𝕏

Task 55742837

Name HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pueyo_APDR-conf_555_0
Workunit 26469639
Created 2 Jul 2024, 13:53:06 UTC
Sent 2 Jul 2024, 18:23:12 UTC
Report deadline 6 Jul 2024, 3:59:12 UTC
Received 3 Jul 2024, 17:38:06 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236149
Run time 2 hours 4 min 24 sec
CPU time 1 hours 59 min 56 sec
Validate state Valid
Credit 60.51
Device peak FLOPS 5.55 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.19 MB
Peak swap size 3.82 MB
Peak disk usage 0.30 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pueyo_APDR-conf_555.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pueyo_APDR-conf_555_0_r573014993_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pueyo_APDR-conf_555_0_r573014993_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 106.634728
     * GNaL_b in INaL: 0.006126
     * Gto_b in Ito: 0.081402
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031381
     * GKs_b in IKs: 0.001892
     * GK1_b in IK1: 0.160429
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 69.612919
     * GKb_b in IKb: 0.003797
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037006
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8484476, states[0] = -95.104305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 22488062, states[0] = -95.064556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 36450848, states[0] = -95.037323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 49827833, states[0] = -94.982522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 63458885, states[0] = -95.018035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 76504543, states[0] = 30.453123, states[40]= 0.147921
Saving checkpoint... 
Iteration: 85454227, states[0] = -95.009502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 99502913, states[0] = 38.410930, states[40]= 0.124887
Saving checkpoint... 
Iteration: 113183860, states[0] = -94.769846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127077989, states[0] = -0.944875, states[40]= 0.004116
Saving checkpoint... 
Iteration: 141213778, states[0] = -94.834570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 155064090, states[0] = 6.100479, states[40]= 0.004794
Saving checkpoint... 
Iteration: 168379520, states[0] = -94.982637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 177525846, states[0] = 20.190743, states[40]= 0.007088
Saving checkpoint... 
Iteration: 191168668, states[0] = -93.861159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 205060004, states[0] = 7.881776, states[40]= 0.004876
Saving checkpoint... 
Iteration: 218903001, states[0] = -94.989563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 232746342, states[0] = -94.884080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 246375066, states[0] = -94.980303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259907310, states[0] = -94.990630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 273434056, states[0] = -94.997118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 287671067, states[0] = -94.315294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301243760, states[0] = -94.880446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 310384193, states[0] = -94.983459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316476298, states[0] = -95.004548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325106443, states[0] = -24.454437, states[40]= 0.000736
Saving checkpoint... 
Iteration: 334213186, states[0] = -94.831715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 347596555, states[0] = -15.230917, states[40]= 0.001431
Saving checkpoint... 
Iteration: 361510669, states[0] = 23.478451, states[40]= 0.045564
Saving checkpoint... 
Iteration: 374748630, states[0] = -94.886904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 388579691, states[0] = -1.893012, states[40]= 0.003965
Saving checkpoint... 
Iteration: 402403810, states[0] = -94.989517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 416493095, states[0] = -95.006718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425285403, states[0] = -94.926895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439263508, states[0] = -94.904886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 453319505, states[0] = -94.952760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467191247, states[0] = -94.787963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 481268107, states[0] = -94.909899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 495208469, states[0] = -94.822874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 508798271, states[0] = -94.937665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 522685138, states[0] = -94.770577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536495019, states[0] = -95.006880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550583374, states[0] = -4.303068, states[40]= 0.003526
Saving checkpoint... 
Iteration: 564460746, states[0] = -95.001975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578469235, states[0] = -95.003329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592280432, states[0] = -94.922223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 601163683, states[0] = -91.145245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 614855809, states[0] = -94.972136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 628655366, states[0] = -78.814419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641616264, states[0] = -33.680748, states[40]= 0.000308
Saving checkpoint... 
Iteration: 655342690, states[0] = -94.965853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 669096886, states[0] = -15.536626, states[40]= 0.001391
Saving checkpoint... 
Iteration: 682564953, states[0] = 5.739643, states[40]= 0.004773
Saving checkpoint... 
Iteration: 696550980, states[0] = 11.532259, states[40]= 0.005014
Saving checkpoint... 
Iteration: 710787842, states[0] = -94.928886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724474220, states[0] = -95.003994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 737905412, states[0] = -94.989770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 751498431, states[0] = -95.007158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 765596689, states[0] = -15.354329, states[40]= 0.001415
Saving checkpoint... 
Iteration: 774661344, states[0] = -88.505291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 788381198, states[0] = -94.982126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802228390, states[0] = -94.857379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 811315157, states[0] = -94.949717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 820311652, states[0] = -94.947340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 833833415, states[0] = -94.960818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 847210517, states[0] = -94.826497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 856206905, states[0] = -94.819694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 870050998, states[0] = 11.525276, states[40]= 0.005013
Saving checkpoint... 
Iteration: 883576983, states[0] = -0.284813, states[40]= 0.004208
Saving checkpoint... 
Iteration: 897758279, states[0] = -94.898588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 907478369, states[0] = -95.004484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921264237, states[0] = -94.905414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 934787442, states[0] = -94.928402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 943699966, states[0] = -94.806087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957494781, states[0] = -95.006603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 971520187, states[0] = 21.558817, states[40]= 0.009885
Saving checkpoint... 
Iteration: 985379837, states[0] = -94.981528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 999193410, states[0] = -94.792478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012890883, states[0] = -94.985248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1027102549, states[0] = -20.817819, states[40]= 0.000918
Saving checkpoint... 
Iteration: 1041030042, states[0] = 18.994683, states[40]= 0.006237
Saving checkpoint... 
Iteration: 1054496915, states[0] = -95.006801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1068061307, states[0] = 7.334246, states[40]= 0.004853
Saving checkpoint... 
Iteration: 1081916964, states[0] = -94.992633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095826524, states[0] = -94.956700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1109449701, states[0] = -94.999709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1123238017, states[0] = -94.871837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137342702, states[0] = -94.965573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1151481795, states[0] = -95.004816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165703876, states[0] = -94.813673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1179732145, states[0] = -94.863030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193220692, states[0] = -94.844439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206892691, states[0] = -94.985708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1221788337, states[0] = -94.929015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1235330942, states[0] = -94.959188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249234506, states[0] = -94.866577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1262843631, states[0] = -94.965969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276449785, states[0] = -94.999626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290695042, states[0] = -94.795793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1304680373, states[0] = -94.741283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1318537619, states[0] = 16.505372, states[40]= 0.005476
Saving checkpoint... 
Iteration: 1329969179, states[0] = -95.002876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1343060297, states[0] = 7.763457, states[40]= 0.004871
Saving checkpoint... 
Iteration: 1357140933, states[0] = -59.257307, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1370624961, states[0] = -42.148464, states[40]= 0.000094
Saving checkpoint... 
Iteration: 1383852011, states[0] = -94.969949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397919616, states[0] = -94.993105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412001451, states[0] = 49.011900, states[40]= 0.053443
Saving checkpoint... 
Iteration: 1425482496, states[0] = -95.004750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1439284840, states[0] = -94.925787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1452893511, states[0] = -94.985820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1466618174, states[0] = -35.501223, states[40]= 0.000243
Saving checkpoint... 
Iteration: 1480237813, states[0] = -94.871328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489089054, states[0] = -8.609724, states[40]= 0.002617
Saving checkpoint... 
Iteration: 1497878471, states[0] = -94.980735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1511672887, states[0] = -95.224355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1525710771, states[0] = -95.164395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1539233915, states[0] = -95.209571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1552901834, states[0] = -37.998101, states[40]= 0.000174
Saving checkpoint... 
Iteration: 1566608849, states[0] = 25.140711, states[40]= 0.067447
Saving checkpoint... 
Iteration: 1580580896, states[0] = -95.132784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1593356323, states[0] = 4.309290, states[40]= 0.005320
Saving checkpoint... 
Iteration: 1606934840, states[0] = -83.365564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1620570420, states[0] = -95.268586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1634424116, states[0] = 19.761919, states[40]= 0.008805
Saving checkpoint... 
Iteration: 1647841712, states[0] = -95.240373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1661158420, states[0] = 2.982246, states[40]= 0.005187
Saving checkpoint... 
Iteration: 1670367872, states[0] = -95.267594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1683561130, states[0] = -95.261481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1697531707, states[0] = -77.924965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1711059974, states[0] = -95.078615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1722344115, states[0] = 10.840921, states[40]= 0.005906
Saving checkpoint... 
Iteration: 1735476045, states[0] = -95.274773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1749121813, states[0] = -62.847374, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1762376385, states[0] = -95.128009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1775994837, states[0] = -95.288625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1789715417, states[0] = -95.204797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1803089522, states[0] = -12.488671, states[40]= 0.001935
Saving checkpoint... 
Iteration: 1809662913, states[0] = -93.275671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1818447032, states[0] = -95.039430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1827074823, states[0] = -0.023312, states[40]= 0.004283
Saving checkpoint... 
Iteration: 1835873581, states[0] = -95.003607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1849558030, states[0] = 8.390700, states[40]= 0.004911
Saving checkpoint... 
Iteration: 1863233584, states[0] = -94.876167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1877094826, states[0] = -14.037009, states[40]= 0.001604
Saving checkpoint... 
Iteration: 1890519880, states[0] = 21.578364, states[40]= 0.010139
Saving checkpoint... 
Iteration: 1903457664, states[0] = -95.004025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1917087731, states[0] = -7.643302, states[40]= 0.002826
Saving checkpoint... 
Iteration: 1925808958, states[0] = -94.946542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1939526154, states[0] = 20.101265, states[40]= 0.007005
Saving checkpoint... 
Iteration: 1953083340, states[0] = -4.309341, states[40]= 0.003525
Saving checkpoint... 
Iteration: 1961705378, states[0] = -94.816692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1975573662, states[0] = 1.523052, states[40]= 0.004432
Saving checkpoint... 
Iteration: 1989379915, states[0] = -94.981188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2003282771, states[0] = -94.923702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2016758347, states[0] = -94.898079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2030456773, states[0] = -95.000464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2044551371, states[0] = 11.378984, states[40]= 0.005007
Saving checkpoint... 
Iteration: 2053537610, states[0] = 16.508086, states[40]= 0.005477
Saving checkpoint... 
Iteration: 2067670925, states[0] = -94.294545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2081662070, states[0] = -89.430242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2090482770, states[0] = -95.004357, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.882378
 - CaMKt in component CaMK (millimolar): 0.006864
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.595108
 - nass in component intracellular_ions (millimolar): 6.595167
 - ki in component intracellular_ions (millimolar): 145.384769
 - kss in component intracellular_ions (millimolar): 145.384750
 - cansr in component intracellular_ions (millimolar): 1.303594
 - cajsr in component intracellular_ions (millimolar): 1.265639
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003626
 - hf in component INa (dimensionless): 0.879662
 - hs in component INa (dimensionless): 0.879658
 - j in component INa (dimensionless): 0.879629
 - hsp in component INa (dimensionless): 0.725193
 - jp in component INa (dimensionless): 0.879610
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709025
 - hLp in component INaL (dimensionless): 0.450273
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.619539
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.693909
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.933847
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999880
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001571
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.337152
 - xs1 in component IKs (dimensionless): 0.244034
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997342
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
01:20:10 (2660030): called boinc_finish(0)

</stderr_txt>
]]>


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