𝕏

Task 55746788

Name HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_MID_4000-conf_461_0
Workunit 26471612
Created 2 Jul 2024, 13:55:26 UTC
Sent 2 Jul 2024, 18:56:05 UTC
Report deadline 5 Jul 2024, 18:56:05 UTC
Received 3 Jul 2024, 5:44:10 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 230524
Run time 2 hours 16 min 28 sec
CPU time 2 hours 11 min 50 sec
Validate state Valid
Credit 43.16
Device peak FLOPS 3.86 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.41 MB
Peak swap size 2.35 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_MID_4000-conf_461.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_MID_4000-conf_461_0_r966616999_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_MID_4000-conf_461_0_r966616999_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.742128
     * GNaL_b in INaL: 0.005556
     * Gto_b in Ito: 0.086351
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031984
     * GKs_b in IKs: 0.001899
     * GK1_b in IK1: 0.162958
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 71.165934
     * GKb_b in IKb: 0.003777
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035991
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11226075, states[0] = -94.201249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 22480587, states[0] = -94.097237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33682204, states[0] = -94.181372, states[40]= 0.000001
Saving checkpoint... 
Iteration: 44932602, states[0] = -94.213103, states[40]= 0.000001
Saving checkpoint... 
Iteration: 56156702, states[0] = -4.994606, states[40]= 0.000628
Saving checkpoint... 
Iteration: 67402371, states[0] = -94.214972, states[40]= 0.000001
Saving checkpoint... 
Iteration: 78509253, states[0] = -94.173403, states[40]= 0.000001
Saving checkpoint... 
Iteration: 89751613, states[0] = -94.218206, states[40]= 0.000001
Saving checkpoint... 
Iteration: 101002623, states[0] = -94.243184, states[40]= 0.000001
Saving checkpoint... 
Iteration: 112240474, states[0] = -51.168713, states[40]= 0.000499
Saving checkpoint... 
Iteration: 123452829, states[0] = -94.233700, states[40]= 0.000001
Saving checkpoint... 
Iteration: 134671081, states[0] = -94.245200, states[40]= 0.000001
Saving checkpoint... 
Iteration: 145860073, states[0] = -94.228060, states[40]= 0.000001
Saving checkpoint... 
Iteration: 157114784, states[0] = -94.247889, states[40]= 0.000001
Saving checkpoint... 
Iteration: 168355122, states[0] = -93.952927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 179474743, states[0] = -94.237693, states[40]= 0.000001
Saving checkpoint... 
Iteration: 190700114, states[0] = -94.251673, states[40]= 0.000001
Saving checkpoint... 
Iteration: 201941008, states[0] = -94.229174, states[40]= 0.000001
Saving checkpoint... 
Iteration: 213189099, states[0] = -94.246820, states[40]= 0.000001
Saving checkpoint... 
Iteration: 224416878, states[0] = -94.095947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235511187, states[0] = -94.237316, states[40]= 0.000001
Saving checkpoint... 
Iteration: 246597802, states[0] = -94.234368, states[40]= 0.000001
Saving checkpoint... 
Iteration: 257855751, states[0] = -94.230408, states[40]= 0.000001
Saving checkpoint... 
Iteration: 269107303, states[0] = -94.249464, states[40]= 0.000001
Saving checkpoint... 
Iteration: 280218407, states[0] = -37.509526, states[40]= 0.002764
Saving checkpoint... 
Iteration: 291459924, states[0] = -94.238216, states[40]= 0.000001
Saving checkpoint... 
Iteration: 302692824, states[0] = -94.250748, states[40]= 0.000001
Saving checkpoint... 
Iteration: 313918287, states[0] = -94.228963, states[40]= 0.000001
Saving checkpoint... 
Iteration: 325178544, states[0] = -94.246434, states[40]= 0.000001
Saving checkpoint... 
Iteration: 336444343, states[0] = -94.134401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 347653007, states[0] = -94.233110, states[40]= 0.000001
Saving checkpoint... 
Iteration: 358930195, states[0] = -94.254146, states[40]= 0.000001
Saving checkpoint... 
Iteration: 370197506, states[0] = -26.823167, states[40]= 0.005608
Saving checkpoint... 
Iteration: 381453038, states[0] = -94.237377, states[40]= 0.000001
Saving checkpoint... 
Iteration: 392641559, states[0] = -94.242750, states[40]= 0.000001
Saving checkpoint... 
Iteration: 403756878, states[0] = -94.230464, states[40]= 0.000001
Saving checkpoint... 
Iteration: 414999425, states[0] = -94.251487, states[40]= 0.000001
Saving checkpoint... 
Iteration: 426248186, states[0] = -59.817651, states[40]= 0.000134
Saving checkpoint... 
Iteration: 437480091, states[0] = -94.236000, states[40]= 0.000001
Saving checkpoint... 
Iteration: 448675400, states[0] = -94.247111, states[40]= 0.000001
Saving checkpoint... 
Iteration: 459900542, states[0] = -94.227484, states[40]= 0.000001
Saving checkpoint... 
Iteration: 471150912, states[0] = -94.245644, states[40]= 0.000001
Saving checkpoint... 
Iteration: 482426453, states[0] = -94.108323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493685482, states[0] = -94.230704, states[40]= 0.000001
Saving checkpoint... 
Iteration: 504883767, states[0] = -94.253355, states[40]= 0.000001
Saving checkpoint... 
Iteration: 516128450, states[0] = 4.562834, states[40]= 0.000151
Saving checkpoint... 
Iteration: 527433312, states[0] = -94.236138, states[40]= 0.000001
Saving checkpoint... 
Iteration: 538715839, states[0] = -94.249919, states[40]= 0.000001
Saving checkpoint... 
Iteration: 550016429, states[0] = 31.802770, states[40]= -0.000000
Saving checkpoint... 
Iteration: 561177987, states[0] = -94.243619, states[40]= 0.000001
Saving checkpoint... 
Iteration: 572419229, states[0] = -94.096095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583723493, states[0] = -94.228885, states[40]= 0.000001
Saving checkpoint... 
Iteration: 595001771, states[0] = -94.249230, states[40]= 0.000001
Saving checkpoint... 
Iteration: 606279481, states[0] = -93.335598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617355723, states[0] = -94.237238, states[40]= 0.000001
Saving checkpoint... 
Iteration: 628680263, states[0] = -94.245506, states[40]= 0.000001
Saving checkpoint... 
Iteration: 639996546, states[0] = -94.224007, states[40]= 0.000001
Saving checkpoint... 
Iteration: 651296359, states[0] = -94.238630, states[40]= 0.000001
Saving checkpoint... 
Iteration: 662537188, states[0] = -94.206400, states[40]= 0.000001
Saving checkpoint... 
Iteration: 673825016, states[0] = -94.226032, states[40]= 0.000001
Saving checkpoint... 
Iteration: 685097596, states[0] = -94.244897, states[40]= 0.000001
Saving checkpoint... 
Iteration: 696477133, states[0] = -94.164866, states[40]= 0.000001
Saving checkpoint... 
Iteration: 707676137, states[0] = -94.228286, states[40]= 0.000001
Saving checkpoint... 
Iteration: 718773417, states[0] = -94.250528, states[40]= 0.000001
Saving checkpoint... 
Iteration: 730010657, states[0] = 29.252370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741286014, states[0] = -94.237861, states[40]= 0.000001
Saving checkpoint... 
Iteration: 752508256, states[0] = -94.188425, states[40]= 0.000001
Saving checkpoint... 
Iteration: 763768017, states[0] = -94.225893, states[40]= 0.000001
Saving checkpoint... 
Iteration: 775037355, states[0] = -94.245875, states[40]= 0.000001
Saving checkpoint... 
Iteration: 786248274, states[0] = -59.875798, states[40]= 0.000133
Saving checkpoint... 
Iteration: 797496921, states[0] = -94.231198, states[40]= 0.000001
Saving checkpoint... 
Iteration: 808725634, states[0] = -94.247311, states[40]= 0.000001
Saving checkpoint... 
Iteration: 819903200, states[0] = -94.223066, states[40]= 0.000001
Saving checkpoint... 
Iteration: 831105906, states[0] = -94.242834, states[40]= 0.000001
Saving checkpoint... 
Iteration: 842272810, states[0] = -91.012992, states[40]= 0.000001
Saving checkpoint... 
Iteration: 853485146, states[0] = -94.230815, states[40]= 0.000001
Saving checkpoint... 
Iteration: 864667191, states[0] = -94.241005, states[40]= 0.000001
Saving checkpoint... 
Iteration: 875773010, states[0] = -94.224444, states[40]= 0.000001
Saving checkpoint... 
Iteration: 887101384, states[0] = -94.242311, states[40]= 0.000001
Saving checkpoint... 
Iteration: 898356251, states[0] = -93.950686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 909611747, states[0] = -94.227160, states[40]= 0.000001
Saving checkpoint... 
Iteration: 920867614, states[0] = -94.248534, states[40]= 0.000001
Saving checkpoint... 
Iteration: 932081059, states[0] = 22.388014, states[40]= 0.000002
Saving checkpoint... 
Iteration: 943321741, states[0] = -94.234294, states[40]= 0.000001
Saving checkpoint... 
Iteration: 954497616, states[0] = -94.178473, states[40]= 0.000001
Saving checkpoint... 
Iteration: 965767061, states[0] = -94.223451, states[40]= 0.000001
Saving checkpoint... 
Iteration: 977007888, states[0] = -94.244392, states[40]= 0.000001
Saving checkpoint... 
Iteration: 988286402, states[0] = -93.617008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 999557390, states[0] = -94.227284, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1010603365, states[0] = -94.226875, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1021852117, states[0] = -94.221373, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1032912508, states[0] = -94.246392, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1044139312, states[0] = 0.182706, states[40]= 0.000313
Saving checkpoint... 
Iteration: 1055375556, states[0] = -94.231337, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1066569371, states[0] = -94.215483, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1077785134, states[0] = -94.221780, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1089001195, states[0] = -94.243250, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1100238282, states[0] = -51.821581, states[40]= 0.000448
Saving checkpoint... 
Iteration: 1111456332, states[0] = -94.228425, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1122647201, states[0] = -94.234863, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1133877338, states[0] = -94.219627, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1145104541, states[0] = -94.239070, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1156329911, states[0] = -93.854492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167552926, states[0] = -94.225347, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1178563437, states[0] = -94.211855, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1189764017, states[0] = -94.220784, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1200968855, states[0] = -94.242884, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1212201749, states[0] = -28.571560, states[40]= 0.005471
Saving checkpoint... 
Iteration: 1223406182, states[0] = -94.228423, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1234597173, states[0] = -94.222459, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1245803439, states[0] = -94.219428, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1257043989, states[0] = -94.239798, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1268277254, states[0] = -92.987325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1279495118, states[0] = -94.225385, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1290693954, states[0] = -94.238921, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1301885531, states[0] = -94.217461, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1313107619, states[0] = -94.236921, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1324342486, states[0] = -93.899997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1335380785, states[0] = -94.227781, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1346570397, states[0] = -94.212455, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1357728538, states[0] = -94.219378, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1368881174, states[0] = -94.242906, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1380137917, states[0] = 0.773224, states[40]= 0.000287
Saving checkpoint... 
Iteration: 1391225699, states[0] = -94.231922, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1402453631, states[0] = -94.132408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1413705927, states[0] = -94.219121, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1424968438, states[0] = -94.240175, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1436228150, states[0] = -44.157629, states[40]= 0.001270
Saving checkpoint... 
Iteration: 1447513930, states[0] = -94.222874, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1458800572, states[0] = -94.242076, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1470049309, states[0] = 31.912542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481312307, states[0] = -94.228046, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1492445866, states[0] = -94.122151, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.089469
 - CaMKt in component CaMK (millimolar): 0.002624
 - cass in component intracellular_ions (millimolar): 0.000097
 - nai in component intracellular_ions (millimolar): 7.834815
 - nass in component intracellular_ions (millimolar): 7.834973
 - ki in component intracellular_ions (millimolar): 143.944732
 - kss in component intracellular_ions (millimolar): 143.944716
 - cansr in component intracellular_ions (millimolar): 1.847921
 - cajsr in component intracellular_ions (millimolar): 1.849783
 - cai in component intracellular_ions (millimolar): 0.000102
 - m in component INa (dimensionless): 0.003928
 - hf in component INa (dimensionless): 0.865173
 - hs in component INa (dimensionless): 0.865174
 - j in component INa (dimensionless): 0.865177
 - hsp in component INa (dimensionless): 0.698512
 - jp in component INa (dimensionless): 0.865178
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.707251
 - hLp in component INaL (dimensionless): 0.512673
 - a in component Ito (dimensionless): 0.000659
 - iF in component Ito (dimensionless): 0.999850
 - iS in component Ito (dimensionless): 0.990161
 - ap in component Ito (dimensionless): 0.000335
 - iFp in component Ito (dimensionless): 0.999850
 - iSp in component Ito (dimensionless): 0.995972
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.994793
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004604
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.009080
 - xs1 in component IKs (dimensionless): 0.054028
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997542
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
21:38:41 (18297): called boinc_finish(0)

</stderr_txt>
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