𝕏

Task 55711363

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pueyo_APDR-conf_435_2
Workunit 26208249
Created 2 Jul 2024, 10:15:58 UTC
Sent 2 Jul 2024, 14:21:14 UTC
Report deadline 5 Jul 2024, 23:57:14 UTC
Received 3 Jul 2024, 6:52:43 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 222118
Run time 3 hours 1 min 27 sec
CPU time 3 hours 0 min 2 sec
Validate state Valid
Credit 62.65
Device peak FLOPS 4.18 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.63 MB
Peak swap size 3.82 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pueyo_APDR-conf_435.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pueyo_APDR-conf_435_2_r1705894214_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pueyo_APDR-conf_435_2_r1705894214_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 110.720251
     * GNaL_b in INaL: 0.007103
     * Gto_b in Ito: 0.095519
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032000
     * GKs_b in IKs: 0.001979
     * GK1_b in IK1: 0.161659
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 68.045601
     * GKb_b in IKb: 0.003789
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.054378
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 9207924, states[0] = -94.800508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 21051690, states[0] = 11.025191, states[40]= 0.004774
Saving checkpoint... 
Iteration: 33021601, states[0] = 20.387437, states[40]= 0.007994
Saving checkpoint... 
Iteration: 44879288, states[0] = -94.900544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57044357, states[0] = 14.078762, states[40]= 0.004871
Saving checkpoint... 
Iteration: 69156013, states[0] = -75.602914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 81478176, states[0] = -94.910616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 93139557, states[0] = -54.542416, states[40]= 0.000014
Saving checkpoint... 
Iteration: 105077802, states[0] = 0.228755, states[40]= 0.004180
Saving checkpoint... 
Iteration: 116636147, states[0] = -50.707316, states[40]= 0.000026
Saving checkpoint... 
Iteration: 128793969, states[0] = -94.837233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 140796275, states[0] = -94.838648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 152979838, states[0] = -94.905594, states[40]= 0.000000
Saving checkpoint... 
Iteration: 164949932, states[0] = -94.900781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176591975, states[0] = -9.290238, states[40]= 0.002425
Saving checkpoint... 
Iteration: 188594458, states[0] = -11.378041, states[40]= 0.002015
Saving checkpoint... 
Iteration: 200270126, states[0] = -94.813873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212105397, states[0] = -21.197467, states[40]= 0.000899
Saving checkpoint... 
Iteration: 223979050, states[0] = -94.904830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236230237, states[0] = -94.762327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 248204486, states[0] = -94.717438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260259720, states[0] = -94.802222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 272484806, states[0] = -94.905479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284456962, states[0] = -94.901429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296214143, states[0] = -94.735256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 308456170, states[0] = -94.901274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 320381379, states[0] = -94.883037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 332406737, states[0] = -94.890713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 344555963, states[0] = 10.042680, states[40]= 0.004748
Saving checkpoint... 
Iteration: 356569079, states[0] = 4.628054, states[40]= 0.004569
Saving checkpoint... 
Iteration: 368512726, states[0] = 21.713541, states[40]= 0.028286
Saving checkpoint... 
Iteration: 380254937, states[0] = -94.796412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 392027540, states[0] = 19.379837, states[40]= 0.006094
Saving checkpoint... 
Iteration: 403952971, states[0] = -94.900660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415735504, states[0] = -94.770159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 427788144, states[0] = -94.830690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439510937, states[0] = 21.936689, states[40]= 0.042541
Saving checkpoint... 
Iteration: 451369277, states[0] = -94.878555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 463043122, states[0] = 14.683937, states[40]= 0.004897
Saving checkpoint... 
Iteration: 475081213, states[0] = -1.641364, states[40]= 0.003918
Saving checkpoint... 
Iteration: 487091908, states[0] = -9.219751, states[40]= 0.002439
Saving checkpoint... 
Iteration: 499107383, states[0] = -22.990467, states[40]= 0.000814
Saving checkpoint... 
Iteration: 511140246, states[0] = -54.998834, states[40]= 0.000013
Saving checkpoint... 
Iteration: 523080314, states[0] = -1.109027, states[40]= 0.003998
Saving checkpoint... 
Iteration: 535094115, states[0] = -11.071822, states[40]= 0.002073
Saving checkpoint... 
Iteration: 543978564, states[0] = -94.904458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 555737917, states[0] = -94.773600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567401213, states[0] = -94.889028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579402237, states[0] = -94.889307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591123935, states[0] = -38.195494, states[40]= 0.000174
Saving checkpoint... 
Iteration: 603231345, states[0] = -94.763730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615108709, states[0] = -24.190729, states[40]= 0.000762
Saving checkpoint... 
Iteration: 627377332, states[0] = -94.881408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 639428257, states[0] = -94.895702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 651345595, states[0] = -94.868180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 663201836, states[0] = -94.711985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 675189255, states[0] = -94.683168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 687038687, states[0] = 16.165511, states[40]= 0.005047
Saving checkpoint... 
Iteration: 698880375, states[0] = -94.882424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 710837023, states[0] = -94.863804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 722853583, states[0] = -94.871851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735072946, states[0] = 2.811312, states[40]= 0.004441
Saving checkpoint... 
Iteration: 747121030, states[0] = -35.456475, states[40]= 0.000254
Saving checkpoint... 
Iteration: 759058338, states[0] = 9.126434, states[40]= 0.004732
Saving checkpoint... 
Iteration: 770999253, states[0] = -94.906810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782822372, states[0] = -94.855434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795049347, states[0] = 12.492383, states[40]= 0.004796
Saving checkpoint... 
Iteration: 807081035, states[0] = -1.534743, states[40]= 0.003934
Saving checkpoint... 
Iteration: 818845622, states[0] = -94.868076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 830650151, states[0] = -66.484343, states[40]= 0.000002
Saving checkpoint... 
Iteration: 842675794, states[0] = -94.389845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854645242, states[0] = -60.586203, states[40]= 0.000005
Saving checkpoint... 
Iteration: 866524364, states[0] = 20.096927, states[40]= 0.006856
Saving checkpoint... 
Iteration: 878807483, states[0] = -94.845557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 890813435, states[0] = -94.849648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 902675614, states[0] = -94.374094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914469000, states[0] = -94.902856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926336317, states[0] = -94.863280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 935317916, states[0] = -94.852545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 947212316, states[0] = -94.731498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 959148271, states[0] = -64.154372, states[40]= 0.000003
Saving checkpoint... 
Iteration: 971188323, states[0] = -94.679702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 983081159, states[0] = -1.608818, states[40]= 0.003923
Saving checkpoint... 
Iteration: 995109528, states[0] = -24.931929, states[40]= 0.000729
Saving checkpoint... 
Iteration: 1006981253, states[0] = -94.904492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019014838, states[0] = 21.511746, states[40]= 0.018493
Saving checkpoint... 
Iteration: 1031020188, states[0] = 20.857811, states[40]= 0.009003
Saving checkpoint... 
Iteration: 1042919365, states[0] = -94.893399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1054867428, states[0] = -94.877417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1066723643, states[0] = -94.751080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1078654060, states[0] = -71.753959, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1090608213, states[0] = -23.741525, states[40]= 0.000781
Saving checkpoint... 
Iteration: 1102507453, states[0] = 23.220628, states[40]= 0.098281
Saving checkpoint... 
Iteration: 1114570530, states[0] = 3.961979, states[40]= 0.004527
Saving checkpoint... 
Iteration: 1126657578, states[0] = -77.155917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136387228, states[0] = -94.884406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149446628, states[0] = -94.899016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1161361482, states[0] = -94.874949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1169671110, states[0] = -93.540535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1181814728, states[0] = -94.850304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193896528, states[0] = -94.887239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205936304, states[0] = -94.896994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1217805564, states[0] = -94.843944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1229882792, states[0] = -94.882878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1241882938, states[0] = -94.882919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253804756, states[0] = -94.843332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1265976798, states[0] = -94.903717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278056822, states[0] = 9.714049, states[40]= 0.004743
Saving checkpoint... 
Iteration: 1290117929, states[0] = -32.583962, states[40]= 0.000366
Saving checkpoint... 
Iteration: 1302010244, states[0] = 22.062630, states[40]= 0.050217
Saving checkpoint... 
Iteration: 1314055173, states[0] = 10.342959, states[40]= 0.004753
Saving checkpoint... 
Iteration: 1326065710, states[0] = 6.113862, states[40]= 0.004643
Saving checkpoint... 
Iteration: 1337984393, states[0] = -94.904665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1349739324, states[0] = -94.775070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1361713414, states[0] = -94.733190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1373483782, states[0] = -94.904563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385544615, states[0] = 14.168374, states[40]= 0.004864
Saving checkpoint... 
Iteration: 1397277251, states[0] = -94.820030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1409113544, states[0] = -28.574790, states[40]= 0.000557
Saving checkpoint... 
Iteration: 1421012297, states[0] = 21.759090, states[40]= 0.031090
Saving checkpoint... 
Iteration: 1432936443, states[0] = -94.896864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444994950, states[0] = -94.905860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457116219, states[0] = -31.014993, states[40]= 0.000437
Saving checkpoint... 
Iteration: 1469305907, states[0] = -94.844016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481354070, states[0] = -94.871539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493180384, states[0] = -94.603410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1505417717, states[0] = 21.560325, states[40]= 0.013960
Saving checkpoint... 
Iteration: 1517232195, states[0] = -71.270385, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1529273989, states[0] = -94.996368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1541331508, states[0] = -95.111811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1553263932, states[0] = -94.982161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1565046787, states[0] = -95.141564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1577211074, states[0] = -46.830520, states[40]= 0.000050
Saving checkpoint... 
Iteration: 1589342481, states[0] = -95.141955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1601213636, states[0] = -50.075634, states[40]= 0.000031
Saving checkpoint... 
Iteration: 1613261338, states[0] = -94.983177, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1625392465, states[0] = -95.189671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1637227584, states[0] = -68.074233, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1649178733, states[0] = -12.543679, states[40]= 0.002066
Saving checkpoint... 
Iteration: 1661193494, states[0] = -28.036846, states[40]= 0.000568
Saving checkpoint... 
Iteration: 1673231386, states[0] = -73.989565, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1685236689, states[0] = -83.377120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1697098129, states[0] = -95.194484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1708934939, states[0] = -80.205327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1720923095, states[0] = -61.997478, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1732703461, states[0] = -95.088948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1744639268, states[0] = -87.742307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1756604168, states[0] = -39.382699, states[40]= 0.000149
Saving checkpoint... 
Iteration: 1768492855, states[0] = -95.191102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1780431795, states[0] = -95.132876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1792152013, states[0] = -95.156664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1804150563, states[0] = -73.096955, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1816009736, states[0] = 21.935593, states[40]= 0.056783
Saving checkpoint... 
Iteration: 1827787039, states[0] = -94.861026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1839508836, states[0] = 22.339393, states[40]= 0.070817
Saving checkpoint... 
Iteration: 1851262703, states[0] = -94.820724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1863143764, states[0] = -59.751067, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1874926785, states[0] = -94.902338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1886845261, states[0] = -94.872618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1898692994, states[0] = -94.696504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1910786015, states[0] = -94.830442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1922747669, states[0] = -94.787967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1934640434, states[0] = -55.298698, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1946544100, states[0] = 14.333814, states[40]= 0.004874
Saving checkpoint... 
Iteration: 1958698007, states[0] = -94.704035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1970642831, states[0] = -57.888883, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1982736001, states[0] = -94.770050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1994431333, states[0] = -94.895573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2005900572, states[0] = -94.887934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2017728778, states[0] = -94.758772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2029537113, states[0] = 16.668908, states[40]= 0.005124
Saving checkpoint... 
Iteration: 2041452910, states[0] = -94.899496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2053474203, states[0] = -94.902781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2065580736, states[0] = -1.357428, states[40]= 0.003961
Saving checkpoint... 
Iteration: 2077405752, states[0] = -94.889181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2089334892, states[0] = -94.861653, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.781785
 - CaMKt in component CaMK (millimolar): 0.007188
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.732830
 - nass in component intracellular_ions (millimolar): 6.732889
 - ki in component intracellular_ions (millimolar): 145.243058
 - kss in component intracellular_ions (millimolar): 145.243039
 - cansr in component intracellular_ions (millimolar): 1.317155
 - cajsr in component intracellular_ions (millimolar): 1.278507
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003663
 - hf in component INa (dimensionless): 0.877902
 - hs in component INa (dimensionless): 0.877897
 - j in component INa (dimensionless): 0.877870
 - hsp in component INa (dimensionless): 0.721888
 - jp in component INa (dimensionless): 0.877851
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.705680
 - hLp in component INaL (dimensionless): 0.445276
 - a in component Ito (dimensionless): 0.000629
 - iF in component Ito (dimensionless): 0.999867
 - iS in component Ito (dimensionless): 0.615737
 - ap in component Ito (dimensionless): 0.000320
 - iFp in component Ito (dimensionless): 0.999867
 - iSp in component Ito (dimensionless): 0.689579
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.933260
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999877
 - jca in component ICaL (dimensionless): 0.999976
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001608
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.334386
 - xs1 in component IKs (dimensionless): 0.248395
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997369
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
01:52:20 (133152): called boinc_finish(0)

</stderr_txt>
]]>


CoMBA Research Group Logo
University San Jorge Logo

©2024 Universidad San Jorge