𝕏

Task 55711826

Name HuVeMOp_20240630085547551318_ORdGradInc_k_25-Pueyo_APDR-conf_19_3
Workunit 26310137
Created 2 Jul 2024, 12:14:51 UTC
Sent 2 Jul 2024, 14:24:10 UTC
Report deadline 6 Jul 2024, 0:00:10 UTC
Received 5 Jul 2024, 17:17:43 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 222504
Run time 1 hours 38 min 8 sec
CPU time 1 hours 20 min
Validate state Valid
Credit 59.97
Device peak FLOPS 4.76 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 8.01 MB
Peak swap size 32.86 GB
Peak disk usage 0.26 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630085547551318_ORdGradInc_k_25-Pueyo_APDR-conf_19.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630085547551318_ORdGradInc_k_25-Pueyo_APDR-conf_19_3_r1074333505_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630085547551318_ORdGradInc_k_25-Pueyo_APDR-conf_19_3_r1074333505_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 107.417585
     * GNaL_b in INaL: 0.006505
     * Gto_b in Ito: 0.084128
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.029652
     * GKs_b in IKs: 0.001759
     * GK1_b in IK1: 0.165974
     * Gncx_b in INaCa_i: 0.000972
     * Pnak_b in INaK: 68.083405
     * GKb_b in IKb: 0.003786
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.026227
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 18969074, states[0] = -95.024367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40293456, states[0] = -94.925584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 60671557, states[0] = -92.697343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 80097690, states[0] = -12.801723, states[40]= 0.001790
Saving checkpoint... 
Iteration: 99554166, states[0] = 11.171000, states[40]= 0.004931
Saving checkpoint... 
Iteration: 119679521, states[0] = -94.493008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 139196961, states[0] = -94.762801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 159860435, states[0] = -94.943002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 179026563, states[0] = 20.349267, states[40]= 0.006677
Saving checkpoint... 
Iteration: 196937441, states[0] = -94.967061, states[40]= 0.000000
Saving checkpoint... 
Iteration: 214469391, states[0] = -94.972982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 231068596, states[0] = 5.459945, states[40]= 0.004720
Saving checkpoint... 
Iteration: 249276585, states[0] = -94.884046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 266322059, states[0] = -94.921406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 282585336, states[0] = -3.172546, states[40]= 0.003714
Saving checkpoint... 
Iteration: 299574288, states[0] = 2.860201, states[40]= 0.004531
Saving checkpoint... 
Iteration: 317234737, states[0] = -94.830607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 335165323, states[0] = -83.717791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 353915862, states[0] = -94.961497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 371035899, states[0] = 17.659767, states[40]= 0.005468
Saving checkpoint... 
Iteration: 388586659, states[0] = -4.020730, states[40]= 0.003554
Saving checkpoint... 
Iteration: 405685247, states[0] = -94.697623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422343715, states[0] = -94.933959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439666200, states[0] = -85.201432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 456150750, states[0] = -62.416694, states[40]= 0.000004
Saving checkpoint... 
Iteration: 475586698, states[0] = -4.046193, states[40]= 0.003549
Saving checkpoint... 
Iteration: 493130326, states[0] = -41.237768, states[40]= 0.000118
Saving checkpoint... 
Iteration: 512725910, states[0] = -94.816182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 533810616, states[0] = -94.913324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554916386, states[0] = -94.961504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 574976532, states[0] = -94.973718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594212072, states[0] = -94.791491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 614356808, states[0] = -94.940311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 633259746, states[0] = -94.864918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 652595894, states[0] = -10.889175, states[40]= 0.002130
Saving checkpoint... 
Iteration: 673248645, states[0] = -94.850612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 693721890, states[0] = -94.809182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 714243068, states[0] = -94.842793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 734522144, states[0] = 21.372025, states[40]= 0.008232
Saving checkpoint... 
Iteration: 756348233, states[0] = -94.936070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 777989615, states[0] = -94.975452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 798697242, states[0] = -94.761626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819154859, states[0] = -67.421147, states[40]= 0.000002
Saving checkpoint... 
Iteration: 838975651, states[0] = -94.973413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 858455344, states[0] = -94.969982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 877537672, states[0] = 17.086567, states[40]= 0.005354
Saving checkpoint... 
Iteration: 897664066, states[0] = -81.531461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 916513858, states[0] = 22.776220, states[40]= 0.022902
Saving checkpoint... 
Iteration: 934729736, states[0] = -94.822241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953975249, states[0] = -94.973277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 973185277, states[0] = -94.697688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992486261, states[0] = -94.974857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011249985, states[0] = -94.852201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1029563281, states[0] = 7.701135, states[40]= 0.004825
Saving checkpoint... 
Iteration: 1048442834, states[0] = -94.967407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067394384, states[0] = -94.954695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1086239882, states[0] = -94.837906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1105218323, states[0] = -94.802615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124399769, states[0] = -94.956369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1144611261, states[0] = -24.186905, states[40]= 0.000806
Saving checkpoint... 
Iteration: 1162880150, states[0] = -94.949675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1181740842, states[0] = -94.839259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1200927579, states[0] = -94.963907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1219524153, states[0] = 20.933730, states[40]= 0.007363
Saving checkpoint... 
Iteration: 1239803309, states[0] = -94.907350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258761539, states[0] = -94.866673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277624119, states[0] = -35.523260, states[40]= 0.000266
Saving checkpoint... 
Iteration: 1298316617, states[0] = -94.917069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1317687829, states[0] = -94.725228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338263004, states[0] = -94.868357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1357741487, states[0] = -94.840088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1378496418, states[0] = -94.975947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1398275360, states[0] = -94.881981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1416106456, states[0] = -19.995328, states[40]= 0.001002
Saving checkpoint... 
Iteration: 1432727978, states[0] = -94.819033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1451026616, states[0] = 20.341009, states[40]= 0.006666
Saving checkpoint... 
Iteration: 1468635759, states[0] = -46.512108, states[40]= 0.000053
Saving checkpoint... 
Iteration: 1487471166, states[0] = -94.972294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1506814800, states[0] = -95.108436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1525108851, states[0] = -95.114028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1543865238, states[0] = 0.680958, states[40]= 0.004873
Saving checkpoint... 
Iteration: 1566233063, states[0] = -95.173817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1588950210, states[0] = -93.985414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1611075001, states[0] = -7.065126, states[40]= 0.003325
Saving checkpoint... 
Iteration: 1632030506, states[0] = 17.713373, states[40]= 0.007012
Saving checkpoint... 
Iteration: 1654888951, states[0] = -20.784451, states[40]= 0.001007
Saving checkpoint... 
Iteration: 1677382266, states[0] = -14.020732, states[40]= 0.001809
Saving checkpoint... 
Iteration: 1700444052, states[0] = 11.690356, states[40]= 0.005887
Saving checkpoint... 
Iteration: 1722750163, states[0] = -94.060870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1744792522, states[0] = -95.241406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1767730564, states[0] = -67.107266, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1788054672, states[0] = 6.352275, states[40]= 0.005471
Saving checkpoint... 
Iteration: 1805663349, states[0] = -87.749968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1824874648, states[0] = -94.978417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1844289690, states[0] = -94.913654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1862875865, states[0] = -94.957994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1880755672, states[0] = -94.865296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1899827250, states[0] = -94.927105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1920709877, states[0] = -94.788387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1941946009, states[0] = -94.968458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1963483124, states[0] = -94.974285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1985072321, states[0] = 3.780934, states[40]= 0.004608
Saving checkpoint... 
Iteration: 2006918836, states[0] = -94.961308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2029459872, states[0] = -94.970068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2052236409, states[0] = -94.832034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2074897898, states[0] = -94.955134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2096917063, states[0] = -94.960641, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.851752
 - CaMKt in component CaMK (millimolar): 0.007180
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.662636
 - nass in component intracellular_ions (millimolar): 6.662696
 - ki in component intracellular_ions (millimolar): 145.313150
 - kss in component intracellular_ions (millimolar): 145.313132
 - cansr in component intracellular_ions (millimolar): 1.320274
 - cajsr in component intracellular_ions (millimolar): 1.281440
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003637
 - hf in component INa (dimensionless): 0.879129
 - hs in component INa (dimensionless): 0.879124
 - j in component INa (dimensionless): 0.879093
 - hsp in component INa (dimensionless): 0.724188
 - jp in component INa (dimensionless): 0.879073
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.706484
 - hLp in component INaL (dimensionless): 0.444400
 - a in component Ito (dimensionless): 0.000626
 - iF in component Ito (dimensionless): 0.999868
 - iS in component Ito (dimensionless): 0.612286
 - ap in component Ito (dimensionless): 0.000319
 - iFp in component Ito (dimensionless): 0.999868
 - iSp in component Ito (dimensionless): 0.685384
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.929881
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999863
 - jca in component ICaL (dimensionless): 0.999974
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001635
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.344614
 - xs1 in component IKs (dimensionless): 0.253508
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997350
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
01:17:25 (17933): called boinc_finish(0)

</stderr_txt>
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