𝕏

Task 55711361

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pueyo_APDR-conf_335_2
Workunit 26208247
Created 2 Jul 2024, 10:15:58 UTC
Sent 2 Jul 2024, 14:21:14 UTC
Report deadline 5 Jul 2024, 23:57:14 UTC
Received 3 Jul 2024, 9:51:50 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 222118
Run time 3 hours 1 min 26 sec
CPU time 3 hours 0 min 7 sec
Validate state Valid
Credit 62.45
Device peak FLOPS 4.18 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.75 MB
Peak swap size 3.82 MB
Peak disk usage 0.30 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pueyo_APDR-conf_335.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pueyo_APDR-conf_335_2_r284696138_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pueyo_APDR-conf_335_2_r284696138_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 101.751602
     * GNaL_b in INaL: 0.007493
     * Gto_b in Ito: 0.082790
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032816
     * GKs_b in IKs: 0.001821
     * GK1_b in IK1: 0.161929
     * Gncx_b in INaCa_i: 0.000972
     * Pnak_b in INaK: 69.930717
     * GKb_b in IKb: 0.003717
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031789
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 9149544, states[0] = -74.736812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 20758555, states[0] = -94.899574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 32913701, states[0] = -94.974100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 44932870, states[0] = -94.967342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 56997862, states[0] = -94.970554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69181247, states[0] = -94.697171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 81175034, states[0] = -94.522202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 92920023, states[0] = -94.945791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 104538873, states[0] = 16.721513, states[40]= 0.005277
Saving checkpoint... 
Iteration: 116195670, states[0] = -94.742213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127795452, states[0] = -94.882319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 139575471, states[0] = 1.725656, states[40]= 0.004432
Saving checkpoint... 
Iteration: 148081555, states[0] = -1.703604, states[40]= 0.003979
Saving checkpoint... 
Iteration: 161152355, states[0] = -71.111091, states[40]= 0.000001
Saving checkpoint... 
Iteration: 172916186, states[0] = -94.939693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 184658580, states[0] = -81.083359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 196552728, states[0] = 11.712266, states[40]= 0.004939
Saving checkpoint... 
Iteration: 208587239, states[0] = -5.470191, states[40]= 0.003275
Saving checkpoint... 
Iteration: 220693558, states[0] = -94.734865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 232662714, states[0] = -87.810735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244588254, states[0] = -6.215940, states[40]= 0.003118
Saving checkpoint... 
Iteration: 256685377, states[0] = -94.710059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 268782544, states[0] = -94.868789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280948971, states[0] = -94.946438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 293019978, states[0] = 21.993777, states[40]= 0.009666
Saving checkpoint... 
Iteration: 305206237, states[0] = -94.760584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 317018242, states[0] = 22.301022, states[40]= 0.011537
Saving checkpoint... 
Iteration: 328704833, states[0] = -94.757830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 340413157, states[0] = -94.938282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 352469219, states[0] = -94.949879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 364510085, states[0] = 23.704514, states[40]= 0.051176
Saving checkpoint... 
Iteration: 376433868, states[0] = -94.943271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 388347751, states[0] = -94.914114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 400385741, states[0] = -94.929906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 412290730, states[0] = -94.876126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424201100, states[0] = -94.750376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 436261240, states[0] = -94.846053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448309941, states[0] = -94.891361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 460309630, states[0] = -94.891129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472500519, states[0] = -15.624314, states[40]= 0.000038
Saving checkpoint... 
Iteration: 484682618, states[0] = -94.692283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 496677364, states[0] = -94.595694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 508804257, states[0] = -94.887111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 520538172, states[0] = 17.013987, states[40]= 0.005313
Saving checkpoint... 
Iteration: 532265663, states[0] = -94.851096, states[40]= 0.000000
Saving checkpoint... 
Iteration: 543833695, states[0] = -94.906538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 552439649, states[0] = -94.944392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 564786107, states[0] = -94.871893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 577082947, states[0] = -2.537900, states[40]= 0.003839
Saving checkpoint... 
Iteration: 589204757, states[0] = -94.757509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 601219021, states[0] = -94.784111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 613032529, states[0] = 18.839992, states[40]= 0.005741
Saving checkpoint... 
Iteration: 625051862, states[0] = 12.048233, states[40]= 0.004948
Saving checkpoint... 
Iteration: 637053902, states[0] = 11.263725, states[40]= 0.004927
Saving checkpoint... 
Iteration: 649042778, states[0] = 15.409376, states[40]= 0.005119
Saving checkpoint... 
Iteration: 660949294, states[0] = -94.946238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673144075, states[0] = -60.366652, states[40]= 0.000005
Saving checkpoint... 
Iteration: 685386779, states[0] = -94.930081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 697209017, states[0] = -94.765664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709421836, states[0] = -94.940265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721345716, states[0] = -94.912882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 733475568, states[0] = -94.950602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 745523832, states[0] = 21.192633, states[40]= 0.007455
Saving checkpoint... 
Iteration: 757750188, states[0] = -94.832040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 769649875, states[0] = -67.596062, states[40]= 0.000001
Saving checkpoint... 
Iteration: 781648981, states[0] = -66.418538, states[40]= 0.000002
Saving checkpoint... 
Iteration: 793690860, states[0] = -94.727995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 805706970, states[0] = -94.761671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 817710789, states[0] = -94.768941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829914279, states[0] = -94.938265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 841853526, states[0] = -94.916613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853788176, states[0] = -94.873584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 865785495, states[0] = -94.871139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 877936068, states[0] = -94.943429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 890022041, states[0] = 21.585608, states[40]= 0.008255
Saving checkpoint... 
Iteration: 902000700, states[0] = 41.692479, states[40]= 0.006929
Saving checkpoint... 
Iteration: 913916111, states[0] = -94.938690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 925612222, states[0] = -27.520081, states[40]= 0.000611
Saving checkpoint... 
Iteration: 937390864, states[0] = -94.931290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 949131102, states[0] = -45.876373, states[40]= 0.000056
Saving checkpoint... 
Iteration: 960775762, states[0] = -94.861650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 972443205, states[0] = -94.944851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 984132482, states[0] = -47.348433, states[40]= 0.000045
Saving checkpoint... 
Iteration: 995903869, states[0] = -94.935276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1007995666, states[0] = -94.953128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020145235, states[0] = -61.748134, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1032161252, states[0] = -85.568162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044089308, states[0] = -7.016461, states[40]= 0.002947
Saving checkpoint... 
Iteration: 1056020031, states[0] = 21.984145, states[40]= 0.009621
Saving checkpoint... 
Iteration: 1067955908, states[0] = -94.947195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1080080818, states[0] = -1.222771, states[40]= 0.004053
Saving checkpoint... 
Iteration: 1091689033, states[0] = -94.722872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103511075, states[0] = 23.451216, states[40]= 0.040734
Saving checkpoint... 
Iteration: 1115454134, states[0] = -94.946846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1123677661, states[0] = -94.605275, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136650934, states[0] = -69.030857, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1148735165, states[0] = -94.810398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1160726554, states[0] = -94.796662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1172714504, states[0] = -94.775613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1184635712, states[0] = -50.865057, states[40]= 0.000026
Saving checkpoint... 
Iteration: 1196869112, states[0] = -94.923183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1208926880, states[0] = -94.941157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1221182812, states[0] = -94.693415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1233330575, states[0] = -94.904296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245463942, states[0] = -94.948461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1257393711, states[0] = -94.932010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1269132744, states[0] = -47.629963, states[40]= 0.000043
Saving checkpoint... 
Iteration: 1280884273, states[0] = -94.928836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1292621115, states[0] = -35.855163, states[40]= 0.000242
Saving checkpoint... 
Iteration: 1304658733, states[0] = -81.300605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1316391694, states[0] = -94.931321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328175269, states[0] = -94.493152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1339930314, states[0] = -94.941865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1351776139, states[0] = -94.861783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1363698275, states[0] = -94.744047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1375756999, states[0] = -94.840337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387868562, states[0] = -94.922839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1400159190, states[0] = -82.090822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412001830, states[0] = 45.772880, states[40]= 0.081729
Saving checkpoint... 
Iteration: 1423911836, states[0] = -94.937236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1435666558, states[0] = -91.959988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447627332, states[0] = -41.965348, states[40]= 0.000102
Saving checkpoint... 
Iteration: 1456655058, states[0] = -75.136401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1468628530, states[0] = -43.189785, states[40]= 0.000085
Saving checkpoint... 
Iteration: 1480892624, states[0] = -94.931519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493078457, states[0] = 0.145992, states[40]= 0.004246
Saving checkpoint... 
Iteration: 1505117964, states[0] = 22.538155, states[40]= 0.014047
Saving checkpoint... 
Iteration: 1516923526, states[0] = -59.701885, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1528888232, states[0] = -20.651391, states[40]= 0.000997
Saving checkpoint... 
Iteration: 1540964984, states[0] = -95.016447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1552627191, states[0] = -66.897898, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1564770096, states[0] = -95.204876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1573424710, states[0] = -95.154718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1585591594, states[0] = -25.458227, states[40]= 0.000703
Saving checkpoint... 
Iteration: 1597537463, states[0] = 14.693011, states[40]= 0.006250
Saving checkpoint... 
Iteration: 1609459840, states[0] = -95.202407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1621321436, states[0] = -59.996326, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1633343138, states[0] = -92.547936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1645593314, states[0] = -27.482307, states[40]= 0.000599
Saving checkpoint... 
Iteration: 1657566500, states[0] = -1.359804, states[40]= 0.004568
Saving checkpoint... 
Iteration: 1669220147, states[0] = 21.419016, states[40]= 0.010859
Saving checkpoint... 
Iteration: 1681376932, states[0] = -95.069819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1693123870, states[0] = -95.160377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1705443254, states[0] = -95.186276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1717361228, states[0] = -95.022009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1729045342, states[0] = -93.740198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1740744165, states[0] = -93.208636, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1752732003, states[0] = -75.728875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1764405541, states[0] = -40.710198, states[40]= 0.000124
Saving checkpoint... 
Iteration: 1775973123, states[0] = -95.216742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1787985022, states[0] = -95.226365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1800071274, states[0] = -2.302588, states[40]= 0.004359
Saving checkpoint... 
Iteration: 1811792965, states[0] = -94.923964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1823487831, states[0] = -94.986892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1835384840, states[0] = -94.953611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1847281915, states[0] = -94.884759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1859230027, states[0] = -94.814282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1871107304, states[0] = -23.450933, states[40]= 0.000798
Saving checkpoint... 
Iteration: 1882988381, states[0] = -94.957595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1895213692, states[0] = -94.777830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1907277329, states[0] = -94.865501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1919179705, states[0] = -94.658968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1930883299, states[0] = -94.929457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1942940751, states[0] = -94.944680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1954749954, states[0] = -94.831624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1966740506, states[0] = -94.818288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1978777172, states[0] = -94.862715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1990676522, states[0] = -94.561965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2002610545, states[0] = -25.979268, states[40]= 0.000684
Saving checkpoint... 
Iteration: 2014578611, states[0] = 0.056041, states[40]= 0.004234
Saving checkpoint... 
Iteration: 2026685590, states[0] = -94.709901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2038747558, states[0] = -94.827704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2050506352, states[0] = 26.212994, states[40]= 0.118537
Saving checkpoint... 
Iteration: 2059123040, states[0] = -37.710796, states[40]= 0.000188
Saving checkpoint... 
Iteration: 2071038135, states[0] = 17.026511, states[40]= 0.005315
Saving checkpoint... 
Iteration: 2083049227, states[0] = 13.044877, states[40]= 0.004980
Saving checkpoint... 
Iteration: 2094911259, states[0] = -94.936607, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.828778
 - CaMKt in component CaMK (millimolar): 0.007038
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.646022
 - nass in component intracellular_ions (millimolar): 6.646082
 - ki in component intracellular_ions (millimolar): 145.331347
 - kss in component intracellular_ions (millimolar): 145.331328
 - cansr in component intracellular_ions (millimolar): 1.313254
 - cajsr in component intracellular_ions (millimolar): 1.274846
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003645
 - hf in component INa (dimensionless): 0.878727
 - hs in component INa (dimensionless): 0.878722
 - j in component INa (dimensionless): 0.878693
 - hsp in component INa (dimensionless): 0.723434
 - jp in component INa (dimensionless): 0.878673
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.707173
 - hLp in component INaL (dimensionless): 0.447433
 - a in component Ito (dimensionless): 0.000627
 - iF in component Ito (dimensionless): 0.999868
 - iS in component Ito (dimensionless): 0.616788
 - ap in component Ito (dimensionless): 0.000319
 - iFp in component Ito (dimensionless): 0.999868
 - iSp in component Ito (dimensionless): 0.690482
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.931011
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999872
 - jca in component ICaL (dimensionless): 0.999976
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001608
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.338722
 - xs1 in component IKs (dimensionless): 0.249799
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997356
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
04:56:09 (134251): called boinc_finish(0)

</stderr_txt>
]]>


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