𝕏

Task 55744546

Name HuVeMOp_20240702153647868011_ORdGradInc_k_26-CLVPET_Block_Kr_70-conf_858_1
Workunit 26470492
Created 2 Jul 2024, 13:53:58 UTC
Sent 2 Jul 2024, 18:37:42 UTC
Report deadline 5 Jul 2024, 21:30:30 UTC
Received 4 Jul 2024, 21:31:42 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 215304
Run time 1 hours 0 min 38 sec
CPU time 1 hours 0 min 38 sec
Validate state Valid
Credit 48.95
Device peak FLOPS 4.35 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.77 MB
Peak swap size 6.23 MB
Peak disk usage 0.06 MB

Stderr output

<core_client_version>7.16.20</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-CLVPET_Block_Kr_70-conf_858.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-CLVPET_Block_Kr_70-conf_858_1_r1979660427_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-CLVPET_Block_Kr_70-conf_858_1_r1979660427_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 103.956497
     * GNaL_b in INaL: 0.006140
     * Gto_b in Ito: 0.083889
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.009407
     * GKs_b in IKs: 0.001904
     * GK1_b in IK1: 0.166398
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 69.472531
     * GKb_b in IKb: 0.003787
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032607
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 9078104, states[0] = 12.966421, states[40]= 0.004786
Saving checkpoint... 
Iteration: 18307462, states[0] = -94.721194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 28588604, states[0] = 10.290403, states[40]= 0.005177
Saving checkpoint... 
Iteration: 38807750, states[0] = -94.560425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48714664, states[0] = -35.087822, states[40]= 0.002095
Saving checkpoint... 
Iteration: 58438703, states[0] = -94.798476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67971236, states[0] = -94.808276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 77163550, states[0] = -18.176095, states[40]= 0.004080
Saving checkpoint... 
Iteration: 86392599, states[0] = -94.748431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96126937, states[0] = -2.716369, states[40]= 0.004337
Saving checkpoint... 
Iteration: 106694543, states[0] = -26.907704, states[40]= 0.004569
Saving checkpoint... 
Iteration: 116453422, states[0] = -94.783501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 126040689, states[0] = 26.267904, states[40]= 0.003152
Saving checkpoint... 
Iteration: 135445603, states[0] = -94.776610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 144853140, states[0] = -94.689799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154074972, states[0] = 16.077678, states[40]= 0.004858
Saving checkpoint... 
Iteration: 163792295, states[0] = -69.226572, states[40]= 0.000009
Saving checkpoint... 
Iteration: 173264384, states[0] = -51.685933, states[40]= 0.000177
Saving checkpoint... 
Iteration: 182528136, states[0] = 29.603355, states[40]= 0.002865
Saving checkpoint... 
Iteration: 191833816, states[0] = -94.654102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201976979, states[0] = -94.787767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212012067, states[0] = 31.048574, states[40]= 0.024536
Saving checkpoint... 
Iteration: 221707586, states[0] = -30.223113, states[40]= 0.003457
Saving checkpoint... 
Iteration: 231124745, states[0] = -1.416493, states[40]= 0.004526
Saving checkpoint... 
Iteration: 240398584, states[0] = -94.738400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 249859298, states[0] = -94.694505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259423152, states[0] = -94.757831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270116480, states[0] = 1.757028, states[40]= 0.004923
Saving checkpoint... 
Iteration: 279859770, states[0] = -94.694905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 289413526, states[0] = -94.750531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 298817748, states[0] = -94.236026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 308099591, states[0] = 7.848923, states[40]= 0.005194
Saving checkpoint... 
Iteration: 317271317, states[0] = -54.808001, states[40]= 0.000104
Saving checkpoint... 
Iteration: 326545505, states[0] = 24.974306, states[40]= 0.003434
Saving checkpoint... 
Iteration: 336625960, states[0] = -1.879944, states[40]= 0.004449
Saving checkpoint... 
Iteration: 346455983, states[0] = -94.776998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 356635557, states[0] = -5.813418, states[40]= 0.003675
Saving checkpoint... 
Iteration: 366095363, states[0] = 9.321822, states[40]= 0.005190
Saving checkpoint... 
Iteration: 375264370, states[0] = -51.439086, states[40]= 0.000184
Saving checkpoint... 
Iteration: 384392054, states[0] = -94.731566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 393586254, states[0] = 12.427573, states[40]= 0.005108
Saving checkpoint... 
Iteration: 403845736, states[0] = -94.674146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413799400, states[0] = -76.566476, states[40]= 0.000003
Saving checkpoint... 
Iteration: 423545340, states[0] = 25.022487, states[40]= 0.003425
Saving checkpoint... 
Iteration: 433202353, states[0] = -28.637590, states[40]= 0.003992
Saving checkpoint... 
Iteration: 442511233, states[0] = 30.993290, states[40]= 0.031542
Saving checkpoint... 
Iteration: 452281886, states[0] = -60.697400, states[40]= 0.000037
Saving checkpoint... 
Iteration: 462204632, states[0] = -29.304980, states[40]= 0.003767
Saving checkpoint... 
Iteration: 471817349, states[0] = -94.181135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 481179764, states[0] = -22.302499, states[40]= 0.005289
Saving checkpoint... 
Iteration: 490427589, states[0] = -94.760082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499662548, states[0] = -16.961056, states[40]= 0.003586
Saving checkpoint... 
Iteration: 509840287, states[0] = -94.664968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 519878669, states[0] = -94.717340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 529607371, states[0] = 5.093597, states[40]= 0.005136
Saving checkpoint... 
Iteration: 539135857, states[0] = -5.939056, states[40]= 0.003648
Saving checkpoint... 
Iteration: 548509593, states[0] = 30.907014, states[40]= 0.052419
Saving checkpoint... 
Iteration: 557841073, states[0] = -94.666203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567190566, states[0] = -25.306922, states[40]= 0.004952
Saving checkpoint... 
Iteration: 576451687, states[0] = -94.774214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586610644, states[0] = 3.911720, states[40]= 0.005081
Saving checkpoint... 
Iteration: 596633586, states[0] = -4.983509, states[40]= 0.003852
Saving checkpoint... 
Iteration: 606454480, states[0] = -94.775589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 616054847, states[0] = 22.266466, states[40]= 0.003955
Saving checkpoint... 
Iteration: 625395096, states[0] = -94.733877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634707765, states[0] = -30.238762, states[40]= 0.003450
Saving checkpoint... 
Iteration: 644000949, states[0] = 47.615736, states[40]= 0.096013
Saving checkpoint... 
Iteration: 653145328, states[0] = -10.013727, states[40]= 0.002871
Saving checkpoint... 
Iteration: 663280533, states[0] = -59.862196, states[40]= 0.000043
Saving checkpoint... 
Iteration: 673601362, states[0] = 7.229320, states[40]= 0.005188
Saving checkpoint... 
Iteration: 683319247, states[0] = -94.377093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 692504351, states[0] = 34.965108, states[40]= 0.262861
Saving checkpoint... 
Iteration: 701783826, states[0] = -61.947839, states[40]= 0.000030
Saving checkpoint... 
Iteration: 711930311, states[0] = -94.761356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721948554, states[0] = -94.772197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 731736537, states[0] = -39.878115, states[40]= 0.001073
Saving checkpoint... 
Iteration: 741133606, states[0] = -4.991673, states[40]= 0.003850
Saving checkpoint... 
Iteration: 750272738, states[0] = -55.524207, states[40]= 0.000092
Saving checkpoint... 
Iteration: 759494302, states[0] = -94.791973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 768742514, states[0] = -42.154265, states[40]= 0.000780
Saving checkpoint... 
Iteration: 778831336, states[0] = -94.643497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 788696525, states[0] = -26.969462, states[40]= 0.004523
Saving checkpoint... 
Iteration: 798367666, states[0] = -94.703732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 807800989, states[0] = -78.796820, states[40]= 0.000002
Saving checkpoint... 
Iteration: 817162070, states[0] = -16.790239, states[40]= 0.003512
Saving checkpoint... 
Iteration: 826310040, states[0] = -91.152195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 835462059, states[0] = -94.778771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 845553010, states[0] = 22.802844, states[40]= 0.003851
Saving checkpoint... 
Iteration: 855560935, states[0] = 20.468961, states[40]= 0.004284
Saving checkpoint... 
Iteration: 865495468, states[0] = -94.792118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 875110030, states[0] = 4.134861, states[40]= 0.005093
Saving checkpoint... 
Iteration: 884282753, states[0] = -61.245714, states[40]= 0.000034
Saving checkpoint... 
Iteration: 893661759, states[0] = -16.678431, states[40]= 0.003466
Saving checkpoint... 
Iteration: 902890909, states[0] = -94.729205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913022323, states[0] = 30.711768, states[40]= 0.003403
Saving checkpoint... 
Iteration: 923024794, states[0] = 30.304150, states[40]= 0.003033
Saving checkpoint... 
Iteration: 932854713, states[0] = -94.686204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 942341465, states[0] = -94.665949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 951736346, states[0] = -39.806711, states[40]= 0.001083
Saving checkpoint... 
Iteration: 961007269, states[0] = 31.240353, states[40]= 0.109270
Saving checkpoint... 
Iteration: 971335213, states[0] = -94.654000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981157234, states[0] = -14.977892, states[40]= 0.002919
Saving checkpoint... 
Iteration: 990446371, states[0] = -94.770363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 999713252, states[0] = -31.924040, states[40]= 0.002896
Saving checkpoint... 
Iteration: 1008971083, states[0] = -94.782440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019080124, states[0] = 14.463292, states[40]= 0.004994
Saving checkpoint... 
Iteration: 1029038785, states[0] = 26.886588, states[40]= 0.003116
Saving checkpoint... 
Iteration: 1038857191, states[0] = -94.689418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1048338108, states[0] = -94.659751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1057630966, states[0] = -3.897384, states[40]= 0.004076
Saving checkpoint... 
Iteration: 1066649407, states[0] = -11.765152, states[40]= 0.002692
Saving checkpoint... 
Iteration: 1077024231, states[0] = 30.405196, states[40]= 0.003090
Saving checkpoint... 
Iteration: 1087036770, states[0] = 27.444230, states[40]= 0.003038
Saving checkpoint... 
Iteration: 1096835204, states[0] = -94.653679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106619675, states[0] = 0.560548, states[40]= 0.004796
Saving checkpoint... 
Iteration: 1116094576, states[0] = 9.594759, states[40]= 0.005186
Saving checkpoint... 
Iteration: 1125310406, states[0] = -91.452852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1134474048, states[0] = -94.783404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1143741930, states[0] = -41.926548, states[40]= 0.000805
Saving checkpoint... 
Iteration: 1153960354, states[0] = -94.777202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1164679876, states[0] = -22.333367, states[40]= 0.005289
Saving checkpoint... 
Iteration: 1174291506, states[0] = -67.827220, states[40]= 0.000011
Saving checkpoint... 
Iteration: 1183733777, states[0] = -38.860915, states[40]= 0.001231
Saving checkpoint... 
Iteration: 1192943588, states[0] = -94.768318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1202112927, states[0] = 3.078743, states[40]= 0.005029
Saving checkpoint... 
Iteration: 1212315604, states[0] = -93.873327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1222328425, states[0] = -94.628314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1231980576, states[0] = -94.785821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1241549178, states[0] = 23.915638, states[40]= 0.003634
Saving checkpoint... 
Iteration: 1250865239, states[0] = -94.699598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1260035051, states[0] = 27.910027, states[40]= 0.002980
Saving checkpoint... 
Iteration: 1269807544, states[0] = -88.488702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1279846290, states[0] = -94.672911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1289785643, states[0] = -63.187693, states[40]= 0.000024
Saving checkpoint... 
Iteration: 1299342696, states[0] = -94.667142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1308826733, states[0] = -94.614712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1318018952, states[0] = 31.093983, states[40]= 0.004863
Saving checkpoint... 
Iteration: 1327190902, states[0] = -25.399151, states[40]= 0.004932
Saving checkpoint... 
Iteration: 1336401072, states[0] = -94.737621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346754586, states[0] = -47.080136, states[40]= 0.000372
Saving checkpoint... 
Iteration: 1357138701, states[0] = -7.150465, states[40]= 0.003391
Saving checkpoint... 
Iteration: 1366816513, states[0] = -94.050183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1376188184, states[0] = -24.647066, states[40]= 0.005081
Saving checkpoint... 
Iteration: 1385394765, states[0] = -94.731760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394619094, states[0] = 0.781330, states[40]= 0.004822
Saving checkpoint... 
Iteration: 1403964095, states[0] = -94.778376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1414062280, states[0] = 20.066631, states[40]= 0.004352
Saving checkpoint... 
Iteration: 1423962036, states[0] = -94.777365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1433805862, states[0] = -86.184824, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1443528981, states[0] = 29.433592, states[40]= 0.002875
Saving checkpoint... 
Iteration: 1452764860, states[0] = -51.662565, states[40]= 0.000177
Saving checkpoint... 
Iteration: 1461968203, states[0] = -94.780104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1472128907, states[0] = -3.057377, states[40]= 0.004239
Saving checkpoint... 
Iteration: 1482026998, states[0] = 29.870166, states[40]= 0.002907
Saving checkpoint... 
Iteration: 1491794673, states[0] = -70.892318, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1501462231, states[0] = -30.383858, states[40]= 0.001268
Saving checkpoint... 
Iteration: 1511122157, states[0] = -17.116793, states[40]= 0.003687
Saving checkpoint... 
Iteration: 1520508435, states[0] = -70.160812, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1529674295, states[0] = -94.738917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1538896021, states[0] = -94.521910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1548565351, states[0] = -56.974002, states[40]= 0.000074
Saving checkpoint... 
Iteration: 1558812408, states[0] = -94.605609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1568409549, states[0] = -94.448186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1577879232, states[0] = -94.601993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1587062188, states[0] = -94.524803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1596102383, states[0] = -94.522123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1605389940, states[0] = -94.514652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1614545944, states[0] = 26.447263, states[40]= 0.002692
Saving checkpoint... 
Iteration: 1623781151, states[0] = -94.456861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1632916914, states[0] = -49.181694, states[40]= 0.000257
Saving checkpoint... 
Iteration: 1642956431, states[0] = -63.858969, states[40]= 0.000020
Saving checkpoint... 
Iteration: 1652034774, states[0] = -94.442346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1662067777, states[0] = -94.441240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1672297137, states[0] = -94.438493, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -94.312532
 - CaMKt in component CaMK (millimolar): 0.001295
 - cass in component intracellular_ions (millimolar): 0.000082
 - nai in component intracellular_ions (millimolar): 6.173054
 - nass in component intracellular_ions (millimolar): 6.173127
 - ki in component intracellular_ions (millimolar): 145.754982
 - kss in component intracellular_ions (millimolar): 145.754975
 - cansr in component intracellular_ions (millimolar): 1.476935
 - cajsr in component intracellular_ions (millimolar): 1.476328
 - cai in component intracellular_ions (millimolar): 0.000085
 - m in component INa (dimensionless): 0.003840
 - hf in component INa (dimensionless): 0.869392
 - hs in component INa (dimensionless): 0.869392
 - j in component INa (dimensionless): 0.869393
 - hsp in component INa (dimensionless): 0.706172
 - jp in component INa (dimensionless): 0.869394
 - mL in component INaL (dimensionless): 0.000055
 - hL in component INaL (dimensionless): 0.713362
 - hLp in component INaL (dimensionless): 0.520493
 - a in component Ito (dimensionless): 0.000649
 - iF in component Ito (dimensionless): 0.999855
 - iS in component Ito (dimensionless): 0.995654
 - ap in component Ito (dimensionless): 0.000330
 - iFp in component Ito (dimensionless): 0.999855
 - iSp in component Ito (dimensionless): 0.998418
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.997376
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002434
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.003748
 - xs1 in component IKs (dimensionless): 0.037490
 - xs2 in component IKs (dimensionless): 0.000094
 - xk1 in component IK1 (dimensionless): 0.997488
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
17:31:26 (14508): called boinc_finish(0)

</stderr_txt>
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