𝕏

Task 55737016

Name HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_ENDO_2000-conf_946_1
Workunit 26466735
Created 2 Jul 2024, 13:50:04 UTC
Sent 2 Jul 2024, 17:46:33 UTC
Report deadline 5 Jul 2024, 17:46:33 UTC
Received 3 Jul 2024, 1:33:56 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 228779
Run time 1 hours 46 min 35 sec
CPU time 1 hours 40 min 55 sec
Validate state Valid
Credit 43.27
Device peak FLOPS 4.70 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.75 MB
Peak swap size 4.13 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_ENDO_2000-conf_946.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_ENDO_2000-conf_946_1_r655594404_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_ENDO_2000-conf_946_1_r655594404_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.714219
     * GNaL_b in INaL: 0.006214
     * Gto_b in Ito: 0.082436
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031775
     * GKs_b in IKs: 0.001972
     * GK1_b in IK1: 0.161550
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 70.950884
     * GKb_b in IKb: 0.003834
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032937
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13150285, states[0] = -38.767362, states[40]= 0.000665
Saving checkpoint... 
Iteration: 25873180, states[0] = -94.109307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 38838032, states[0] = -94.097696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 52472413, states[0] = -94.056113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65799091, states[0] = -94.096656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 78845365, states[0] = -94.095448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 91720472, states[0] = -94.098799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 103690682, states[0] = -94.098737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117464090, states[0] = -94.053111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 129942090, states[0] = -94.091890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 142020332, states[0] = 31.801139, states[40]= 0.001694
Saving checkpoint... 
Iteration: 154543751, states[0] = -94.083219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 165864697, states[0] = -94.095683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178212051, states[0] = -92.812609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 190632939, states[0] = -94.096376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 203349592, states[0] = -93.936259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215935837, states[0] = -94.092150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229336657, states[0] = -93.912386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 242459945, states[0] = -94.050730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255141970, states[0] = -29.965856, states[40]= 0.001947
Saving checkpoint... 
Iteration: 268103912, states[0] = 0.159267, states[40]= 0.003550
Saving checkpoint... 
Iteration: 280922583, states[0] = -94.092532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292515395, states[0] = -94.074775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 304439879, states[0] = -94.037764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316854508, states[0] = -94.095535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 329885194, states[0] = -94.094106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 342855017, states[0] = -94.095390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 355083142, states[0] = 10.783473, states[40]= 0.002050
Saving checkpoint... 
Iteration: 368007831, states[0] = 30.836812, states[40]= 0.125489
Saving checkpoint... 
Iteration: 380722822, states[0] = -94.098564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 393277194, states[0] = -93.750297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 405923667, states[0] = -94.091885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 418374219, states[0] = -93.972717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 431045107, states[0] = 25.587838, states[40]= 0.000275
Saving checkpoint... 
Iteration: 443578527, states[0] = -94.088938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 456044078, states[0] = 25.934151, states[40]= 0.000259
Saving checkpoint... 
Iteration: 469144366, states[0] = -31.851689, states[40]= 0.001750
Saving checkpoint... 
Iteration: 481436123, states[0] = -94.034251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494326231, states[0] = -93.889522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507096759, states[0] = 4.227232, states[40]= 0.003192
Saving checkpoint... 
Iteration: 520184889, states[0] = -66.120464, states[40]= 0.000016
Saving checkpoint... 
Iteration: 533792898, states[0] = -94.096734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546783911, states[0] = -94.096917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 559524084, states[0] = -94.076205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 572992735, states[0] = -94.087532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 585573079, states[0] = -94.087352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 598199634, states[0] = -83.900395, states[40]= 0.000001
Saving checkpoint... 
Iteration: 611116171, states[0] = -8.663409, states[40]= 0.002700
Saving checkpoint... 
Iteration: 623259693, states[0] = -93.680079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635269546, states[0] = -93.720326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646646675, states[0] = -94.095208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 658403302, states[0] = -94.005349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 668405238, states[0] = -94.007221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 679799491, states[0] = -94.095841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 689542094, states[0] = -94.080449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 699980347, states[0] = -94.087573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 710247736, states[0] = -93.625905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721764224, states[0] = -94.096526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 731717220, states[0] = -94.096876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741296058, states[0] = -93.810853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 751034975, states[0] = 28.774386, states[40]= 0.000161
Saving checkpoint... 
Iteration: 762387614, states[0] = -93.987847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 772476616, states[0] = -94.056980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 784481935, states[0] = -94.059428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795007408, states[0] = 30.843148, states[40]= 0.145290
Saving checkpoint... 
Iteration: 804092770, states[0] = 6.274395, states[40]= 0.002877
Saving checkpoint... 
Iteration: 813400547, states[0] = -94.001808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824394910, states[0] = -93.995788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 834141089, states[0] = -29.270861, states[40]= 0.002003
Saving checkpoint... 
Iteration: 844193813, states[0] = -76.044977, states[40]= 0.000003
Saving checkpoint... 
Iteration: 854728668, states[0] = -94.096293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 865867481, states[0] = -94.092351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 876568815, states[0] = -94.085209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887034358, states[0] = 28.948667, states[40]= 0.000158
Saving checkpoint... 
Iteration: 897549662, states[0] = -94.081231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 908356770, states[0] = -93.944806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 918881595, states[0] = -94.091459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 930019137, states[0] = 31.896361, states[40]= 0.002527
Saving checkpoint... 
Iteration: 939814374, states[0] = -94.094113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 951915973, states[0] = -94.089657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 962375666, states[0] = -93.972024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 971892570, states[0] = -94.090693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981907489, states[0] = -94.089929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992486653, states[0] = -94.060544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002641870, states[0] = -94.093202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012903278, states[0] = -94.089985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1022953838, states[0] = -94.087405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033536478, states[0] = -94.077387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1043229251, states[0] = -93.527099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1053618107, states[0] = -94.091042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1063961607, states[0] = -94.086808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073571222, states[0] = -94.084697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1083173525, states[0] = -55.920180, states[40]= 0.000086
Saving checkpoint... 
Iteration: 1093656783, states[0] = -94.093635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103350230, states[0] = -93.933061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112613683, states[0] = -94.090322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1122310924, states[0] = -93.850213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1132302763, states[0] = -93.828331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1143085995, states[0] = 9.500364, states[40]= 0.002292
Saving checkpoint... 
Iteration: 1153747399, states[0] = -94.094725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1164656231, states[0] = -94.093268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1175429517, states[0] = -94.025986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186371876, states[0] = -93.965848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197302002, states[0] = -93.825884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1208131551, states[0] = -21.711412, states[40]= 0.001760
Saving checkpoint... 
Iteration: 1219893223, states[0] = -94.089477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230562383, states[0] = -94.082309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1242224724, states[0] = -93.488331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253447404, states[0] = -94.038275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1264246765, states[0] = -93.618597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1275441785, states[0] = -94.034430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287014634, states[0] = 31.896207, states[40]= 0.011837
Saving checkpoint... 
Iteration: 1299397650, states[0] = -93.996449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1309830545, states[0] = -94.091758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1321754075, states[0] = -94.093832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333412897, states[0] = -94.011275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1344248261, states[0] = -93.625262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1356162237, states[0] = -46.344452, states[40]= 0.000353
Saving checkpoint... 
Iteration: 1366439825, states[0] = -94.032640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1377303481, states[0] = -93.829139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387751257, states[0] = -94.093557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1398921218, states[0] = -94.087261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1409167224, states[0] = -50.556480, states[40]= 0.000195
Saving checkpoint... 
Iteration: 1415956784, states[0] = -94.085375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425760195, states[0] = -94.093237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1438589892, states[0] = -94.085896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450093947, states[0] = 5.685642, states[40]= 0.002974
Saving checkpoint... 
Iteration: 1461818815, states[0] = -94.091464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1472878599, states[0] = -94.088949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483840365, states[0] = -94.090543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1494777023, states[0] = -94.092560, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.958656
 - CaMKt in component CaMK (millimolar): 0.005733
 - cass in component intracellular_ions (millimolar): 0.000097
 - nai in component intracellular_ions (millimolar): 6.829529
 - nass in component intracellular_ions (millimolar): 6.829646
 - ki in component intracellular_ions (millimolar): 145.009381
 - kss in component intracellular_ions (millimolar): 145.009367
 - cansr in component intracellular_ions (millimolar): 1.843477
 - cajsr in component intracellular_ions (millimolar): 1.842570
 - cai in component intracellular_ions (millimolar): 0.000101
 - m in component INa (dimensionless): 0.003980
 - hf in component INa (dimensionless): 0.862647
 - hs in component INa (dimensionless): 0.862649
 - j in component INa (dimensionless): 0.862662
 - hsp in component INa (dimensionless): 0.693977
 - jp in component INa (dimensionless): 0.862668
 - mL in component INaL (dimensionless): 0.000059
 - hL in component INaL (dimensionless): 0.703477
 - hLp in component INaL (dimensionless): 0.490694
 - a in component Ito (dimensionless): 0.000664
 - iF in component Ito (dimensionless): 0.999846
 - iS in component Ito (dimensionless): 0.885749
 - ap in component Ito (dimensionless): 0.000338
 - iFp in component Ito (dimensionless): 0.999846
 - iSp in component Ito (dimensionless): 0.925400
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.971043
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004535
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.111537
 - xs1 in component IKs (dimensionless): 0.136537
 - xs2 in component IKs (dimensionless): 0.000098
 - xk1 in component IK1 (dimensionless): 0.997574
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
21:32:14 (23829): called boinc_finish(0)

</stderr_txt>
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