𝕏

Task 55735383

Name HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pieske_333-conf_543_0
Workunit 26465924
Created 2 Jul 2024, 13:49:12 UTC
Sent 2 Jul 2024, 17:46:33 UTC
Report deadline 5 Jul 2024, 17:46:33 UTC
Received 3 Jul 2024, 2:40:06 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 228779
Run time 1 hours 47 min 20 sec
CPU time 1 hours 42 min 20 sec
Validate state Valid
Credit 44.04
Device peak FLOPS 4.70 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.80 MB
Peak swap size 4.13 GB
Peak disk usage 0.13 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pieske_333-conf_543.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pieske_333-conf_543_0_r1545849545_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pieske_333-conf_543_0_r1545849545_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 107.114295
     * GNaL_b in INaL: 0.005550
     * Gto_b in Ito: 0.083574
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031660
     * GKs_b in IKs: 0.001975
     * GK1_b in IK1: 0.160828
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 70.370883
     * GKb_b in IKb: 0.003792
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036775
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 13039042, states[0] = 5.869578, states[40]= 0.006817
Saving checkpoint... 
Iteration: 25865271, states[0] = 10.198491, states[40]= 0.007646
Saving checkpoint... 
Iteration: 39165524, states[0] = 35.680180, states[40]= 0.099747
Saving checkpoint... 
Iteration: 51597953, states[0] = -79.349694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 64263132, states[0] = -79.121309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 77344861, states[0] = 18.855361, states[40]= 0.012310
Saving checkpoint... 
Iteration: 89826387, states[0] = 39.568170, states[40]= 0.078559
Saving checkpoint... 
Iteration: 102897066, states[0] = -35.654429, states[40]= 0.000276
Saving checkpoint... 
Iteration: 115423603, states[0] = -77.589393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128224148, states[0] = -30.513351, states[40]= 0.000489
Saving checkpoint... 
Iteration: 142072357, states[0] = -53.245622, states[40]= 0.000023
Saving checkpoint... 
Iteration: 154745383, states[0] = -64.738730, states[40]= 0.000004
Saving checkpoint... 
Iteration: 167927094, states[0] = -86.397219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 181740835, states[0] = -61.832570, states[40]= 0.000006
Saving checkpoint... 
Iteration: 194186652, states[0] = 6.595070, states[40]= 0.007158
Saving checkpoint... 
Iteration: 207029868, states[0] = -3.551936, states[40]= 0.005167
Saving checkpoint... 
Iteration: 219938277, states[0] = -87.689622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 232184466, states[0] = 5.342002, states[40]= 0.006976
Saving checkpoint... 
Iteration: 244426314, states[0] = -87.502445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255307514, states[0] = -87.833996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266771868, states[0] = -87.717084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 278088573, states[0] = -87.440249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 288662276, states[0] = 16.229206, states[40]= 0.009382
Saving checkpoint... 
Iteration: 299248495, states[0] = -86.770082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 309403964, states[0] = -77.236271, states[40]= 0.000001
Saving checkpoint... 
Iteration: 319758452, states[0] = -87.662056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 330056524, states[0] = -57.586035, states[40]= 0.000012
Saving checkpoint... 
Iteration: 341093666, states[0] = -87.695076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 350939571, states[0] = -87.755808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 360845199, states[0] = -0.788884, states[40]= 0.005862
Saving checkpoint... 
Iteration: 371833454, states[0] = 8.150583, states[40]= 0.007379
Saving checkpoint... 
Iteration: 383050670, states[0] = -56.764938, states[40]= 0.000013
Saving checkpoint... 
Iteration: 393150054, states[0] = 17.161899, states[40]= 0.010041
Saving checkpoint... 
Iteration: 405112528, states[0] = -87.795632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415444997, states[0] = -87.796146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425243155, states[0] = -87.568594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 435318007, states[0] = 14.113467, states[40]= 0.008509
Saving checkpoint... 
Iteration: 446432793, states[0] = -87.765710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 456227475, states[0] = -83.807014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466258718, states[0] = -87.745526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 477663372, states[0] = 2.462465, states[40]= 0.006516
Saving checkpoint... 
Iteration: 488678756, states[0] = -17.278724, states[40]= 0.001637
Saving checkpoint... 
Iteration: 498685494, states[0] = -28.281836, states[40]= 0.000607
Saving checkpoint... 
Iteration: 509640085, states[0] = 16.278017, states[40]= 0.009411
Saving checkpoint... 
Iteration: 519025513, states[0] = -40.390635, states[40]= 0.000150
Saving checkpoint... 
Iteration: 530006759, states[0] = -15.568423, states[40]= 0.001938
Saving checkpoint... 
Iteration: 540429078, states[0] = -87.785102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550395036, states[0] = -87.463798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 561988202, states[0] = 2.522147, states[40]= 0.006526
Saving checkpoint... 
Iteration: 573244096, states[0] = -87.729597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583556417, states[0] = -87.298714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594374638, states[0] = -75.845180, states[40]= 0.000001
Saving checkpoint... 
Iteration: 604530599, states[0] = -59.868792, states[40]= 0.000008
Saving checkpoint... 
Iteration: 614661613, states[0] = -10.872735, states[40]= 0.003039
Saving checkpoint... 
Iteration: 624375629, states[0] = -81.933624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634923850, states[0] = -87.798447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644524602, states[0] = -56.887944, states[40]= 0.000013
Saving checkpoint... 
Iteration: 655128369, states[0] = 14.692401, states[40]= 0.008695
Saving checkpoint... 
Iteration: 665405011, states[0] = -87.743580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 675639120, states[0] = 6.122409, states[40]= 0.007090
Saving checkpoint... 
Iteration: 686203077, states[0] = -82.299613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696113849, states[0] = 19.923965, states[40]= 0.015501
Saving checkpoint... 
Iteration: 705612785, states[0] = 19.972321, states[40]= 0.015702
Saving checkpoint... 
Iteration: 715656894, states[0] = -18.479520, states[40]= 0.001458
Saving checkpoint... 
Iteration: 725432604, states[0] = 27.613419, states[40]= 0.113371
Saving checkpoint... 
Iteration: 735027949, states[0] = -77.039639, states[40]= 0.000001
Saving checkpoint... 
Iteration: 744473822, states[0] = -1.112493, states[40]= 0.005787
Saving checkpoint... 
Iteration: 754181215, states[0] = -58.236827, states[40]= 0.000011
Saving checkpoint... 
Iteration: 765074098, states[0] = -87.787428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 775888999, states[0] = -87.722745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 786843402, states[0] = -56.442682, states[40]= 0.000014
Saving checkpoint... 
Iteration: 798015076, states[0] = -65.862255, states[40]= 0.000003
Saving checkpoint... 
Iteration: 808676122, states[0] = -58.769698, states[40]= 0.000010
Saving checkpoint... 
Iteration: 820401134, states[0] = -87.784863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832033208, states[0] = -87.441628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842387653, states[0] = -87.744609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852683697, states[0] = -78.423522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 863410305, states[0] = -87.825097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 874201061, states[0] = -87.634813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 885015162, states[0] = -80.494391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 896207012, states[0] = -87.706826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 907437033, states[0] = 14.364067, states[40]= 0.008586
Saving checkpoint... 
Iteration: 919628876, states[0] = -7.892381, states[40]= 0.003900
Saving checkpoint... 
Iteration: 940851574, states[0] = -86.907678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 955329087, states[0] = -60.224614, states[40]= 0.000008
Saving checkpoint... 
Iteration: 966478455, states[0] = -37.198429, states[40]= 0.000228
Saving checkpoint... 
Iteration: 978181378, states[0] = -86.951604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989377010, states[0] = -87.759693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1001214145, states[0] = -87.777177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012841529, states[0] = -85.948965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1024419327, states[0] = 17.631364, states[40]= 0.010491
Saving checkpoint... 
Iteration: 1038796969, states[0] = -26.627122, states[40]= 0.000706
Saving checkpoint... 
Iteration: 1049718989, states[0] = -87.807800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1060723428, states[0] = -87.823615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073101856, states[0] = 4.135428, states[40]= 0.006793
Saving checkpoint... 
Iteration: 1084207882, states[0] = -87.783997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1094974520, states[0] = -49.635446, states[40]= 0.000040
Saving checkpoint... 
Iteration: 1106758659, states[0] = 9.074426, states[40]= 0.007513
Saving checkpoint... 
Iteration: 1118160962, states[0] = -83.502633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1128416175, states[0] = 13.623023, states[40]= 0.008371
Saving checkpoint... 
Iteration: 1139873581, states[0] = -87.798578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1151334115, states[0] = -87.404914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1162251387, states[0] = 10.260118, states[40]= 0.007695
Saving checkpoint... 
Iteration: 1173196076, states[0] = -87.774103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1184796083, states[0] = -45.707804, states[40]= 0.000071
Saving checkpoint... 
Iteration: 1196187983, states[0] = -87.753340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1207469504, states[0] = -58.670673, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1218710575, states[0] = -87.831352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230238663, states[0] = 14.020439, states[40]= 0.008481
Saving checkpoint... 
Iteration: 1242109620, states[0] = -26.132505, states[40]= 0.000737
Saving checkpoint... 
Iteration: 1253029382, states[0] = -87.799780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1264946389, states[0] = -34.134358, states[40]= 0.000330
Saving checkpoint... 
Iteration: 1275708869, states[0] = 34.023603, states[40]= 0.111249
Saving checkpoint... 
Iteration: 1287330480, states[0] = -87.680684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298565194, states[0] = 14.002023, states[40]= 0.008476
Saving checkpoint... 
Iteration: 1309525525, states[0] = -87.805146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1321453221, states[0] = -51.555189, states[40]= 0.000030
Saving checkpoint... 
Iteration: 1333371414, states[0] = 28.475154, states[40]= 0.117280
Saving checkpoint... 
Iteration: 1344618229, states[0] = -52.491367, states[40]= 0.000026
Saving checkpoint... 
Iteration: 1356101875, states[0] = -31.265109, states[40]= 0.000453
Saving checkpoint... 
Iteration: 1366973101, states[0] = -86.097777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1377223445, states[0] = 14.327376, states[40]= 0.008574
Saving checkpoint... 
Iteration: 1389080782, states[0] = -6.448778, states[40]= 0.004332
Saving checkpoint... 
Iteration: 1400665024, states[0] = -87.743435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411680838, states[0] = -87.801522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424166257, states[0] = -87.756957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1436534342, states[0] = 22.155983, states[40]= 0.036228
Saving checkpoint... 
Iteration: 1449793262, states[0] = -82.154133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1462399594, states[0] = 1.229903, states[40]= 0.006288
Saving checkpoint... 
Iteration: 1474867465, states[0] = 20.682696, states[40]= 0.019577
Saving checkpoint... 
Iteration: 1486999804, states[0] = -87.779632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499336029, states[0] = -87.793011, states[40]= 0.000000
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -87.708831
 - CaMKt in component CaMK (millimolar): 0.041101
 - cass in component intracellular_ions (millimolar): 0.000115
 - nai in component intracellular_ions (millimolar): 6.994299
 - nass in component intracellular_ions (millimolar): 6.994446
 - ki in component intracellular_ions (millimolar): 144.929434
 - kss in component intracellular_ions (millimolar): 144.929401
 - cansr in component intracellular_ions (millimolar): 1.605665
 - cajsr in component intracellular_ions (millimolar): 1.180348
 - cai in component intracellular_ions (millimolar): 0.000111
 - m in component INa (dimensionless): 0.007470
 - hf in component INa (dimensionless): 0.692230
 - hs in component INa (dimensionless): 0.691994
 - j in component INa (dimensionless): 0.681578
 - hsp in component INa (dimensionless): 0.447083
 - jp in component INa (dimensionless): 0.655272
 - mL in component INaL (dimensionless): 0.000194
 - hL in component INaL (dimensionless): 0.293793
 - hLp in component INaL (dimensionless): 0.136622
 - a in component Ito (dimensionless): 0.001013
 - iF in component Ito (dimensionless): 0.999540
 - iS in component Ito (dimensionless): 0.176442
 - ap in component Ito (dimensionless): 0.000516
 - iFp in component Ito (dimensionless): 0.999540
 - iSp in component Ito (dimensionless): 0.213510
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.804735
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.966861
 - jca in component ICaL (dimensionless): 0.948513
 - ffp in component ICaL (dimensionless): 0.999869
 - fcafp in component ICaL (dimensionless): 0.999992
 - nca in component ICaL (dimensionless): 0.009334
 - xrf in component IKr (dimensionless): 0.028557
 - xrs in component IKr (dimensionless): 0.790890
 - xs1 in component IKs (dimensionless): 0.457468
 - xs2 in component IKs (dimensionless): 0.001164
 - xk1 in component IK1 (dimensionless): 0.996809
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
22:04:34 (24111): called boinc_finish(0)

</stderr_txt>
]]>


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