𝕏

Task 55712245

Name HuVeMOp_20240629110615760215_ORdGradInc_k_25-Drouin_MID_6000-conf_433_2
Workunit 26247330
Created 2 Jul 2024, 12:50:13 UTC
Sent 2 Jul 2024, 14:36:38 UTC
Report deadline 5 Jul 2024, 14:36:38 UTC
Received 3 Jul 2024, 20:14:09 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 227034
Run time 1 hours 47 min 2 sec
CPU time 1 hours 43 min 55 sec
Validate state Valid
Credit 46.09
Device peak FLOPS 2.61 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.96 MB
Peak swap size 6.22 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.22.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Drouin_MID_6000-conf_433.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Drouin_MID_6000-conf_433_2_r1885681174_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Drouin_MID_6000-conf_433_2_r1885681174_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 100.856660
     * GNaL_b in INaL: 0.006000
     * Gto_b in Ito: 0.091822
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031790
     * GKs_b in IKs: 0.001840
     * GK1_b in IK1: 0.157095
     * Gncx_b in INaCa_i: 0.000974
     * Pnak_b in INaK: 69.292051
     * GKb_b in IKb: 0.003721
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.046692
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 9099557, states[0] = 19.905668, states[40]= 0.000007
Saving checkpoint... 
Iteration: 18339738, states[0] = -49.613835, states[40]= 0.000529
Saving checkpoint... 
Iteration: 27647473, states[0] = -94.194003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 36763340, states[0] = -94.215832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 46002900, states[0] = -94.222513, states[40]= 0.000001
Saving checkpoint... 
Iteration: 55126611, states[0] = -94.224730, states[40]= 0.000001
Saving checkpoint... 
Iteration: 64227842, states[0] = -94.226945, states[40]= 0.000001
Saving checkpoint... 
Iteration: 73299337, states[0] = -94.229488, states[40]= 0.000001
Saving checkpoint... 
Iteration: 82352536, states[0] = -94.231942, states[40]= 0.000001
Saving checkpoint... 
Iteration: 91477792, states[0] = -94.232040, states[40]= 0.000001
Saving checkpoint... 
Iteration: 100682353, states[0] = -94.230481, states[40]= 0.000001
Saving checkpoint... 
Iteration: 110045448, states[0] = -94.227509, states[40]= 0.000001
Saving checkpoint... 
Iteration: 119152875, states[0] = -94.228214, states[40]= 0.000001
Saving checkpoint... 
Iteration: 128337742, states[0] = -94.228174, states[40]= 0.000001
Saving checkpoint... 
Iteration: 137393952, states[0] = -94.228951, states[40]= 0.000001
Saving checkpoint... 
Iteration: 146498543, states[0] = -94.229271, states[40]= 0.000001
Saving checkpoint... 
Iteration: 155654001, states[0] = -94.229308, states[40]= 0.000001
Saving checkpoint... 
Iteration: 164739676, states[0] = -94.229581, states[40]= 0.000001
Saving checkpoint... 
Iteration: 173809565, states[0] = -94.229824, states[40]= 0.000001
Saving checkpoint... 
Iteration: 182996775, states[0] = -94.229793, states[40]= 0.000001
Saving checkpoint... 
Iteration: 192181091, states[0] = -17.044369, states[40]= 0.001205
Saving checkpoint... 
Iteration: 201603357, states[0] = -94.235562, states[40]= 0.000001
Saving checkpoint... 
Iteration: 210849925, states[0] = -94.260808, states[40]= 0.000001
Saving checkpoint... 
Iteration: 220071169, states[0] = -94.256542, states[40]= 0.000001
Saving checkpoint... 
Iteration: 229288860, states[0] = -94.250007, states[40]= 0.000001
Saving checkpoint... 
Iteration: 238417641, states[0] = -94.246565, states[40]= 0.000001
Saving checkpoint... 
Iteration: 247604918, states[0] = -94.242347, states[40]= 0.000001
Saving checkpoint... 
Iteration: 256572006, states[0] = -94.243023, states[40]= 0.000001
Saving checkpoint... 
Iteration: 265752382, states[0] = -94.239646, states[40]= 0.000001
Saving checkpoint... 
Iteration: 274878334, states[0] = -94.237716, states[40]= 0.000001
Saving checkpoint... 
Iteration: 284004132, states[0] = -94.236091, states[40]= 0.000001
Saving checkpoint... 
Iteration: 293070875, states[0] = -94.235321, states[40]= 0.000001
Saving checkpoint... 
Iteration: 302215659, states[0] = -94.233921, states[40]= 0.000001
Saving checkpoint... 
Iteration: 311559405, states[0] = -94.231700, states[40]= 0.000001
Saving checkpoint... 
Iteration: 320786035, states[0] = -94.230834, states[40]= 0.000001
Saving checkpoint... 
Iteration: 329960418, states[0] = -94.230402, states[40]= 0.000001
Saving checkpoint... 
Iteration: 339226208, states[0] = -33.964809, states[40]= 0.003683
Saving checkpoint... 
Iteration: 348341681, states[0] = -93.879929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357481842, states[0] = -94.167571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366515366, states[0] = -94.194544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 375726039, states[0] = -94.256209, states[40]= 0.000001
Saving checkpoint... 
Iteration: 385085512, states[0] = -94.255579, states[40]= 0.000001
Saving checkpoint... 
Iteration: 394601240, states[0] = -94.241716, states[40]= 0.000001
Saving checkpoint... 
Iteration: 403859805, states[0] = -94.237241, states[40]= 0.000001
Saving checkpoint... 
Iteration: 412957630, states[0] = -94.235881, states[40]= 0.000001
Saving checkpoint... 
Iteration: 422084734, states[0] = -94.234386, states[40]= 0.000001
Saving checkpoint... 
Iteration: 431352057, states[0] = -94.232089, states[40]= 0.000001
Saving checkpoint... 
Iteration: 440577208, states[0] = -94.230794, states[40]= 0.000001
Saving checkpoint... 
Iteration: 449686583, states[0] = -94.230303, states[40]= 0.000001
Saving checkpoint... 
Iteration: 458889093, states[0] = -94.229684, states[40]= 0.000001
Saving checkpoint... 
Iteration: 467978842, states[0] = -94.229460, states[40]= 0.000001
Saving checkpoint... 
Iteration: 477018330, states[0] = 32.020873, states[40]= -0.000000
Saving checkpoint... 
Iteration: 486183883, states[0] = -18.367987, states[40]= 0.001653
Saving checkpoint... 
Iteration: 495588234, states[0] = -94.229742, states[40]= 0.000001
Saving checkpoint... 
Iteration: 504756328, states[0] = -94.257317, states[40]= 0.000001
Saving checkpoint... 
Iteration: 513903431, states[0] = -94.259175, states[40]= 0.000001
Saving checkpoint... 
Iteration: 523009637, states[0] = -94.256847, states[40]= 0.000001
Saving checkpoint... 
Iteration: 532072392, states[0] = -94.254974, states[40]= 0.000001
Saving checkpoint... 
Iteration: 541206242, states[0] = -94.250799, states[40]= 0.000001
Saving checkpoint... 
Iteration: 550536028, states[0] = -94.242020, states[40]= 0.000001
Saving checkpoint... 
Iteration: 559751589, states[0] = -94.237833, states[40]= 0.000001
Saving checkpoint... 
Iteration: 568891884, states[0] = -94.235663, states[40]= 0.000001
Saving checkpoint... 
Iteration: 578006500, states[0] = -94.234164, states[40]= 0.000001
Saving checkpoint... 
Iteration: 587127018, states[0] = -94.232832, states[40]= 0.000001
Saving checkpoint... 
Iteration: 596302357, states[0] = -94.231299, states[40]= 0.000001
Saving checkpoint... 
Iteration: 605489687, states[0] = -94.230077, states[40]= 0.000001
Saving checkpoint... 
Iteration: 614532740, states[0] = -94.229799, states[40]= 0.000001
Saving checkpoint... 
Iteration: 623342624, states[0] = -94.230830, states[40]= 0.000001
Saving checkpoint... 
Iteration: 632729763, states[0] = -94.228898, states[40]= 0.000001
Saving checkpoint... 
Iteration: 641950272, states[0] = -94.228306, states[40]= 0.000001
Saving checkpoint... 
Iteration: 651067652, states[0] = 27.824538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660243316, states[0] = -45.384331, states[40]= 0.000952
Saving checkpoint... 
Iteration: 669394878, states[0] = -94.036053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678529548, states[0] = -94.201493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 687836923, states[0] = -94.258244, states[40]= 0.000001
Saving checkpoint... 
Iteration: 697040650, states[0] = -94.254777, states[40]= 0.000001
Saving checkpoint... 
Iteration: 706234320, states[0] = -94.248816, states[40]= 0.000001
Saving checkpoint... 
Iteration: 715344005, states[0] = -94.245608, states[40]= 0.000001
Saving checkpoint... 
Iteration: 724383769, states[0] = -94.244482, states[40]= 0.000001
Saving checkpoint... 
Iteration: 733626496, states[0] = -94.238885, states[40]= 0.000001
Saving checkpoint... 
Iteration: 742769891, states[0] = -94.236272, states[40]= 0.000001
Saving checkpoint... 
Iteration: 751829953, states[0] = -94.235281, states[40]= 0.000001
Saving checkpoint... 
Iteration: 760880916, states[0] = -94.234488, states[40]= 0.000001
Saving checkpoint... 
Iteration: 769917886, states[0] = -94.233929, states[40]= 0.000001
Saving checkpoint... 
Iteration: 778950872, states[0] = -94.233445, states[40]= 0.000001
Saving checkpoint... 
Iteration: 788150645, states[0] = -94.231222, states[40]= 0.000001
Saving checkpoint... 
Iteration: 797214979, states[0] = -94.230593, states[40]= 0.000001
Saving checkpoint... 
Iteration: 806256354, states[0] = -94.230196, states[40]= 0.000001
Saving checkpoint... 
Iteration: 815356192, states[0] = -94.229414, states[40]= 0.000001
Saving checkpoint... 
Iteration: 824751888, states[0] = -94.227504, states[40]= 0.000001
Saving checkpoint... 
Iteration: 833797565, states[0] = -94.227312, states[40]= 0.000001
Saving checkpoint... 
Iteration: 843094325, states[0] = 18.833906, states[40]= 0.000004
Saving checkpoint... 
Iteration: 852163068, states[0] = -7.513636, states[40]= 0.000542
Saving checkpoint... 
Iteration: 861176633, states[0] = -14.937193, states[40]= 0.000818
Saving checkpoint... 
Iteration: 870419683, states[0] = -94.083546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879673663, states[0] = -94.246970, states[40]= 0.000001
Saving checkpoint... 
Iteration: 888900830, states[0] = -94.256625, states[40]= 0.000001
Saving checkpoint... 
Iteration: 898087547, states[0] = -94.251993, states[40]= 0.000001
Saving checkpoint... 
Iteration: 907256524, states[0] = -94.246770, states[40]= 0.000001
Saving checkpoint... 
Iteration: 916616865, states[0] = -94.237812, states[40]= 0.000001
Saving checkpoint... 
Iteration: 925738234, states[0] = -94.235531, states[40]= 0.000001
Saving checkpoint... 
Iteration: 934848025, states[0] = -94.233753, states[40]= 0.000001
Saving checkpoint... 
Iteration: 944323493, states[0] = -94.228747, states[40]= 0.000001
Saving checkpoint... 
Iteration: 953639219, states[0] = -94.226999, states[40]= 0.000001
Saving checkpoint... 
Iteration: 962961642, states[0] = -94.226071, states[40]= 0.000001
Saving checkpoint... 
Iteration: 972109967, states[0] = 13.233058, states[40]= 0.000018
Saving checkpoint... 
Iteration: 981325400, states[0] = -93.807277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 990511008, states[0] = -94.187196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 999570053, states[0] = -94.219441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1008728825, states[0] = -94.252079, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1017931712, states[0] = -94.255259, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1027106229, states[0] = -94.250533, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1036304051, states[0] = -94.244507, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1045503644, states[0] = -94.239331, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1054618777, states[0] = -94.236822, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1063784526, states[0] = -94.233824, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1072950232, states[0] = -94.231425, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1082131321, states[0] = -94.229375, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1091263006, states[0] = -94.228178, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1100399252, states[0] = -94.227173, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1109575601, states[0] = -94.226185, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1118576011, states[0] = -94.226121, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1127639623, states[0] = -94.225796, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1136886316, states[0] = -94.225010, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1146040155, states[0] = 33.638772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1155510328, states[0] = -94.185566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1164519510, states[0] = -94.191823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1173581690, states[0] = -94.222742, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1182537732, states[0] = -94.202726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1191754963, states[0] = -94.252514, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1200706574, states[0] = -94.248788, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1209896535, states[0] = -94.254467, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1219003147, states[0] = -94.252229, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1228114796, states[0] = -94.248885, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1237205891, states[0] = -94.246015, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1246605783, states[0] = -94.235757, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1255915855, states[0] = -94.230603, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1265034354, states[0] = -94.229110, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1274161062, states[0] = -94.227773, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1283204056, states[0] = -94.227332, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1292256889, states[0] = -94.226838, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1301367257, states[0] = -94.225987, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1310655200, states[0] = -94.224474, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1319890812, states[0] = -94.223737, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1328828112, states[0] = -94.223817, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1338095085, states[0] = 18.564958, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1347266382, states[0] = -64.084846, states[40]= 0.000056
Saving checkpoint... 
Iteration: 1356439847, states[0] = -94.111820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1365557684, states[0] = -94.211548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374573157, states[0] = -94.218101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383384135, states[0] = -94.005677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392249541, states[0] = -50.132368, states[40]= 0.000488
Saving checkpoint... 
Iteration: 1401230735, states[0] = -36.641065, states[40]= 0.002798
Saving checkpoint... 
Iteration: 1410442968, states[0] = -94.115804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1419697775, states[0] = -94.246344, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1428952235, states[0] = -94.252020, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1438071141, states[0] = -94.248772, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1447170569, states[0] = -94.245651, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1456213164, states[0] = -94.244285, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1465210656, states[0] = -94.244299, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1474394447, states[0] = -94.239034, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1483544250, states[0] = -94.235407, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1492552238, states[0] = -94.235172, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.098283
 - CaMKt in component CaMK (millimolar): 0.001334
 - cass in component intracellular_ions (millimolar): 0.000094
 - nai in component intracellular_ions (millimolar): 7.695387
 - nass in component intracellular_ions (millimolar): 7.695535
 - ki in component intracellular_ions (millimolar): 144.144602
 - kss in component intracellular_ions (millimolar): 144.144589
 - cansr in component intracellular_ions (millimolar): 1.749559
 - cajsr in component intracellular_ions (millimolar): 1.750877
 - cai in component intracellular_ions (millimolar): 0.000099
 - m in component INa (dimensionless): 0.003924
 - hf in component INa (dimensionless): 0.865342
 - hs in component INa (dimensionless): 0.865342
 - j in component INa (dimensionless): 0.865342
 - hsp in component INa (dimensionless): 0.698814
 - jp in component INa (dimensionless): 0.865342
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.707460
 - hLp in component INaL (dimensionless): 0.513763
 - a in component Ito (dimensionless): 0.000658
 - iF in component Ito (dimensionless): 0.999850
 - iS in component Ito (dimensionless): 0.999134
 - ap in component Ito (dimensionless): 0.000335
 - iFp in component Ito (dimensionless): 0.999850
 - iSp in component Ito (dimensionless): 0.999680
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999261
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004077
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.000648
 - xs1 in component IKs (dimensionless): 0.019989
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997540
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
12:13:46 (1908): called boinc_finish(0)

</stderr_txt>
]]>


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