𝕏

Task 55710644

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pueyo_APDR-conf_216_2
Workunit 26198177
Created 2 Jul 2024, 6:52:58 UTC
Sent 2 Jul 2024, 14:17:45 UTC
Report deadline 5 Jul 2024, 23:53:45 UTC
Received 5 Jul 2024, 3:11:48 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 226324
Run time 2 hours 33 min 18 sec
CPU time 2 hours 31 min 40 sec
Validate state Valid
Credit 54.88
Device peak FLOPS 4.68 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.40 MB
Peak swap size 3.82 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>7.18.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pueyo_APDR-conf_216.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pueyo_APDR-conf_216_2_r1909403377_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pueyo_APDR-conf_216_2_r1909403377_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 95.887459
     * GNaL_b in INaL: 0.007429
     * Gto_b in Ito: 0.087372
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.031248
     * GKs_b in IKs: 0.001906
     * GK1_b in IK1: 0.154953
     * Gncx_b in INaCa_i: 0.000979
     * Pnak_b in INaK: 70.491307
     * GKb_b in IKb: 0.003819
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036798
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 15973219, states[0] = -95.040935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 30822638, states[0] = -94.955128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47636774, states[0] = -48.491809, states[40]= 0.000039
Saving checkpoint... 
Iteration: 63329467, states[0] = -94.929355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79267152, states[0] = -94.867637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95773610, states[0] = -94.870993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111186771, states[0] = -94.674749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128068940, states[0] = 6.072764, states[40]= 0.004650
Saving checkpoint... 
Iteration: 143732452, states[0] = -94.808815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161196653, states[0] = -94.736571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 179595465, states[0] = -9.310589, states[40]= 0.002408
Saving checkpoint... 
Iteration: 197282395, states[0] = -94.874234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212696305, states[0] = -94.734770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 228179951, states[0] = -94.319571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243247783, states[0] = -94.831371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 258589905, states[0] = -5.108062, states[40]= 0.003282
Saving checkpoint... 
Iteration: 273647513, states[0] = -58.218541, states[40]= 0.000008
Saving checkpoint... 
Iteration: 289186079, states[0] = -94.653446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 304949299, states[0] = -94.957634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 320968199, states[0] = -94.961140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338520100, states[0] = 22.034482, states[40]= 0.009075
Saving checkpoint... 
Iteration: 355676604, states[0] = -93.682685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 373432163, states[0] = -94.953792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 389772405, states[0] = -94.862996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408104362, states[0] = -16.926027, states[40]= 0.001215
Saving checkpoint... 
Iteration: 424887161, states[0] = -94.940357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 441253693, states[0] = -94.839526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459466727, states[0] = -94.960787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 475036485, states[0] = 18.020943, states[40]= 0.005189
Saving checkpoint... 
Iteration: 492364514, states[0] = -94.931071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 508709999, states[0] = -94.765400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 525191167, states[0] = -94.712810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540995071, states[0] = -94.965017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556536439, states[0] = 18.035254, states[40]= 0.005192
Saving checkpoint... 
Iteration: 572285984, states[0] = -94.877281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 587877395, states[0] = -94.936506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603978454, states[0] = -94.962604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 621785649, states[0] = -94.876915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 638217473, states[0] = -94.779964, states[40]= 0.000000
Saving checkpoint... 
Iteration: 654932811, states[0] = -94.953755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674154580, states[0] = -66.422661, states[40]= 0.000002
Saving checkpoint... 
Iteration: 690550490, states[0] = 13.284606, states[40]= 0.004818
Saving checkpoint... 
Iteration: 706589185, states[0] = -4.610598, states[40]= 0.003380
Saving checkpoint... 
Iteration: 724643962, states[0] = -54.343044, states[40]= 0.000015
Saving checkpoint... 
Iteration: 740485284, states[0] = -94.963533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755906319, states[0] = -94.946537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 771067557, states[0] = 6.711368, states[40]= 0.004676
Saving checkpoint... 
Iteration: 786702388, states[0] = -94.749299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803507067, states[0] = 24.650462, states[40]= 0.102660
Saving checkpoint... 
Iteration: 821785165, states[0] = -94.876298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839254012, states[0] = -94.839694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 856282730, states[0] = -94.873816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 875279576, states[0] = -94.870525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 894483929, states[0] = -94.963232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 911585333, states[0] = -2.133332, states[40]= 0.003828
Saving checkpoint... 
Iteration: 929104000, states[0] = -16.604626, states[40]= 0.001247
Saving checkpoint... 
Iteration: 946086512, states[0] = -2.861737, states[40]= 0.003705
Saving checkpoint... 
Iteration: 961567632, states[0] = 6.679728, states[40]= 0.004675
Saving checkpoint... 
Iteration: 977377437, states[0] = -94.936260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 994180875, states[0] = -94.411285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011032439, states[0] = 19.229963, states[40]= 0.005492
Saving checkpoint... 
Iteration: 1027325943, states[0] = -94.909475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041918380, states[0] = -94.949821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058650807, states[0] = -61.924890, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1076316642, states[0] = -94.902998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095292972, states[0] = -94.883598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112557433, states[0] = 10.736724, states[40]= 0.004779
Saving checkpoint... 
Iteration: 1129151994, states[0] = -63.304059, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1143373485, states[0] = -94.934533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1159641138, states[0] = -51.323463, states[40]= 0.000024
Saving checkpoint... 
Iteration: 1176673961, states[0] = -92.584732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193832422, states[0] = -94.913513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1209617385, states[0] = -28.487298, states[40]= 0.000585
Saving checkpoint... 
Iteration: 1226067161, states[0] = 6.878217, states[40]= 0.004683
Saving checkpoint... 
Iteration: 1241461605, states[0] = -94.959354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1259217110, states[0] = -94.778848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1273640593, states[0] = -50.746349, states[40]= 0.000027
Saving checkpoint... 
Iteration: 1289737036, states[0] = -94.814057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1305632569, states[0] = -42.534014, states[40]= 0.000096
Saving checkpoint... 
Iteration: 1323253117, states[0] = -94.838134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1339092065, states[0] = -6.656526, states[40]= 0.002962
Saving checkpoint... 
Iteration: 1355245980, states[0] = -94.827882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1372549293, states[0] = 13.711883, states[40]= 0.004828
Saving checkpoint... 
Iteration: 1389149648, states[0] = -60.602171, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1406388958, states[0] = -94.940346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422867461, states[0] = -94.931762, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1438873323, states[0] = -94.934266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454538099, states[0] = 17.512679, states[40]= 0.005104
Saving checkpoint... 
Iteration: 1472624055, states[0] = -34.497796, states[40]= 0.000300
Saving checkpoint... 
Iteration: 1488295932, states[0] = -94.886018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1504223567, states[0] = 21.067057, states[40]= 0.008720
Saving checkpoint... 
Iteration: 1520628774, states[0] = -95.146059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1537991162, states[0] = -95.092111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1555293681, states[0] = -24.213011, states[40]= 0.000785
Saving checkpoint... 
Iteration: 1570260696, states[0] = 3.770305, states[40]= 0.005159
Saving checkpoint... 
Iteration: 1585724431, states[0] = -95.175249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1601540462, states[0] = -82.350627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1616984476, states[0] = -95.248286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1631796142, states[0] = -27.317842, states[40]= 0.000624
Saving checkpoint... 
Iteration: 1646106261, states[0] = 26.624948, states[40]= 0.113341
Saving checkpoint... 
Iteration: 1661289428, states[0] = -95.112128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1677561015, states[0] = -95.227930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1694687849, states[0] = -95.252639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1710032621, states[0] = 17.191989, states[40]= 0.006452
Saving checkpoint... 
Iteration: 1725829314, states[0] = -95.187862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1741315062, states[0] = -47.594230, states[40]= 0.000047
Saving checkpoint... 
Iteration: 1756101033, states[0] = -95.137817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1770658525, states[0] = 4.826165, states[40]= 0.005254
Saving checkpoint... 
Iteration: 1786233504, states[0] = 16.829994, states[40]= 0.006364
Saving checkpoint... 
Iteration: 1803183615, states[0] = -94.724562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1819891956, states[0] = -94.983444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1836261871, states[0] = -94.876125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1853685061, states[0] = -94.667431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1869810883, states[0] = -94.907927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1890384381, states[0] = -94.943566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1907897633, states[0] = -94.946077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1923016934, states[0] = 22.449526, states[40]= 0.012975
Saving checkpoint... 
Iteration: 1940344254, states[0] = -94.921073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1956401612, states[0] = -94.944939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1973449086, states[0] = -94.956836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1989045268, states[0] = 15.119734, states[40]= 0.004881
Saving checkpoint... 
Iteration: 2004549753, states[0] = 13.545593, states[40]= 0.004824
Saving checkpoint... 
Iteration: 2019698813, states[0] = -94.740176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2034424996, states[0] = -94.950906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2049775187, states[0] = -94.864970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2064307293, states[0] = -94.895185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2079817463, states[0] = -94.902866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2096607157, states[0] = -19.408948, states[40]= 0.001016
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.840420
 - CaMKt in component CaMK (millimolar): 0.007174
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.592342
 - nass in component intracellular_ions (millimolar): 6.592402
 - ki in component intracellular_ions (millimolar): 145.384614
 - kss in component intracellular_ions (millimolar): 145.384595
 - cansr in component intracellular_ions (millimolar): 1.313167
 - cajsr in component intracellular_ions (millimolar): 1.274059
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003641
 - hf in component INa (dimensionless): 0.878931
 - hs in component INa (dimensionless): 0.878926
 - j in component INa (dimensionless): 0.878894
 - hsp in component INa (dimensionless): 0.723815
 - jp in component INa (dimensionless): 0.878873
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.705909
 - hLp in component INaL (dimensionless): 0.443257
 - a in component Ito (dimensionless): 0.000626
 - iF in component Ito (dimensionless): 0.999868
 - iS in component Ito (dimensionless): 0.611210
 - ap in component Ito (dimensionless): 0.000319
 - iFp in component Ito (dimensionless): 0.999868
 - iSp in component Ito (dimensionless): 0.683935
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.927989
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999860
 - jca in component ICaL (dimensionless): 0.999973
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001595
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.340393
 - xs1 in component IKs (dimensionless): 0.257407
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997353
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
05:11:54 (46380): called boinc_finish(0)

</stderr_txt>
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