𝕏

Task 55726501

Name HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_EPI_3000-conf_227_0
Workunit 26461488
Created 2 Jul 2024, 13:44:38 UTC
Sent 2 Jul 2024, 16:21:01 UTC
Report deadline 5 Jul 2024, 16:21:01 UTC
Received 3 Jul 2024, 14:03:17 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 237279
Run time 1 hours 41 min 36 sec
CPU time 1 hours 27 min 6 sec
Validate state Valid
Credit 41.84
Device peak FLOPS 3.19 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.04 MB
Peak swap size 5.25 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_EPI_3000-conf_227.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_EPI_3000-conf_227_0_r2121762750_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_EPI_3000-conf_227_0_r2121762750_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 101.415839
     * GNaL_b in INaL: 0.005494
     * Gto_b in Ito: 0.088017
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032414
     * GKs_b in IKs: 0.001929
     * GK1_b in IK1: 0.161793
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.844344
     * GKb_b in IKb: 0.003795
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032046
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 7105562, states[0] = -94.398437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17839511, states[0] = -94.317071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24993348, states[0] = -94.305773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33497459, states[0] = -94.287258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 41015313, states[0] = -94.287788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50339217, states[0] = -94.294859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59501829, states[0] = -94.289432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68553013, states[0] = -94.290252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 77462471, states[0] = -94.297832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 86450573, states[0] = -94.301365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 93165611, states[0] = -67.838142, states[40]= 0.000010
Saving checkpoint... 
Iteration: 102233258, states[0] = -93.811992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 112098989, states[0] = -94.300242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 120279536, states[0] = -94.031975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130058996, states[0] = -94.304371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 136317696, states[0] = -94.294337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143641342, states[0] = -94.301747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 150636106, states[0] = -94.321788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 158531830, states[0] = -94.307397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166644678, states[0] = -43.426225, states[40]= 0.000203
Saving checkpoint... 
Iteration: 174463457, states[0] = -94.295169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183933941, states[0] = -94.312669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192173006, states[0] = -80.220488, states[40]= 0.000002
Saving checkpoint... 
Iteration: 198886233, states[0] = -94.315085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 209105693, states[0] = -94.321581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 219733004, states[0] = -94.321599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 230553040, states[0] = -94.306717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 241542406, states[0] = 25.350311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 251810590, states[0] = -94.295844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262270849, states[0] = -94.297141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271890937, states[0] = -94.248603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280317747, states[0] = -94.295153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 281452236, states[0] = -94.310859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290670235, states[0] = -94.300658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 300392213, states[0] = -94.249310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 307041132, states[0] = -94.306116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314621878, states[0] = -94.302314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 322652738, states[0] = -53.219430, states[40]= 0.000069
Saving checkpoint... 
Iteration: 329909222, states[0] = -94.291228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 336686407, states[0] = -94.320853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 344531391, states[0] = -94.305926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 353395871, states[0] = -94.312424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 362296885, states[0] = -94.316963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 371919946, states[0] = -94.290149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 378098975, states[0] = 3.029166, states[40]= 0.000134
Saving checkpoint... 
Iteration: 387439827, states[0] = -94.281526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395869338, states[0] = -94.291365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 402784868, states[0] = -94.316756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 410286902, states[0] = -94.316539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419254776, states[0] = -94.317639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 428084960, states[0] = -94.316842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 435010629, states[0] = 20.738725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443680854, states[0] = -94.297538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450088748, states[0] = 9.150395, states[40]= 0.000046
Saving checkpoint... 
Iteration: 456645352, states[0] = -94.318777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462618235, states[0] = -94.318032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472505455, states[0] = 15.256489, states[40]= 0.000003
Saving checkpoint... 
Iteration: 480586612, states[0] = -94.316035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491853753, states[0] = -94.290192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 501597269, states[0] = -94.316361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 511783234, states[0] = -94.043063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 518420765, states[0] = -94.308264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 524546893, states[0] = -94.302007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 533874386, states[0] = -94.288749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540867698, states[0] = -94.310494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547650447, states[0] = -50.477760, states[40]= 0.000096
Saving checkpoint... 
Iteration: 555177820, states[0] = -87.876969, states[40]= 0.000001
Saving checkpoint... 
Iteration: 564424319, states[0] = -94.269342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 574473854, states[0] = -94.284903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 585232606, states[0] = -93.808527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592351263, states[0] = -94.288490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 601737520, states[0] = -93.837509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 608050865, states[0] = -94.310207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 616523180, states[0] = 24.654652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 622129327, states[0] = -94.296542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 627734852, states[0] = -94.314609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 636803228, states[0] = -94.311818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646244755, states[0] = -94.291385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 655216546, states[0] = -94.292326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 664002415, states[0] = -94.301643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673484462, states[0] = -94.282826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 680834460, states[0] = -94.287489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690294346, states[0] = -94.074438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 700002602, states[0] = -94.300997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709755469, states[0] = -93.929288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 716014290, states[0] = -94.302039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725166399, states[0] = -94.314112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 734238409, states[0] = -94.312602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 743257913, states[0] = -94.311771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 751452388, states[0] = -94.282391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 759477524, states[0] = -94.291151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 769755728, states[0] = -93.929400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779212327, states[0] = -94.312535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 788965468, states[0] = -94.281333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 797893543, states[0] = -94.283417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 807792363, states[0] = -94.309249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 817598908, states[0] = 3.078609, states[40]= 0.000132
Saving checkpoint... 
Iteration: 827497787, states[0] = -94.298958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837878503, states[0] = -94.304678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 847913121, states[0] = -94.256679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 857959422, states[0] = -94.280279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 867204031, states[0] = -93.600405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 876817855, states[0] = -94.306893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 886149379, states[0] = -94.290982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 893397314, states[0] = -94.302762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 900791838, states[0] = -94.307619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 911294307, states[0] = -94.307324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921462749, states[0] = -94.282744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931435369, states[0] = -94.279706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 941325243, states[0] = -94.305401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 950561602, states[0] = -94.293734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 960323094, states[0] = -94.140177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 970539971, states[0] = 25.568025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980514826, states[0] = -94.295414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 987627252, states[0] = -94.308989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 997093958, states[0] = -94.291437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1003995031, states[0] = -94.292200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011300774, states[0] = -94.086636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020887430, states[0] = -94.300988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1028438043, states[0] = -94.298333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1038108973, states[0] = -4.539746, states[40]= 0.000272
Saving checkpoint... 
Iteration: 1046312354, states[0] = -94.304135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1053842311, states[0] = -94.302607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1062209386, states[0] = -93.639353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070754679, states[0] = -94.283451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1079192030, states[0] = -94.307602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1088036442, states[0] = -94.299582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1097153051, states[0] = -94.307473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103707085, states[0] = -94.284722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110037059, states[0] = 25.716410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1120682159, states[0] = -91.701843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1130349408, states[0] = -94.300905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136616245, states[0] = -94.287962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1145388711, states[0] = -94.298716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1155760737, states[0] = -94.304343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1166360639, states[0] = -94.299720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1176380926, states[0] = -94.222631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186802051, states[0] = -94.086885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197062150, states[0] = 20.913553, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1207641336, states[0] = -39.532179, states[40]= 0.000284
Saving checkpoint... 
Iteration: 1217746362, states[0] = -94.281147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1228127575, states[0] = -94.285834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1235704781, states[0] = -94.282466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245728416, states[0] = -94.303823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1256038557, states[0] = -94.296931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1265981219, states[0] = -94.272366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1272840039, states[0] = -94.298817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1281251697, states[0] = -93.900804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287814818, states[0] = -94.299726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296876614, states[0] = -94.296612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306159380, states[0] = -94.283078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1315543554, states[0] = 25.225027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1324669016, states[0] = -73.738951, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1334182129, states[0] = -94.303199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1343824347, states[0] = -94.276037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350889605, states[0] = -94.295012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1360798961, states[0] = -94.075410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367251333, states[0] = -94.300919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1377946848, states[0] = -94.291676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387984939, states[0] = -94.282398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397333093, states[0] = -94.296930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1405785597, states[0] = -94.034671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415772401, states[0] = -94.276633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1427163771, states[0] = -94.301642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1433690143, states[0] = -94.279532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444070962, states[0] = -94.284528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1452398110, states[0] = -94.234043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458951083, states[0] = -94.290024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1468621759, states[0] = -17.666445, states[40]= 0.000268
Saving checkpoint... 
Iteration: 1475275654, states[0] = -94.298079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1484732253, states[0] = -94.276938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1491112922, states[0] = -8.235981, states[40]= 0.000296
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.143603
 - CaMKt in component CaMK (millimolar): 0.003688
 - cass in component intracellular_ions (millimolar): 0.000101
 - nai in component intracellular_ions (millimolar): 7.234163
 - nass in component intracellular_ions (millimolar): 7.234304
 - ki in component intracellular_ions (millimolar): 144.384992
 - kss in component intracellular_ions (millimolar): 144.384974
 - cansr in component intracellular_ions (millimolar): 2.475460
 - cajsr in component intracellular_ions (millimolar): 2.476186
 - cai in component intracellular_ions (millimolar): 0.000106
 - m in component INa (dimensionless): 0.003906
 - hf in component INa (dimensionless): 0.866208
 - hs in component INa (dimensionless): 0.866209
 - j in component INa (dimensionless): 0.866216
 - hsp in component INa (dimensionless): 0.700386
 - jp in component INa (dimensionless): 0.866220
 - mL in component INaL (dimensionless): 0.000057
 - hL in component INaL (dimensionless): 0.708794
 - hLp in component INaL (dimensionless): 0.512683
 - a in component Ito (dimensionless): 0.000656
 - iF in component Ito (dimensionless): 0.999851
 - iS in component Ito (dimensionless): 0.999851
 - ap in component Ito (dimensionless): 0.000334
 - iFp in component Ito (dimensionless): 0.999851
 - iSp in component Ito (dimensionless): 0.999851
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.991235
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005371
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.024652
 - xs1 in component IKs (dimensionless): 0.068659
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997529
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
15:12:48 (6328): called boinc_finish(0)

</stderr_txt>
]]>


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