𝕏

Task 55711828

Name HuVeMOp_20240630085547551318_ORdGradInc_k_25-Pueyo_APDR-conf_319_3
Workunit 26310139
Created 2 Jul 2024, 12:14:51 UTC
Sent 2 Jul 2024, 14:24:10 UTC
Report deadline 6 Jul 2024, 0:00:10 UTC
Received 5 Jul 2024, 16:57:16 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 222504
Run time 1 hours 39 min 56 sec
CPU time 1 hours 20 min 36 sec
Validate state Valid
Credit 59.65
Device peak FLOPS 4.76 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 7.85 MB
Peak swap size 32.86 GB
Peak disk usage 0.26 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630085547551318_ORdGradInc_k_25-Pueyo_APDR-conf_319.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630085547551318_ORdGradInc_k_25-Pueyo_APDR-conf_319_3_r810337306_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630085547551318_ORdGradInc_k_25-Pueyo_APDR-conf_319_3_r810337306_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 96.057462
     * GNaL_b in INaL: 0.006700
     * Gto_b in Ito: 0.093167
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032954
     * GKs_b in IKs: 0.001958
     * GK1_b in IK1: 0.149530
     * Gncx_b in INaCa_i: 0.000979
     * Pnak_b in INaK: 75.277227
     * GKb_b in IKb: 0.003903
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.053985
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 18585149, states[0] = -7.668768, states[40]= 0.002755
Saving checkpoint... 
Iteration: 38002483, states[0] = 38.629661, states[40]= 0.118864
Saving checkpoint... 
Iteration: 57076122, states[0] = 0.263780, states[40]= 0.004142
Saving checkpoint... 
Iteration: 77857709, states[0] = -94.905142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98962102, states[0] = -94.928045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119687335, states[0] = -94.682949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 140903818, states[0] = -94.909399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 160655319, states[0] = -75.386696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 181801185, states[0] = -94.856297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 200440340, states[0] = -94.916589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 220239615, states[0] = -94.786806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 238352383, states[0] = -94.887862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 256300368, states[0] = -94.855042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 277017041, states[0] = 21.282203, states[40]= 0.012970
Saving checkpoint... 
Iteration: 295804242, states[0] = -94.858048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314124921, states[0] = -40.568706, states[40]= 0.000113
Saving checkpoint... 
Iteration: 332083451, states[0] = -3.405349, states[40]= 0.003569
Saving checkpoint... 
Iteration: 351088641, states[0] = -7.122748, states[40]= 0.002838
Saving checkpoint... 
Iteration: 369894044, states[0] = -94.904138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 389990493, states[0] = -94.924319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 410316133, states[0] = -94.866674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 428717941, states[0] = -94.750178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448392436, states[0] = -94.903566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 469131630, states[0] = -47.440854, states[40]= 0.000040
Saving checkpoint... 
Iteration: 488355665, states[0] = -94.889148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507726370, states[0] = -94.765096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 526778959, states[0] = -94.835417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 545247401, states[0] = -94.797728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 564979240, states[0] = -94.922700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 585105049, states[0] = -21.754157, states[40]= 0.000834
Saving checkpoint... 
Iteration: 600917285, states[0] = -94.910677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 616827138, states[0] = -94.873729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 633211223, states[0] = -94.737373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 650742921, states[0] = -94.791255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 668980484, states[0] = -94.922810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686070370, states[0] = 3.771686, states[40]= 0.004453
Saving checkpoint... 
Iteration: 702316913, states[0] = -94.867025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 718629642, states[0] = -45.361763, states[40]= 0.000055
Saving checkpoint... 
Iteration: 736319307, states[0] = -94.868622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755441500, states[0] = -94.916133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 774148605, states[0] = -66.285108, states[40]= 0.000002
Saving checkpoint... 
Iteration: 791900447, states[0] = -94.905863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 808650392, states[0] = -68.514061, states[40]= 0.000001
Saving checkpoint... 
Iteration: 824805762, states[0] = -94.858869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842613266, states[0] = -29.413101, states[40]= 0.000478
Saving checkpoint... 
Iteration: 860219851, states[0] = -94.753389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 877041599, states[0] = 15.045089, states[40]= 0.004919
Saving checkpoint... 
Iteration: 893901628, states[0] = -94.906153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 911855818, states[0] = -94.888952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932039889, states[0] = 15.626662, states[40]= 0.004984
Saving checkpoint... 
Iteration: 952192645, states[0] = -94.697233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 972504704, states[0] = 27.321278, states[40]= 0.150375
Saving checkpoint... 
Iteration: 991757821, states[0] = -94.811264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012624220, states[0] = -39.873729, states[40]= 0.000125
Saving checkpoint... 
Iteration: 1032469386, states[0] = -94.920942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1050489827, states[0] = -94.923817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1071433544, states[0] = -94.914249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1091653015, states[0] = -71.988889, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1111770894, states[0] = -94.826554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1131249741, states[0] = -94.800588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1152075010, states[0] = 1.494689, states[40]= 0.004259
Saving checkpoint... 
Iteration: 1172216831, states[0] = -94.747656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193141583, states[0] = -58.191221, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1213920189, states[0] = -94.911027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234668306, states[0] = -92.336441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253795152, states[0] = -94.850010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1273277904, states[0] = -94.833873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1292408840, states[0] = -94.907982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1311818487, states[0] = -94.867709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328973140, states[0] = -94.921330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1348791308, states[0] = -94.846600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368069768, states[0] = 4.051864, states[40]= 0.004472
Saving checkpoint... 
Iteration: 1386930305, states[0] = -94.913327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1405720516, states[0] = -94.754243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424288604, states[0] = -94.844116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443653598, states[0] = -72.799324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1463597378, states[0] = -14.627621, states[40]= 0.001463
Saving checkpoint... 
Iteration: 1482999154, states[0] = -94.924680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1502977688, states[0] = -95.154417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1521898490, states[0] = -95.198504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1541911231, states[0] = -95.120437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1560972401, states[0] = -6.687370, states[40]= 0.003329
Saving checkpoint... 
Iteration: 1579151031, states[0] = -95.193256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1598413812, states[0] = 21.868818, states[40]= 0.023859
Saving checkpoint... 
Iteration: 1617341805, states[0] = 11.878197, states[40]= 0.005705
Saving checkpoint... 
Iteration: 1636130064, states[0] = -95.172195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1655973613, states[0] = -95.221702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1675315543, states[0] = -54.281910, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1695095735, states[0] = -31.613660, states[40]= 0.000372
Saving checkpoint... 
Iteration: 1715150151, states[0] = 7.703140, states[40]= 0.005370
Saving checkpoint... 
Iteration: 1735338987, states[0] = -88.181131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1755622689, states[0] = 19.633217, states[40]= 0.008750
Saving checkpoint... 
Iteration: 1774481817, states[0] = -95.228951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1794913641, states[0] = 21.882966, states[40]= 0.024600
Saving checkpoint... 
Iteration: 1812270152, states[0] = -94.880851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1829857005, states[0] = -94.923398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1847682222, states[0] = -94.663560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1864887579, states[0] = -94.912772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1882808783, states[0] = -94.867241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1900865991, states[0] = -94.896671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1920455869, states[0] = -94.920212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1940122459, states[0] = -38.207036, states[40]= 0.000159
Saving checkpoint... 
Iteration: 1960851761, states[0] = -94.886930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1982223588, states[0] = -94.759608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2003801789, states[0] = -94.855126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2025763742, states[0] = -94.817854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2048236234, states[0] = -94.780246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2071263532, states[0] = -94.817512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2093775740, states[0] = -94.831072, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.800215
 - CaMKt in component CaMK (millimolar): 0.006825
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.478108
 - nass in component intracellular_ions (millimolar): 6.478167
 - ki in component intracellular_ions (millimolar): 145.504074
 - kss in component intracellular_ions (millimolar): 145.504054
 - cansr in component intracellular_ions (millimolar): 1.290781
 - cajsr in component intracellular_ions (millimolar): 1.252526
 - cai in component intracellular_ions (millimolar): 0.000073
 - m in component INa (dimensionless): 0.003656
 - hf in component INa (dimensionless): 0.878226
 - hs in component INa (dimensionless): 0.878221
 - j in component INa (dimensionless): 0.878192
 - hsp in component INa (dimensionless): 0.722494
 - jp in component INa (dimensionless): 0.878172
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.706294
 - hLp in component INaL (dimensionless): 0.446142
 - a in component Ito (dimensionless): 0.000628
 - iF in component Ito (dimensionless): 0.999867
 - iS in component Ito (dimensionless): 0.617088
 - ap in component Ito (dimensionless): 0.000320
 - iFp in component Ito (dimensionless): 0.999867
 - iSp in component Ito (dimensionless): 0.691098
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934171
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999881
 - jca in component ICaL (dimensionless): 0.999976
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001504
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.326521
 - xs1 in component IKs (dimensionless): 0.246616
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997364
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
00:56:58 (17129): called boinc_finish(0)

</stderr_txt>
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