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Task 55720683

Name HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pieske_333-conf_414_0
Workunit 26458581
Created 2 Jul 2024, 13:41:22 UTC
Sent 2 Jul 2024, 15:33:30 UTC
Report deadline 5 Jul 2024, 15:33:30 UTC
Received 4 Jul 2024, 14:34:52 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 233543
Run time 1 hours 0 min 38 sec
CPU time 42 min 52 sec
Validate state Valid
Credit 44.32
Device peak FLOPS 5.61 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 3.11 MB
Peak swap size 391.91 GB
Peak disk usage 0.13 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pieske_333-conf_414.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pieske_333-conf_414_0_r16953423_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Pieske_333-conf_414_0_r16953423_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.248477
     * GNaL_b in INaL: 0.005593
     * Gto_b in Ito: 0.085478
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031496
     * GKs_b in IKs: 0.001887
     * GK1_b in IK1: 0.163703
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 69.431360
     * GKb_b in IKb: 0.003816
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029230
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 17783577, states[0] = -87.463045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 45528046, states[0] = 11.610153, states[40]= 0.007800
Saving checkpoint... 
Iteration: 72666694, states[0] = 24.307399, states[40]= 0.083005
Saving checkpoint... 
Iteration: 100657569, states[0] = 40.841608, states[40]= 0.025947
Saving checkpoint... 
Iteration: 129501448, states[0] = 20.790664, states[40]= 0.020678
Saving checkpoint... 
Iteration: 160816318, states[0] = -87.792066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 190312726, states[0] = -87.790395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 223523415, states[0] = 1.593926, states[40]= 0.006374
Saving checkpoint... 
Iteration: 250359320, states[0] = -3.646469, states[40]= 0.005173
Saving checkpoint... 
Iteration: 279679021, states[0] = 6.093290, states[40]= 0.007065
Saving checkpoint... 
Iteration: 306031412, states[0] = -18.115628, states[40]= 0.001522
Saving checkpoint... 
Iteration: 337696845, states[0] = -20.851475, states[40]= 0.001181
Saving checkpoint... 
Iteration: 365040525, states[0] = -38.957564, states[40]= 0.000188
Saving checkpoint... 
Iteration: 397089621, states[0] = -87.660458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 428356050, states[0] = -23.110867, states[40]= 0.000970
Saving checkpoint... 
Iteration: 453180817, states[0] = -14.516262, states[40]= 0.002164
Saving checkpoint... 
Iteration: 481465591, states[0] = 21.036393, states[40]= 0.022979
Saving checkpoint... 
Iteration: 513283829, states[0] = 40.113535, states[40]= 0.077895
Saving checkpoint... 
Iteration: 545011319, states[0] = -23.491614, states[40]= 0.000939
Saving checkpoint... 
Iteration: 571351368, states[0] = -36.421892, states[40]= 0.000259
Saving checkpoint... 
Iteration: 594037261, states[0] = -67.527574, states[40]= 0.000003
Saving checkpoint... 
Iteration: 613869667, states[0] = -69.312528, states[40]= 0.000002
Saving checkpoint... 
Iteration: 633968792, states[0] = 11.757017, states[40]= 0.007836
Saving checkpoint... 
Iteration: 651261204, states[0] = -87.774600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 676027864, states[0] = -65.564420, states[40]= 0.000004
Saving checkpoint... 
Iteration: 697267990, states[0] = 29.015945, states[40]= 0.127737
Saving checkpoint... 
Iteration: 722936039, states[0] = 23.475038, states[40]= 0.067038
Saving checkpoint... 
Iteration: 746386717, states[0] = -87.652011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 771977321, states[0] = -7.823724, states[40]= 0.003947
Saving checkpoint... 
Iteration: 796424776, states[0] = 28.917957, states[40]= 0.127481
Saving checkpoint... 
Iteration: 826512040, states[0] = -64.314217, states[40]= 0.000004
Saving checkpoint... 
Iteration: 856400794, states[0] = -87.754134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 882785630, states[0] = 5.896021, states[40]= 0.007038
Saving checkpoint... 
Iteration: 914043440, states[0] = -87.686769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 944784544, states[0] = 1.658223, states[40]= 0.006386
Saving checkpoint... 
Iteration: 971143642, states[0] = -34.945759, states[40]= 0.000310
Saving checkpoint... 
Iteration: 1000298963, states[0] = -23.268488, states[40]= 0.000957
Saving checkpoint... 
Iteration: 1030517356, states[0] = -87.552418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1060845101, states[0] = -87.453752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093067783, states[0] = 22.347614, states[40]= 0.043036
Saving checkpoint... 
Iteration: 1120055679, states[0] = 41.204835, states[40]= 0.030144
Saving checkpoint... 
Iteration: 1152329045, states[0] = -86.267035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182420890, states[0] = 6.984137, states[40]= 0.007181
Saving checkpoint... 
Iteration: 1204879727, states[0] = -59.837778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232893125, states[0] = 19.997110, states[40]= 0.015639
Saving checkpoint... 
Iteration: 1262227335, states[0] = 18.355982, states[40]= 0.011081
Saving checkpoint... 
Iteration: 1286192232, states[0] = -87.757081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1310154507, states[0] = -87.500690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340269271, states[0] = -29.279521, states[40]= 0.000565
Saving checkpoint... 
Iteration: 1363387219, states[0] = 16.729153, states[40]= 0.009411
Saving checkpoint... 
Iteration: 1379469138, states[0] = -83.748776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401959380, states[0] = -72.520589, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1424577364, states[0] = -6.135177, states[40]= 0.004455
Saving checkpoint... 
Iteration: 1446533860, states[0] = 21.755182, states[40]= 0.032282
Saving checkpoint... 
Iteration: 1472352930, states[0] = -65.636361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497598107, states[0] = -44.697034, states[40]= 0.000085
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -87.668465
 - CaMKt in component CaMK (millimolar): 0.043503
 - cass in component intracellular_ions (millimolar): 0.000116
 - nai in component intracellular_ions (millimolar): 7.039520
 - nass in component intracellular_ions (millimolar): 7.039668
 - ki in component intracellular_ions (millimolar): 144.877905
 - kss in component intracellular_ions (millimolar): 144.877873
 - cansr in component intracellular_ions (millimolar): 1.632839
 - cajsr in component intracellular_ions (millimolar): 1.195335
 - cai in component intracellular_ions (millimolar): 0.000112
 - m in component INa (dimensionless): 0.007500
 - hf in component INa (dimensionless): 0.690815
 - hs in component INa (dimensionless): 0.690573
 - j in component INa (dimensionless): 0.679716
 - hsp in component INa (dimensionless): 0.445408
 - jp in component INa (dimensionless): 0.652756
 - mL in component INaL (dimensionless): 0.000196
 - hL in component INaL (dimensionless): 0.290671
 - hLp in component INaL (dimensionless): 0.134747
 - a in component Ito (dimensionless): 0.001015
 - iF in component Ito (dimensionless): 0.999537
 - iS in component Ito (dimensionless): 0.174846
 - ap in component Ito (dimensionless): 0.000517
 - iFp in component Ito (dimensionless): 0.999537
 - iSp in component Ito (dimensionless): 0.211365
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.803493
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.966602
 - jca in component ICaL (dimensionless): 0.947671
 - ffp in component ICaL (dimensionless): 0.999858
 - fcafp in component ICaL (dimensionless): 0.999991
 - nca in component ICaL (dimensionless): 0.009604
 - xrf in component IKr (dimensionless): 0.029342
 - xrs in component IKr (dimensionless): 0.789243
 - xs1 in component IKs (dimensionless): 0.459646
 - xs2 in component IKs (dimensionless): 0.001226
 - xk1 in component IK1 (dimensionless): 0.996820
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
15:56:36 (49991): called boinc_finish(0)

</stderr_txt>
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