𝕏

Task 55711460

Name HuVeMOp_20240629110615760215_ORdGradInc_k_25-Drouin_MID_4000-conf_503_2
Workunit 26239608
Created 2 Jul 2024, 10:37:14 UTC
Sent 2 Jul 2024, 14:22:09 UTC
Report deadline 5 Jul 2024, 14:22:09 UTC
Received 3 Jul 2024, 5:48:50 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 216894
Run time 2 hours 33 min 32 sec
CPU time 1 hours 58 min 8 sec
Validate state Valid
Credit 44.36
Device peak FLOPS 4.93 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.68 MB
Peak swap size 32.60 GB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.22.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Drouin_MID_4000-conf_503.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Drouin_MID_4000-conf_503_2_r1560357326_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Drouin_MID_4000-conf_503_2_r1560357326_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 98.555952
     * GNaL_b in INaL: 0.007078
     * Gto_b in Ito: 0.089492
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032108
     * GKs_b in IKs: 0.002069
     * GK1_b in IK1: 0.153753
     * Gncx_b in INaCa_i: 0.000958
     * Pnak_b in INaK: 71.867170
     * GKb_b in IKb: 0.003859
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.045573
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 7755632, states[0] = -94.037369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 18597303, states[0] = -94.002750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 29660138, states[0] = -94.020676, states[40]= 0.000001
Saving checkpoint... 
Iteration: 40656122, states[0] = -94.045194, states[40]= 0.000001
Saving checkpoint... 
Iteration: 51545888, states[0] = -94.048418, states[40]= 0.000001
Saving checkpoint... 
Iteration: 62384965, states[0] = -93.822753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 71976061, states[0] = -94.058160, states[40]= 0.000001
Saving checkpoint... 
Iteration: 82754050, states[0] = -94.093409, states[40]= 0.000001
Saving checkpoint... 
Iteration: 93720050, states[0] = -94.074688, states[40]= 0.000001
Saving checkpoint... 
Iteration: 104677652, states[0] = -94.096566, states[40]= 0.000001
Saving checkpoint... 
Iteration: 115216820, states[0] = -94.095684, states[40]= 0.000001
Saving checkpoint... 
Iteration: 125762032, states[0] = -94.083226, states[40]= 0.000001
Saving checkpoint... 
Iteration: 136444290, states[0] = -93.979916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147112505, states[0] = -94.104661, states[40]= 0.000001
Saving checkpoint... 
Iteration: 157827724, states[0] = -94.085956, states[40]= 0.000001
Saving checkpoint... 
Iteration: 168395479, states[0] = -93.898801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 175574959, states[0] = -94.092038, states[40]= 0.000001
Saving checkpoint... 
Iteration: 185682365, states[0] = -94.089996, states[40]= 0.000001
Saving checkpoint... 
Iteration: 196559218, states[0] = -94.077082, states[40]= 0.000001
Saving checkpoint... 
Iteration: 206408578, states[0] = -93.927323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 214399570, states[0] = -93.909338, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Drouin_MID_4000-conf_503.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Drouin_MID_4000-conf_503_2_r1560357326_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240629110615760215_ORdGradInc_k_25-Drouin_MID_4000-conf_503_2_r1560357326_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 98.555952
     * GNaL_b in INaL: 0.007078
     * Gto_b in Ito: 0.089492
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032108
     * GKs_b in IKs: 0.002069
     * GK1_b in IK1: 0.153753
     * Gncx_b in INaCa_i: 0.000958
     * Pnak_b in INaK: 71.867170
     * GKb_b in IKb: 0.003859
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.045573
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 214399570
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -93.909338 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 226324732, states[0] = -93.670816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 237652059, states[0] = -94.091124, states[40]= 0.000001
Saving checkpoint... 
Iteration: 248370705, states[0] = -93.838671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 258235284, states[0] = -46.982763, states[40]= 0.000907
Saving checkpoint... 
Iteration: 268232970, states[0] = -45.280900, states[40]= 0.001137
Saving checkpoint... 
Iteration: 278125266, states[0] = 6.026983, states[40]= 0.000115
Saving checkpoint... 
Iteration: 288607571, states[0] = -94.093840, states[40]= 0.000001
Saving checkpoint... 
Iteration: 299229176, states[0] = -94.102634, states[40]= 0.000001
Saving checkpoint... 
Iteration: 309933120, states[0] = -94.085565, states[40]= 0.000001
Saving checkpoint... 
Iteration: 320397180, states[0] = -93.903788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 329941540, states[0] = -94.085218, states[40]= 0.000001
Saving checkpoint... 
Iteration: 340454537, states[0] = -93.997168, states[40]= 0.000001
Saving checkpoint... 
Iteration: 350997453, states[0] = -94.110446, states[40]= 0.000001
Saving checkpoint... 
Iteration: 361468687, states[0] = -94.094390, states[40]= 0.000001
Saving checkpoint... 
Iteration: 371849650, states[0] = -94.086099, states[40]= 0.000001
Saving checkpoint... 
Iteration: 382457264, states[0] = -93.999905, states[40]= 0.000001
Saving checkpoint... 
Iteration: 392444478, states[0] = -93.983757, states[40]= 0.000001
Saving checkpoint... 
Iteration: 402166684, states[0] = -13.538715, states[40]= 0.000770
Saving checkpoint... 
Iteration: 412086350, states[0] = 20.601650, states[40]= 0.000003
Saving checkpoint... 
Iteration: 421626623, states[0] = -94.089736, states[40]= 0.000001
Saving checkpoint... 
Iteration: 430757230, states[0] = -94.111809, states[40]= 0.000001
Saving checkpoint... 
Iteration: 441197858, states[0] = -94.102033, states[40]= 0.000001
Saving checkpoint... 
Iteration: 452153251, states[0] = -5.984053, states[40]= 0.000572
Saving checkpoint... 
Iteration: 463180426, states[0] = -94.102390, states[40]= 0.000001
Saving checkpoint... 
Iteration: 473231346, states[0] = -94.100439, states[40]= 0.000001
Saving checkpoint... 
Iteration: 482684980, states[0] = -94.105795, states[40]= 0.000001
Saving checkpoint... 
Iteration: 491687809, states[0] = -94.087550, states[40]= 0.000001
Saving checkpoint... 
Iteration: 500802151, states[0] = -94.112063, states[40]= 0.000001
Saving checkpoint... 
Iteration: 510113155, states[0] = 10.609659, states[40]= 0.000043
Saving checkpoint... 
Iteration: 519351128, states[0] = -94.095864, states[40]= 0.000001
Saving checkpoint... 
Iteration: 529622234, states[0] = -94.088476, states[40]= 0.000001
Saving checkpoint... 
Iteration: 540794567, states[0] = -94.111455, states[40]= 0.000001
Saving checkpoint... 
Iteration: 551812714, states[0] = -94.084454, states[40]= 0.000001
Saving checkpoint... 
Iteration: 562534598, states[0] = -94.061506, states[40]= 0.000001
Saving checkpoint... 
Iteration: 573230439, states[0] = -94.099212, states[40]= 0.000001
Saving checkpoint... 
Iteration: 583812729, states[0] = -94.084049, states[40]= 0.000001
Saving checkpoint... 
Iteration: 594296856, states[0] = -93.517016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 604799173, states[0] = -94.110718, states[40]= 0.000001
Saving checkpoint... 
Iteration: 615153805, states[0] = -94.101450, states[40]= 0.000001
Saving checkpoint... 
Iteration: 624985825, states[0] = -94.107404, states[40]= 0.000001
Saving checkpoint... 
Iteration: 632080964, states[0] = 22.535258, states[40]= 0.000002
Saving checkpoint... 
Iteration: 642159536, states[0] = -9.418908, states[40]= 0.000648
Saving checkpoint... 
Iteration: 651337272, states[0] = -94.094639, states[40]= 0.000001
Saving checkpoint... 
Iteration: 659977699, states[0] = -94.080591, states[40]= 0.000001
Saving checkpoint... 
Iteration: 669031549, states[0] = -94.105272, states[40]= 0.000001
Saving checkpoint... 
Iteration: 678503149, states[0] = -94.039642, states[40]= 0.000001
Saving checkpoint... 
Iteration: 688773760, states[0] = -94.109131, states[40]= 0.000001
Saving checkpoint... 
Iteration: 699466861, states[0] = -94.090193, states[40]= 0.000001
Saving checkpoint... 
Iteration: 710526385, states[0] = -94.054890, states[40]= 0.000001
Saving checkpoint... 
Iteration: 721656590, states[0] = -94.085303, states[40]= 0.000001
Saving checkpoint... 
Iteration: 732636116, states[0] = -94.095041, states[40]= 0.000001
Saving checkpoint... 
Iteration: 743635003, states[0] = -94.085495, states[40]= 0.000001
Saving checkpoint... 
Iteration: 754635260, states[0] = -94.094596, states[40]= 0.000001
Saving checkpoint... 
Iteration: 764560047, states[0] = -94.071484, states[40]= 0.000001
Saving checkpoint... 
Iteration: 775305010, states[0] = -94.094128, states[40]= 0.000001
Saving checkpoint... 
Iteration: 782647516, states[0] = -94.096577, states[40]= 0.000001
Saving checkpoint... 
Iteration: 793410666, states[0] = -94.090609, states[40]= 0.000001
Saving checkpoint... 
Iteration: 800205306, states[0] = -28.926438, states[40]= 0.005746
Saving checkpoint... 
Iteration: 809042609, states[0] = -94.103117, states[40]= 0.000001
Saving checkpoint... 
Iteration: 818673883, states[0] = -94.100193, states[40]= 0.000001
Saving checkpoint... 
Iteration: 827974593, states[0] = -94.078519, states[40]= 0.000001
Saving checkpoint... 
Iteration: 837310431, states[0] = -94.093169, states[40]= 0.000001
Saving checkpoint... 
Iteration: 846399621, states[0] = -93.902321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 856064252, states[0] = 28.087318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 866239555, states[0] = -50.225044, states[40]= 0.000578
Saving checkpoint... 
Iteration: 877254920, states[0] = -94.094535, states[40]= 0.000001
Saving checkpoint... 
Iteration: 888890596, states[0] = -94.106685, states[40]= 0.000001
Saving checkpoint... 
Iteration: 899742945, states[0] = -94.081326, states[40]= 0.000001
Saving checkpoint... 
Iteration: 910130203, states[0] = 4.127896, states[40]= 0.000166
Saving checkpoint... 
Iteration: 921017238, states[0] = -94.102612, states[40]= 0.000001
Saving checkpoint... 
Iteration: 932015529, states[0] = 31.283218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 943023156, states[0] = -94.102126, states[40]= 0.000001
Saving checkpoint... 
Iteration: 953918382, states[0] = -94.077717, states[40]= 0.000001
Saving checkpoint... 
Iteration: 964746305, states[0] = -94.104609, states[40]= 0.000001
Saving checkpoint... 
Iteration: 975574915, states[0] = -94.083951, states[40]= 0.000001
Saving checkpoint... 
Iteration: 986349035, states[0] = -93.760435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 996808615, states[0] = -94.105896, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1006344092, states[0] = -93.742067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1015654889, states[0] = -94.081638, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1024886220, states[0] = -94.105055, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1034691384, states[0] = -94.099564, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1045028238, states[0] = -94.100661, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1054998091, states[0] = -94.101586, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1066388881, states[0] = -93.875629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1077313333, states[0] = -94.090051, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1088085281, states[0] = 20.992284, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1098828605, states[0] = -94.104696, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1109373298, states[0] = -94.087748, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1119942942, states[0] = -94.075270, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1130439384, states[0] = -93.967416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1140981534, states[0] = -94.101056, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1151476184, states[0] = -94.084248, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1160781908, states[0] = -94.103408, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1169688665, states[0] = -94.078989, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1178687935, states[0] = -94.097373, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1188189620, states[0] = -23.248941, states[40]= 0.004947
Saving checkpoint... 
Iteration: 1196994748, states[0] = -94.099911, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1205491089, states[0] = -94.083167, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1215120332, states[0] = -94.095139, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1225150104, states[0] = -94.093910, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1232432658, states[0] = -93.956344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1242763657, states[0] = -94.101840, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1253113721, states[0] = -94.094905, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1263305980, states[0] = -94.087948, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1273425553, states[0] = -94.084127, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1283584851, states[0] = -94.079834, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1293967532, states[0] = -94.072737, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1303923606, states[0] = -94.073226, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1312962414, states[0] = -94.099498, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1321773742, states[0] = -94.075434, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1330068432, states[0] = 26.788989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1339224057, states[0] = -94.089794, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1349123192, states[0] = -94.093346, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1359340298, states[0] = -94.085632, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1369493295, states[0] = -94.081045, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1378566542, states[0] = -94.066473, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1388119724, states[0] = 8.136649, states[40]= 0.000074
Saving checkpoint... 
Iteration: 1398043707, states[0] = 32.873085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1408362558, states[0] = -93.800015, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1419057240, states[0] = -94.094910, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1429769466, states[0] = -94.074155, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1440264544, states[0] = -72.320962, states[40]= 0.000020
Saving checkpoint... 
Iteration: 1450514553, states[0] = -94.038015, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1460216541, states[0] = -34.486477, states[40]= 0.003905
Saving checkpoint... 
Iteration: 1469240805, states[0] = -94.087574, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1474847276, states[0] = -94.099902, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1483622252, states[0] = -94.076458, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1492598411, states[0] = -94.076179, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.945683
 - CaMKt in component CaMK (millimolar): 0.002622
 - cass in component intracellular_ions (millimolar): 0.000097
 - nai in component intracellular_ions (millimolar): 7.857748
 - nass in component intracellular_ions (millimolar): 7.857902
 - ki in component intracellular_ions (millimolar): 143.920952
 - kss in component intracellular_ions (millimolar): 143.920936
 - cansr in component intracellular_ions (millimolar): 1.838757
 - cajsr in component intracellular_ions (millimolar): 1.840747
 - cai in component intracellular_ions (millimolar): 0.000102
 - m in component INa (dimensionless): 0.003985
 - hf in component INa (dimensionless): 0.862393
 - hs in component INa (dimensionless): 0.862394
 - j in component INa (dimensionless): 0.862397
 - hsp in component INa (dimensionless): 0.693513
 - jp in component INa (dimensionless): 0.862399
 - mL in component INaL (dimensionless): 0.000059
 - hL in component INaL (dimensionless): 0.703262
 - hLp in component INaL (dimensionless): 0.507866
 - a in component Ito (dimensionless): 0.000665
 - iF in component Ito (dimensionless): 0.999846
 - iS in component Ito (dimensionless): 0.989955
 - ap in component Ito (dimensionless): 0.000339
 - iFp in component Ito (dimensionless): 0.999846
 - iSp in component Ito (dimensionless): 0.995844
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.994740
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004497
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.009414
 - xs1 in component IKs (dimensionless): 0.054392
 - xs2 in component IKs (dimensionless): 0.000098
 - xk1 in component IK1 (dimensionless): 0.997577
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
22:18:02 (73907): called boinc_finish(0)

</stderr_txt>
]]>


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