𝕏

Task 55737023

Name HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_ENDO_3000-conf_546_0
Workunit 26466739
Created 2 Jul 2024, 13:50:04 UTC
Sent 2 Jul 2024, 17:52:44 UTC
Report deadline 5 Jul 2024, 17:52:44 UTC
Received 5 Jul 2024, 5:40:08 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 225495
Run time 2 hours 51 min 38 sec
CPU time 1 hours 44 min 59 sec
Validate state Valid
Credit 43.88
Device peak FLOPS 4.83 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.29 MB
Peak swap size 3.69 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.18.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_ENDO_3000-conf_546.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_ENDO_3000-conf_546_0_r1769293310_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_ENDO_3000-conf_546_0_r1769293310_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 101.250746
     * GNaL_b in INaL: 0.005513
     * Gto_b in Ito: 0.087665
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031324
     * GKs_b in IKs: 0.001933
     * GK1_b in IK1: 0.160114
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 70.218276
     * GKb_b in IKb: 0.003809
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031709
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 9164512, states[0] = -50.204286, states[40]= 0.000109
Saving checkpoint... 
Iteration: 18554133, states[0] = -94.045354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 28116807, states[0] = -94.018706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 37586533, states[0] = 10.275350, states[40]= 0.002077
Saving checkpoint... 
Iteration: 47272721, states[0] = -94.010464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 56945038, states[0] = -93.982704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 66321995, states[0] = -93.760321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 75525901, states[0] = -93.979597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85041052, states[0] = -93.996800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 94682794, states[0] = -58.638323, states[40]= 0.000058
Saving checkpoint... 
Iteration: 104465702, states[0] = -93.999905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 114120515, states[0] = -9.502521, states[40]= 0.002473
Saving checkpoint... 
Iteration: 123614155, states[0] = -93.998571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133124919, states[0] = -93.992673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 142289502, states[0] = -93.985846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 151409380, states[0] = -93.981476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 160901118, states[0] = -93.895979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170460319, states[0] = -93.999820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178751734, states[0] = -93.504692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 186699209, states[0] = -94.004799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194410359, states[0] = -94.001801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 202675078, states[0] = -52.418371, states[40]= 0.000155
Saving checkpoint... 
Iteration: 211136120, states[0] = -93.991886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 219253682, states[0] = -93.513889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 227419076, states[0] = -94.001339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235368327, states[0] = -93.982596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243584574, states[0] = -93.993509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 252025282, states[0] = 30.886157, states[40]= 0.000361
Saving checkpoint... 
Iteration: 260191662, states[0] = -94.004268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 267923149, states[0] = -94.001037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275964478, states[0] = -93.979219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284020272, states[0] = -93.976434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292398164, states[0] = -93.981362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301177157, states[0] = -93.989820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 309386636, states[0] = -93.877675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 317685711, states[0] = -93.989404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 326430232, states[0] = -94.000552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 334852895, states[0] = -93.824848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 343117822, states[0] = -93.992240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 351502258, states[0] = -93.969114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359681680, states[0] = -93.989433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367187563, states[0] = -93.989160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 374803661, states[0] = -93.984496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382252103, states[0] = -93.986471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 389071908, states[0] = -93.990525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396024179, states[0] = 31.039067, states[40]= 0.000494
Saving checkpoint... 
Iteration: 402956597, states[0] = -93.999188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 410687439, states[0] = -93.989020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419481047, states[0] = -93.998072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 427881791, states[0] = -93.870740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 437055897, states[0] = -93.986681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 445314830, states[0] = -93.983839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 453360830, states[0] = -93.838484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 461090691, states[0] = -93.993866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 469252066, states[0] = -93.986181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 478130514, states[0] = -93.991232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486863653, states[0] = -94.002522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 495800779, states[0] = -94.004158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 504314559, states[0] = -93.738150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 512884941, states[0] = -93.981081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521694361, states[0] = -93.988358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 530342008, states[0] = -94.003052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539226320, states[0] = -94.004266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547964040, states[0] = -93.948557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556658578, states[0] = -39.331114, states[40]= 0.000906
Saving checkpoint... 
Iteration: 565428733, states[0] = -93.979415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 573968089, states[0] = -93.998121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582956296, states[0] = -93.998599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591561738, states[0] = -93.987582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 600059639, states[0] = 20.985017, states[40]= 0.000507
Saving checkpoint... 
Iteration: 608628742, states[0] = -93.990873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 616607652, states[0] = -0.363888, states[40]= 0.003398
Saving checkpoint... 
Iteration: 624580514, states[0] = -93.991471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 632808934, states[0] = -93.983433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641249385, states[0] = -94.004122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649773411, states[0] = -93.599602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 658396737, states[0] = -93.980185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 665454208, states[0] = -93.998413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672991578, states[0] = -93.996761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 680438544, states[0] = -93.999024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 687948983, states[0] = -93.998560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 695657131, states[0] = -93.989353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 702643219, states[0] = -93.999744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 710323923, states[0] = -94.002939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 718056875, states[0] = -93.993694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725671851, states[0] = -93.988624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 732420275, states[0] = -93.914030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 738012738, states[0] = 30.980519, states[40]= 0.023076
Saving checkpoint... 
Iteration: 744841149, states[0] = -94.002360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 751960537, states[0] = -93.945655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 759580668, states[0] = -93.991050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 766981839, states[0] = -93.958011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 774939749, states[0] = -93.998658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782751453, states[0] = -93.985157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791170465, states[0] = -94.001452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 799893800, states[0] = -93.885139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 808733928, states[0] = -93.399632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 817689518, states[0] = -64.295637, states[40]= 0.000023
Saving checkpoint... 
Iteration: 825892720, states[0] = -94.000361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 834871714, states[0] = -94.001087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 843906648, states[0] = -93.999768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852614845, states[0] = -93.996169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861163791, states[0] = -43.412130, states[40]= 0.000549
Saving checkpoint... 
Iteration: 869199611, states[0] = -94.002524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 877514446, states[0] = 31.251702, states[40]= 0.012748
Saving checkpoint... 
Iteration: 885870051, states[0] = -94.000973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 894833435, states[0] = -94.002075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 903550238, states[0] = -93.983664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 911942153, states[0] = -93.977811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 920018398, states[0] = -93.973626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 928028919, states[0] = -93.994245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 935893630, states[0] = -93.979363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 943405722, states[0] = -93.978923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 951820332, states[0] = -94.002220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 959606865, states[0] = -93.990660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 967922814, states[0] = -93.915622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 976643194, states[0] = -27.609387, states[40]= 0.002231
Saving checkpoint... 
Iteration: 985003138, states[0] = -93.995205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 994695309, states[0] = -69.764142, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1004440734, states[0] = -93.997850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014014767, states[0] = 31.289755, states[40]= 0.011405
Saving checkpoint... 
Iteration: 1022987491, states[0] = -93.975990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031726910, states[0] = -93.985311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041426223, states[0] = -93.918483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1051168063, states[0] = -93.987696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059820378, states[0] = -94.001858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1069626926, states[0] = -14.801291, states[40]= 0.001733
Saving checkpoint... 
Iteration: 1079986886, states[0] = -93.975818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090157524, states[0] = -93.988016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1100169541, states[0] = -94.000365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110197653, states[0] = -72.244754, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1119879993, states[0] = -93.999844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1129596921, states[0] = 5.474576, states[40]= 0.002811
Saving checkpoint... 
Iteration: 1139495290, states[0] = -93.995037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149346190, states[0] = -93.809335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1159137055, states[0] = -93.988670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1169861257, states[0] = -93.979716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1180947323, states[0] = -93.935137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191575362, states[0] = -93.988559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201969502, states[0] = -93.949682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1212798623, states[0] = -94.001801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223470828, states[0] = -93.995831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1233803574, states[0] = -94.001640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244508550, states[0] = -93.994097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1255146853, states[0] = -93.987924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1265868722, states[0] = -93.979129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276444799, states[0] = -93.976504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1286610639, states[0] = -93.989400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296970857, states[0] = -93.995584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1307387481, states[0] = -93.998946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1317623882, states[0] = -93.995719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328024659, states[0] = -93.974486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338385059, states[0] = -93.872119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1348863053, states[0] = -93.839202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1359284210, states[0] = -93.638953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369682167, states[0] = -58.108929, states[40]= 0.000063
Saving checkpoint... 
Iteration: 1380219175, states[0] = -92.616714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1391106532, states[0] = -93.993241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401805157, states[0] = -94.001048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412589578, states[0] = -93.989911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423387213, states[0] = -93.977953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434271037, states[0] = -93.587161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444974837, states[0] = -93.951941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1455914466, states[0] = -93.997415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1466659198, states[0] = -93.986685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1477584755, states[0] = 11.064352, states[40]= 0.001820
Saving checkpoint... 
Iteration: 1488134761, states[0] = -21.170443, states[40]= 0.001786
Saving checkpoint... 
Iteration: 1498598417, states[0] = 4.727033, states[40]= 0.002926
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.849963
 - CaMKt in component CaMK (millimolar): 0.003146
 - cass in component intracellular_ions (millimolar): 0.000100
 - nai in component intracellular_ions (millimolar): 6.760161
 - nass in component intracellular_ions (millimolar): 6.760283
 - ki in component intracellular_ions (millimolar): 145.089884
 - kss in component intracellular_ions (millimolar): 145.089872
 - cansr in component intracellular_ions (millimolar): 1.840362
 - cajsr in component intracellular_ions (millimolar): 1.840184
 - cai in component intracellular_ions (millimolar): 0.000104
 - m in component INa (dimensionless): 0.004024
 - hf in component INa (dimensionless): 0.860517
 - hs in component INa (dimensionless): 0.860518
 - j in component INa (dimensionless): 0.860526
 - hsp in component INa (dimensionless): 0.690165
 - jp in component INa (dimensionless): 0.860530
 - mL in component INaL (dimensionless): 0.000061
 - hL in component INaL (dimensionless): 0.700639
 - hLp in component INaL (dimensionless): 0.502231
 - a in component Ito (dimensionless): 0.000669
 - iF in component Ito (dimensionless): 0.999843
 - iS in component Ito (dimensionless): 0.968606
 - ap in component Ito (dimensionless): 0.000341
 - iFp in component Ito (dimensionless): 0.999843
 - iSp in component Ito (dimensionless): 0.984050
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.990119
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005069
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.030271
 - xs1 in component IKs (dimensionless): 0.072966
 - xs2 in component IKs (dimensionless): 0.000099
 - xk1 in component IK1 (dimensionless): 0.997600
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
07:39:30 (626435): called boinc_finish(0)

</stderr_txt>
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