𝕏

Task 55711820

Name HuVeMOp_20240630080230729127_ORdGradInc_k_25-Pueyo_APDR-conf_879_3
Workunit 26309599
Created 2 Jul 2024, 12:14:51 UTC
Sent 2 Jul 2024, 14:24:10 UTC
Report deadline 6 Jul 2024, 0:00:10 UTC
Received 5 Jul 2024, 16:34:01 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 222504
Run time 1 hours 43 min 40 sec
CPU time 1 hours 21 min 54 sec
Validate state Valid
Credit 60.30
Device peak FLOPS 4.76 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 6.75 MB
Peak swap size 32.86 GB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630080230729127_ORdGradInc_k_25-Pueyo_APDR-conf_879.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630080230729127_ORdGradInc_k_25-Pueyo_APDR-conf_879_3_r1911999846_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630080230729127_ORdGradInc_k_25-Pueyo_APDR-conf_879_3_r1911999846_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 97.245512
     * GNaL_b in INaL: 0.006491
     * Gto_b in Ito: 0.087035
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030177
     * GKs_b in IKs: 0.002108
     * GK1_b in IK1: 0.160875
     * Gncx_b in INaCa_i: 0.000974
     * Pnak_b in INaK: 74.771832
     * GKb_b in IKb: 0.003766
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.022400
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 25349499, states[0] = -94.934210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 49431864, states[0] = -94.926618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 74220886, states[0] = -94.743865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98390663, states[0] = -94.890926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 125150718, states[0] = -62.504791, states[40]= 0.000003
Saving checkpoint... 
Iteration: 150766584, states[0] = -94.800237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 177372773, states[0] = -94.877945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 203731465, states[0] = -94.748640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 228832175, states[0] = -94.856550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 254298491, states[0] = -94.831598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279995629, states[0] = -94.907972, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630080230729127_ORdGradInc_k_25-Pueyo_APDR-conf_879.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630080230729127_ORdGradInc_k_25-Pueyo_APDR-conf_879_3_r1911999846_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630080230729127_ORdGradInc_k_25-Pueyo_APDR-conf_879_3_r1911999846_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 97.245512
     * GNaL_b in INaL: 0.006491
     * Gto_b in Ito: 0.087035
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030177
     * GKs_b in IKs: 0.002108
     * GK1_b in IK1: 0.160875
     * Gncx_b in INaCa_i: 0.000974
     * Pnak_b in INaK: 74.771832
     * GKb_b in IKb: 0.003766
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.022400
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 279995629
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.907972 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 296556527, states[0] = 10.405185, states[40]= 0.004822
Saving checkpoint... 
Iteration: 314601025, states[0] = -15.332814, states[40]= 0.001403
Saving checkpoint... 
Iteration: 332562269, states[0] = 8.162737, states[40]= 0.004772
Saving checkpoint... 
Iteration: 350439071, states[0] = -94.897991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367352707, states[0] = -94.867912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382656111, states[0] = -68.741450, states[40]= 0.000001
Saving checkpoint... 
Iteration: 399528915, states[0] = 19.682969, states[40]= 0.005982
Saving checkpoint... 
Iteration: 416887585, states[0] = -94.883002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 433607234, states[0] = -20.792293, states[40]= 0.000945
Saving checkpoint... 
Iteration: 450953936, states[0] = -94.901055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470103705, states[0] = -17.686909, states[40]= 0.001155
Saving checkpoint... 
Iteration: 490050440, states[0] = 12.664402, states[40]= 0.004866
Saving checkpoint... 
Iteration: 509109550, states[0] = -22.823854, states[40]= 0.000851
Saving checkpoint... 
Iteration: 530388501, states[0] = -94.883258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 552148291, states[0] = -59.593686, states[40]= 0.000006
Saving checkpoint... 
Iteration: 572467435, states[0] = -94.903464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593113633, states[0] = -26.400720, states[40]= 0.000691
Saving checkpoint... 
Iteration: 614191495, states[0] = -94.661127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634361014, states[0] = -94.871799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 652694097, states[0] = -94.671593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672433007, states[0] = -94.896359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 689878943, states[0] = -94.879521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 707952127, states[0] = -94.900521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728492176, states[0] = -94.907175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 747716493, states[0] = -94.720988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 766048803, states[0] = 13.255902, states[40]= 0.004883
Saving checkpoint... 
Iteration: 784328449, states[0] = -94.853683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803157753, states[0] = -70.921973, states[40]= 0.000001
Saving checkpoint... 
Iteration: 822477404, states[0] = -94.904941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842145273, states[0] = -56.370873, states[40]= 0.000010
Saving checkpoint... 
Iteration: 862707288, states[0] = -94.702735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 881487980, states[0] = -94.906485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 901556239, states[0] = 10.514890, states[40]= 0.004824
Saving checkpoint... 
Iteration: 922374852, states[0] = -94.877706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940628191, states[0] = -39.403207, states[40]= 0.000152
Saving checkpoint... 
Iteration: 960379266, states[0] = -94.879464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980287318, states[0] = -94.820764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 999721305, states[0] = -94.729852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019586629, states[0] = -3.990134, states[40]= 0.003531
Saving checkpoint... 
Iteration: 1039264204, states[0] = -94.795378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056602387, states[0] = -16.526797, states[40]= 0.001266
Saving checkpoint... 
Iteration: 1074832437, states[0] = -94.856009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090892784, states[0] = -94.884398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110581647, states[0] = -0.938606, states[40]= 0.004048
Saving checkpoint... 
Iteration: 1127384357, states[0] = -94.881318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1145946159, states[0] = -94.898995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1161763583, states[0] = -94.794528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1179005587, states[0] = 26.523644, states[40]= 0.138936
Saving checkpoint... 
Iteration: 1197256703, states[0] = -94.785683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215632752, states[0] = -43.711886, states[40]= 0.000080
Saving checkpoint... 
Iteration: 1231628490, states[0] = -39.680199, states[40]= 0.000146
Saving checkpoint... 
Iteration: 1246131807, states[0] = -42.804259, states[40]= 0.000092
Saving checkpoint... 
Iteration: 1261825370, states[0] = -94.851340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278257917, states[0] = -94.787228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1295922104, states[0] = -94.893190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312409919, states[0] = -94.889762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1329135705, states[0] = -46.598170, states[40]= 0.000051
Saving checkpoint... 
Iteration: 1347179251, states[0] = -94.257613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1364679999, states[0] = -94.337297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385016821, states[0] = 22.100816, states[40]= 0.013333
Saving checkpoint... 
Iteration: 1405366466, states[0] = -94.873774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425917941, states[0] = -94.891977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1445635524, states[0] = -46.419082, states[40]= 0.000053
Saving checkpoint... 
Iteration: 1464935499, states[0] = -94.896408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1484241183, states[0] = -94.763220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1502089930, states[0] = -95.121018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1521782789, states[0] = -94.992251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1541623093, states[0] = -95.088457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1560818521, states[0] = -95.089979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1580522098, states[0] = -56.101077, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1602194134, states[0] = -95.050895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1623355478, states[0] = 5.928609, states[40]= 0.005363
Saving checkpoint... 
Iteration: 1643529472, states[0] = -65.549563, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1664077332, states[0] = -95.172413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1684245962, states[0] = 10.751379, states[40]= 0.005689
Saving checkpoint... 
Iteration: 1703157010, states[0] = 5.073971, states[40]= 0.005300
Saving checkpoint... 
Iteration: 1721642188, states[0] = -95.135014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1740644349, states[0] = 11.524490, states[40]= 0.005750
Saving checkpoint... 
Iteration: 1758845338, states[0] = -95.139010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1776555493, states[0] = -95.150974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1796804583, states[0] = -36.964034, states[40]= 0.000213
Saving checkpoint... 
Iteration: 1815772065, states[0] = -94.845681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1834653789, states[0] = -68.016597, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1852671876, states[0] = -92.233317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1871423102, states[0] = -94.901067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1890330364, states[0] = -94.858643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1909839269, states[0] = -94.861991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1928458246, states[0] = -94.902238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1948856838, states[0] = -94.869602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1967413133, states[0] = -94.890630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1986827420, states[0] = -94.852377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2005272661, states[0] = -94.804767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2023718396, states[0] = -94.723744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2042431222, states[0] = -94.894980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2060861486, states[0] = -94.871013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2079503365, states[0] = 34.043876, states[40]= 0.154066
Saving checkpoint... 
Iteration: 2098791231, states[0] = -94.823680, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.783096
 - CaMKt in component CaMK (millimolar): 0.007186
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.506046
 - nass in component intracellular_ions (millimolar): 6.506106
 - ki in component intracellular_ions (millimolar): 145.469650
 - kss in component intracellular_ions (millimolar): 145.469631
 - cansr in component intracellular_ions (millimolar): 1.318911
 - cajsr in component intracellular_ions (millimolar): 1.279986
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003662
 - hf in component INa (dimensionless): 0.877925
 - hs in component INa (dimensionless): 0.877920
 - j in component INa (dimensionless): 0.877888
 - hsp in component INa (dimensionless): 0.721927
 - jp in component INa (dimensionless): 0.877866
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.704527
 - hLp in component INaL (dimensionless): 0.441978
 - a in component Ito (dimensionless): 0.000628
 - iF in component Ito (dimensionless): 0.999867
 - iS in component Ito (dimensionless): 0.611716
 - ap in component Ito (dimensionless): 0.000320
 - iFp in component Ito (dimensionless): 0.999867
 - iSp in component Ito (dimensionless): 0.684679
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.930209
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999866
 - jca in component ICaL (dimensionless): 0.999974
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001627
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.339280
 - xs1 in component IKs (dimensionless): 0.253346
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997368
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
00:33:44 (16837): called boinc_finish(0)

</stderr_txt>
]]>