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Task 55710855

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-Coppini_2000-conf_91_2
Workunit 26233987
Created 2 Jul 2024, 7:57:27 UTC
Sent 2 Jul 2024, 14:24:22 UTC
Report deadline 5 Jul 2024, 14:24:22 UTC
Received 4 Jul 2024, 14:12:23 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 222504
Run time 1 hours 20 min 49 sec
CPU time 59 min 45 sec
Validate state Valid
Credit 42.90
Device peak FLOPS 4.76 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 7.12 MB
Peak swap size 32.99 GB
Peak disk usage 0.63 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Coppini_2000-conf_91.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Coppini_2000-conf_91_2_r1455851042_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Coppini_2000-conf_91_2_r1455851042_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.590086
     * GNaL_b in INaL: 0.005115
     * Gto_b in Ito: 0.070625
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032270
     * GKs_b in IKs: 0.001860
     * GK1_b in IK1: 0.175863
     * Gncx_b in INaCa_i: 0.000954
     * Pnak_b in INaK: 67.994201
     * GKb_b in IKb: 0.003778
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.028673
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 23882748, states[0] = -94.865876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47345819, states[0] = -94.723805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 72325055, states[0] = -94.686364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95666576, states[0] = -94.811494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117167877, states[0] = -70.587302, states[40]= 0.000003
Saving checkpoint... 
Iteration: 137894718, states[0] = -94.808048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 160671108, states[0] = -94.806613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183376328, states[0] = -94.727503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204991103, states[0] = -94.804225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 227426201, states[0] = -94.758377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 250346578, states[0] = -94.699769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275863767, states[0] = -94.806352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 297867158, states[0] = -94.806237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 319408692, states[0] = -94.748639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 342632704, states[0] = -94.803195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367003416, states[0] = 37.156286, states[40]= 0.383118
Saving checkpoint... 
Iteration: 389182787, states[0] = -91.723668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 412454686, states[0] = -94.770249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 433249947, states[0] = -94.528953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 452651949, states[0] = -94.804116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472681142, states[0] = -94.805322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 492708504, states[0] = -94.806043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 513730873, states[0] = -94.806387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536950586, states[0] = -94.804206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 564749450, states[0] = -94.806482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590719402, states[0] = -94.806085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 616891305, states[0] = -94.805254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641153757, states[0] = -54.336690, states[40]= 0.000047
Saving checkpoint... 
Iteration: 664656167, states[0] = -94.803965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 691819149, states[0] = -94.806134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 718364501, states[0] = -94.716099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 745542840, states[0] = -94.792616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 781544652, states[0] = -94.792855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 817434878, states[0] = -94.761290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 851811978, states[0] = -94.805922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 885136437, states[0] = -37.758333, states[40]= 0.000513
Saving checkpoint... 
Iteration: 907228452, states[0] = -94.462538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931012863, states[0] = 28.037229, states[40]= 0.019136
Saving checkpoint... 
Iteration: 953434692, states[0] = -94.760973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977612955, states[0] = -94.800657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002396785, states[0] = -94.740130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1026146881, states[0] = -47.562521, states[40]= 0.000134
Saving checkpoint... 
Iteration: 1047105976, states[0] = -10.412281, states[40]= 0.002528
Saving checkpoint... 
Iteration: 1073103586, states[0] = -8.342158, states[40]= 0.002995
Saving checkpoint... 
Iteration: 1098720704, states[0] = -94.805241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1123837507, states[0] = -94.805204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146061459, states[0] = 15.060420, states[40]= 0.003950
Saving checkpoint... 
Iteration: 1167854691, states[0] = -94.804905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1190178123, states[0] = -86.354857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1211382515, states[0] = -94.729850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1235901155, states[0] = -94.804018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1259380558, states[0] = -94.728300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284410367, states[0] = -94.747937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1309127941, states[0] = -30.132858, states[40]= 0.001088
Saving checkpoint... 
Iteration: 1333989376, states[0] = -94.801976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1357706742, states[0] = -94.804529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385513614, states[0] = -94.785888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1409443367, states[0] = -94.764006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434034912, states[0] = 24.030003, states[40]= 0.002289
Saving checkpoint... 
Iteration: 1458263718, states[0] = -94.562679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1480408415, states[0] = -94.746474, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.677385
 - CaMKt in component CaMK (millimolar): 0.004163
 - cass in component intracellular_ions (millimolar): 0.000085
 - nai in component intracellular_ions (millimolar): 6.498608
 - nass in component intracellular_ions (millimolar): 6.498694
 - ki in component intracellular_ions (millimolar): 145.413851
 - kss in component intracellular_ions (millimolar): 145.413836
 - cansr in component intracellular_ions (millimolar): 1.593475
 - cajsr in component intracellular_ions (millimolar): 1.592685
 - cai in component intracellular_ions (millimolar): 0.000088
 - m in component INa (dimensionless): 0.003701
 - hf in component INa (dimensionless): 0.876050
 - hs in component INa (dimensionless): 0.876051
 - j in component INa (dimensionless): 0.876056
 - hsp in component INa (dimensionless): 0.718461
 - jp in component INa (dimensionless): 0.876059
 - mL in component INaL (dimensionless): 0.000052
 - hL in component INaL (dimensionless): 0.723070
 - hLp in component INaL (dimensionless): 0.516655
 - a in component Ito (dimensionless): 0.000633
 - iF in component Ito (dimensionless): 0.999864
 - iS in component Ito (dimensionless): 0.894156
 - ap in component Ito (dimensionless): 0.000322
 - iFp in component Ito (dimensionless): 0.999864
 - iSp in component Ito (dimensionless): 0.933771
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.976282
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002757
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.096094
 - xs1 in component IKs (dimensionless): 0.121588
 - xs2 in component IKs (dimensionless): 0.000090
 - xk1 in component IK1 (dimensionless): 0.997395
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
21:42:34 (7621): called boinc_finish(0)

</stderr_txt>
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