𝕏

Task 55724630

Name HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pueyo_APDR-conf_522_1
Workunit 26460553
Created 2 Jul 2024, 13:43:26 UTC
Sent 2 Jul 2024, 16:06:44 UTC
Report deadline 6 Jul 2024, 1:42:44 UTC
Received 5 Jul 2024, 23:05:47 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 238349
Run time 2 hours 57 min 8 sec
CPU time 2 hours 56 min 54 sec
Validate state Valid
Credit 57.45
Device peak FLOPS 3.83 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.25 MB
Peak swap size 3.82 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.16.6</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pueyo_APDR-conf_522.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pueyo_APDR-conf_522_1_r583476290_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pueyo_APDR-conf_522_1_r583476290_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 100.228860
     * GNaL_b in INaL: 0.005801
     * Gto_b in Ito: 0.083070
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032243
     * GKs_b in IKs: 0.001906
     * GK1_b in IK1: 0.161928
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 69.700184
     * GKb_b in IKb: 0.003813
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033011
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11891486, states[0] = -95.097627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23798964, states[0] = -95.019821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35675104, states[0] = -94.791912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47548222, states[0] = 11.826968, states[40]= 0.005015
Saving checkpoint... 
Iteration: 59416841, states[0] = -95.036220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 71300139, states[0] = -94.976853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83161688, states[0] = -92.109161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95039087, states[0] = 15.578084, states[40]= 0.005294
Saving checkpoint... 
Iteration: 106926472, states[0] = -95.024985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118957504, states[0] = -95.029920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130945011, states[0] = -95.026699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 142862008, states[0] = -95.001610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154741190, states[0] = -94.902598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166601264, states[0] = -21.194833, states[40]= 0.000891
Saving checkpoint... 
Iteration: 178509773, states[0] = 23.314518, states[40]= 0.055090
Saving checkpoint... 
Iteration: 190484171, states[0] = -95.031268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 202419174, states[0] = -95.019055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 214694982, states[0] = -94.820180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226942843, states[0] = -95.024172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 238911741, states[0] = -95.016946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 250934412, states[0] = -95.022344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 263250822, states[0] = -94.914443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275585274, states[0] = -6.680750, states[40]= 0.003043
Saving checkpoint... 
Iteration: 287923861, states[0] = -95.019891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 300145569, states[0] = -67.651844, states[40]= 0.000001
Saving checkpoint... 
Iteration: 312164180, states[0] = -93.174874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324044475, states[0] = 13.676536, states[40]= 0.005093
Saving checkpoint... 
Iteration: 336029576, states[0] = 18.830990, states[40]= 0.006136
Saving checkpoint... 
Iteration: 348362850, states[0] = -95.000303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 360699717, states[0] = -94.829723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 372833455, states[0] = -94.985997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384696413, states[0] = -94.822889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396854991, states[0] = -94.996834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 409100737, states[0] = -20.649206, states[40]= 0.000923
Saving checkpoint... 
Iteration: 420965022, states[0] = -95.027905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432827170, states[0] = -94.982338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 444710007, states[0] = -94.849885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 456591097, states[0] = -11.598259, states[40]= 0.002023
Saving checkpoint... 
Iteration: 468477782, states[0] = -95.029820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 480663469, states[0] = -92.816214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 492544135, states[0] = 13.804972, states[40]= 0.005102
Saving checkpoint... 
Iteration: 504426204, states[0] = -95.020281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516435420, states[0] = -95.022326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528315065, states[0] = -94.974646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540208677, states[0] = -94.847296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 552099453, states[0] = -19.425831, states[40]= 0.001006
Saving checkpoint... 
Iteration: 563949378, states[0] = -95.025087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 575833211, states[0] = -94.985728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 587715072, states[0] = -94.859168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599589853, states[0] = -10.491286, states[40]= 0.002237
Saving checkpoint... 
Iteration: 611455327, states[0] = -95.026141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 623337189, states[0] = -94.987882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635294771, states[0] = -94.959540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 647168034, states[0] = -94.263355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 659168992, states[0] = -94.392545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671048750, states[0] = 12.038486, states[40]= 0.005001
Saving checkpoint... 
Iteration: 682915228, states[0] = -95.017481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694790012, states[0] = -94.955510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706671065, states[0] = -94.572965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 718846022, states[0] = -94.992379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 731163341, states[0] = -92.744234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 743473136, states[0] = -95.028963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755802627, states[0] = -94.965648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 768115361, states[0] = -34.640365, states[40]= 0.000270
Saving checkpoint... 
Iteration: 780453071, states[0] = -95.025629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 792755561, states[0] = -94.919987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804731222, states[0] = -94.886257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 816645214, states[0] = -67.182032, states[40]= 0.000001
Saving checkpoint... 
Iteration: 828702767, states[0] = -94.835570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 841012734, states[0] = 22.583455, states[40]= 0.028348
Saving checkpoint... 
Iteration: 853102354, states[0] = -22.188844, states[40]= 0.000836
Saving checkpoint... 
Iteration: 864984875, states[0] = -95.030551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 876921339, states[0] = -95.018886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889127576, states[0] = -46.998701, states[40]= 0.000045
Saving checkpoint... 
Iteration: 900999508, states[0] = -95.032360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912872263, states[0] = -95.003727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 924747015, states[0] = -94.908994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 936723200, states[0] = -94.873156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 948613079, states[0] = -32.434287, states[40]= 0.000355
Saving checkpoint... 
Iteration: 960496515, states[0] = -95.031968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 972390590, states[0] = -95.010168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 984275221, states[0] = -94.941613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 996170214, states[0] = -94.511791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1008064751, states[0] = 5.350120, states[40]= 0.004741
Saving checkpoint... 
Iteration: 1020042079, states[0] = 14.573778, states[40]= 0.005168
Saving checkpoint... 
Iteration: 1031911848, states[0] = -95.016374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044054325, states[0] = 9.825763, states[40]= 0.004921
Saving checkpoint... 
Iteration: 1056356111, states[0] = -94.996917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1068551931, states[0] = 10.787656, states[40]= 0.004953
Saving checkpoint... 
Iteration: 1080562525, states[0] = 6.354792, states[40]= 0.004794
Saving checkpoint... 
Iteration: 1092677739, states[0] = -94.758389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1104952657, states[0] = -95.025346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1117047538, states[0] = 12.507823, states[40]= 0.005023
Saving checkpoint... 
Iteration: 1129052833, states[0] = 10.427465, states[40]= 0.004941
Saving checkpoint... 
Iteration: 1140986501, states[0] = -95.030591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1152861113, states[0] = -94.999047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1164800963, states[0] = -94.964116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1176684695, states[0] = -94.794907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1188561615, states[0] = 6.756569, states[40]= 0.004812
Saving checkpoint... 
Iteration: 1200437377, states[0] = -95.022302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1212339346, states[0] = -94.988654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1224346163, states[0] = -94.992125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1236233319, states[0] = -94.889219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1248116052, states[0] = -35.311724, states[40]= 0.000247
Saving checkpoint... 
Iteration: 1259988367, states[0] = -95.030759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1271922032, states[0] = -95.018802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1283915783, states[0] = -95.017240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1295794897, states[0] = -94.959220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1307675089, states[0] = -94.721092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1319557844, states[0] = 8.374031, states[40]= 0.004874
Saving checkpoint... 
Iteration: 1331441251, states[0] = -95.023015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1343329448, states[0] = -94.983092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355210676, states[0] = -94.850559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367487790, states[0] = -95.030616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1379373730, states[0] = -95.003990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1391582786, states[0] = -4.810264, states[40]= 0.003435
Saving checkpoint... 
Iteration: 1403603075, states[0] = -22.874899, states[40]= 0.000801
Saving checkpoint... 
Iteration: 1415885261, states[0] = -95.008114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1428152682, states[0] = -78.330660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1440493261, states[0] = -95.031265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1452808418, states[0] = -94.969460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1465150251, states[0] = -74.370161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1477212710, states[0] = -94.854272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489092095, states[0] = -12.502638, states[40]= 0.001858
Saving checkpoint... 
Iteration: 1501270235, states[0] = -3.678445, states[40]= 0.003956
Saving checkpoint... 
Iteration: 1513543760, states[0] = 11.389829, states[40]= 0.005840
Saving checkpoint... 
Iteration: 1525739892, states[0] = -95.228092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1537591610, states[0] = -28.123056, states[40]= 0.000546
Saving checkpoint... 
Iteration: 1549476449, states[0] = -95.281718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1561296324, states[0] = -33.944102, states[40]= 0.000293
Saving checkpoint... 
Iteration: 1573257021, states[0] = 3.451750, states[40]= 0.005224
Saving checkpoint... 
Iteration: 1585111036, states[0] = -95.214662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1596957550, states[0] = 3.040888, states[40]= 0.005185
Saving checkpoint... 
Iteration: 1608793562, states[0] = -95.185172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1620632368, states[0] = 16.108200, states[40]= 0.006741
Saving checkpoint... 
Iteration: 1632482643, states[0] = -95.163030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1644330348, states[0] = 16.971629, states[40]= 0.007017
Saving checkpoint... 
Iteration: 1656346782, states[0] = 9.087226, states[40]= 0.005714
Saving checkpoint... 
Iteration: 1668195390, states[0] = -95.190806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1680409169, states[0] = -49.343873, states[40]= 0.000033
Saving checkpoint... 
Iteration: 1692703105, states[0] = -42.159272, states[40]= 0.000096
Saving checkpoint... 
Iteration: 1705006556, states[0] = -46.209737, states[40]= 0.000053
Saving checkpoint... 
Iteration: 1717280339, states[0] = -16.924999, states[40]= 0.001377
Saving checkpoint... 
Iteration: 1729326344, states[0] = -72.300830, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1741176066, states[0] = -95.296969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1753012113, states[0] = -52.961814, states[40]= 0.000018
Saving checkpoint... 
Iteration: 1765014864, states[0] = -56.389806, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1776850717, states[0] = -95.273156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1788701279, states[0] = -40.075155, states[40]= 0.000130
Saving checkpoint... 
Iteration: 1800553905, states[0] = 8.455774, states[40]= 0.004977
Saving checkpoint... 
Iteration: 1812738017, states[0] = -94.941126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1824582512, states[0] = -6.021230, states[40]= 0.003218
Saving checkpoint... 
Iteration: 1836431387, states[0] = -95.045020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1848265291, states[0] = -94.948086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1860122674, states[0] = -42.697077, states[40]= 0.000086
Saving checkpoint... 
Iteration: 1871951455, states[0] = -95.033176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1883788934, states[0] = -94.959891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1895638081, states[0] = -58.882822, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1907463633, states[0] = -95.029701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1919295021, states[0] = -94.961027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1931103340, states[0] = -23.213793, states[40]= 0.000785
Saving checkpoint... 
Iteration: 1942912258, states[0] = -95.016918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1954721084, states[0] = -94.869623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1966550742, states[0] = 11.249638, states[40]= 0.004969
Saving checkpoint... 
Iteration: 1978370706, states[0] = -95.002767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1990187455, states[0] = -94.802112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2002014374, states[0] = 22.296046, states[40]= 0.020541
Saving checkpoint... 
Iteration: 2013888972, states[0] = -95.009052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2025775801, states[0] = -94.941562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2037908510, states[0] = -95.014841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2050186175, states[0] = -94.798532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2062474897, states[0] = -95.028358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2074376629, states[0] = -95.004597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2086217414, states[0] = -94.862364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2098051096, states[0] = 11.118892, states[40]= 0.004964
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.907482
 - CaMKt in component CaMK (millimolar): 0.006954
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.588484
 - nass in component intracellular_ions (millimolar): 6.588544
 - ki in component intracellular_ions (millimolar): 145.389210
 - kss in component intracellular_ions (millimolar): 145.389191
 - cansr in component intracellular_ions (millimolar): 1.311247
 - cajsr in component intracellular_ions (millimolar): 1.273359
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003616
 - hf in component INa (dimensionless): 0.880098
 - hs in component INa (dimensionless): 0.880094
 - j in component INa (dimensionless): 0.880065
 - hsp in component INa (dimensionless): 0.726014
 - jp in component INa (dimensionless): 0.880045
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.710232
 - hLp in component INaL (dimensionless): 0.452661
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.622016
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.697022
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935609
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999887
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001600
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.328924
 - xs1 in component IKs (dimensionless): 0.240514
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997336
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
00:57:43 (214754): called boinc_finish(0)

</stderr_txt>
]]>


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