𝕏

Task 55711076

Name HuVeMOp_20240626064103635658_ORdGradInc_k_24-BASE_MID-conf_912_3
Workunit 26009067
Created 2 Jul 2024, 9:19:05 UTC
Sent 2 Jul 2024, 14:19:17 UTC
Report deadline 5 Jul 2024, 14:19:17 UTC
Received 2 Jul 2024, 23:07:35 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 228779
Run time 1 hours 43 min 16 sec
CPU time 1 hours 36 min 40 sec
Validate state Invalid
Credit 0.00
Device peak FLOPS 4.70 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.89 MB
Peak swap size 4.13 GB
Peak disk usage 0.33 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626064103635658_ORdGradInc_k_24-BASE_MID-conf_912.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626064103635658_ORdGradInc_k_24-BASE_MID-conf_912_3_r540778084_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240626064103635658_ORdGradInc_k_24-BASE_MID-conf_912_3_r540778084_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 96.381646
     * GNaL_b in INaL: 0.008475
     * Gto_b in Ito: 0.066039
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032376
     * GKs_b in IKs: 0.001811
     * GK1_b in IK1: 0.156250
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 65.989211
     * GKb_b in IKb: 0.003897
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.042021
     * celltype in environment: 2.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 12394709, states[0] = -86.688571, states[40]= 0.000001
Saving checkpoint... 
Iteration: 24518142, states[0] = 33.998310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 36174172, states[0] = -38.725389, states[40]= 0.000247
Saving checkpoint... 
Iteration: 48084259, states[0] = 15.132772, states[40]= 0.000003
Saving checkpoint... 
Iteration: 60327423, states[0] = -86.675535, states[40]= 0.000001
Saving checkpoint... 
Iteration: 72538562, states[0] = 31.163795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84007552, states[0] = 27.494529, states[40]= -0.000000
Saving checkpoint... 
Iteration: 95516243, states[0] = 32.812538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 106531517, states[0] = 32.421649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118113941, states[0] = -0.636337, states[40]= 0.000084
Saving checkpoint... 
Iteration: 130539751, states[0] = 30.534986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 142199012, states[0] = -79.598763, states[40]= 0.000001
Saving checkpoint... 
Iteration: 153518517, states[0] = 33.086821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 165567449, states[0] = 20.925339, states[40]= 0.000001
Saving checkpoint... 
Iteration: 176921177, states[0] = -86.850882, states[40]= 0.000002
Saving checkpoint... 
Iteration: 188225597, states[0] = -86.253204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 199407113, states[0] = -86.838385, states[40]= 0.000002
Saving checkpoint... 
Iteration: 211016345, states[0] = 32.714995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 222152922, states[0] = -30.072233, states[40]= 0.000465
Saving checkpoint... 
Iteration: 233995191, states[0] = -86.889781, states[40]= 0.000002
Saving checkpoint... 
Iteration: 245966550, states[0] = -86.877477, states[40]= 0.000002
Saving checkpoint... 
Iteration: 257357427, states[0] = -86.773837, states[40]= 0.000002
Saving checkpoint... 
Iteration: 268892862, states[0] = -86.821183, states[40]= 0.000002
Saving checkpoint... 
Iteration: 280365182, states[0] = -86.784936, states[40]= 0.000002
Saving checkpoint... 
Iteration: 292277309, states[0] = -86.553180, states[40]= 0.000001
Saving checkpoint... 
Iteration: 304669478, states[0] = -44.324868, states[40]= 0.000172
Saving checkpoint... 
Iteration: 316872807, states[0] = -86.794115, states[40]= 0.000002
Saving checkpoint... 
Iteration: 328739446, states[0] = -86.347438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 340769666, states[0] = -86.516593, states[40]= 0.000001
Saving checkpoint... 
Iteration: 351931935, states[0] = -86.851906, states[40]= 0.000002
Saving checkpoint... 
Iteration: 364363981, states[0] = -86.778924, states[40]= 0.000002
Saving checkpoint... 
Iteration: 376536113, states[0] = 31.356776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 387694334, states[0] = -73.428877, states[40]= 0.000004
Saving checkpoint... 
Iteration: 399353990, states[0] = -86.761005, states[40]= 0.000002
Saving checkpoint... 
Iteration: 411000662, states[0] = 32.804770, states[40]= 0.351603
Saving checkpoint... 
Iteration: 422623958, states[0] = -7.687094, states[40]= 0.000139
Saving checkpoint... 
Iteration: 434802799, states[0] = -86.639298, states[40]= 0.000001
Saving checkpoint... 
Iteration: 447118971, states[0] = -4.165027, states[40]= 0.000118
Saving checkpoint... 
Iteration: 458002998, states[0] = 21.116749, states[40]= 1.210481
Saving checkpoint... 
Iteration: 470017655, states[0] = 32.953687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 481924784, states[0] = -86.840036, states[40]= 0.000002
Saving checkpoint... 
Iteration: 493779308, states[0] = -86.551247, states[40]= 0.000001
Saving checkpoint... 
Iteration: 505165086, states[0] = -40.262956, states[40]= 0.000256
Saving checkpoint... 
Iteration: 517012486, states[0] = 31.407555, states[40]= -0.000000
Saving checkpoint... 
Iteration: 528672408, states[0] = -47.127612, states[40]= 0.000127
Saving checkpoint... 
Iteration: 540423795, states[0] = -86.836317, states[40]= 0.000002
Saving checkpoint... 
Iteration: 552437813, states[0] = -86.845826, states[40]= 0.000002
Saving checkpoint... 
Iteration: 564130356, states[0] = -12.713862, states[40]= 0.000145
Saving checkpoint... 
Iteration: 576141597, states[0] = -21.620744, states[40]= 0.000262
Saving checkpoint... 
Iteration: 587363766, states[0] = -86.767256, states[40]= 0.000002
Saving checkpoint... 
Iteration: 599094125, states[0] = 9.174752, states[40]= 0.000016
Saving checkpoint... 
Iteration: 611659916, states[0] = -35.755339, states[40]= 0.000367
Saving checkpoint... 
Iteration: 623843511, states[0] = -86.730526, states[40]= 0.000002
Saving checkpoint... 
Iteration: 634953200, states[0] = -86.851091, states[40]= 0.000002
Saving checkpoint... 
Iteration: 646880917, states[0] = -86.788068, states[40]= 0.000002
Saving checkpoint... 
Iteration: 659214098, states[0] = -86.072500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671060702, states[0] = 23.550916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683718807, states[0] = -86.162370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696027307, states[0] = 32.917407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 707966806, states[0] = -86.854477, states[40]= 0.000002
Saving checkpoint... 
Iteration: 720184762, states[0] = -60.215252, states[40]= 0.000024
Saving checkpoint... 
Iteration: 732279988, states[0] = -86.541785, states[40]= 0.000001
Saving checkpoint... 
Iteration: 744360689, states[0] = -86.754496, states[40]= 0.000002
Saving checkpoint... 
Iteration: 756980825, states[0] = -86.858264, states[40]= 0.000002
Saving checkpoint... 
Iteration: 769059545, states[0] = 23.992036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780391330, states[0] = -86.793658, states[40]= 0.000002
Saving checkpoint... 
Iteration: 792848153, states[0] = -86.730650, states[40]= 0.000002
Saving checkpoint... 
Iteration: 804001744, states[0] = 31.192628, states[40]= 1.872014
Saving checkpoint... 
Iteration: 815835346, states[0] = -86.704201, states[40]= 0.000002
Saving checkpoint... 
Iteration: 826836610, states[0] = -86.706316, states[40]= 0.000002
Saving checkpoint... 
Iteration: 839428618, states[0] = -86.824849, states[40]= 0.000002
Saving checkpoint... 
Iteration: 851994375, states[0] = -86.858628, states[40]= 0.000002
Saving checkpoint... 
Iteration: 864235533, states[0] = -86.292880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 876689119, states[0] = -65.689691, states[40]= 0.000011
Saving checkpoint... 
Iteration: 889517375, states[0] = 32.917897, states[40]= -0.000000
Saving checkpoint... 
Iteration: 902501305, states[0] = 34.700086, states[40]= 2.070749
Saving checkpoint... 
Iteration: 914584069, states[0] = 13.799247, states[40]= 0.000005
Saving checkpoint... 
Iteration: 927354529, states[0] = -86.735082, states[40]= 0.000002
Saving checkpoint... 
Iteration: 940158110, states[0] = -34.221135, states[40]= 0.000401
Saving checkpoint... 
Iteration: 952676651, states[0] = -51.331980, states[40]= 0.000077
Saving checkpoint... 
Iteration: 964848229, states[0] = -86.722041, states[40]= 0.000002
Saving checkpoint... 
Iteration: 977082511, states[0] = 14.496182, states[40]= 0.000004
Saving checkpoint... 
Iteration: 989781626, states[0] = -86.535206, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1003245099, states[0] = -86.348710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1015557535, states[0] = 24.747334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1028772790, states[0] = -86.495411, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1041236365, states[0] = -86.289391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1054022975, states[0] = 33.244906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1066112833, states[0] = -0.352814, states[40]= 0.000082
Saving checkpoint... 
Iteration: 1078935313, states[0] = -86.817506, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1091669801, states[0] = -44.562022, states[40]= 0.000167
Saving checkpoint... 
Iteration: 1105379210, states[0] = -86.762641, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1118204486, states[0] = -84.600748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1131119981, states[0] = -4.804807, states[40]= 0.000122
Saving checkpoint... 
Iteration: 1143998024, states[0] = -86.845160, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1156243260, states[0] = -86.329117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1169563529, states[0] = 22.466872, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1182285846, states[0] = -86.541973, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1195670676, states[0] = -45.386559, states[40]= 0.000152
Saving checkpoint... 
Iteration: 1208458839, states[0] = -86.825206, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1221828875, states[0] = -86.669208, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1234806464, states[0] = -86.609555, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1246785111, states[0] = -86.535820, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1260484938, states[0] = -86.834513, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1273257938, states[0] = -86.409364, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1286377306, states[0] = -86.750984, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1298824187, states[0] = -86.654212, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1311609717, states[0] = 1.397293, states[40]= 0.000065
Saving checkpoint... 
Iteration: 1325030527, states[0] = 32.479117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1337395526, states[0] = -86.770043, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1350530358, states[0] = 32.507085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1363921985, states[0] = -86.793232, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1376974843, states[0] = -86.824431, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1389337108, states[0] = -86.678709, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1402536007, states[0] = 31.401616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415368768, states[0] = -86.732667, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1428159134, states[0] = -35.034232, states[40]= 0.000380
Saving checkpoint... 
Iteration: 1440783423, states[0] = -86.519220, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1453593661, states[0] = 9.415487, states[40]= 0.000015
Saving checkpoint... 
Iteration: 1466370718, states[0] = -86.732861, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1479444833, states[0] = -86.803510, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1492528662, states[0] = 32.762923, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.703762
 - CaMKt in component CaMK (millimolar): 0.024259
 - cass in component intracellular_ions (millimolar): 0.000091
 - nai in component intracellular_ions (millimolar): 8.131688
 - nass in component intracellular_ions (millimolar): 8.131833
 - ki in component intracellular_ions (millimolar): 143.317061
 - kss in component intracellular_ions (millimolar): 143.317026
 - cansr in component intracellular_ions (millimolar): 1.984814
 - cajsr in component intracellular_ions (millimolar): 1.914741
 - cai in component intracellular_ions (millimolar): 0.000094
 - m in component INa (dimensionless): 0.008264
 - hf in component INa (dimensionless): 0.655972
 - hs in component INa (dimensionless): 0.655940
 - j in component INa (dimensionless): 0.655757
 - hsp in component INa (dimensionless): 0.407624
 - jp in component INa (dimensionless): 0.655627
 - mL in component INaL (dimensionless): 0.000235
 - hL in component INaL (dimensionless): 0.451307
 - hLp in component INaL (dimensionless): 0.217424
 - a in component Ito (dimensionless): 0.001084
 - iF in component Ito (dimensionless): 0.999452
 - iS in component Ito (dimensionless): 0.527474
 - ap in component Ito (dimensionless): 0.000552
 - iFp in component Ito (dimensionless): 0.999452
 - iSp in component Ito (dimensionless): 0.569961
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.872586
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999564
 - jca in component ICaL (dimensionless): 0.999934
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003596
 - xrf in component IKr (dimensionless): 0.000011
 - xrs in component IKr (dimensionless): 0.517937
 - xs1 in component IKs (dimensionless): 0.339854
 - xs2 in component IKs (dimensionless): 0.000220
 - xk1 in component IK1 (dimensionless): 0.997054
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000002
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000002
18:22:23 (22411): called boinc_finish(0)

</stderr_txt>
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