𝕏

Task 55711829

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-Pueyo_APDR-conf_173_2
Workunit 26440519
Created 2 Jul 2024, 12:14:51 UTC
Sent 2 Jul 2024, 14:24:10 UTC
Report deadline 6 Jul 2024, 0:00:10 UTC
Received 5 Jul 2024, 16:38:19 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 222504
Run time 1 hours 44 min 33 sec
CPU time 1 hours 21 min 52 sec
Validate state Valid
Credit 59.33
Device peak FLOPS 4.76 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 7.16 MB
Peak swap size 32.86 GB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Pueyo_APDR-conf_173.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Pueyo_APDR-conf_173_2_r1161895506_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Pueyo_APDR-conf_173_2_r1161895506_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 107.143801
     * GNaL_b in INaL: 0.005951
     * Gto_b in Ito: 0.084033
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031839
     * GKs_b in IKs: 0.001968
     * GK1_b in IK1: 0.163174
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 69.256187
     * GKb_b in IKb: 0.003833
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032450
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 24720607, states[0] = -94.902485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 49009678, states[0] = 23.232403, states[40]= 0.057292
Saving checkpoint... 
Iteration: 75068402, states[0] = 3.429893, states[40]= 0.004631
Saving checkpoint... 
Iteration: 101310468, states[0] = -94.957435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127462170, states[0] = -95.010528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 152224329, states[0] = -94.857911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 177304517, states[0] = -94.948900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201244504, states[0] = -94.887487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226596871, states[0] = -16.711938, states[40]= 0.001258


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Pueyo_APDR-conf_173.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Pueyo_APDR-conf_173_2_r1161895506_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Pueyo_APDR-conf_173_2_r1161895506_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 107.143801
     * GNaL_b in INaL: 0.005951
     * Gto_b in Ito: 0.084033
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031839
     * GKs_b in IKs: 0.001968
     * GK1_b in IK1: 0.163174
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 69.256187
     * GKb_b in IKb: 0.003833
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032450
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 226596871
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -16.711938 (After loading)
 - states[40]: 0.001258 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 243722593, states[0] = -94.853943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260440337, states[0] = -95.004310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 278100835, states[0] = -20.446001, states[40]= 0.000942
Saving checkpoint... 
Iteration: 296050335, states[0] = 11.435096, states[40]= 0.004995
Saving checkpoint... 
Iteration: 313527416, states[0] = 19.438842, states[40]= 0.006566
Saving checkpoint... 
Iteration: 327913829, states[0] = -94.998129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 344020083, states[0] = 21.234038, states[40]= 0.009719
Saving checkpoint... 
Iteration: 360683233, states[0] = -94.771836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 376401568, states[0] = -94.994720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 394507472, states[0] = 24.670669, states[40]= 0.095331
Saving checkpoint... 
Iteration: 414533383, states[0] = 17.619011, states[40]= 0.005732
Saving checkpoint... 
Iteration: 434667068, states[0] = -93.951353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 452868985, states[0] = -94.983574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 473196756, states[0] = -94.805104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493373189, states[0] = -94.985178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 513186415, states[0] = -94.781683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534082264, states[0] = -4.309840, states[40]= 0.003540
Saving checkpoint... 
Iteration: 555191606, states[0] = -94.794089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 575219680, states[0] = -94.848677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595522457, states[0] = 20.713365, states[40]= 0.008157
Saving checkpoint... 
Iteration: 615095893, states[0] = -15.787161, states[40]= 0.001366
Saving checkpoint... 
Iteration: 633149080, states[0] = -71.650510, states[40]= 0.000001
Saving checkpoint... 
Iteration: 650996822, states[0] = -95.012914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671197593, states[0] = -94.806705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690065877, states[0] = 4.877522, states[40]= 0.004725
Saving checkpoint... 
Iteration: 708396738, states[0] = -94.993070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727857074, states[0] = -94.978411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746479732, states[0] = -95.010643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 765525309, states[0] = 20.010035, states[40]= 0.007075
Saving checkpoint... 
Iteration: 786395654, states[0] = -94.992688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 806779797, states[0] = -94.927220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824648260, states[0] = -70.470119, states[40]= 0.000001
Saving checkpoint... 
Iteration: 843027020, states[0] = 19.549516, states[40]= 0.006649
Saving checkpoint... 
Iteration: 863217857, states[0] = -94.845310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 881996331, states[0] = -95.012709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 901558291, states[0] = 8.217124, states[40]= 0.004883
Saving checkpoint... 
Iteration: 919888741, states[0] = -94.990406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 938328619, states[0] = -94.963774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957653041, states[0] = -77.884532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 976001104, states[0] = 49.276267, states[40]= 0.033840
Saving checkpoint... 
Iteration: 992497276, states[0] = -95.012751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1006829275, states[0] = -94.964112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021935856, states[0] = -95.002854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1040281522, states[0] = -94.928695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1057354279, states[0] = -94.976946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073421866, states[0] = -94.999661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089607064, states[0] = -26.318648, states[40]= 0.000647
Saving checkpoint... 
Iteration: 1105543058, states[0] = 14.213500, states[40]= 0.005161
Saving checkpoint... 
Iteration: 1123153747, states[0] = -79.083539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141394747, states[0] = -94.992183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156299671, states[0] = -94.944094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1172400208, states[0] = -94.993816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1189072785, states[0] = 1.454825, states[40]= 0.004436
Saving checkpoint... 
Iteration: 1205994564, states[0] = -95.012290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1222505536, states[0] = 27.364248, states[40]= 0.138007
Saving checkpoint... 
Iteration: 1238314567, states[0] = -94.954795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1254221277, states[0] = -94.850990, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1271338398, states[0] = -94.969003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290482700, states[0] = -95.010708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1311655280, states[0] = -81.738532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1332052774, states[0] = 10.472064, states[40]= 0.004960
Saving checkpoint... 
Iteration: 1351782767, states[0] = -94.929652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1371030046, states[0] = 18.671037, states[40]= 0.006120
Saving checkpoint... 
Iteration: 1390066232, states[0] = 4.712338, states[40]= 0.004714
Saving checkpoint... 
Iteration: 1410133587, states[0] = -52.862733, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1428338803, states[0] = -94.969117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1449457721, states[0] = -95.006767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1469240527, states[0] = -94.880894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489292566, states[0] = -94.938161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1509926966, states[0] = 18.925361, states[40]= 0.007874
Saving checkpoint... 
Iteration: 1531259917, states[0] = 2.202834, states[40]= 0.005080
Saving checkpoint... 
Iteration: 1552120306, states[0] = -95.199039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1572984445, states[0] = -20.783272, states[40]= 0.000985
Saving checkpoint... 
Iteration: 1594116836, states[0] = -95.204418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1614913359, states[0] = 22.825351, states[40]= 0.027003
Saving checkpoint... 
Iteration: 1632524278, states[0] = -95.218195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1651285954, states[0] = -22.773680, states[40]= 0.000844
Saving checkpoint... 
Iteration: 1670776422, states[0] = -12.438543, states[40]= 0.002121
Saving checkpoint... 
Iteration: 1688334773, states[0] = -95.233267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1706175579, states[0] = -11.565547, states[40]= 0.002302
Saving checkpoint... 
Iteration: 1725221697, states[0] = -95.215374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1743396990, states[0] = -34.833324, states[40]= 0.000265
Saving checkpoint... 
Iteration: 1761852853, states[0] = -95.254295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1780840331, states[0] = 12.388204, states[40]= 0.006084
Saving checkpoint... 
Iteration: 1799670960, states[0] = -95.271463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1818981837, states[0] = -95.049834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1837387130, states[0] = -95.012750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1856658763, states[0] = -88.899922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1875858769, states[0] = -94.985937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1894373070, states[0] = -94.988569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1914323888, states[0] = -94.962720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1933045863, states[0] = 13.136736, states[40]= 0.005082
Saving checkpoint... 
Iteration: 1951331345, states[0] = -94.965469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1970375355, states[0] = -94.985471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1988937713, states[0] = -95.002848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2008667273, states[0] = -94.000722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2028062323, states[0] = 6.482697, states[40]= 0.004812
Saving checkpoint... 
Iteration: 2046338652, states[0] = -94.968640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2065070162, states[0] = 2.809960, states[40]= 0.004569
Saving checkpoint... 
Iteration: 2084293294, states[0] = -94.938348, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.888199
 - CaMKt in component CaMK (millimolar): 0.006983
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.622022
 - nass in component intracellular_ions (millimolar): 6.622082
 - ki in component intracellular_ions (millimolar): 145.355392
 - kss in component intracellular_ions (millimolar): 145.355373
 - cansr in component intracellular_ions (millimolar): 1.312933
 - cajsr in component intracellular_ions (millimolar): 1.274995
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003623
 - hf in component INa (dimensionless): 0.879764
 - hs in component INa (dimensionless): 0.879759
 - j in component INa (dimensionless): 0.879730
 - hsp in component INa (dimensionless): 0.725384
 - jp in component INa (dimensionless): 0.879711
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709598
 - hLp in component INaL (dimensionless): 0.451715
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.621329
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.696190
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935420
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999886
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001606
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.332854
 - xs1 in component IKs (dimensionless): 0.241033
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997341
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
00:37:45 (16838): called boinc_finish(0)

</stderr_txt>
]]>