𝕏

Task 55731415

Name HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_MID_3000-conf_536_0
Workunit 26463941
Created 2 Jul 2024, 13:47:13 UTC
Sent 2 Jul 2024, 17:02:21 UTC
Report deadline 5 Jul 2024, 17:02:21 UTC
Received 4 Jul 2024, 0:32:49 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 227546
Run time 1 hours 23 min 44 sec
CPU time 48 min 13 sec
Validate state Valid
Credit 46.00
Device peak FLOPS 4.87 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 8.89 MB
Peak swap size 33.11 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_MID_3000-conf_536.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_MID_3000-conf_536_0_r1451863959_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_MID_3000-conf_536_0_r1451863959_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 100.873839
     * GNaL_b in INaL: 0.005934
     * Gto_b in Ito: 0.082873
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031874
     * GKs_b in IKs: 0.001945
     * GK1_b in IK1: 0.168134
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.152920
     * GKb_b in IKb: 0.003833
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032927
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 17330464, states[0] = -94.267379, states[40]= 0.000001
Saving checkpoint... 
Iteration: 34715644, states[0] = -27.730297, states[40]= 0.008015
Saving checkpoint... 
Iteration: 53097887, states[0] = -94.269381, states[40]= 0.000001
Saving checkpoint... 
Iteration: 67471204, states[0] = -94.279437, states[40]= 0.000001
Saving checkpoint... 
Iteration: 82178990, states[0] = -94.297543, states[40]= 0.000001
Saving checkpoint... 
Iteration: 95679625, states[0] = -94.302810, states[40]= 0.000001
Saving checkpoint... 
Iteration: 111536275, states[0] = -94.277304, states[40]= 0.000001
Saving checkpoint... 
Iteration: 129532510, states[0] = -94.278867, states[40]= 0.000001
Saving checkpoint... 
Iteration: 143626315, states[0] = -94.313763, states[40]= 0.000001
Saving checkpoint... 
Iteration: 158351045, states[0] = -94.324146, states[40]= 0.000001
Saving checkpoint... 
Iteration: 172032744, states[0] = -94.319003, states[40]= 0.000001
Saving checkpoint... 
Iteration: 190063783, states[0] = -94.318138, states[40]= 0.000001
Saving checkpoint... 
Iteration: 206217035, states[0] = -94.323285, states[40]= 0.000001
Saving checkpoint... 
Iteration: 219738009, states[0] = -94.324283, states[40]= 0.000001
Saving checkpoint... 
Iteration: 235444271, states[0] = -94.304362, states[40]= 0.000001
Saving checkpoint... 
Iteration: 254008164, states[0] = -94.268880, states[40]= 0.000001
Saving checkpoint... 
Iteration: 270069157, states[0] = 25.989134, states[40]= 0.000001
Saving checkpoint... 
Iteration: 287065609, states[0] = -94.295950, states[40]= 0.000001
Saving checkpoint... 
Iteration: 301584610, states[0] = 20.472062, states[40]= 0.000005
Saving checkpoint... 
Iteration: 316904304, states[0] = -94.153679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 334884808, states[0] = -94.114994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352019989, states[0] = -94.317925, states[40]= 0.000001
Saving checkpoint... 
Iteration: 368846136, states[0] = -94.305291, states[40]= 0.000001
Saving checkpoint... 
Iteration: 384945481, states[0] = -94.320037, states[40]= 0.000001
Saving checkpoint... 
Iteration: 398818400, states[0] = -94.305672, states[40]= 0.000001
Saving checkpoint... 
Iteration: 417636543, states[0] = -94.311455, states[40]= 0.000001
Saving checkpoint... 
Iteration: 438086929, states[0] = 19.604794, states[40]= 0.000006
Saving checkpoint... 
Iteration: 454924203, states[0] = -94.183061, states[40]= 0.000001
Saving checkpoint... 
Iteration: 472139352, states[0] = -94.310957, states[40]= 0.000001
Saving checkpoint... 
Iteration: 486369030, states[0] = -94.074765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 503327465, states[0] = -94.320590, states[40]= 0.000001
Saving checkpoint... 
Iteration: 522227204, states[0] = -47.044361, states[40]= 0.001084
Saving checkpoint... 
Iteration: 538054907, states[0] = -94.313073, states[40]= 0.000001
Saving checkpoint... 
Iteration: 555221557, states[0] = -42.946913, states[40]= 0.001817
Saving checkpoint... 
Iteration: 571770757, states[0] = -92.909298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592196845, states[0] = -94.306466, states[40]= 0.000001
Saving checkpoint... 
Iteration: 610041545, states[0] = -94.312246, states[40]= 0.000001
Saving checkpoint... 
Iteration: 625348494, states[0] = -94.300396, states[40]= 0.000001
Saving checkpoint... 
Iteration: 642447686, states[0] = -94.209781, states[40]= 0.000001
Saving checkpoint... 
Iteration: 659605768, states[0] = -94.308766, states[40]= 0.000001
Saving checkpoint... 
Iteration: 676813518, states[0] = -93.876088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 692571902, states[0] = -94.309503, states[40]= 0.000001
Saving checkpoint... 
Iteration: 706081583, states[0] = -94.308865, states[40]= 0.000001
Saving checkpoint... 
Iteration: 723066226, states[0] = 26.960757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 739257958, states[0] = -94.301426, states[40]= 0.000001
Saving checkpoint... 
Iteration: 757512545, states[0] = 30.846653, states[40]= -0.000000
Saving checkpoint... 
Iteration: 775791608, states[0] = -93.760148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789873263, states[0] = -94.314496, states[40]= 0.000001
Saving checkpoint... 
Iteration: 804477351, states[0] = -94.236099, states[40]= 0.000001
Saving checkpoint... 
Iteration: 819013193, states[0] = 31.140853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 833414086, states[0] = -94.312617, states[40]= 0.000001
Saving checkpoint... 
Iteration: 851176361, states[0] = -94.308665, states[40]= 0.000001
Saving checkpoint... 
Iteration: 867826027, states[0] = -94.313763, states[40]= 0.000001
Saving checkpoint... 
Iteration: 885182539, states[0] = -23.267537, states[40]= 0.005323
Saving checkpoint... 
Iteration: 901687912, states[0] = -25.227900, states[40]= 0.006309
Saving checkpoint... 
Iteration: 914460725, states[0] = -94.309575, states[40]= 0.000001
Saving checkpoint... 
Iteration: 932480177, states[0] = -94.308540, states[40]= 0.000001
Saving checkpoint... 
Iteration: 943043996, states[0] = -94.305901, states[40]= 0.000001
Saving checkpoint... 
Iteration: 946672817, states[0] = -19.471568, states[40]= 0.002485
Saving checkpoint... 
Iteration: 949256402, states[0] = -94.297533, states[40]= 0.000001
Saving checkpoint... 
Iteration: 952771141, states[0] = -92.988998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 956766837, states[0] = -94.297012, states[40]= 0.000001
Saving checkpoint... 
Iteration: 960356895, states[0] = -94.032378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964539935, states[0] = 33.354398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 968264361, states[0] = -94.311545, states[40]= 0.000001
Saving checkpoint... 
Iteration: 972551017, states[0] = -94.277553, states[40]= 0.000001
Saving checkpoint... 
Iteration: 975297756, states[0] = -93.790856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977948610, states[0] = -94.290610, states[40]= 0.000001
Saving checkpoint... 
Iteration: 981355089, states[0] = -94.026634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 984655771, states[0] = -94.303707, states[40]= 0.000001
Saving checkpoint... 
Iteration: 987799859, states[0] = -94.311588, states[40]= 0.000001
Saving checkpoint... 
Iteration: 991215672, states[0] = -94.298257, states[40]= 0.000001
Saving checkpoint... 
Iteration: 994445812, states[0] = -94.290382, states[40]= 0.000001
Saving checkpoint... 
Iteration: 998480011, states[0] = -94.307305, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1002065542, states[0] = 27.184566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005303243, states[0] = -93.819338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1008315998, states[0] = -93.881043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011283475, states[0] = -93.700914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014580624, states[0] = -94.287314, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1018047168, states[0] = -94.304367, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1022310363, states[0] = -94.310943, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1026490900, states[0] = -94.242706, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1030551968, states[0] = 31.084032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033260051, states[0] = -94.295821, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1036529445, states[0] = 33.989202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1050687872, states[0] = -94.306030, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1066225378, states[0] = -94.296483, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1082711571, states[0] = -94.296692, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1103062460, states[0] = -94.279550, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1114719671, states[0] = -41.612431, states[40]= 0.002129
Saving checkpoint... 
Iteration: 1133911320, states[0] = -94.288813, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1149981433, states[0] = -94.304414, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1167587902, states[0] = -94.286588, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1183224639, states[0] = -94.294320, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1200038249, states[0] = 33.552879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215936290, states[0] = -94.304749, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1231529441, states[0] = 33.990418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1251675262, states[0] = -94.301032, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1269166575, states[0] = -16.365620, states[40]= 0.001299
Saving checkpoint... 
Iteration: 1286170851, states[0] = -94.299904, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1301631945, states[0] = -94.295677, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1319959189, states[0] = -94.283873, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1338363920, states[0] = -94.044988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1357522683, states[0] = 33.543080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374812702, states[0] = -94.304323, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1392392568, states[0] = -94.111115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412701916, states[0] = -94.290866, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1431856684, states[0] = -94.302774, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1450643050, states[0] = -3.074934, states[40]= 0.000600
Saving checkpoint... 
Iteration: 1468174622, states[0] = -94.290872, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1481805288, states[0] = -94.285782, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.155271
 - CaMKt in component CaMK (millimolar): 0.004497
 - cass in component intracellular_ions (millimolar): 0.000099
 - nai in component intracellular_ions (millimolar): 7.976208
 - nass in component intracellular_ions (millimolar): 7.976373
 - ki in component intracellular_ions (millimolar): 143.734080
 - kss in component intracellular_ions (millimolar): 143.734061
 - cansr in component intracellular_ions (millimolar): 1.934939
 - cajsr in component intracellular_ions (millimolar): 1.937265
 - cai in component intracellular_ions (millimolar): 0.000104
 - m in component INa (dimensionless): 0.003902
 - hf in component INa (dimensionless): 0.866430
 - hs in component INa (dimensionless): 0.866431
 - j in component INa (dimensionless): 0.866438
 - hsp in component INa (dimensionless): 0.700788
 - jp in component INa (dimensionless): 0.866441
 - mL in component INaL (dimensionless): 0.000057
 - hL in component INaL (dimensionless): 0.709111
 - hLp in component INaL (dimensionless): 0.510895
 - a in component Ito (dimensionless): 0.000656
 - iF in component Ito (dimensionless): 0.999851
 - iS in component Ito (dimensionless): 0.964195
 - ap in component Ito (dimensionless): 0.000334
 - iFp in component Ito (dimensionless): 0.999851
 - iSp in component Ito (dimensionless): 0.981339
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.985718
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004911
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.033890
 - xs1 in component IKs (dimensionless): 0.093249
 - xs2 in component IKs (dimensionless): 0.000095
 - xk1 in component IK1 (dimensionless): 0.997526
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
19:35:49 (13779): called boinc_finish(0)

</stderr_txt>
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