𝕏

Task 55741992

Name HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pueyo_APDR-conf_254_1
Workunit 26469217
Created 2 Jul 2024, 13:52:40 UTC
Sent 2 Jul 2024, 18:19:01 UTC
Report deadline 6 Jul 2024, 3:55:01 UTC
Received 3 Jul 2024, 20:40:22 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 234191
Run time 3 hours 39 min 20 sec
CPU time 2 hours 50 min 46 sec
Validate state Valid
Credit 64.50
Device peak FLOPS 2.21 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.16 MB
Peak swap size 6.22 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pueyo_APDR-conf_254.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pueyo_APDR-conf_254_1_r1284869239_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pueyo_APDR-conf_254_1_r1284869239_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 100.922506
     * GNaL_b in INaL: 0.005791
     * Gto_b in Ito: 0.084862
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032002
     * GKs_b in IKs: 0.001908
     * GK1_b in IK1: 0.161661
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 69.229788
     * GKb_b in IKb: 0.003810
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.028757
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11304577, states[0] = -95.043039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 27994801, states[0] = -95.067860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 44746096, states[0] = -94.921638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57816800, states[0] = -94.982338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 74578726, states[0] = -2.096697, states[40]= 0.003950
Saving checkpoint... 
Iteration: 86461489, states[0] = -95.025173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 103470503, states[0] = -95.023676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 114981914, states[0] = -95.024072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 131676435, states[0] = -94.714028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147879113, states[0] = -94.997391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 164326306, states[0] = -94.971319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180256051, states[0] = -94.908013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 196794182, states[0] = -94.947439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213358320, states[0] = -94.987711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 230100396, states[0] = -19.712773, states[40]= 0.000992
Saving checkpoint... 
Iteration: 246489636, states[0] = -95.021838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 263016678, states[0] = 21.841021, states[40]= 0.013856
Saving checkpoint... 
Iteration: 279832080, states[0] = -94.973960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 291416408, states[0] = -95.007792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 308055051, states[0] = 9.701122, states[40]= 0.004898
Saving checkpoint... 
Iteration: 324562412, states[0] = 6.609696, states[40]= 0.004796
Saving checkpoint... 
Iteration: 340976107, states[0] = -95.019794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357252680, states[0] = -94.903095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 369050507, states[0] = 11.501549, states[40]= 0.004949
Saving checkpoint... 
Iteration: 386211063, states[0] = -94.836239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 402675717, states[0] = -94.694438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419951380, states[0] = -95.015542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 437065806, states[0] = 5.083906, states[40]= 0.004720
Saving checkpoint... 
Iteration: 454091162, states[0] = -11.140271, states[40]= 0.002111
Saving checkpoint... 
Iteration: 470979743, states[0] = -95.020241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 487378051, states[0] = -94.995508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 503688962, states[0] = -94.789195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 520509398, states[0] = 23.287500, states[40]= 0.060382
Saving checkpoint... 
Iteration: 537555744, states[0] = 9.420552, states[40]= 0.004890
Saving checkpoint... 
Iteration: 553182297, states[0] = -94.767006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 564753760, states[0] = -94.904347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580700860, states[0] = -94.815617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 597096264, states[0] = -15.813449, states[40]= 0.001363
Saving checkpoint... 
Iteration: 613649569, states[0] = -71.687713, states[40]= 0.000001
Saving checkpoint... 
Iteration: 629507679, states[0] = 24.223973, states[40]= 0.090731
Saving checkpoint... 
Iteration: 645540576, states[0] = 15.228551, states[40]= 0.005176
Saving checkpoint... 
Iteration: 657129167, states[0] = -47.717563, states[40]= 0.000041
Saving checkpoint... 
Iteration: 673869517, states[0] = -94.992036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690320211, states[0] = -94.966300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706967749, states[0] = -95.018232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 723960935, states[0] = -95.017073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 740457431, states[0] = -95.016443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755719515, states[0] = -94.851748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 772905753, states[0] = -95.004501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789806357, states[0] = -94.956484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 806257703, states[0] = -94.909148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 823113842, states[0] = -32.422354, states[40]= 0.000364
Saving checkpoint... 
Iteration: 840077573, states[0] = -1.041208, states[40]= 0.004107
Saving checkpoint... 
Iteration: 856818978, states[0] = -94.965372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 873737955, states[0] = -94.882109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 890431253, states[0] = -95.011017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 907452002, states[0] = -95.015330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 924328761, states[0] = -94.971526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 936256362, states[0] = -94.907394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 952939384, states[0] = -95.012769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 969665244, states[0] = -93.111589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 986501630, states[0] = 46.898990, states[40]= 0.073336
Saving checkpoint... 
Iteration: 1003174939, states[0] = -94.674001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020102860, states[0] = -22.031510, states[40]= 0.000854
Saving checkpoint... 
Iteration: 1036797954, states[0] = -94.949715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1054071536, states[0] = 2.300242, states[40]= 0.004511
Saving checkpoint... 
Iteration: 1070982379, states[0] = -95.020215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1087725312, states[0] = -94.861672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103931008, states[0] = -95.010816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1120612215, states[0] = -30.872755, states[40]= 0.000434
Saving checkpoint... 
Iteration: 1137550504, states[0] = 11.502919, states[40]= 0.004949
Saving checkpoint... 
Iteration: 1154256250, states[0] = -94.907105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170907047, states[0] = -95.004606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1187045336, states[0] = 13.476648, states[40]= 0.005035
Saving checkpoint... 
Iteration: 1203520864, states[0] = 21.071445, states[40]= 0.008799
Saving checkpoint... 
Iteration: 1218322784, states[0] = -94.967610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1235081132, states[0] = -3.293766, states[40]= 0.003731
Saving checkpoint... 
Iteration: 1251373096, states[0] = -94.993082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1262904270, states[0] = -95.003736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1274662484, states[0] = -91.266232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291127441, states[0] = -45.902144, states[40]= 0.000054
Saving checkpoint... 
Iteration: 1308089840, states[0] = -9.983287, states[40]= 0.002341
Saving checkpoint... 
Iteration: 1324732943, states[0] = -94.874056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336456918, states[0] = -95.015948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1349450599, states[0] = -95.014765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1361608349, states[0] = -27.209515, states[40]= 0.000609
Saving checkpoint... 
Iteration: 1373608990, states[0] = -27.815457, states[40]= 0.000580
Saving checkpoint... 
Iteration: 1391162110, states[0] = -90.918066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1408659409, states[0] = -87.639783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425810719, states[0] = -94.959268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1442399747, states[0] = -95.002254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458913737, states[0] = -95.006273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1476440833, states[0] = -95.012722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493693866, states[0] = -94.799996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1505298765, states[0] = -95.132110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1517437569, states[0] = 14.391478, states[40]= 0.006201
Saving checkpoint... 
Iteration: 1534622130, states[0] = -62.912891, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1552296183, states[0] = -32.936685, states[40]= 0.000338
Saving checkpoint... 
Iteration: 1569609534, states[0] = 24.066125, states[40]= 0.058284
Saving checkpoint... 
Iteration: 1587004965, states[0] = 29.539090, states[40]= 0.133358
Saving checkpoint... 
Iteration: 1605139357, states[0] = -91.675781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1622328682, states[0] = -95.233132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1639188156, states[0] = -95.295468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1657027098, states[0] = -72.129167, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1674246616, states[0] = -95.257326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1691804813, states[0] = -43.370851, states[40]= 0.000083
Saving checkpoint... 
Iteration: 1707845310, states[0] = -95.255959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1724837528, states[0] = -89.862806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1741422468, states[0] = -95.225425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1758605469, states[0] = 28.308308, states[40]= 0.127453
Saving checkpoint... 
Iteration: 1770316764, states[0] = 21.772437, states[40]= 0.015218
Saving checkpoint... 
Iteration: 1780526960, states[0] = 18.392274, states[40]= 0.007550
Saving checkpoint... 
Iteration: 1797613631, states[0] = 22.618881, states[40]= 0.024980
Saving checkpoint... 
Iteration: 1809326082, states[0] = -95.019347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1821031719, states[0] = 17.761425, states[40]= 0.005719
Saving checkpoint... 
Iteration: 1837962719, states[0] = -95.040165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1849201875, states[0] = -94.834067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1859921135, states[0] = -95.020243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1876863639, states[0] = -94.996222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1893861911, states[0] = -94.992501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1910652964, states[0] = -77.270570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1923794442, states[0] = -94.948043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1940899848, states[0] = -95.003041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1959063809, states[0] = 5.976787, states[40]= 0.004768
Saving checkpoint... 
Iteration: 1976856283, states[0] = -94.985743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1995151874, states[0] = -75.205839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2012620190, states[0] = -38.564818, states[40]= 0.000162
Saving checkpoint... 
Iteration: 2030722475, states[0] = -94.856155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2048213219, states[0] = -94.839225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2066086394, states[0] = -7.130340, states[40]= 0.002948
Saving checkpoint... 
Iteration: 2083543729, states[0] = 14.076018, states[40]= 0.005073
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.897651
 - CaMKt in component CaMK (millimolar): 0.007097
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.608723
 - nass in component intracellular_ions (millimolar): 6.608784
 - ki in component intracellular_ions (millimolar): 145.366700
 - kss in component intracellular_ions (millimolar): 145.366680
 - cansr in component intracellular_ions (millimolar): 1.320103
 - cajsr in component intracellular_ions (millimolar): 1.281978
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003620
 - hf in component INa (dimensionless): 0.879928
 - hs in component INa (dimensionless): 0.879923
 - j in component INa (dimensionless): 0.879893
 - hsp in component INa (dimensionless): 0.725692
 - jp in component INa (dimensionless): 0.879873
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709694
 - hLp in component INaL (dimensionless): 0.451546
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.620910
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.695723
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935147
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999886
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001634
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.329599
 - xs1 in component IKs (dimensionless): 0.241837
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997338
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
21:40:04 (9172): called boinc_finish(0)

</stderr_txt>
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