𝕏

Task 55712550

Name HuVeMOp_20240702153647868011_ORdGradInc_k_26-CLVPET_Block_Kr_70-conf_2_1
Workunit 26454521
Created 2 Jul 2024, 13:36:54 UTC
Sent 2 Jul 2024, 14:29:59 UTC
Report deadline 5 Jul 2024, 17:22:47 UTC
Received 2 Jul 2024, 18:17:58 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 227516
Run time 1 hours 47 min 48 sec
CPU time 1 hours 47 min 48 sec
Validate state Valid
Credit 49.36
Device peak FLOPS 3.77 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.03 MB
Peak swap size 6.23 MB
Peak disk usage 0.06 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-CLVPET_Block_Kr_70-conf_2.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-CLVPET_Block_Kr_70-conf_2_1_r1924607210_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-CLVPET_Block_Kr_70-conf_2_1_r1924607210_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 105.224249
     * GNaL_b in INaL: 0.005816
     * Gto_b in Ito: 0.083357
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.009696
     * GKs_b in IKs: 0.001913
     * GK1_b in IK1: 0.161300
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 70.592112
     * GKb_b in IKb: 0.003775
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030098
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 7319291, states[0] = -94.829160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 14450215, states[0] = -94.876451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24857807, states[0] = -94.756271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35158275, states[0] = -18.722620, states[40]= 0.003925
Saving checkpoint... 
Iteration: 45257934, states[0] = -56.373963, states[40]= 0.000084
Saving checkpoint... 
Iteration: 55796777, states[0] = -91.341978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 66038148, states[0] = 26.567235, states[40]= 0.002940
Saving checkpoint... 
Iteration: 76225972, states[0] = -39.411774, states[40]= 0.001141
Saving checkpoint... 
Iteration: 86344036, states[0] = -94.660578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96616677, states[0] = 0.902158, states[40]= 0.004871
Saving checkpoint... 
Iteration: 106894320, states[0] = -94.715704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117124592, states[0] = -2.074622, states[40]= 0.004435
Saving checkpoint... 
Iteration: 127433422, states[0] = -94.742088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 137492065, states[0] = -94.768828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147750443, states[0] = -47.864651, states[40]= 0.000322
Saving checkpoint... 
Iteration: 157912606, states[0] = -94.724110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 168109618, states[0] = 3.868769, states[40]= 0.005086
Saving checkpoint... 
Iteration: 178339564, states[0] = -94.637333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 188632800, states[0] = -5.262343, states[40]= 0.003791
Saving checkpoint... 
Iteration: 198910933, states[0] = -94.720833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 209191962, states[0] = -26.714763, states[40]= 0.004438
Saving checkpoint... 
Iteration: 219691126, states[0] = -26.459067, states[40]= 0.004506
Saving checkpoint... 
Iteration: 229698607, states[0] = -28.684913, states[40]= 0.003841
Saving checkpoint... 
Iteration: 240006581, states[0] = 31.625434, states[40]= 0.135866
Saving checkpoint... 
Iteration: 250072433, states[0] = 16.719519, states[40]= 0.004810
Saving checkpoint... 
Iteration: 260348436, states[0] = -94.649647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270696976, states[0] = -28.173438, states[40]= 0.004003
Saving checkpoint... 
Iteration: 281146205, states[0] = -11.086906, states[40]= 0.002717
Saving checkpoint... 
Iteration: 291578844, states[0] = 14.646220, states[40]= 0.004990
Saving checkpoint... 
Iteration: 301863216, states[0] = -94.670216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 312096940, states[0] = 8.480541, states[40]= 0.005199
Saving checkpoint... 
Iteration: 322214331, states[0] = -33.679858, states[40]= 0.002296
Saving checkpoint... 
Iteration: 329417391, states[0] = -94.724475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339799792, states[0] = -83.472962, states[40]= 0.000001
Saving checkpoint... 
Iteration: 349899693, states[0] = -94.709857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 360059805, states[0] = 20.621314, states[40]= 0.004271
Saving checkpoint... 
Iteration: 370266244, states[0] = -54.790881, states[40]= 0.000101
Saving checkpoint... 
Iteration: 380334970, states[0] = -94.626683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 390224588, states[0] = -37.248309, states[40]= 0.001477
Saving checkpoint... 
Iteration: 400378540, states[0] = -94.688457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 407830190, states[0] = -94.615843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 418312147, states[0] = -93.924162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 428440319, states[0] = -94.739528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 438735530, states[0] = -41.350243, states[40]= 0.000848
Saving checkpoint... 
Iteration: 448936955, states[0] = -94.737446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459246302, states[0] = -45.712206, states[40]= 0.000447
Saving checkpoint... 
Iteration: 469747166, states[0] = -46.076492, states[40]= 0.000423
Saving checkpoint... 
Iteration: 480136251, states[0] = -6.695039, states[40]= 0.003480
Saving checkpoint... 
Iteration: 490386349, states[0] = -94.696631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 500595642, states[0] = 8.937520, states[40]= 0.005198
Saving checkpoint... 
Iteration: 510809079, states[0] = -93.022881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521053087, states[0] = 22.610898, states[40]= 0.003906
Saving checkpoint... 
Iteration: 531350036, states[0] = -94.651149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 541619697, states[0] = 0.130439, states[40]= 0.004744
Saving checkpoint... 
Iteration: 551703018, states[0] = -30.013081, states[40]= 0.003407
Saving checkpoint... 
Iteration: 561991722, states[0] = -94.763035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 572359883, states[0] = -94.665047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582668999, states[0] = -19.851465, states[40]= 0.004660
Saving checkpoint... 
Iteration: 592824684, states[0] = -94.592023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602964694, states[0] = -94.751944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 613170693, states[0] = -20.385394, states[40]= 0.004827
Saving checkpoint... 
Iteration: 623578120, states[0] = 14.886410, states[40]= 0.004972
Saving checkpoint... 
Iteration: 633982669, states[0] = -94.759510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644583124, states[0] = 13.227340, states[40]= 0.005077
Saving checkpoint... 
Iteration: 654703701, states[0] = -30.226425, states[40]= 0.003338
Saving checkpoint... 
Iteration: 664965728, states[0] = -94.752276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 675198668, states[0] = -28.674070, states[40]= 0.003843
Saving checkpoint... 
Iteration: 685349341, states[0] = -94.649744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 695579074, states[0] = 14.572956, states[40]= 0.004995
Saving checkpoint... 
Iteration: 705893104, states[0] = -94.702856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 716204780, states[0] = -30.565518, states[40]= 0.003228
Saving checkpoint... 
Iteration: 726461554, states[0] = -94.750172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 736783617, states[0] = -65.214943, states[40]= 0.000017
Saving checkpoint... 
Iteration: 747057493, states[0] = 21.311261, states[40]= 0.004149
Saving checkpoint... 
Iteration: 757413021, states[0] = -94.720068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 764056344, states[0] = 21.651804, states[40]= 0.004087
Saving checkpoint... 
Iteration: 774374955, states[0] = -94.683481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 781481810, states[0] = -94.758829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791776056, states[0] = -60.133260, states[40]= 0.000040
Saving checkpoint... 
Iteration: 802175918, states[0] = -21.976869, states[40]= 0.005087
Saving checkpoint... 
Iteration: 812875027, states[0] = -94.683473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 823170545, states[0] = -20.338920, states[40]= 0.004814
Saving checkpoint... 
Iteration: 833514493, states[0] = 31.122676, states[40]= 0.012501
Saving checkpoint... 
Iteration: 843703553, states[0] = -30.179837, states[40]= 0.003353
Saving checkpoint... 
Iteration: 853972756, states[0] = -94.754951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 864200083, states[0] = -29.105513, states[40]= 0.003703
Saving checkpoint... 
Iteration: 874489653, states[0] = -94.761560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 884912248, states[0] = -94.719159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 895125417, states[0] = -2.135123, states[40]= 0.004404
Saving checkpoint... 
Iteration: 905373085, states[0] = -94.680980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 915507587, states[0] = 31.134540, states[40]= 0.098995
Saving checkpoint... 
Iteration: 926006622, states[0] = 31.601118, states[40]= 0.134093
Saving checkpoint... 
Iteration: 936267495, states[0] = -55.419607, states[40]= 0.000091
Saving checkpoint... 
Iteration: 946667467, states[0] = -19.357897, states[40]= 0.004474
Saving checkpoint... 
Iteration: 956777343, states[0] = -60.919029, states[40]= 0.000035
Saving checkpoint... 
Iteration: 967027101, states[0] = 29.725115, states[40]= 0.002966
Saving checkpoint... 
Iteration: 977097656, states[0] = 8.230864, states[40]= 0.005199
Saving checkpoint... 
Iteration: 987271222, states[0] = -57.378142, states[40]= 0.000065
Saving checkpoint... 
Iteration: 997413421, states[0] = -94.719816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1007675906, states[0] = -21.973050, states[40]= 0.005087
Saving checkpoint... 
Iteration: 1018042860, states[0] = 25.583227, states[40]= 0.003356
Saving checkpoint... 
Iteration: 1028254606, states[0] = -49.306829, states[40]= 0.000254
Saving checkpoint... 
Iteration: 1038460458, states[0] = -94.748911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1048643523, states[0] = -9.896237, states[40]= 0.002870
Saving checkpoint... 
Iteration: 1058857339, states[0] = -94.660412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1069390239, states[0] = -94.699200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1079640955, states[0] = -8.760529, states[40]= 0.003063
Saving checkpoint... 
Iteration: 1089832482, states[0] = -94.619842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1100158088, states[0] = -16.040909, states[40]= 0.003097
Saving checkpoint... 
Iteration: 1110442093, states[0] = -94.738964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1120663524, states[0] = -18.032433, states[40]= 0.003890
Saving checkpoint... 
Iteration: 1130940597, states[0] = -94.738036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141337921, states[0] = -94.630294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1151948506, states[0] = -94.742488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1162148766, states[0] = -12.196451, states[40]= 0.002636
Saving checkpoint... 
Iteration: 1172454805, states[0] = -94.745776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182684920, states[0] = -24.615638, states[40]= 0.004909
Saving checkpoint... 
Iteration: 1193027073, states[0] = 29.731257, states[40]= 0.002967
Saving checkpoint... 
Iteration: 1203459618, states[0] = -94.748114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1213794306, states[0] = -75.684892, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1223994543, states[0] = -94.762464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234311308, states[0] = -93.740412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244480526, states[0] = -94.757236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254792525, states[0] = -73.527231, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1265158650, states[0] = -16.256118, states[40]= 0.003166
Saving checkpoint... 
Iteration: 1275316135, states[0] = -94.382144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285629127, states[0] = -3.656681, states[40]= 0.004121
Saving checkpoint... 
Iteration: 1295908482, states[0] = -94.715156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306182201, states[0] = -23.824913, states[40]= 0.005021
Saving checkpoint... 
Iteration: 1316656854, states[0] = -15.560051, states[40]= 0.002959
Saving checkpoint... 
Iteration: 1327283747, states[0] = -65.310519, states[40]= 0.000016
Saving checkpoint... 
Iteration: 1337466472, states[0] = -94.751037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1347850521, states[0] = -94.649941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1358059153, states[0] = 20.817344, states[40]= 0.004237
Saving checkpoint... 
Iteration: 1368180059, states[0] = -23.199442, states[40]= 0.005078
Saving checkpoint... 
Iteration: 1378410271, states[0] = -94.716418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1388707066, states[0] = -31.291094, states[40]= 0.002997
Saving checkpoint... 
Iteration: 1399054977, states[0] = 22.055845, states[40]= 0.004012
Saving checkpoint... 
Iteration: 1409461109, states[0] = -94.748353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1419922412, states[0] = -94.725530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1430021633, states[0] = 30.699553, states[40]= 0.003651
Saving checkpoint... 
Iteration: 1440199436, states[0] = -28.906962, states[40]= 0.003767
Saving checkpoint... 
Iteration: 1450307172, states[0] = -91.998741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1460820239, states[0] = -94.535946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470839850, states[0] = -94.632838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481160468, states[0] = -16.937629, states[40]= 0.003416
Saving checkpoint... 
Iteration: 1491510967, states[0] = 30.930276, states[40]= 0.034355
Saving checkpoint... 
Iteration: 1502037717, states[0] = -11.167675, states[40]= 0.002597
Saving checkpoint... 
Iteration: 1512308020, states[0] = 16.291029, states[40]= 0.006473
Saving checkpoint... 
Iteration: 1519353431, states[0] = -22.580459, states[40]= 0.006693
Saving checkpoint... 
Iteration: 1529543773, states[0] = -68.387590, states[40]= 0.000015
Saving checkpoint... 
Iteration: 1539791857, states[0] = -94.609984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1550238690, states[0] = -94.593755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1560585403, states[0] = -94.542730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1570988119, states[0] = -94.566344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1581040164, states[0] = -94.491957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1591371401, states[0] = -94.483867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1601690080, states[0] = -94.468038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1611971116, states[0] = -94.359338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1621916555, states[0] = -94.403544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1631787197, states[0] = -94.402904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1642072116, states[0] = -94.398131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1652325503, states[0] = -94.394766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1662800839, states[0] = -27.729557, states[40]= 0.005034
Saving checkpoint... 
Iteration: 1673100186, states[0] = -94.354393, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -94.267482
 - CaMKt in component CaMK (millimolar): 0.001256
 - cass in component intracellular_ions (millimolar): 0.000083
 - nai in component intracellular_ions (millimolar): 6.149283
 - nass in component intracellular_ions (millimolar): 6.149357
 - ki in component intracellular_ions (millimolar): 145.777951
 - kss in component intracellular_ions (millimolar): 145.777944
 - cansr in component intracellular_ions (millimolar): 1.482000
 - cajsr in component intracellular_ions (millimolar): 1.481481
 - cai in component intracellular_ions (millimolar): 0.000085
 - m in component INa (dimensionless): 0.003858
 - hf in component INa (dimensionless): 0.868549
 - hs in component INa (dimensionless): 0.868549
 - j in component INa (dimensionless): 0.868551
 - hsp in component INa (dimensionless): 0.704634
 - jp in component INa (dimensionless): 0.868551
 - mL in component INaL (dimensionless): 0.000056
 - hL in component INaL (dimensionless): 0.712130
 - hLp in component INaL (dimensionless): 0.519044
 - a in component Ito (dimensionless): 0.000651
 - iF in component Ito (dimensionless): 0.999854
 - iS in component Ito (dimensionless): 0.995922
 - ap in component Ito (dimensionless): 0.000331
 - iFp in component Ito (dimensionless): 0.999854
 - iSp in component Ito (dimensionless): 0.998525
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.997557
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002460
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.003537
 - xs1 in component IKs (dimensionless): 0.036515
 - xs2 in component IKs (dimensionless): 0.000094
 - xk1 in component IK1 (dimensionless): 0.997499
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
13:35:49 (8056): called boinc_finish(0)

</stderr_txt>
]]>


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