𝕏

Task 55736553

Name HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pieske_333-conf_245_0
Workunit 26466505
Created 2 Jul 2024, 13:49:49 UTC
Sent 2 Jul 2024, 17:42:22 UTC
Report deadline 5 Jul 2024, 17:42:22 UTC
Received 3 Jul 2024, 12:02:05 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 233458
Run time 1 hours 54 min 23 sec
CPU time 1 hours 53 min 21 sec
Validate state Valid
Credit 41.57
Device peak FLOPS 3.16 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.59 MB
Peak swap size 6.21 MB
Peak disk usage 0.12 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pieske_333-conf_245.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pieske_333-conf_245_0_r1816858725_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pieske_333-conf_245_0_r1816858725_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 100.730255
     * GNaL_b in INaL: 0.005556
     * Gto_b in Ito: 0.084588
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031991
     * GKs_b in IKs: 0.001955
     * GK1_b in IK1: 0.163542
     * Gncx_b in INaCa_i: 0.000970
     * Pnak_b in INaK: 71.386824
     * GKb_b in IKb: 0.003816
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029324
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 5789016, states[0] = -87.686683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 14409717, states[0] = -40.336566, states[40]= 0.000135
Saving checkpoint... 
Iteration: 23061201, states[0] = -20.184097, states[40]= 0.001216
Saving checkpoint... 
Iteration: 29070329, states[0] = -33.824963, states[40]= 0.000338
Saving checkpoint... 
Iteration: 37447512, states[0] = -87.480087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 46127306, states[0] = -87.687275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 54720754, states[0] = -14.722376, states[40]= 0.002106
Saving checkpoint... 
Iteration: 62846056, states[0] = 18.942365, states[40]= 0.012094
Saving checkpoint... 
Iteration: 71341868, states[0] = 20.317986, states[40]= 0.017147
Saving checkpoint... 
Iteration: 79981627, states[0] = -87.782323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 88557272, states[0] = -24.192371, states[40]= 0.000877
Saving checkpoint... 
Iteration: 97219376, states[0] = -18.950690, states[40]= 0.001398
Saving checkpoint... 
Iteration: 105859050, states[0] = 9.001470, states[40]= 0.007397
Saving checkpoint... 
Iteration: 114712500, states[0] = -11.711682, states[40]= 0.002819
Saving checkpoint... 
Iteration: 123355052, states[0] = 10.529779, states[40]= 0.007608
Saving checkpoint... 
Iteration: 131894458, states[0] = -35.653266, states[40]= 0.000279
Saving checkpoint... 
Iteration: 140341292, states[0] = 17.525990, states[40]= 0.010020
Saving checkpoint... 
Iteration: 149077485, states[0] = -61.407478, states[40]= 0.000007
Saving checkpoint... 
Iteration: 157713268, states[0] = -18.900883, states[40]= 0.001405
Saving checkpoint... 
Iteration: 166104298, states[0] = -87.593825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 174664385, states[0] = 20.487440, states[40]= 0.018293
Saving checkpoint... 
Iteration: 183186279, states[0] = 7.830973, states[40]= 0.007246
Saving checkpoint... 
Iteration: 191730738, states[0] = -48.060892, states[40]= 0.000051
Saving checkpoint... 
Iteration: 200426530, states[0] = -87.042136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 209000066, states[0] = 18.019343, states[40]= 0.010569
Saving checkpoint... 
Iteration: 217489445, states[0] = 22.006129, states[40]= 0.036454
Saving checkpoint... 
Iteration: 226175600, states[0] = 12.144361, states[40]= 0.007865
Saving checkpoint... 
Iteration: 234904540, states[0] = -65.057059, states[40]= 0.000004
Saving checkpoint... 
Iteration: 243553671, states[0] = -40.791152, states[40]= 0.000144
Saving checkpoint... 
Iteration: 252240738, states[0] = -72.852551, states[40]= 0.000001
Saving checkpoint... 
Iteration: 260845021, states[0] = 7.945446, states[40]= 0.007261
Saving checkpoint... 
Iteration: 269630481, states[0] = -87.787940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 278445907, states[0] = -87.729895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 285077617, states[0] = -83.280913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 293420732, states[0] = -87.434896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301623770, states[0] = -87.777092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 310000665, states[0] = 12.071110, states[40]= 0.007852
Saving checkpoint... 
Iteration: 318563766, states[0] = -66.575913, states[40]= 0.000003
Saving checkpoint... 
Iteration: 327028615, states[0] = -17.401192, states[40]= 0.001622
Saving checkpoint... 
Iteration: 335500875, states[0] = 10.274974, states[40]= 0.007572
Saving checkpoint... 
Iteration: 343869804, states[0] = -30.889236, states[40]= 0.000475
Saving checkpoint... 
Iteration: 352435397, states[0] = -87.717435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 361036732, states[0] = -33.631967, states[40]= 0.000354
Saving checkpoint... 
Iteration: 369636672, states[0] = 24.517531, states[40]= 0.087354
Saving checkpoint... 
Iteration: 378097357, states[0] = -87.708413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 386621034, states[0] = -87.794458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395316045, states[0] = 17.399893, states[40]= 0.009902
Saving checkpoint... 
Iteration: 403864677, states[0] = -32.099767, states[40]= 0.000419
Saving checkpoint... 
Iteration: 412218110, states[0] = -61.838890, states[40]= 0.000006
Saving checkpoint... 
Iteration: 420626531, states[0] = 39.101902, states[40]= 0.082270
Saving checkpoint... 
Iteration: 429137431, states[0] = 21.056644, states[40]= 0.023047
Saving checkpoint... 
Iteration: 437808532, states[0] = 18.926661, states[40]= 0.012091
Saving checkpoint... 
Iteration: 446292030, states[0] = 32.342984, states[40]= 0.123588
Saving checkpoint... 
Iteration: 453657192, states[0] = 9.275852, states[40]= 0.007434
Saving checkpoint... 
Iteration: 462084729, states[0] = -87.688794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470555838, states[0] = -78.965355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 479092575, states[0] = -87.729806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 487723345, states[0] = -82.525443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 496333438, states[0] = -2.382394, states[40]= 0.005471
Saving checkpoint... 
Iteration: 504907474, states[0] = -87.646589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 513444305, states[0] = -87.801794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 522007394, states[0] = -14.949999, states[40]= 0.002064
Saving checkpoint... 
Iteration: 527173708, states[0] = -15.179255, states[40]= 0.002018
Saving checkpoint... 
Iteration: 535884581, states[0] = -81.768965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 544595946, states[0] = -87.765319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553114158, states[0] = 34.659877, states[40]= 0.113795
Saving checkpoint... 
Iteration: 561779515, states[0] = 36.885041, states[40]= 0.100259
Saving checkpoint... 
Iteration: 570637953, states[0] = 14.089056, states[40]= 0.008281
Saving checkpoint... 
Iteration: 579286033, states[0] = 22.238718, states[40]= 0.040853
Saving checkpoint... 
Iteration: 588072764, states[0] = -87.691864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596881417, states[0] = -84.775512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 605528206, states[0] = -55.968614, states[40]= 0.000015
Saving checkpoint... 
Iteration: 614379812, states[0] = -84.883925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 622969501, states[0] = 11.985272, states[40]= 0.007837
Saving checkpoint... 
Iteration: 631688769, states[0] = -50.939119, states[40]= 0.000033
Saving checkpoint... 
Iteration: 640562981, states[0] = -87.666031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649452621, states[0] = 19.531821, states[40]= 0.013728
Saving checkpoint... 
Iteration: 658258462, states[0] = -87.788005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 666864623, states[0] = -70.565200, states[40]= 0.000002
Saving checkpoint... 
Iteration: 675571127, states[0] = -87.722584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 684221759, states[0] = -87.634528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 692601276, states[0] = 30.339047, states[40]= 0.127327
Saving checkpoint... 
Iteration: 701153498, states[0] = -11.246137, states[40]= 0.002943
Saving checkpoint... 
Iteration: 709765766, states[0] = 31.998846, states[40]= 0.124599
Saving checkpoint... 
Iteration: 718487494, states[0] = -14.595806, states[40]= 0.002137
Saving checkpoint... 
Iteration: 727013583, states[0] = -52.384395, states[40]= 0.000027
Saving checkpoint... 
Iteration: 735593467, states[0] = -41.825620, states[40]= 0.000001
Saving checkpoint... 
Iteration: 744276255, states[0] = 19.622201, states[40]= 0.014035
Saving checkpoint... 
Iteration: 752934941, states[0] = 22.410355, states[40]= 0.044300
Saving checkpoint... 
Iteration: 760512631, states[0] = -55.854714, states[40]= 0.000016
Saving checkpoint... 
Iteration: 769269521, states[0] = 21.266115, states[40]= 0.025359
Saving checkpoint... 
Iteration: 778032287, states[0] = -86.132382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 786799343, states[0] = 2.464149, states[40]= 0.006485
Saving checkpoint... 
Iteration: 795588934, states[0] = 39.558631, states[40]= 0.077610
Saving checkpoint... 
Iteration: 804090067, states[0] = 30.535628, states[40]= 0.127204
Saving checkpoint... 
Iteration: 812970380, states[0] = -4.532732, states[40]= 0.004894
Saving checkpoint... 
Iteration: 821662986, states[0] = -41.432847, states[40]= 0.000132
Saving checkpoint... 
Iteration: 830044955, states[0] = -87.671742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 838589172, states[0] = 25.174505, states[40]= 0.097667
Saving checkpoint... 
Iteration: 847192249, states[0] = -86.221200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 855748618, states[0] = 39.240392, states[40]= 0.018858
Saving checkpoint... 
Iteration: 864204141, states[0] = -87.638533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 872770207, states[0] = 16.425043, states[40]= 0.009191
Saving checkpoint... 
Iteration: 881447888, states[0] = 9.174818, states[40]= 0.007421
Saving checkpoint... 
Iteration: 890163535, states[0] = -51.813629, states[40]= 0.000029
Saving checkpoint... 
Iteration: 898745446, states[0] = 38.782004, states[40]= 0.085260
Saving checkpoint... 
Iteration: 907173333, states[0] = -69.544227, states[40]= 0.000002
Saving checkpoint... 
Iteration: 915626536, states[0] = -4.252359, states[40]= 0.004973
Saving checkpoint... 
Iteration: 920896736, states[0] = -87.781075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 929492869, states[0] = -51.719211, states[40]= 0.000030
Saving checkpoint... 
Iteration: 937927815, states[0] = 17.708682, states[40]= 0.010207
Saving checkpoint... 
Iteration: 946430926, states[0] = 15.664479, states[40]= 0.008811
Saving checkpoint... 
Iteration: 955054590, states[0] = -87.763651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 960535469, states[0] = -87.691036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966452017, states[0] = -1.270397, states[40]= 0.005741
Saving checkpoint... 
Iteration: 975004039, states[0] = -76.751474, states[40]= 0.000001
Saving checkpoint... 
Iteration: 983697197, states[0] = -87.677181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 988930936, states[0] = 13.204021, states[40]= 0.008071
Saving checkpoint... 
Iteration: 997601985, states[0] = 9.830424, states[40]= 0.007509
Saving checkpoint... 
Iteration: 1006245174, states[0] = 21.509232, states[40]= 0.028489
Saving checkpoint... 
Iteration: 1014901167, states[0] = 35.346874, states[40]= 0.109990
Saving checkpoint... 
Iteration: 1023511455, states[0] = -87.135451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031957644, states[0] = -16.728969, states[40]= 0.001732
Saving checkpoint... 
Iteration: 1040441235, states[0] = 1.941822, states[40]= 0.006395
Saving checkpoint... 
Iteration: 1049015333, states[0] = -87.577527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1057402378, states[0] = 23.565537, states[40]= 0.069139
Saving checkpoint... 
Iteration: 1066088684, states[0] = 13.922903, states[40]= 0.008239
Saving checkpoint... 
Iteration: 1074694188, states[0] = -87.706806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1083140042, states[0] = -45.894168, states[40]= 0.000070
Saving checkpoint... 
Iteration: 1086117469, states[0] = -14.704758, states[40]= 0.002115
Saving checkpoint... 
Iteration: 1094645531, states[0] = -55.342740, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1103213458, states[0] = -87.785950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1111912736, states[0] = 16.539641, states[40]= 0.009259
Saving checkpoint... 
Iteration: 1120396888, states[0] = 23.060324, states[40]= 0.058298
Saving checkpoint... 
Iteration: 1129021602, states[0] = -87.704667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137588065, states[0] = 9.774745, states[40]= 0.007502
Saving checkpoint... 
Iteration: 1146158903, states[0] = -84.006258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154727886, states[0] = 22.503082, states[40]= 0.046235
Saving checkpoint... 
Iteration: 1163484055, states[0] = -74.805709, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1172358783, states[0] = -87.737324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1181125889, states[0] = -39.850746, states[40]= 0.000164
Saving checkpoint... 
Iteration: 1189942706, states[0] = -17.962642, states[40]= 0.001536
Saving checkpoint... 
Iteration: 1198418638, states[0] = 7.421976, states[40]= 0.007194
Saving checkpoint... 
Iteration: 1206955107, states[0] = -37.737839, states[40]= 0.000216
Saving checkpoint... 
Iteration: 1214954914, states[0] = -38.574582, states[40]= 0.000194
Saving checkpoint... 
Iteration: 1223416156, states[0] = 7.408774, states[40]= 0.007192
Saving checkpoint... 
Iteration: 1231941728, states[0] = -22.556540, states[40]= 0.001009
Saving checkpoint... 
Iteration: 1240457779, states[0] = -46.079176, states[40]= 0.000068
Saving checkpoint... 
Iteration: 1249055706, states[0] = 20.953413, states[40]= 0.022030
Saving checkpoint... 
Iteration: 1257553349, states[0] = 21.518318, states[40]= 0.028621
Saving checkpoint... 
Iteration: 1266199005, states[0] = -87.791191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1274845321, states[0] = -87.724906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1283491462, states[0] = -87.566320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1292157318, states[0] = -87.567744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1300551636, states[0] = 20.544436, states[40]= 0.018683
Saving checkpoint... 
Iteration: 1309044990, states[0] = 22.895558, states[40]= 0.054680
Saving checkpoint... 
Iteration: 1317557710, states[0] = 17.117688, states[40]= 0.009661
Saving checkpoint... 
Iteration: 1326151653, states[0] = -87.483038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1334795134, states[0] = -66.025658, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1340126012, states[0] = -62.937122, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1348778658, states[0] = -43.817922, states[40]= 0.000095
Saving checkpoint... 
Iteration: 1357206318, states[0] = 23.188037, states[40]= 0.061070
Saving checkpoint... 
Iteration: 1365777794, states[0] = -44.986856, states[40]= 0.000080
Saving checkpoint... 
Iteration: 1374410545, states[0] = -0.598665, states[40]= 0.005893
Saving checkpoint... 
Iteration: 1383048566, states[0] = 18.370195, states[40]= 0.011061
Saving checkpoint... 
Iteration: 1391663465, states[0] = -87.710472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1400321517, states[0] = -87.672603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1408970910, states[0] = -86.725653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1417661238, states[0] = -87.711979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1426514456, states[0] = -87.785364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1435514821, states[0] = -87.789150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444043386, states[0] = 17.939046, states[40]= 0.010469
Saving checkpoint... 
Iteration: 1449399547, states[0] = 2.635478, states[40]= 0.006514
Saving checkpoint... 
Iteration: 1457916511, states[0] = -18.823773, states[40]= 0.001415
Saving checkpoint... 
Iteration: 1466551254, states[0] = 12.330837, states[40]= 0.007898
Saving checkpoint... 
Iteration: 1475213655, states[0] = 14.380026, states[40]= 0.008361
Saving checkpoint... 
Iteration: 1483851173, states[0] = -87.811230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1492549543, states[0] = 11.769298, states[40]= 0.007800
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -87.687973
 - CaMKt in component CaMK (millimolar): 0.042547
 - cass in component intracellular_ions (millimolar): 0.000116
 - nai in component intracellular_ions (millimolar): 6.976816
 - nass in component intracellular_ions (millimolar): 6.976965
 - ki in component intracellular_ions (millimolar): 144.943092
 - kss in component intracellular_ions (millimolar): 144.943060
 - cansr in component intracellular_ions (millimolar): 1.621178
 - cajsr in component intracellular_ions (millimolar): 1.188251
 - cai in component intracellular_ions (millimolar): 0.000112
 - m in component INa (dimensionless): 0.007485
 - hf in component INa (dimensionless): 0.691500
 - hs in component INa (dimensionless): 0.691258
 - j in component INa (dimensionless): 0.680694
 - hsp in component INa (dimensionless): 0.446211
 - jp in component INa (dimensionless): 0.654185
 - mL in component INaL (dimensionless): 0.000195
 - hL in component INaL (dimensionless): 0.292607
 - hLp in component INaL (dimensionless): 0.135912
 - a in component Ito (dimensionless): 0.001014
 - iF in component Ito (dimensionless): 0.999538
 - iS in component Ito (dimensionless): 0.175741
 - ap in component Ito (dimensionless): 0.000517
 - iFp in component Ito (dimensionless): 0.999538
 - iSp in component Ito (dimensionless): 0.212687
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.804309
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.967009
 - jca in component ICaL (dimensionless): 0.948040
 - ffp in component ICaL (dimensionless): 0.999864
 - fcafp in component ICaL (dimensionless): 0.999991
 - nca in component ICaL (dimensionless): 0.009462
 - xrf in component IKr (dimensionless): 0.028630
 - xrs in component IKr (dimensionless): 0.785315
 - xs1 in component IKs (dimensionless): 0.458754
 - xs2 in component IKs (dimensionless): 0.001186
 - xk1 in component IK1 (dimensionless): 0.996815
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
14:24:26 (10064): called boinc_finish(0)

</stderr_txt>
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