𝕏

Task 55716818

Name HuVeMOp_20240702153647868011_ORdGradInc_k_26-Schmidt_666-conf_607_0
Workunit 26456654
Created 2 Jul 2024, 13:39:18 UTC
Sent 2 Jul 2024, 15:08:21 UTC
Report deadline 5 Jul 2024, 15:08:25 UTC
Received 3 Jul 2024, 6:36:57 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 227233
Run time 3 hours 18 min 51 sec
CPU time 1 hours 38 min 22 sec
Validate state Valid
Credit 45.96
Device peak FLOPS 3.36 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.48 MB
Peak swap size 391.72 GB
Peak disk usage 0.23 MB

Stderr output

<core_client_version>7.20.7</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Schmidt_666-conf_607.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Schmidt_666-conf_607_0_r1268139556_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Schmidt_666-conf_607_0_r1268139556_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000150.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.399020
     * GNaL_b in INaL: 0.005637
     * Gto_b in Ito: 0.085414
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032150
     * GKs_b in IKs: 0.001935
     * GK1_b in IK1: 0.164386
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 71.033519
     * GKb_b in IKb: 0.003769
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032784
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 4500.000000
     * CL_0 in membrane: 666.700000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499741650.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 16424464, states[0] = -8.182917, states[40]= 0.000513
Saving checkpoint... 
Iteration: 32889282, states[0] = -84.399280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 49056087, states[0] = 16.652170, states[40]= 0.000034
Saving checkpoint... 
Iteration: 65276902, states[0] = -84.620275, states[40]= 0.000001
Saving checkpoint... 
Iteration: 81313989, states[0] = -84.706345, states[40]= 0.000001
Saving checkpoint... 
Iteration: 97486524, states[0] = -75.796176, states[40]= 0.000001
Saving checkpoint... 
Iteration: 113862675, states[0] = -84.187684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130225842, states[0] = -84.390382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 146537944, states[0] = -84.242001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 162844258, states[0] = -83.947467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 179158506, states[0] = -77.248890, states[40]= 0.000001
Saving checkpoint... 
Iteration: 195419466, states[0] = 3.263578, states[40]= 0.000212
Saving checkpoint... 
Iteration: 211652329, states[0] = -84.701510, states[40]= 0.000001
Saving checkpoint... 
Iteration: 227882387, states[0] = -84.291918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244069846, states[0] = 14.485078, states[40]= 0.000048
Saving checkpoint... 
Iteration: 260297704, states[0] = -84.648055, states[40]= 0.000001
Saving checkpoint... 
Iteration: 276797457, states[0] = -38.651043, states[40]= 0.000101
Saving checkpoint... 
Iteration: 292912213, states[0] = -84.449956, states[40]= 0.000001
Saving checkpoint... 
Iteration: 309030507, states[0] = 31.599193, states[40]= 0.010200
Saving checkpoint... 
Iteration: 325427785, states[0] = 1.995175, states[40]= 0.000238
Saving checkpoint... 
Iteration: 341568322, states[0] = -84.377580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357776247, states[0] = -10.098871, states[40]= 0.000304
Saving checkpoint... 
Iteration: 374073698, states[0] = 15.909357, states[40]= 0.000038
Saving checkpoint... 
Iteration: 390310233, states[0] = -84.659962, states[40]= 0.000001
Saving checkpoint... 
Iteration: 406622314, states[0] = -84.599370, states[40]= 0.000001
Saving checkpoint... 
Iteration: 423020220, states[0] = -84.736454, states[40]= 0.000001
Saving checkpoint... 
Iteration: 439080888, states[0] = 13.781329, states[40]= 0.000054
Saving checkpoint... 
Iteration: 455193141, states[0] = -83.961240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 471652115, states[0] = -84.668556, states[40]= 0.000001
Saving checkpoint... 
Iteration: 487881685, states[0] = -84.181784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 504061906, states[0] = 24.927255, states[40]= 0.000011
Saving checkpoint... 
Iteration: 520308768, states[0] = -84.637254, states[40]= 0.000001
Saving checkpoint... 
Iteration: 536889573, states[0] = -84.224166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553244066, states[0] = -84.363655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 569476183, states[0] = -35.825028, states[40]= 0.000128
Saving checkpoint... 
Iteration: 585841078, states[0] = -71.717656, states[40]= 0.000001
Saving checkpoint... 
Iteration: 602062591, states[0] = 26.770869, states[40]= 0.000025
Saving checkpoint... 
Iteration: 618516893, states[0] = -80.123285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635034191, states[0] = 34.830718, states[40]= 0.867019
Saving checkpoint... 
Iteration: 651257208, states[0] = -84.409092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 667632262, states[0] = -84.583749, states[40]= 0.000001
Saving checkpoint... 
Iteration: 684068994, states[0] = 25.778808, states[40]= 0.000014
Saving checkpoint... 
Iteration: 700283238, states[0] = -84.519727, states[40]= 0.000001
Saving checkpoint... 
Iteration: 716569255, states[0] = -84.250363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 732835554, states[0] = -55.603375, states[40]= 0.000014
Saving checkpoint... 
Iteration: 748788660, states[0] = -2.992686, states[40]= 0.000318
Saving checkpoint... 
Iteration: 764902455, states[0] = -84.230181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 781277145, states[0] = -84.473879, states[40]= 0.000001
Saving checkpoint... 
Iteration: 797431435, states[0] = 14.169556, states[40]= 0.000050
Saving checkpoint... 
Iteration: 813989127, states[0] = -84.628047, states[40]= 0.000001
Saving checkpoint... 
Iteration: 830336921, states[0] = -84.661050, states[40]= 0.000001
Saving checkpoint... 
Iteration: 846576104, states[0] = -84.250037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 862961206, states[0] = -84.528736, states[40]= 0.000001
Saving checkpoint... 
Iteration: 879453034, states[0] = 3.702621, states[40]= 0.000203
Saving checkpoint... 
Iteration: 896106941, states[0] = 12.003214, states[40]= 0.000071
Saving checkpoint... 
Iteration: 912252771, states[0] = -84.295790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 928636129, states[0] = -84.546084, states[40]= 0.000001
Saving checkpoint... 
Iteration: 944986581, states[0] = -84.599657, states[40]= 0.000001
Saving checkpoint... 
Iteration: 961344617, states[0] = -84.660710, states[40]= 0.000001
Saving checkpoint... 
Iteration: 977934022, states[0] = -84.366362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 994003513, states[0] = -84.637899, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1010605864, states[0] = -84.385996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1026806187, states[0] = -6.372797, states[40]= 0.000331
Saving checkpoint... 
Iteration: 1043158238, states[0] = -26.623576, states[40]= 0.000189
Saving checkpoint... 
Iteration: 1059425846, states[0] = 23.629422, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1075818086, states[0] = -16.922708, states[40]= 0.000218
Saving checkpoint... 
Iteration: 1092005818, states[0] = -84.629359, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1108326184, states[0] = -84.590279, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1124524431, states[0] = -58.650496, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1140810558, states[0] = -5.076394, states[40]= 0.000328
Saving checkpoint... 
Iteration: 1157052190, states[0] = -84.713452, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1173618029, states[0] = -84.404646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1190127090, states[0] = 8.848048, states[40]= 0.000110
Saving checkpoint... 
Iteration: 1206337957, states[0] = -84.608331, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1222445861, states[0] = 17.797514, states[40]= 0.000027
Saving checkpoint... 
Iteration: 1238602188, states[0] = -84.286906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254862614, states[0] = -56.690972, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1270885609, states[0] = -81.804414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287127385, states[0] = 11.499764, states[40]= 0.000076
Saving checkpoint... 
Iteration: 1303436631, states[0] = 24.288276, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1319768661, states[0] = 25.245841, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1336162221, states[0] = -14.324079, states[40]= 0.000249
Saving checkpoint... 
Iteration: 1352523586, states[0] = -44.825912, states[40]= 0.000053
Saving checkpoint... 
Iteration: 1369077171, states[0] = 30.438779, states[40]= 0.097308
Saving checkpoint... 
Iteration: 1385530871, states[0] = -51.066575, states[40]= 0.000025
Saving checkpoint... 
Iteration: 1401734969, states[0] = -84.713715, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1418220298, states[0] = -76.980486, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1434581271, states[0] = -84.026395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450897602, states[0] = -82.873496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1467373913, states[0] = -84.658072, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1483988722, states[0] = -84.500695, states[40]= 0.000001
Total time: 3000150.000000
State Variables:
 - v in component membrane (millivolt): -84.589874
 - CaMKt in component CaMK (millimolar): 0.038574
 - cass in component intracellular_ions (millimolar): 0.000103
 - nai in component intracellular_ions (millimolar): 6.798996
 - nass in component intracellular_ions (millimolar): 6.799151
 - ki in component intracellular_ions (millimolar): 144.868429
 - kss in component intracellular_ions (millimolar): 144.868401
 - cansr in component intracellular_ions (millimolar): 2.045296
 - cajsr in component intracellular_ions (millimolar): 1.800940
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.010217
 - hf in component INa (dimensionless): 0.573968
 - hs in component INa (dimensionless): 0.573816
 - j in component INa (dimensionless): 0.572992
 - hsp in component INa (dimensionless): 0.326800
 - jp in component INa (dimensionless): 0.572313
 - mL in component INaL (dimensionless): 0.000352
 - hL in component INaL (dimensionless): 0.347693
 - hLp in component INaL (dimensionless): 0.151934
 - a in component Ito (dimensionless): 0.001249
 - iF in component Ito (dimensionless): 0.999207
 - iS in component Ito (dimensionless): 0.366878
 - ap in component Ito (dimensionless): 0.000637
 - iFp in component Ito (dimensionless): 0.999207
 - iSp in component Ito (dimensionless): 0.401536
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.843566
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.995795
 - jca in component ICaL (dimensionless): 0.998134
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005860
 - xrf in component IKr (dimensionless): 0.000391
 - xrs in component IKr (dimensionless): 0.672362
 - xs1 in component IKs (dimensionless): 0.385022
 - xs2 in component IKs (dimensionless): 0.000280
 - xk1 in component IK1 (dimensionless): 0.996779
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
08:36:42 (5205): called boinc_finish(0)

</stderr_txt>
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