𝕏

Task 55729636

Name HuVeMOp_20240702153647868011_ORdGradInc_k_26-Coppini_5000-conf_333_0
Workunit 26463054
Created 2 Jul 2024, 13:46:16 UTC
Sent 2 Jul 2024, 16:43:15 UTC
Report deadline 5 Jul 2024, 16:43:15 UTC
Received 3 Jul 2024, 21:48:22 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 222486
Run time 2 hours 0 min 20 sec
CPU time 1 hours 43 min 35 sec
Validate state Valid
Credit 44.09
Device peak FLOPS 3.26 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.63 MB
Peak swap size 6.22 MB
Peak disk usage 1.55 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Coppini_5000-conf_333.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Coppini_5000-conf_333_0_r146107066_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Coppini_5000-conf_333_0_r146107066_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.342785
     * GNaL_b in INaL: 0.005773
     * Gto_b in Ito: 0.087483
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031635
     * GKs_b in IKs: 0.001961
     * GK1_b in IK1: 0.160901
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 71.603759
     * GKb_b in IKb: 0.003816
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030506
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1497500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 8273490, states[0] = -94.651973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16462253, states[0] = -94.576828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24434996, states[0] = -94.527404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 32627323, states[0] = -22.393232, states[40]= 0.001370
Saving checkpoint... 
Iteration: 40937653, states[0] = -94.489861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48966495, states[0] = -94.466090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57124505, states[0] = -94.448583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65513543, states[0] = -94.430993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 74012333, states[0] = -94.440880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 82247008, states[0] = -94.429089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 90710840, states[0] = -94.443120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 99126366, states[0] = -94.428314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 107544701, states[0] = 22.327626, states[40]= 0.002210
Saving checkpoint... 
Iteration: 115948920, states[0] = -94.436549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 124184125, states[0] = -94.422103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132470302, states[0] = -94.414673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 140930648, states[0] = -94.433341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 149288259, states[0] = -94.418029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 157596894, states[0] = 2.641427, states[40]= 0.004530
Saving checkpoint... 
Iteration: 165563829, states[0] = -94.416702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 173707627, states[0] = -94.425438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 181923399, states[0] = -94.414840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 190196505, states[0] = -82.585781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 198212006, states[0] = -94.429775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 206395649, states[0] = -94.420869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 214512885, states[0] = -94.413226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 222613246, states[0] = -7.655765, states[40]= 0.003008
Saving checkpoint... 
Iteration: 230710047, states[0] = -94.429144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 238789786, states[0] = -94.422325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 246540819, states[0] = -94.418048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 252868905, states[0] = -94.314650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259784679, states[0] = -94.410814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 267127303, states[0] = -94.411824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275257351, states[0] = -94.093065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283153809, states[0] = -94.425707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290196245, states[0] = -82.057733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 298412691, states[0] = -94.429563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 306556289, states[0] = -94.417552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314754868, states[0] = -94.410800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 323127955, states[0] = -94.423360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331453298, states[0] = -94.419057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339609862, states[0] = -94.411749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 347773819, states[0] = -94.142050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 356051553, states[0] = -94.426834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 364165049, states[0] = -94.416014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 372160720, states[0] = -94.411343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 380030642, states[0] = 25.605096, states[40]= 0.001705
Saving checkpoint... 
Iteration: 388088521, states[0] = -94.418474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396389450, states[0] = -94.420043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404682441, states[0] = -94.411161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 412848038, states[0] = -94.288796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 421051743, states[0] = -94.426767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 429314186, states[0] = -94.414257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 437632498, states[0] = -22.974241, states[40]= 0.001569
Saving checkpoint... 
Iteration: 445799771, states[0] = -94.430195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 453752892, states[0] = -94.422528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462014921, states[0] = -94.412373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 469701268, states[0] = -94.410982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 477641125, states[0] = -29.680717, states[40]= 0.001380
Saving checkpoint... 
Iteration: 485901329, states[0] = -94.429508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494082590, states[0] = -94.416982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502293859, states[0] = -94.410366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 510388801, states[0] = -94.334237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 518410222, states[0] = -94.429357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 526601790, states[0] = -94.416697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534893175, states[0] = -94.409770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542897179, states[0] = -94.341595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550756388, states[0] = -94.429698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 558981313, states[0] = -94.418413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567047982, states[0] = -94.412028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 575176161, states[0] = -59.059177, states[40]= 0.000024
Saving checkpoint... 
Iteration: 583226406, states[0] = -94.428994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591389045, states[0] = -94.419901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599519769, states[0] = -94.412231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 607636721, states[0] = -26.253462, states[40]= 0.001594
Saving checkpoint... 
Iteration: 615858226, states[0] = -94.429897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624150332, states[0] = -94.415993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 632467828, states[0] = -94.409305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 640492129, states[0] = -94.395321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 648510478, states[0] = -94.427455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 656561720, states[0] = -94.417153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 664638631, states[0] = -94.411273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672970242, states[0] = -94.386640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 681066658, states[0] = -94.426257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 689284725, states[0] = -94.414376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 697688695, states[0] = -71.778959, states[40]= 0.000003
Saving checkpoint... 
Iteration: 705899148, states[0] = -94.429377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 713949352, states[0] = -94.418806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 722092269, states[0] = -94.411572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 730173001, states[0] = -56.236087, states[40]= 0.000038
Saving checkpoint... 
Iteration: 738321954, states[0] = -94.429997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746593957, states[0] = -94.416642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 754798169, states[0] = -94.410156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763094242, states[0] = -94.419010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 771426645, states[0] = -94.419134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779593312, states[0] = -94.411522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787702088, states[0] = -89.515732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795760911, states[0] = -94.429592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803934569, states[0] = -94.418980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812218676, states[0] = -94.410615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 820294218, states[0] = -94.193112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827953229, states[0] = -94.378516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 835988248, states[0] = -94.427762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 844256001, states[0] = -94.414578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852455523, states[0] = -94.409207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 860460841, states[0] = -94.382229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868725556, states[0] = -94.422772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 877081195, states[0] = -94.411543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 885576603, states[0] = -94.416246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 893976331, states[0] = -94.418247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 901841886, states[0] = -94.413627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 910061081, states[0] = 17.643909, states[40]= 0.003217
Saving checkpoint... 
Iteration: 918409897, states[0] = -94.429071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926717586, states[0] = -94.414956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 934924575, states[0] = -94.409309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 942966854, states[0] = -94.384945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 951078699, states[0] = -94.425804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 959357316, states[0] = -94.413431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 967537703, states[0] = 24.166373, states[40]= 0.001911
Saving checkpoint... 
Iteration: 975587959, states[0] = -94.417955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983824872, states[0] = -94.420762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992032117, states[0] = -94.411845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1000210421, states[0] = -93.401509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1008316936, states[0] = -94.429807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016387140, states[0] = -94.419624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1024433499, states[0] = -94.412664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1032593040, states[0] = 4.698722, states[40]= 0.004567
Saving checkpoint... 
Iteration: 1040662832, states[0] = -94.425682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1048782841, states[0] = -94.421509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056424310, states[0] = -94.418966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064745787, states[0] = -94.410256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1072970044, states[0] = -94.386263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081058752, states[0] = -94.426134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1088910740, states[0] = -94.419169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1096862360, states[0] = -94.413282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1104957266, states[0] = -94.409015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1113309653, states[0] = -94.429730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121684769, states[0] = -94.415204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1130085091, states[0] = 8.445097, states[40]= 0.004433
Saving checkpoint... 
Iteration: 1138628059, states[0] = -94.424612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147087706, states[0] = -94.411297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1155452447, states[0] = -94.377879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1163638091, states[0] = -94.424380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1171872448, states[0] = -94.413128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1180229371, states[0] = -93.992505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1188536978, states[0] = -94.426515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196745890, states[0] = -94.414435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205037848, states[0] = 24.133274, states[40]= 0.001916
Saving checkpoint... 
Iteration: 1213449654, states[0] = -94.428210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1221709266, states[0] = -94.414839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230320573, states[0] = -94.245781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1238777737, states[0] = -94.421469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1247195943, states[0] = -94.410450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1255744785, states[0] = -94.428966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1264203382, states[0] = -94.414877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1272579635, states[0] = 10.794025, states[40]= 0.004239
Saving checkpoint... 
Iteration: 1280899875, states[0] = -94.428949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1289319533, states[0] = -94.413573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1297651849, states[0] = -38.206184, states[40]= 0.000574
Saving checkpoint... 
Iteration: 1305927305, states[0] = -94.428521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1314088379, states[0] = -94.416305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1322184473, states[0] = -94.410473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1330552498, states[0] = -94.411463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1339081715, states[0] = -94.416378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1347482938, states[0] = -94.408708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355809490, states[0] = -94.429553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1364390473, states[0] = -94.412815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1372666370, states[0] = -50.439760, states[40]= 0.000099
Saving checkpoint... 
Iteration: 1380844412, states[0] = -94.429440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1389225063, states[0] = -94.414532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397496465, states[0] = -94.408604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1405754295, states[0] = -94.429041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1414073177, states[0] = -94.416441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422531216, states[0] = 25.503283, states[40]= 0.001715
Saving checkpoint... 
Iteration: 1430898247, states[0] = -94.428862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1439238932, states[0] = -94.414337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447554740, states[0] = 19.624591, states[40]= 0.002814
Saving checkpoint... 
Iteration: 1455729726, states[0] = -94.428454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1464116232, states[0] = -94.415822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1472519141, states[0] = 26.820500, states[40]= 0.003515
Saving checkpoint... 
Iteration: 1480745454, states[0] = -94.428817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1488989944, states[0] = -94.417603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497412655, states[0] = -94.408963, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.284488
 - CaMKt in component CaMK (millimolar): 0.001136
 - cass in component intracellular_ions (millimolar): 0.000087
 - nai in component intracellular_ions (millimolar): 6.297870
 - nass in component intracellular_ions (millimolar): 6.297957
 - ki in component intracellular_ions (millimolar): 145.625753
 - kss in component intracellular_ions (millimolar): 145.625742
 - cansr in component intracellular_ions (millimolar): 1.573593
 - cajsr in component intracellular_ions (millimolar): 1.573627
 - cai in component intracellular_ions (millimolar): 0.000090
 - m in component INa (dimensionless): 0.003851
 - hf in component INa (dimensionless): 0.868867
 - hs in component INa (dimensionless): 0.868868
 - j in component INa (dimensionless): 0.868869
 - hsp in component INa (dimensionless): 0.705215
 - jp in component INa (dimensionless): 0.868869
 - mL in component INaL (dimensionless): 0.000056
 - hL in component INaL (dimensionless): 0.712590
 - hLp in component INaL (dimensionless): 0.519921
 - a in component Ito (dimensionless): 0.000650
 - iF in component Ito (dimensionless): 0.999855
 - iS in component Ito (dimensionless): 0.997738
 - ap in component Ito (dimensionless): 0.000331
 - iFp in component Ito (dimensionless): 0.999855
 - iSp in component Ito (dimensionless): 0.999248
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998867
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003047
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001806
 - xs1 in component IKs (dimensionless): 0.022810
 - xs2 in component IKs (dimensionless): 0.000094
 - xk1 in component IK1 (dimensionless): 0.997495
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
21:48:06 (5212): called boinc_finish(0)

</stderr_txt>
]]>


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