𝕏

Task 55712517

Name HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_ENDO_5000-conf_1_0
Workunit 26454505
Created 2 Jul 2024, 13:36:54 UTC
Sent 2 Jul 2024, 14:32:25 UTC
Report deadline 5 Jul 2024, 14:32:25 UTC
Received 3 Jul 2024, 13:59:21 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 238615
Run time 2 hours 27 min 32 sec
CPU time 2 hours 26 min 26 sec
Validate state Initial
Credit 0.00
Device peak FLOPS 3.23 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.39 MB
Peak swap size 3.69 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.14.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_ENDO_5000-conf_1.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_ENDO_5000-conf_1_0_r1799805094_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240702153647868011_ORdGradInc_k_26-Drouin_ENDO_5000-conf_1_0_r1799805094_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.228411
     * GNaL_b in INaL: 0.005739
     * Gto_b in Ito: 0.087470
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031887
     * GKs_b in IKs: 0.001897
     * GK1_b in IK1: 0.164995
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 69.727719
     * GKb_b in IKb: 0.003787
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033402
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 7045540, states[0] = -94.120861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 13860337, states[0] = -94.056932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 20700876, states[0] = -94.026107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 27554885, states[0] = 22.939228, states[40]= 0.000642
Saving checkpoint... 
Iteration: 34476895, states[0] = -93.958276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 41330163, states[0] = -93.962679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48203922, states[0] = -93.973294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 55017897, states[0] = 31.535625, states[40]= 0.003857
Saving checkpoint... 
Iteration: 61811685, states[0] = -93.941156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68660929, states[0] = -93.957298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 75499366, states[0] = -93.928093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 82373409, states[0] = -93.931371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 89139282, states[0] = -93.942096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95996533, states[0] = -93.961959, states[40]= 0.000000
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Iteration: 102837041, states[0] = -93.749049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109701499, states[0] = -93.932544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116376105, states[0] = -93.948367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 123290093, states[0] = -93.967179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130102561, states[0] = 3.416433, states[40]= 0.003423
Saving checkpoint... 
Iteration: 138334588, states[0] = -93.966509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145209867, states[0] = -84.028188, states[40]= 0.000001
Saving checkpoint... 
Iteration: 152048573, states[0] = -93.934214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 158904808, states[0] = -93.947283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 165803948, states[0] = -93.966855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 172490871, states[0] = -93.929211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 179338789, states[0] = -93.937392, states[40]= 0.000000
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Iteration: 186200022, states[0] = -93.953774, states[40]= 0.000000
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Iteration: 192890108, states[0] = -93.838675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 199755079, states[0] = -93.931485, states[40]= 0.000000
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Iteration: 206595143, states[0] = -93.942226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213514744, states[0] = -93.960592, states[40]= 0.000000
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Iteration: 220222658, states[0] = -92.763241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 227094304, states[0] = -93.933379, states[40]= 0.000000
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Iteration: 234259365, states[0] = -93.938708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 242760388, states[0] = -93.498905, states[40]= 0.000000
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Iteration: 249569642, states[0] = -93.933661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 256487971, states[0] = -93.944751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 263432447, states[0] = -93.963451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271827966, states[0] = -93.937368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 277988665, states[0] = -93.921251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284178202, states[0] = -93.940230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290316566, states[0] = -93.698640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296525720, states[0] = -93.943703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 302661020, states[0] = -39.144453, states[40]= 0.001015
Saving checkpoint... 
Iteration: 308938793, states[0] = -93.945968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 315137622, states[0] = -21.740667, states[40]= 0.002033
Saving checkpoint... 
Iteration: 321356089, states[0] = -93.948342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 330235870, states[0] = -93.367157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339515943, states[0] = -93.934231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 348802271, states[0] = -93.949970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358118497, states[0] = -93.958314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367211385, states[0] = -93.931637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 376392603, states[0] = -93.947147, states[40]= 0.000000
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Iteration: 385231915, states[0] = -93.317906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 394477513, states[0] = -93.934687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 403531887, states[0] = -93.959561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 412862392, states[0] = -93.796981, states[40]= 0.000000
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Iteration: 421990569, states[0] = -93.934439, states[40]= 0.000000
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Iteration: 431061170, states[0] = -93.958398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 440361407, states[0] = -93.795245, states[40]= 0.000000
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Iteration: 449028402, states[0] = -93.943337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458029116, states[0] = -93.937908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466654399, states[0] = -93.940377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 475774202, states[0] = -93.966360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482531519, states[0] = 29.959451, states[40]= 0.000147
Saving checkpoint... 
Iteration: 489394792, states[0] = -93.935800, states[40]= 0.000000
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Iteration: 496137573, states[0] = -93.955400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502751868, states[0] = -93.458966, states[40]= 0.000000
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Iteration: 509519304, states[0] = -93.933849, states[40]= 0.000000
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Iteration: 516153866, states[0] = -93.954762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 522929917, states[0] = -93.880884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 529708351, states[0] = -93.931354, states[40]= 0.000000
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Iteration: 535751823, states[0] = -93.966129, states[40]= 0.000000
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Iteration: 541913696, states[0] = -93.935390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 548106348, states[0] = -93.956184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554290937, states[0] = -93.937481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 561625495, states[0] = -93.940825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 570735856, states[0] = -93.965828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579131037, states[0] = -93.940668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 585883343, states[0] = -93.964351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592644746, states[0] = -27.032563, states[40]= 0.002494
Saving checkpoint... 
Iteration: 599430082, states[0] = -93.935016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 606289169, states[0] = -93.949891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 614188814, states[0] = -93.939361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 623478538, states[0] = -93.961120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 632847692, states[0] = -93.769673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 642144543, states[0] = -93.931909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 651405695, states[0] = -93.946231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660709868, states[0] = -93.964949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 670035376, states[0] = 29.073382, states[40]= 0.000150
Saving checkpoint... 
Iteration: 676770271, states[0] = -93.937627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683324097, states[0] = -93.965518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 691416641, states[0] = -93.945840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 700671546, states[0] = -93.962909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709721873, states[0] = -93.930844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 717395674, states[0] = -93.928983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726038473, states[0] = -93.958682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 733356176, states[0] = -93.964771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741037855, states[0] = -93.958676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 750397199, states[0] = -93.846438, states[40]= 0.000000
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Iteration: 759726404, states[0] = -93.930694, states[40]= 0.000000
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Iteration: 766641431, states[0] = -93.940072, states[40]= 0.000000
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Iteration: 773466910, states[0] = -93.961249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780282377, states[0] = -93.588552, states[40]= 0.000000
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Iteration: 787166216, states[0] = -93.931356, states[40]= 0.000000
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Iteration: 793820740, states[0] = -93.948512, states[40]= 0.000000
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Iteration: 800580788, states[0] = -93.951125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 807233156, states[0] = -93.930523, states[40]= 0.000000
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Iteration: 813990275, states[0] = -93.943596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 820694944, states[0] = -93.964020, states[40]= 0.000000
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Iteration: 827372493, states[0] = -93.928996, states[40]= 0.000000
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Iteration: 834212052, states[0] = -93.938455, states[40]= 0.000000
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Iteration: 841021686, states[0] = -93.959092, states[40]= 0.000000
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Iteration: 847957513, states[0] = -93.901746, states[40]= 0.000000
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Iteration: 854835743, states[0] = -93.929314, states[40]= 0.000000
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Iteration: 861491870, states[0] = -93.943461, states[40]= 0.000000
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Iteration: 868372738, states[0] = -93.964090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 875353778, states[0] = -93.780797, states[40]= 0.000000
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Iteration: 882165221, states[0] = -93.931182, states[40]= 0.000000
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Iteration: 888832756, states[0] = -93.947950, states[40]= 0.000000
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Iteration: 895513715, states[0] = -93.931343, states[40]= 0.000000
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Iteration: 902291155, states[0] = -93.929692, states[40]= 0.000000
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Iteration: 910277698, states[0] = -93.570380, states[40]= 0.000000
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Iteration: 919602543, states[0] = -93.931905, states[40]= 0.000000
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Iteration: 927931125, states[0] = -93.881154, states[40]= 0.000000
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Iteration: 934787190, states[0] = -93.929671, states[40]= 0.000000
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Iteration: 941548275, states[0] = -93.941883, states[40]= 0.000000
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Iteration: 948392801, states[0] = -93.963370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 955030442, states[0] = 30.181801, states[40]= 0.000156
Saving checkpoint... 
Iteration: 961817336, states[0] = -93.936204, states[40]= 0.000000
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Iteration: 968633126, states[0] = -93.954642, states[40]= 0.000000
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Iteration: 975421117, states[0] = -93.871870, states[40]= 0.000000
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Iteration: 982648955, states[0] = -30.126948, states[40]= 0.002291
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Iteration: 989309137, states[0] = -93.936297, states[40]= 0.000000
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Iteration: 996034176, states[0] = -93.958318, states[40]= 0.000000
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Iteration: 1002853019, states[0] = -93.779136, states[40]= 0.000000
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Iteration: 1009736362, states[0] = -93.930090, states[40]= 0.000000
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Iteration: 1016624236, states[0] = -93.939963, states[40]= 0.000000
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Iteration: 1023367169, states[0] = -93.963934, states[40]= 0.000000
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Iteration: 1030206310, states[0] = -79.232233, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1036936736, states[0] = -93.934055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1043753899, states[0] = -93.950205, states[40]= 0.000000
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Iteration: 1050654043, states[0] = -93.960869, states[40]= 0.000000
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Iteration: 1057488471, states[0] = -93.927454, states[40]= 0.000000
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Iteration: 1064333263, states[0] = -93.935720, states[40]= 0.000000
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Iteration: 1071150349, states[0] = -93.953806, states[40]= 0.000000
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Iteration: 1077770975, states[0] = -93.542972, states[40]= 0.000000
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Iteration: 1084508927, states[0] = -93.932873, states[40]= 0.000000
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Iteration: 1091397723, states[0] = -93.945601, states[40]= 0.000000
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Iteration: 1097989310, states[0] = -93.919971, states[40]= 0.000000
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Iteration: 1104835007, states[0] = -93.928832, states[40]= 0.000000
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Iteration: 1111552183, states[0] = -93.941455, states[40]= 0.000000
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Iteration: 1118255122, states[0] = -93.965025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1125108256, states[0] = 0.251828, states[40]= 0.003663
Saving checkpoint... 
Iteration: 1131951939, states[0] = -93.933633, states[40]= 0.000000
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Iteration: 1138678534, states[0] = -93.952650, states[40]= 0.000000
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Iteration: 1145604860, states[0] = -93.954786, states[40]= 0.000000
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Iteration: 1152521802, states[0] = 31.430385, states[40]= 0.001051
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Iteration: 1159420175, states[0] = -93.934077, states[40]= 0.000000
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Iteration: 1166078590, states[0] = -93.956302, states[40]= 0.000000
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Iteration: 1172786423, states[0] = -93.602646, states[40]= 0.000000
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Iteration: 1179574852, states[0] = -93.931765, states[40]= 0.000000
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Iteration: 1186215380, states[0] = -93.951250, states[40]= 0.000000
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Iteration: 1193076690, states[0] = -93.949505, states[40]= 0.000000
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Iteration: 1199964026, states[0] = -93.927395, states[40]= 0.000000
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Iteration: 1206664069, states[0] = -93.938722, states[40]= 0.000000
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Iteration: 1213835390, states[0] = -93.947232, states[40]= 0.000000
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Iteration: 1220565232, states[0] = -93.946859, states[40]= 0.000000
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Iteration: 1227272032, states[0] = -93.929264, states[40]= 0.000000
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Iteration: 1234041159, states[0] = -93.941485, states[40]= 0.000000
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Iteration: 1240851697, states[0] = -93.963885, states[40]= 0.000000
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Iteration: 1247636339, states[0] = -20.758152, states[40]= 0.001913
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Iteration: 1254425483, states[0] = -93.933807, states[40]= 0.000000
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Iteration: 1261101313, states[0] = -93.955259, states[40]= 0.000000
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Iteration: 1267736151, states[0] = -93.367730, states[40]= 0.000000
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Iteration: 1274516898, states[0] = -93.932386, states[40]= 0.000000
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Iteration: 1281341823, states[0] = -93.946901, states[40]= 0.000000
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Iteration: 1288151353, states[0] = -93.960167, states[40]= 0.000000
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Iteration: 1294861741, states[0] = -93.928188, states[40]= 0.000000
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Iteration: 1301634531, states[0] = -93.939177, states[40]= 0.000000
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Iteration: 1308457312, states[0] = -93.960547, states[40]= 0.000000
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Iteration: 1315277415, states[0] = -93.568462, states[40]= 0.000000
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Iteration: 1322110614, states[0] = -93.931011, states[40]= 0.000000
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Iteration: 1328824993, states[0] = -93.947332, states[40]= 0.000000
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Iteration: 1335492824, states[0] = -93.921249, states[40]= 0.000000
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Iteration: 1342228159, states[0] = -93.929533, states[40]= 0.000000
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Iteration: 1348516382, states[0] = -93.958301, states[40]= 0.000000
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Iteration: 1354562545, states[0] = -93.931589, states[40]= 0.000000
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Iteration: 1360767012, states[0] = -93.964622, states[40]= 0.000000
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Iteration: 1366930451, states[0] = -93.933508, states[40]= 0.000000
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Iteration: 1373177330, states[0] = -93.961976, states[40]= 0.000000
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Iteration: 1379339547, states[0] = -93.934994, states[40]= 0.000000
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Iteration: 1385472125, states[0] = -93.909996, states[40]= 0.000000
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Iteration: 1391505756, states[0] = -93.942066, states[40]= 0.000000
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Iteration: 1397726174, states[0] = -93.116389, states[40]= 0.000000
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Iteration: 1403953247, states[0] = -93.943429, states[40]= 0.000000
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Iteration: 1410178468, states[0] = -52.769011, states[40]= 0.000160
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Iteration: 1416468997, states[0] = -93.942980, states[40]= 0.000000
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Iteration: 1422551842, states[0] = 24.193911, states[40]= 0.000367
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Iteration: 1428868934, states[0] = -93.945789, states[40]= 0.000000
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Iteration: 1436171603, states[0] = -93.952319, states[40]= 0.000000
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Iteration: 1442243486, states[0] = -93.929162, states[40]= 0.000000
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Iteration: 1448460471, states[0] = -93.960161, states[40]= 0.000000
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Iteration: 1454704378, states[0] = -93.929590, states[40]= 0.000000
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Iteration: 1460910327, states[0] = -93.961833, states[40]= 0.000000
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Iteration: 1467165128, states[0] = -93.930038, states[40]= 0.000000
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Iteration: 1475223591, states[0] = -92.885962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483061589, states[0] = -93.945456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489875819, states[0] = -93.927665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1496737260, states[0] = -93.936658, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.802461
 - CaMKt in component CaMK (millimolar): 0.001591
 - cass in component intracellular_ions (millimolar): 0.000102
 - nai in component intracellular_ions (millimolar): 6.729894
 - nass in component intracellular_ions (millimolar): 6.730018
 - ki in component intracellular_ions (millimolar): 145.130772
 - kss in component intracellular_ions (millimolar): 145.130762
 - cansr in component intracellular_ions (millimolar): 1.838329
 - cajsr in component intracellular_ions (millimolar): 1.838205
 - cai in component intracellular_ions (millimolar): 0.000106
 - m in component INa (dimensionless): 0.004043
 - hf in component INa (dimensionless): 0.859577
 - hs in component INa (dimensionless): 0.859577
 - j in component INa (dimensionless): 0.859579
 - hsp in component INa (dimensionless): 0.688487
 - jp in component INa (dimensionless): 0.859581
 - mL in component INaL (dimensionless): 0.000061
 - hL in component INaL (dimensionless): 0.699239
 - hLp in component INaL (dimensionless): 0.503884
 - a in component Ito (dimensionless): 0.000671
 - iF in component Ito (dimensionless): 0.999842
 - iS in component Ito (dimensionless): 0.997562
 - ap in component Ito (dimensionless): 0.000342
 - iFp in component Ito (dimensionless): 0.999842
 - iSp in component Ito (dimensionless): 0.999156
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998698
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005462
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.002176
 - xs1 in component IKs (dimensionless): 0.024485
 - xs2 in component IKs (dimensionless): 0.000099
 - xk1 in component IK1 (dimensionless): 0.997611
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
15:50:09 (4163): called boinc_finish(0)

</stderr_txt>
]]>


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