𝕏

Task 55725187

Name HuVeMOp_20240702153647868011_ORdGradInc_k_26-CLVPET_Block_Kr_15-conf_124_0
Workunit 26460831
Created 2 Jul 2024, 13:43:47 UTC
Sent 2 Jul 2024, 16:12:16 UTC
Report deadline 5 Jul 2024, 19:05:04 UTC
Received 4 Jul 2024, 0:32:49 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 227546
Run time 1 hours 33 min 5 sec
CPU time 53 min 59 sec
Validate state Valid
Credit 55.06
Device peak FLOPS 4.87 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 9.33 MB
Peak swap size 32.86 GB
Peak disk usage 0.07 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-CLVPET_Block_Kr_15-conf_124.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-CLVPET_Block_Kr_15-conf_124_0_r1871378894_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-CLVPET_Block_Kr_15-conf_124_0_r1871378894_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 101.575104
     * GNaL_b in INaL: 0.005650
     * Gto_b in Ito: 0.082726
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.026800
     * GKs_b in IKs: 0.001911
     * GK1_b in IK1: 0.162282
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.696019
     * GKb_b in IKb: 0.003779
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031428
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 17077424, states[0] = 6.680810, states[40]= 0.004804
Saving checkpoint... 
Iteration: 32595937, states[0] = -3.852368, states[40]= 0.004103
Saving checkpoint... 
Iteration: 50300876, states[0] = -94.745720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65058390, states[0] = 15.639969, states[40]= 0.003527
Saving checkpoint... 
Iteration: 83894467, states[0] = -94.835145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 99851529, states[0] = -94.800481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 114492650, states[0] = -94.870882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 129927497, states[0] = -94.849315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145325253, states[0] = -94.769631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 157777221, states[0] = -94.690300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 173762448, states[0] = -94.656179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 185739562, states[0] = -94.591648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 199146690, states[0] = -45.375672, states[40]= 0.000225
Saving checkpoint... 
Iteration: 215286680, states[0] = -94.708702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229635075, states[0] = -35.401265, states[40]= 0.000809
Saving checkpoint... 
Iteration: 249289403, states[0] = -94.713631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260649106, states[0] = -47.537008, states[40]= 0.000165
Saving checkpoint... 
Iteration: 275317573, states[0] = -94.758428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 291093152, states[0] = -1.309529, states[40]= 0.004561
Saving checkpoint... 
Iteration: 304837183, states[0] = -94.782466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 323045704, states[0] = 20.444354, states[40]= 0.002554
Saving checkpoint... 
Iteration: 339444342, states[0] = -94.854303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 356992862, states[0] = -94.868396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 376580179, states[0] = 6.131803, states[40]= 0.004857
Saving checkpoint... 
Iteration: 394673693, states[0] = -72.879323, states[40]= 0.000003
Saving checkpoint... 
Iteration: 413476823, states[0] = -94.864262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 431410423, states[0] = -94.838935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450063644, states[0] = 13.645572, states[40]= 0.003964
Saving checkpoint... 
Iteration: 465023929, states[0] = 27.163965, states[40]= 0.001839
Saving checkpoint... 
Iteration: 485640347, states[0] = -39.833550, states[40]= 0.000476
Saving checkpoint... 
Iteration: 502404089, states[0] = -94.835241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 518798358, states[0] = -94.728346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535252203, states[0] = -94.627582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 549606036, states[0] = -11.144398, states[40]= 0.002481
Saving checkpoint... 
Iteration: 568346238, states[0] = -94.791026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 585470373, states[0] = -94.861831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603323025, states[0] = -94.764378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 623411532, states[0] = -94.838774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 639604913, states[0] = -10.193120, states[40]= 0.002688
Saving checkpoint... 
Iteration: 658028434, states[0] = 26.048488, states[40]= 0.001677
Saving checkpoint... 
Iteration: 676878840, states[0] = -94.818522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 691041948, states[0] = 21.761991, states[40]= 0.002296
Saving checkpoint... 
Iteration: 708073426, states[0] = 9.399741, states[40]= 0.004595
Saving checkpoint... 
Iteration: 724506374, states[0] = 29.635761, states[40]= 0.162149
Saving checkpoint... 
Iteration: 745224918, states[0] = -94.539480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 762181841, states[0] = -85.315771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 777978465, states[0] = -94.863296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 793514453, states[0] = 28.420232, states[40]= 0.011604
Saving checkpoint... 
Iteration: 812015330, states[0] = 28.385125, states[40]= 0.008931
Saving checkpoint... 
Iteration: 832998630, states[0] = -94.867823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 848322904, states[0] = -94.763278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861327982, states[0] = -94.769603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 877483496, states[0] = -94.864192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 892972333, states[0] = -94.861202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 910736820, states[0] = -94.579836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 930221262, states[0] = -94.525205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 942675952, states[0] = -76.084065, states[40]= 0.000002
Saving checkpoint... 
Iteration: 956042186, states[0] = 21.679880, states[40]= 0.002311
Saving checkpoint... 
Iteration: 973475260, states[0] = -94.861696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 991333044, states[0] = -94.775125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1003780057, states[0] = -94.692476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1007170944, states[0] = -69.326176, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1010162162, states[0] = -59.786779, states[40]= 0.000024
Saving checkpoint... 
Iteration: 1013855727, states[0] = -94.798426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016931637, states[0] = -94.846672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020149188, states[0] = -47.606261, states[40]= 0.000163
Saving checkpoint... 
Iteration: 1024527913, states[0] = 26.189639, states[40]= 0.001674
Saving checkpoint... 
Iteration: 1028095757, states[0] = -3.073879, states[40]= 0.004280
Saving checkpoint... 
Iteration: 1031803739, states[0] = -94.735140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1035446932, states[0] = -94.852579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1037933346, states[0] = -94.847306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1040750597, states[0] = -94.621129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1043833007, states[0] = -94.774880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047507745, states[0] = 28.820252, states[40]= 0.102788
Saving checkpoint... 
Iteration: 1050689994, states[0] = -93.052095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1054422633, states[0] = -94.842550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058514795, states[0] = 28.408889, states[40]= 0.010465
Saving checkpoint... 
Iteration: 1062532886, states[0] = 24.751117, states[40]= 0.001802
Saving checkpoint... 
Iteration: 1067090335, states[0] = 0.481146, states[40]= 0.004762
Saving checkpoint... 
Iteration: 1070206200, states[0] = -94.454518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073070480, states[0] = 10.733020, states[40]= 0.004431
Saving checkpoint... 
Iteration: 1076771470, states[0] = -94.673741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1080039606, states[0] = 22.565059, states[40]= 0.002149
Saving checkpoint... 
Iteration: 1084154629, states[0] = -52.595652, states[40]= 0.000077
Saving checkpoint... 
Iteration: 1088632134, states[0] = -32.962804, states[40]= 0.001037
Saving checkpoint... 
Iteration: 1091897834, states[0] = -94.829376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095011238, states[0] = 28.440173, states[40]= 0.032256
Saving checkpoint... 
Iteration: 1098728534, states[0] = -94.551052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1109743200, states[0] = -94.599156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1125129591, states[0] = -30.874570, states[40]= 0.001236
Saving checkpoint... 
Iteration: 1145346328, states[0] = -94.788896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1160120701, states[0] = -23.609595, states[40]= 0.001544
Saving checkpoint... 
Iteration: 1177652104, states[0] = -50.262963, states[40]= 0.000110
Saving checkpoint... 
Iteration: 1195548678, states[0] = 19.379738, states[40]= 0.002777
Saving checkpoint... 
Iteration: 1214141247, states[0] = -40.601346, states[40]= 0.000431
Saving checkpoint... 
Iteration: 1230568163, states[0] = 11.746960, states[40]= 0.004284
Saving checkpoint... 
Iteration: 1249305756, states[0] = -94.737461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1265025074, states[0] = 26.904833, states[40]= 0.001744
Saving checkpoint... 
Iteration: 1277281145, states[0] = -94.693635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291048405, states[0] = 19.478503, states[40]= 0.002756
Saving checkpoint... 
Iteration: 1305365477, states[0] = -94.805784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1319596766, states[0] = -3.788732, states[40]= 0.004146
Saving checkpoint... 
Iteration: 1335351737, states[0] = -94.793466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1347471469, states[0] = -94.859218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1361741051, states[0] = -94.591554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1376369598, states[0] = -94.808846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392519750, states[0] = 27.941430, states[40]= 0.003019
Saving checkpoint... 
Iteration: 1409065926, states[0] = 12.699597, states[40]= 0.004131
Saving checkpoint... 
Iteration: 1421827198, states[0] = -94.766482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437383681, states[0] = -94.819004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1452208609, states[0] = -94.468490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470449589, states[0] = -94.851857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489014329, states[0] = 28.424643, states[40]= 0.012051
Saving checkpoint... 
Iteration: 1504533294, states[0] = -95.275227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1520843884, states[0] = -94.830925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1537703210, states[0] = -94.761788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1553623109, states[0] = -20.408622, states[40]= 0.001547
Saving checkpoint... 
Iteration: 1568268480, states[0] = -94.370708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1584930653, states[0] = -94.491627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1600212600, states[0] = -94.537378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1618391823, states[0] = -94.469098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1641368508, states[0] = -94.439872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1658339299, states[0] = -94.441158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1674102093, states[0] = -94.424043, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -94.291336
 - CaMKt in component CaMK (millimolar): 0.001145
 - cass in component intracellular_ions (millimolar): 0.000087
 - nai in component intracellular_ions (millimolar): 6.337795
 - nass in component intracellular_ions (millimolar): 6.337882
 - ki in component intracellular_ions (millimolar): 145.558512
 - kss in component intracellular_ions (millimolar): 145.558501
 - cansr in component intracellular_ions (millimolar): 1.572406
 - cajsr in component intracellular_ions (millimolar): 1.572411
 - cai in component intracellular_ions (millimolar): 0.000090
 - m in component INa (dimensionless): 0.003849
 - hf in component INa (dimensionless): 0.868996
 - hs in component INa (dimensionless): 0.868996
 - j in component INa (dimensionless): 0.868997
 - hsp in component INa (dimensionless): 0.705449
 - jp in component INa (dimensionless): 0.868998
 - mL in component INaL (dimensionless): 0.000056
 - hL in component INaL (dimensionless): 0.712777
 - hLp in component INaL (dimensionless): 0.520134
 - a in component Ito (dimensionless): 0.000650
 - iF in component Ito (dimensionless): 0.999855
 - iS in component Ito (dimensionless): 0.997645
 - ap in component Ito (dimensionless): 0.000331
 - iFp in component Ito (dimensionless): 0.999855
 - iSp in component Ito (dimensionless): 0.999212
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998758
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003044
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.001914
 - xs1 in component IKs (dimensionless): 0.024367
 - xs2 in component IKs (dimensionless): 0.000094
 - xk1 in component IK1 (dimensionless): 0.997493
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
19:49:35 (99692): called boinc_finish(0)

</stderr_txt>
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