𝕏

Task 55722875

Name HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_MID_3000-conf_718_0
Workunit 26459676
Created 2 Jul 2024, 13:42:34 UTC
Sent 2 Jul 2024, 15:50:56 UTC
Report deadline 5 Jul 2024, 15:50:56 UTC
Received 4 Jul 2024, 3:17:01 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 197686
Run time 2 hours 18 min 42 sec
CPU time 6 min 15 sec
Validate state Valid
Credit 44.51
Device peak FLOPS 3.02 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 6.79 MB
Peak swap size 1.39 MB
Peak disk usage 0.02 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_MID_3000-conf_718.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_MID_3000-conf_718_0_r1147229977_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_MID_3000-conf_718_0_r1147229977_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.250864
     * GNaL_b in INaL: 0.006171
     * Gto_b in Ito: 0.082125
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031702
     * GKs_b in IKs: 0.001914
     * GK1_b in IK1: 0.159468
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 71.054661
     * GKb_b in IKb: 0.003777
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031427
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12152078, states[0] = 1.604999, states[40]= 0.000237
Saving checkpoint... 
Iteration: 24312549, states[0] = -92.882950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 36445063, states[0] = -94.058255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48624599, states[0] = -94.194916, states[40]= 0.000001
Saving checkpoint... 
Iteration: 60837577, states[0] = -94.222104, states[40]= 0.000001
Saving checkpoint... 
Iteration: 73090758, states[0] = -94.222160, states[40]= 0.000001
Saving checkpoint... 
Iteration: 85276181, states[0] = -94.221063, states[40]= 0.000001
Saving checkpoint... 
Iteration: 97504104, states[0] = 21.189699, states[40]= 0.779018


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_MID_3000-conf_718.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_MID_3000-conf_718_0_r1147229977_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_MID_3000-conf_718_0_r1147229977_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.250864
     * GNaL_b in INaL: 0.006171
     * Gto_b in Ito: 0.082125
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031702
     * GKs_b in IKs: 0.001914
     * GK1_b in IK1: 0.159468
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 71.054661
     * GKb_b in IKb: 0.003777
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031427
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 1000.000000
     * CL_0 in membrane: 3000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 97504104
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 21.189699 (After loading)
 - states[40]: 0.779018 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 109510172, states[0] = 29.650209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121518533, states[0] = 32.980334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133598079, states[0] = 15.781596, states[40]= 0.000017
Saving checkpoint... 
Iteration: 145676421, states[0] = -19.919748, states[40]= 0.003047
Saving checkpoint... 
Iteration: 157761612, states[0] = -73.669310, states[40]= 0.000021
Saving checkpoint... 
Iteration: 169876501, states[0] = -94.006040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 181966377, states[0] = -94.157858, states[40]= 0.000001
Saving checkpoint... 
Iteration: 194023068, states[0] = -94.202788, states[40]= 0.000001
Saving checkpoint... 
Iteration: 206092898, states[0] = -94.232457, states[40]= 0.000001
Saving checkpoint... 
Iteration: 218177149, states[0] = -94.248474, states[40]= 0.000001
Saving checkpoint... 
Iteration: 230243181, states[0] = -94.253149, states[40]= 0.000001
Saving checkpoint... 
Iteration: 242270336, states[0] = -94.253826, states[40]= 0.000001
Saving checkpoint... 
Iteration: 254300145, states[0] = -94.254001, states[40]= 0.000001
Saving checkpoint... 
Iteration: 266464639, states[0] = -94.250016, states[40]= 0.000001
Saving checkpoint... 
Iteration: 278628045, states[0] = -94.242981, states[40]= 0.000001
Saving checkpoint... 
Iteration: 290800885, states[0] = -94.235747, states[40]= 0.000001
Saving checkpoint... 
Iteration: 302909218, states[0] = -94.231661, states[40]= 0.000001
Saving checkpoint... 
Iteration: 314917550, states[0] = -94.231180, states[40]= 0.000001
Saving checkpoint... 
Iteration: 327015210, states[0] = 32.011972, states[40]= -0.000000
Saving checkpoint... 
Iteration: 339143022, states[0] = -2.449431, states[40]= 0.000587
Saving checkpoint... 
Iteration: 351216295, states[0] = -37.344524, states[40]= 0.003517
Saving checkpoint... 
Iteration: 363299665, states[0] = -93.699041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 375421825, states[0] = -94.098397, states[40]= 0.000001
Saving checkpoint... 
Iteration: 387472177, states[0] = -94.161671, states[40]= 0.000001
Saving checkpoint... 
Iteration: 399579015, states[0] = -94.225424, states[40]= 0.000001
Saving checkpoint... 
Iteration: 411720086, states[0] = -94.249134, states[40]= 0.000001
Saving checkpoint... 
Iteration: 423837318, states[0] = -94.250919, states[40]= 0.000001
Saving checkpoint... 
Iteration: 435954190, states[0] = -94.247482, states[40]= 0.000001
Saving checkpoint... 
Iteration: 448083714, states[0] = -94.241915, states[40]= 0.000001
Saving checkpoint... 
Iteration: 460162940, states[0] = -94.238301, states[40]= 0.000001
Saving checkpoint... 
Iteration: 472223984, states[0] = -94.235549, states[40]= 0.000001
Saving checkpoint... 
Iteration: 484299559, states[0] = -94.232358, states[40]= 0.000001
Saving checkpoint... 
Iteration: 496387103, states[0] = -94.228955, states[40]= 0.000001
Saving checkpoint... 
Iteration: 508565454, states[0] = 27.392722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 520661208, states[0] = -12.372460, states[40]= 0.000932
Saving checkpoint... 
Iteration: 532762687, states[0] = -76.616060, states[40]= 0.000014
Saving checkpoint... 
Iteration: 544812202, states[0] = -93.763618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556852258, states[0] = -93.930483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 568735730, states[0] = -50.707021, states[40]= 0.000672
Saving checkpoint... 
Iteration: 580561979, states[0] = 28.480911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592479878, states[0] = -94.224151, states[40]= 0.000001
Saving checkpoint... 
Iteration: 604426415, states[0] = -94.225651, states[40]= 0.000001
Saving checkpoint... 
Iteration: 616385781, states[0] = -94.226816, states[40]= 0.000001
Saving checkpoint... 
Iteration: 628362537, states[0] = -94.227420, states[40]= 0.000001
Saving checkpoint... 
Iteration: 640309287, states[0] = -94.229154, states[40]= 0.000001
Saving checkpoint... 
Iteration: 652229507, states[0] = -94.232057, states[40]= 0.000001
Saving checkpoint... 
Iteration: 664110243, states[0] = -94.236847, states[40]= 0.000001
Saving checkpoint... 
Iteration: 676008083, states[0] = -94.240988, states[40]= 0.000001
Saving checkpoint... 
Iteration: 687965860, states[0] = -94.242463, states[40]= 0.000001
Saving checkpoint... 
Iteration: 699938726, states[0] = -94.243250, states[40]= 0.000001
Saving checkpoint... 
Iteration: 711886499, states[0] = -94.244682, states[40]= 0.000001
Saving checkpoint... 
Iteration: 723852562, states[0] = -94.245235, states[40]= 0.000001
Saving checkpoint... 
Iteration: 735773577, states[0] = -94.245214, states[40]= 0.000001
Saving checkpoint... 
Iteration: 747704946, states[0] = -94.242009, states[40]= 0.000001
Saving checkpoint... 
Iteration: 759694012, states[0] = -94.240894, states[40]= 0.000001
Saving checkpoint... 
Iteration: 771637523, states[0] = -94.233317, states[40]= 0.000001
Saving checkpoint... 
Iteration: 783450758, states[0] = -94.131269, states[40]= 0.000001
Saving checkpoint... 
Iteration: 795514818, states[0] = -94.187975, states[40]= 0.000001
Saving checkpoint... 
Iteration: 807614158, states[0] = -94.227877, states[40]= 0.000001
Saving checkpoint... 
Iteration: 819685840, states[0] = -94.239035, states[40]= 0.000001
Saving checkpoint... 
Iteration: 831763235, states[0] = -94.243255, states[40]= 0.000001
Saving checkpoint... 
Iteration: 843788068, states[0] = -94.243435, states[40]= 0.000001
Saving checkpoint... 
Iteration: 855882908, states[0] = -94.242157, states[40]= 0.000001
Saving checkpoint... 
Iteration: 867928803, states[0] = -94.240540, states[40]= 0.000001
Saving checkpoint... 
Iteration: 879967675, states[0] = -94.238896, states[40]= 0.000001
Saving checkpoint... 
Iteration: 891996872, states[0] = -94.237518, states[40]= 0.000001
Saving checkpoint... 
Iteration: 904076880, states[0] = -94.233916, states[40]= 0.000001
Saving checkpoint... 
Iteration: 916162455, states[0] = -94.230026, states[40]= 0.000001
Saving checkpoint... 
Iteration: 927956731, states[0] = -94.238440, states[40]= 0.000001
Saving checkpoint... 
Iteration: 939743834, states[0] = -94.240692, states[40]= 0.000001
Saving checkpoint... 
Iteration: 951625526, states[0] = -94.227734, states[40]= 0.000001
Saving checkpoint... 
Iteration: 963526359, states[0] = -94.191855, states[40]= 0.000001
Saving checkpoint... 
Iteration: 975195233, states[0] = -27.045699, states[40]= 0.006949
Saving checkpoint... 
Iteration: 987080212, states[0] = 22.313204, states[40]= 0.000003
Saving checkpoint... 
Iteration: 999261057, states[0] = -74.132741, states[40]= 0.000020
Saving checkpoint... 
Iteration: 1011507512, states[0] = -94.179201, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1023707003, states[0] = -94.237140, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1035924094, states[0] = -94.237643, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1048149979, states[0] = -94.228153, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1060336640, states[0] = -94.220487, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1072503837, states[0] = 20.679881, states[40]= 0.910882
Saving checkpoint... 
Iteration: 1084711938, states[0] = -34.803760, states[40]= 0.004511
Saving checkpoint... 
Iteration: 1096926702, states[0] = -94.092816, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1109081718, states[0] = -94.213405, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1121268106, states[0] = -94.238103, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1133461524, states[0] = -94.234528, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1145649204, states[0] = -94.226419, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1157855066, states[0] = -94.218050, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1170055008, states[0] = 30.474936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182287227, states[0] = -93.590943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1194446893, states[0] = -94.119003, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1206542418, states[0] = -94.195870, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1218496987, states[0] = -94.167837, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1230476197, states[0] = -94.150083, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1242404347, states[0] = -94.051629, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1254462661, states[0] = -94.136128, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1266529880, states[0] = -94.188301, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1278609327, states[0] = -94.218150, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1290768545, states[0] = -94.235027, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1302859195, states[0] = -94.234581, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1314958921, states[0] = -94.231323, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1327038474, states[0] = -94.227870, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1339100081, states[0] = -94.225003, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1351221606, states[0] = -94.219656, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1363303753, states[0] = -94.216202, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1375400228, states[0] = -94.212502, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1387472379, states[0] = -94.209913, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1399460601, states[0] = -94.210069, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1411425564, states[0] = -94.210991, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1423404466, states[0] = -94.211482, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1435375883, states[0] = -94.212256, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1447383260, states[0] = -94.211777, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1459464618, states[0] = -94.208847, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1471552310, states[0] = 31.162436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483538544, states[0] = 33.657808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1495573216, states[0] = 24.801864, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.082967
 - CaMKt in component CaMK (millimolar): 0.004504
 - cass in component intracellular_ions (millimolar): 0.000099
 - nai in component intracellular_ions (millimolar): 7.933420
 - nass in component intracellular_ions (millimolar): 7.933584
 - ki in component intracellular_ions (millimolar): 143.783547
 - kss in component intracellular_ions (millimolar): 143.783528
 - cansr in component intracellular_ions (millimolar): 1.927238
 - cajsr in component intracellular_ions (millimolar): 1.929487
 - cai in component intracellular_ions (millimolar): 0.000104
 - m in component INa (dimensionless): 0.003930
 - hf in component INa (dimensionless): 0.865049
 - hs in component INa (dimensionless): 0.865050
 - j in component INa (dimensionless): 0.865057
 - hsp in component INa (dimensionless): 0.698291
 - jp in component INa (dimensionless): 0.865061
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.707122
 - hLp in component INaL (dimensionless): 0.508377
 - a in component Ito (dimensionless): 0.000659
 - iF in component Ito (dimensionless): 0.999850
 - iS in component Ito (dimensionless): 0.963664
 - ap in component Ito (dimensionless): 0.000336
 - iFp in component Ito (dimensionless): 0.999850
 - iSp in component Ito (dimensionless): 0.980949
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.985518
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004850
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.034620
 - xs1 in component IKs (dimensionless): 0.094138
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997544
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
23:03:19 (16168): called boinc_finish(0)

</stderr_txt>
]]>


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