𝕏

Task 55733349

Name HuVeMOp_20240702153647868011_ORdGradInc_k_26-TESZT_Block_K1_75-conf_40_0
Workunit 26464907
Created 2 Jul 2024, 13:48:10 UTC
Sent 2 Jul 2024, 17:22:25 UTC
Report deadline 5 Jul 2024, 17:22:25 UTC
Received 3 Jul 2024, 15:54:54 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 231073
Run time 54 min 56 sec
CPU time 48 min
Validate state Valid
Credit 44.50
Device peak FLOPS 5.32 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.77 MB
Peak swap size 32.57 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.22.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-TESZT_Block_K1_75-conf_40.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-TESZT_Block_K1_75-conf_40_0_r1309420959_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-TESZT_Block_K1_75-conf_40_0_r1309420959_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 101.644206
     * GNaL_b in INaL: 0.005898
     * Gto_b in Ito: 0.081378
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031688
     * GKs_b in IKs: 0.001896
     * GK1_b in IK1: 0.041006
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 69.903389
     * GKb_b in IKb: 0.003783
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029877
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 17279762, states[0] = -90.642147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33207160, states[0] = -82.865132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 51370138, states[0] = -90.966492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67021380, states[0] = 27.363349, states[40]= 0.001955
Saving checkpoint... 
Iteration: 83528872, states[0] = 25.469023, states[40]= 0.001319
Saving checkpoint... 
Iteration: 99607777, states[0] = -19.056683, states[40]= 0.001270
Saving checkpoint... 
Iteration: 118813039, states[0] = -90.496746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 136834990, states[0] = -90.664909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 155864646, states[0] = -90.816128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 174278252, states[0] = -89.912666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 189792711, states[0] = -90.215030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206556718, states[0] = 15.235448, states[40]= 0.002936
Saving checkpoint... 
Iteration: 223592569, states[0] = -4.458242, states[40]= 0.003701
Saving checkpoint... 
Iteration: 242231819, states[0] = -86.695956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257055117, states[0] = 15.892611, states[40]= 0.002811
Saving checkpoint... 
Iteration: 275320309, states[0] = -90.541252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 291983957, states[0] = -91.059055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 307491979, states[0] = -91.064667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 326336413, states[0] = -90.660381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 341474015, states[0] = -91.050312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354806743, states[0] = -90.405596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 371591608, states[0] = -3.680704, states[40]= 0.003836
Saving checkpoint... 
Iteration: 387943436, states[0] = -91.014099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 406872980, states[0] = -90.840822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426332932, states[0] = -90.636735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 440319063, states[0] = -90.529246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457591145, states[0] = -3.316371, states[40]= 0.003894
Saving checkpoint... 
Iteration: 475667934, states[0] = -67.628509, states[40]= 0.000004
Saving checkpoint... 
Iteration: 494162613, states[0] = -64.820870, states[40]= 0.000006
Saving checkpoint... 
Iteration: 511491330, states[0] = -91.063099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528749192, states[0] = -88.538178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 545713561, states[0] = -83.359513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 563021447, states[0] = 27.435997, states[40]= 0.001958
Saving checkpoint... 
Iteration: 580875483, states[0] = -90.849244, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595045136, states[0] = 19.812984, states[40]= 0.002081
Saving checkpoint... 
Iteration: 610692986, states[0] = -77.694354, states[40]= 0.000001
Saving checkpoint... 
Iteration: 629508544, states[0] = 28.326900, states[40]= 0.076001
Saving checkpoint... 
Iteration: 648101277, states[0] = -12.404476, states[40]= 0.002077
Saving checkpoint... 
Iteration: 665990610, states[0] = -91.061837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 684378903, states[0] = -90.860954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 702531236, states[0] = 24.792126, states[40]= 0.001385
Saving checkpoint... 
Iteration: 719902984, states[0] = -90.932940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 730933805, states[0] = -90.997233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 747311147, states[0] = -90.451762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 764934537, states[0] = -90.998286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780695507, states[0] = -78.496157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 797828543, states[0] = -90.603687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 810286834, states[0] = -90.100449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 825285340, states[0] = -90.069774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842719028, states[0] = -84.521961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 858696310, states[0] = -78.744821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 873838149, states[0] = -90.668483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 890942331, states[0] = -91.009928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 906859116, states[0] = -90.780534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 922841648, states[0] = -90.689522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940843345, states[0] = -90.699341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 956259665, states[0] = -89.202392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 971816115, states[0] = -90.499647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 988881253, states[0] = -90.867500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004277443, states[0] = -89.879798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019284906, states[0] = -90.059496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1036807573, states[0] = -90.411367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1054347096, states[0] = -90.719770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070231354, states[0] = -86.621813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1087842805, states[0] = -90.695455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102744110, states[0] = -88.104211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121957405, states[0] = -91.028921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1139490522, states[0] = -91.059406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1158298373, states[0] = -90.293684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1174949876, states[0] = -91.019149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1190681488, states[0] = -73.599071, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1208614366, states[0] = -25.258785, states[40]= 0.001106
Saving checkpoint... 
Iteration: 1226806796, states[0] = -90.401458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245144661, states[0] = -52.661721, states[40]= 0.000052
Saving checkpoint... 
Iteration: 1259173704, states[0] = -70.350821, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1276108091, states[0] = -19.173827, states[40]= 0.001265
Saving checkpoint... 
Iteration: 1294110216, states[0] = -21.258811, states[40]= 0.001180
Saving checkpoint... 
Iteration: 1311665956, states[0] = -66.616343, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1330981751, states[0] = -91.051944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1348804396, states[0] = -90.372281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368168989, states[0] = -68.145665, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1387024511, states[0] = 26.744171, states[40]= 0.001446
Saving checkpoint... 
Iteration: 1404790509, states[0] = -90.166572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422616886, states[0] = -27.650870, states[40]= 0.001034
Saving checkpoint... 
Iteration: 1441929485, states[0] = -90.986176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457424153, states[0] = -90.976226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1468113645, states[0] = -24.568838, states[40]= 0.001119
Saving checkpoint... 
Iteration: 1482749322, states[0] = -88.541422, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -90.939389
 - CaMKt in component CaMK (millimolar): 0.012460
 - cass in component intracellular_ions (millimolar): 0.000087
 - nai in component intracellular_ions (millimolar): 6.619178
 - nass in component intracellular_ions (millimolar): 6.619272
 - ki in component intracellular_ions (millimolar): 145.265580
 - kss in component intracellular_ions (millimolar): 145.265561
 - cansr in component intracellular_ions (millimolar): 1.644742
 - cajsr in component intracellular_ions (millimolar): 1.602191
 - cai in component intracellular_ions (millimolar): 0.000088
 - m in component INa (dimensionless): 0.005396
 - hf in component INa (dimensionless): 0.792713
 - hs in component INa (dimensionless): 0.792675
 - j in component INa (dimensionless): 0.792403
 - hsp in component INa (dimensionless): 0.579773
 - jp in component INa (dimensionless): 0.792184
 - mL in component INaL (dimensionless): 0.000105
 - hL in component INaL (dimensionless): 0.577772
 - hLp in component INaL (dimensionless): 0.302117
 - a in component Ito (dimensionless): 0.000814
 - iF in component Ito (dimensionless): 0.999739
 - iS in component Ito (dimensionless): 0.571697
 - ap in component Ito (dimensionless): 0.000415
 - iFp in component Ito (dimensionless): 0.999739
 - iSp in component Ito (dimensionless): 0.625605
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.914348
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999828
 - jca in component ICaL (dimensionless): 0.999972
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002959
 - xrf in component IKr (dimensionless): 0.000005
 - xrs in component IKr (dimensionless): 0.447663
 - xs1 in component IKs (dimensionless): 0.272110
 - xs2 in component IKs (dimensionless): 0.000137
 - xk1 in component IK1 (dimensionless): 0.998201
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
10:49:51 (82538): called boinc_finish(0)


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-TESZT_Block_K1_75-conf_40.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-TESZT_Block_K1_75-conf_40_0_r1309420959_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-TESZT_Block_K1_75-conf_40_0_r1309420959_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 101.644206
     * GNaL_b in INaL: 0.005898
     * Gto_b in Ito: 0.081378
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031688
     * GKs_b in IKs: 0.001896
     * GK1_b in IK1: 0.041006
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 69.903389
     * GKb_b in IKb: 0.003783
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029877
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1482749322
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -88.541422 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1494523602, states[0] = 26.965677, states[40]= 0.001537
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -90.939389
 - CaMKt in component CaMK (millimolar): 0.012460
 - cass in component intracellular_ions (millimolar): 0.000087
 - nai in component intracellular_ions (millimolar): 6.619178
 - nass in component intracellular_ions (millimolar): 6.619272
 - ki in component intracellular_ions (millimolar): 145.265580
 - kss in component intracellular_ions (millimolar): 145.265561
 - cansr in component intracellular_ions (millimolar): 1.644742
 - cajsr in component intracellular_ions (millimolar): 1.602191
 - cai in component intracellular_ions (millimolar): 0.000088
 - m in component INa (dimensionless): 0.005396
 - hf in component INa (dimensionless): 0.792713
 - hs in component INa (dimensionless): 0.792675
 - j in component INa (dimensionless): 0.792403
 - hsp in component INa (dimensionless): 0.579773
 - jp in component INa (dimensionless): 0.792184
 - mL in component INaL (dimensionless): 0.000105
 - hL in component INaL (dimensionless): 0.577772
 - hLp in component INaL (dimensionless): 0.302117
 - a in component Ito (dimensionless): 0.000814
 - iF in component Ito (dimensionless): 0.999739
 - iS in component Ito (dimensionless): 0.571697
 - ap in component Ito (dimensionless): 0.000415
 - iFp in component Ito (dimensionless): 0.999739
 - iSp in component Ito (dimensionless): 0.625605
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.914348
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999828
 - jca in component ICaL (dimensionless): 0.999972
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002959
 - xrf in component IKr (dimensionless): 0.000005
 - xrs in component IKr (dimensionless): 0.447663
 - xs1 in component IKs (dimensionless): 0.272110
 - xs2 in component IKs (dimensionless): 0.000137
 - xk1 in component IK1 (dimensionless): 0.998201
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
10:54:13 (86238): called boinc_finish(0)

</stderr_txt>
]]>


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