in component Ito (dimensionless): 0.000659
 - iF in component Ito (dimensionless): 0.999850
 - iS in component Ito (dimensionless): 0.997179
 - ap in component Ito (dimensionless): 0.000336
 - iFp in component Ito (dimensionless): 0.999850
 - iSp in component Ito (dimensionless): 0.999024
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998015
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004236
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.002460
 - xs1 in component IKs (dimensionless): 0.032810
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997544
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
16:48:58 (15231): called boinc_finish(0)

</stderr_txt>
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