𝕏

Task 55736501

Name HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_MID_3000-conf_145_0
Workunit 26466479
Created 2 Jul 2024, 13:49:49 UTC
Sent 2 Jul 2024, 17:39:40 UTC
Report deadline 5 Jul 2024, 17:39:40 UTC
Received 4 Jul 2024, 17:21:43 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 230654
Run time 2 hours 3 min 58 sec
CPU time 1 hours 57 min 27 sec
Validate state Valid
Credit 44.29
Device peak FLOPS 3.07 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.83 MB
Peak swap size 6.39 MB
Peak disk usage 0.02 MB

Stderr output

<core_client_version>7.22.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_MID_3000-conf_145.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_MID_3000-conf_145_0_r2031898025_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_MID_3000-conf_145_0_r2031898025_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.650956
     * GNaL_b in INaL: 0.005875
     * Gto_b in Ito: 0.088368
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031297
     * GKs_b in IKs: 0.001941
     * GK1_b in IK1: 0.161752
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 71.520535
     * GKb_b in IKb: 0.003795
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029283
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 7114204, states[0] = -94.262711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17141512, states[0] = -94.227301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25629435, states[0] = 7.450092, states[40]= 0.000127
Saving checkpoint... 
Iteration: 35680964, states[0] = -94.240055, states[40]= 0.000001
Saving checkpoint... 
Iteration: 45365954, states[0] = -93.950037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 54401389, states[0] = -94.061246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 64315077, states[0] = -94.260104, states[40]= 0.000001
Saving checkpoint... 
Iteration: 73758951, states[0] = -62.292969, states[40]= 0.000122
Saving checkpoint... 
Iteration: 83284186, states[0] = -94.289083, states[40]= 0.000001
Saving checkpoint... 
Iteration: 93062290, states[0] = 28.651762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102857647, states[0] = -94.296038, states[40]= 0.000001
Saving checkpoint... 
Iteration: 112576532, states[0] = 23.884152, states[40]= 0.000002
Saving checkpoint... 
Iteration: 122323665, states[0] = -94.300804, states[40]= 0.000001
Saving checkpoint... 
Iteration: 131659354, states[0] = -94.290358, states[40]= 0.000001
Saving checkpoint... 
Iteration: 141545812, states[0] = -94.263555, states[40]= 0.000001
Saving checkpoint... 
Iteration: 151510923, states[0] = 29.378628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 160091593, states[0] = -94.295612, states[40]= 0.000001
Saving checkpoint... 
Iteration: 169477709, states[0] = -94.281382, states[40]= 0.000001
Saving checkpoint... 
Iteration: 179329719, states[0] = -94.305176, states[40]= 0.000001
Saving checkpoint... 
Iteration: 188870081, states[0] = -94.285383, states[40]= 0.000001
Saving checkpoint... 
Iteration: 198524325, states[0] = -94.254829, states[40]= 0.000001
Saving checkpoint... 
Iteration: 208207563, states[0] = -94.291680, states[40]= 0.000001
Saving checkpoint... 
Iteration: 217676053, states[0] = -20.025619, states[40]= 0.003307
Saving checkpoint... 
Iteration: 227417117, states[0] = -94.303396, states[40]= 0.000001
Saving checkpoint... 
Iteration: 237283646, states[0] = -93.604262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 246781557, states[0] = -94.305149, states[40]= 0.000001
Saving checkpoint... 
Iteration: 256293553, states[0] = -94.287885, states[40]= 0.000001
Saving checkpoint... 
Iteration: 265792644, states[0] = -93.705648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275571989, states[0] = -94.296694, states[40]= 0.000001
Saving checkpoint... 
Iteration: 285138219, states[0] = -0.222296, states[40]= 0.000501
Saving checkpoint... 
Iteration: 293617299, states[0] = -94.294460, states[40]= 0.000001
Saving checkpoint... 
Iteration: 303085375, states[0] = 20.485733, states[40]= 0.000005
Saving checkpoint... 
Iteration: 312782740, states[0] = -94.304116, states[40]= 0.000001
Saving checkpoint... 
Iteration: 322632541, states[0] = 2.200142, states[40]= 0.000351
Saving checkpoint... 
Iteration: 332415937, states[0] = -94.301831, states[40]= 0.000001
Saving checkpoint... 
Iteration: 342207014, states[0] = -32.243806, states[40]= 0.005882
Saving checkpoint... 
Iteration: 351522006, states[0] = -94.251540, states[40]= 0.000001
Saving checkpoint... 
Iteration: 361177088, states[0] = -94.290709, states[40]= 0.000001
Saving checkpoint... 
Iteration: 371099403, states[0] = -94.283154, states[40]= 0.000001
Saving checkpoint... 
Iteration: 380793108, states[0] = -94.285711, states[40]= 0.000001
Saving checkpoint... 
Iteration: 390287917, states[0] = -93.665966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399406092, states[0] = -94.121291, states[40]= 0.000001
Saving checkpoint... 
Iteration: 406366956, states[0] = -94.282526, states[40]= 0.000001
Saving checkpoint... 
Iteration: 413100146, states[0] = -94.282561, states[40]= 0.000001
Saving checkpoint... 
Iteration: 421136554, states[0] = -94.291278, states[40]= 0.000001
Saving checkpoint... 
Iteration: 428596790, states[0] = -94.292830, states[40]= 0.000001
Saving checkpoint... 
Iteration: 436225420, states[0] = -94.287308, states[40]= 0.000001
Saving checkpoint... 
Iteration: 444447098, states[0] = -94.183902, states[40]= 0.000001
Saving checkpoint... 
Iteration: 451709685, states[0] = -33.615259, states[40]= 0.005273
Saving checkpoint... 
Iteration: 459347725, states[0] = -93.967002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467941784, states[0] = -94.278826, states[40]= 0.000001
Saving checkpoint... 
Iteration: 476612246, states[0] = -94.291255, states[40]= 0.000001
Saving checkpoint... 
Iteration: 485257730, states[0] = -94.300376, states[40]= 0.000001
Saving checkpoint... 
Iteration: 493777990, states[0] = -93.276814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 501950147, states[0] = -94.297442, states[40]= 0.000001
Saving checkpoint... 
Iteration: 508024466, states[0] = -94.294386, states[40]= 0.000001
Saving checkpoint... 
Iteration: 516677489, states[0] = -94.294594, states[40]= 0.000001
Saving checkpoint... 
Iteration: 524800864, states[0] = -94.282676, states[40]= 0.000001
Saving checkpoint... 
Iteration: 533352584, states[0] = -94.299642, states[40]= 0.000001
Saving checkpoint... 
Iteration: 542387028, states[0] = -94.298698, states[40]= 0.000001
Saving checkpoint... 
Iteration: 551265854, states[0] = -94.299323, states[40]= 0.000001
Saving checkpoint... 
Iteration: 559565962, states[0] = 27.222685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 568424687, states[0] = -94.277466, states[40]= 0.000001
Saving checkpoint... 
Iteration: 576092854, states[0] = 17.694543, states[40]= 0.000012
Saving checkpoint... 
Iteration: 585000626, states[0] = 37.828466, states[40]= 0.166186
Saving checkpoint... 
Iteration: 593603828, states[0] = -94.289383, states[40]= 0.000001
Saving checkpoint... 
Iteration: 602196855, states[0] = -94.294854, states[40]= 0.000001
Saving checkpoint... 
Iteration: 610666769, states[0] = -15.553794, states[40]= 0.001324
Saving checkpoint... 
Iteration: 619335102, states[0] = -94.279605, states[40]= 0.000001
Saving checkpoint... 
Iteration: 628387901, states[0] = -94.277563, states[40]= 0.000001
Saving checkpoint... 
Iteration: 637187996, states[0] = -94.285002, states[40]= 0.000001
Saving checkpoint... 
Iteration: 646063579, states[0] = -94.290102, states[40]= 0.000001
Saving checkpoint... 
Iteration: 654829179, states[0] = -94.297651, states[40]= 0.000001
Saving checkpoint... 
Iteration: 660400458, states[0] = -94.105247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 669457387, states[0] = -94.191776, states[40]= 0.000001
Saving checkpoint... 
Iteration: 678388794, states[0] = -94.079925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686737170, states[0] = -94.282058, states[40]= 0.000001
Saving checkpoint... 
Iteration: 695092564, states[0] = -94.275052, states[40]= 0.000001
Saving checkpoint... 
Iteration: 703607752, states[0] = 11.991646, states[40]= 0.000049
Saving checkpoint... 
Iteration: 712589758, states[0] = 18.859589, states[40]= 0.000008
Saving checkpoint... 
Iteration: 721574778, states[0] = 24.288980, states[40]= 0.000002
Saving checkpoint... 
Iteration: 730540668, states[0] = 33.135186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 739529123, states[0] = 33.670591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 748517041, states[0] = 31.933501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 757580227, states[0] = 22.363049, states[40]= 0.000003
Saving checkpoint... 
Iteration: 766614151, states[0] = 9.515085, states[40]= 0.000085
Saving checkpoint... 
Iteration: 775546935, states[0] = 32.170882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 784376286, states[0] = -94.274997, states[40]= 0.000001
Saving checkpoint... 
Iteration: 793376697, states[0] = -94.274810, states[40]= 0.000001
Saving checkpoint... 
Iteration: 802333812, states[0] = -94.276167, states[40]= 0.000001
Saving checkpoint... 
Iteration: 811333352, states[0] = -94.276012, states[40]= 0.000001
Saving checkpoint... 
Iteration: 820689734, states[0] = -25.040405, states[40]= 0.007024
Saving checkpoint... 
Iteration: 828452719, states[0] = -94.183355, states[40]= 0.000001
Saving checkpoint... 
Iteration: 837521129, states[0] = -94.241741, states[40]= 0.000001
Saving checkpoint... 
Iteration: 846405284, states[0] = -94.111135, states[40]= 0.000001
Saving checkpoint... 
Iteration: 855490059, states[0] = -94.219623, states[40]= 0.000001
Saving checkpoint... 
Iteration: 864581546, states[0] = -94.268420, states[40]= 0.000001
Saving checkpoint... 
Iteration: 873290304, states[0] = -93.676986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 882723588, states[0] = -94.291391, states[40]= 0.000001
Saving checkpoint... 
Iteration: 891569366, states[0] = -94.263664, states[40]= 0.000001
Saving checkpoint... 
Iteration: 900759985, states[0] = -94.292525, states[40]= 0.000001
Saving checkpoint... 
Iteration: 909924708, states[0] = -94.290562, states[40]= 0.000001
Saving checkpoint... 
Iteration: 918941620, states[0] = -94.289806, states[40]= 0.000001
Saving checkpoint... 
Iteration: 928136823, states[0] = -94.281604, states[40]= 0.000001
Saving checkpoint... 
Iteration: 937310119, states[0] = -94.274466, states[40]= 0.000001
Saving checkpoint... 
Iteration: 946401785, states[0] = -94.271026, states[40]= 0.000001
Saving checkpoint... 
Iteration: 955126066, states[0] = -94.281547, states[40]= 0.000001
Saving checkpoint... 
Iteration: 963106443, states[0] = 12.499371, states[40]= 0.000043
Saving checkpoint... 
Iteration: 972313692, states[0] = -93.811978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981275420, states[0] = -92.762189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 990292804, states[0] = -93.692667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998412457, states[0] = -94.289271, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1006882441, states[0] = -94.058628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1015905350, states[0] = -94.107988, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1024826042, states[0] = -93.869694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033843036, states[0] = -93.938797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042671868, states[0] = -18.188100, states[40]= 0.002139
Saving checkpoint... 
Iteration: 1051738358, states[0] = -52.830273, states[40]= 0.000520
Saving checkpoint... 
Iteration: 1060655974, states[0] = -9.256997, states[40]= 0.000926
Saving checkpoint... 
Iteration: 1069237551, states[0] = -94.274753, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1078299580, states[0] = -94.272170, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1086945284, states[0] = -94.286471, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1092990173, states[0] = -94.284642, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1101864947, states[0] = -94.288570, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1111063763, states[0] = -94.281234, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1120146520, states[0] = -94.277531, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1128775661, states[0] = -94.288508, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1137509150, states[0] = -94.228379, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1146689370, states[0] = -94.283806, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1155730884, states[0] = -94.286572, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1164684596, states[0] = -94.282995, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1173318592, states[0] = -93.832219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182335558, states[0] = -93.906941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191182458, states[0] = -22.472967, states[40]= 0.005440
Saving checkpoint... 
Iteration: 1200265525, states[0] = -82.211326, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1208958316, states[0] = -94.264158, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1217513271, states[0] = -94.281330, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1225776502, states[0] = -93.013042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234678060, states[0] = -20.849470, states[40]= 0.003985
Saving checkpoint... 
Iteration: 1243613075, states[0] = 9.938018, states[40]= 0.000078
Saving checkpoint... 
Iteration: 1252554011, states[0] = 30.632639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1261661393, states[0] = -12.439496, states[40]= 0.001015
Saving checkpoint... 
Iteration: 1270641160, states[0] = -1.532608, states[40]= 0.000586
Saving checkpoint... 
Iteration: 1279508082, states[0] = 27.299946, states[40]= -0.000000
Saving checkpoint... 
Iteration: 1288514060, states[0] = 30.920560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1297123395, states[0] = -94.275148, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1306324049, states[0] = -94.266915, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1315406142, states[0] = -94.263843, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1324370134, states[0] = -94.264911, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1333681929, states[0] = -22.281138, states[40]= 0.005273
Saving checkpoint... 
Iteration: 1342395180, states[0] = -94.263700, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1350596669, states[0] = -94.263724, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1359509554, states[0] = -94.224410, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1368322470, states[0] = -93.846740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1377320879, states[0] = -93.839134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385983834, states[0] = -94.259990, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1395208953, states[0] = -33.198628, states[40]= 0.005456
Saving checkpoint... 
Iteration: 1404063486, states[0] = 27.999002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1413012814, states[0] = 30.377183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422043568, states[0] = 32.745507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1430701984, states[0] = -94.269303, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1439616008, states[0] = -94.272742, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1448935859, states[0] = -94.260308, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1458035066, states[0] = 33.620177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1466560899, states[0] = -94.274584, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1475698800, states[0] = -94.268575, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1483816236, states[0] = -93.814623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493045452, states[0] = -94.242162, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.133278
 - CaMKt in component CaMK (millimolar): 0.004575
 - cass in component intracellular_ions (millimolar): 0.000099
 - nai in component intracellular_ions (millimolar): 7.922351
 - nass in component intracellular_ions (millimolar): 7.922517
 - ki in component intracellular_ions (millimolar): 143.784532
 - kss in component intracellular_ions (millimolar): 143.784513
 - cansr in component intracellular_ions (millimolar): 1.941803
 - cajsr in component intracellular_ions (millimolar): 1.944174
 - cai in component intracellular_ions (millimolar): 0.000104
 - m in component INa (dimensionless): 0.003910
 - hf in component INa (dimensionless): 0.866011
 - hs in component INa (dimensionless): 0.866012
 - j in component INa (dimensionless): 0.866019
 - hsp in component INa (dimensionless): 0.700030
 - jp in component INa (dimensionless): 0.866023
 - mL in component INaL (dimensionless): 0.000057
 - hL in component INaL (dimensionless): 0.708511
 - hLp in component INaL (dimensionless): 0.510052
 - a in component Ito (dimensionless): 0.000657
 - iF in component Ito (dimensionless): 0.999851
 - iS in component Ito (dimensionless): 0.963792
 - ap in component Ito (dimensionless): 0.000335
 - iFp in component Ito (dimensionless): 0.999851
 - iSp in component Ito (dimensionless): 0.981061
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.985539
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004948
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.034346
 - xs1 in component IKs (dimensionless): 0.094115
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997532
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
12:21:02 (8236): called boinc_finish(0)

</stderr_txt>
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