𝕏

Task 55710359

Name HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pueyo_APDR-conf_811_2
Workunit 26354667
Created 2 Jul 2024, 5:54:25 UTC
Sent 2 Jul 2024, 14:14:38 UTC
Report deadline 5 Jul 2024, 23:50:38 UTC
Received 2 Jul 2024, 20:21:01 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236853
Run time 2 hours 54 min 19 sec
CPU time 2 hours 54 min 14 sec
Validate state Valid
Credit 62.01
Device peak FLOPS 3.54 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 4.02 MB
Peak swap size 2.31 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pueyo_APDR-conf_811.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pueyo_APDR-conf_811_2_r105844006_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701164234318976_ORdGradInc_k_26-Pueyo_APDR-conf_811_2_r105844006_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 103.056537
     * GNaL_b in INaL: 0.005599
     * Gto_b in Ito: 0.087362
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031550
     * GKs_b in IKs: 0.001979
     * GK1_b in IK1: 0.163039
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 69.243200
     * GKb_b in IKb: 0.003780
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029223
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13404937, states[0] = -95.073224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26579116, states[0] = -3.442808, states[40]= 0.003710
Saving checkpoint... 
Iteration: 39755891, states[0] = -94.931786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 52935809, states[0] = -95.025399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 66127084, states[0] = -46.006093, states[40]= 0.000053
Saving checkpoint... 
Iteration: 79403521, states[0] = -95.006185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 92578433, states[0] = -1.733052, states[40]= 0.003990
Saving checkpoint... 
Iteration: 105752642, states[0] = -94.900881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118928234, states[0] = -95.006413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132325180, states[0] = -94.964783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145515381, states[0] = 21.760456, states[40]= 0.016952
Saving checkpoint... 
Iteration: 158688946, states[0] = -94.784274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 171866413, states[0] = -94.984554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 185040320, states[0] = 15.182586, states[40]= 0.005149
Saving checkpoint... 
Iteration: 198216866, states[0] = -94.841343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 211413131, states[0] = -94.999902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 219950242, states[0] = -95.008315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 232920219, states[0] = -95.001648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 246094650, states[0] = -14.165581, states[40]= 0.001584
Saving checkpoint... 
Iteration: 259265827, states[0] = -94.912490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 272437078, states[0] = -95.005490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 285625029, states[0] = -42.993386, states[40]= 0.000085
Saving checkpoint... 
Iteration: 298851986, states[0] = -94.977418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 312023555, states[0] = 20.257212, states[40]= 0.007374
Saving checkpoint... 
Iteration: 325200189, states[0] = -94.808349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338595239, states[0] = -14.704832, states[40]= 0.001505
Saving checkpoint... 
Iteration: 351772290, states[0] = -94.919440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 364982143, states[0] = -95.013337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 378157472, states[0] = -83.539849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 391335026, states[0] = -94.968511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 404512451, states[0] = 22.211698, states[40]= 0.029974
Saving checkpoint... 
Iteration: 417687935, states[0] = -94.780519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430864386, states[0] = -94.982918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 444064086, states[0] = 5.833741, states[40]= 0.004737
Saving checkpoint... 
Iteration: 449392378, states[0] = -94.993379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462478784, states[0] = -95.012785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 475824448, states[0] = -94.962163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 488981588, states[0] = -95.013171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502177408, states[0] = -94.713000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 515374365, states[0] = -94.986914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528527454, states[0] = 19.279914, states[40]= 0.006331
Saving checkpoint... 
Iteration: 541580644, states[0] = -2.925788, states[40]= 0.003783
Saving checkpoint... 
Iteration: 554634232, states[0] = -52.603448, states[40]= 0.000018
Saving checkpoint... 
Iteration: 567797849, states[0] = -94.943059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 580971562, states[0] = -95.011612, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594135391, states[0] = -53.852910, states[40]= 0.000015
Saving checkpoint... 
Iteration: 607335706, states[0] = -94.968745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620538580, states[0] = 15.798741, states[40]= 0.005225
Saving checkpoint... 
Iteration: 633740193, states[0] = -94.879114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646942371, states[0] = -95.006317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660145809, states[0] = -65.775774, states[40]= 0.000002
Saving checkpoint... 
Iteration: 673371670, states[0] = -94.985749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686525462, states[0] = 19.798763, states[40]= 0.006774
Saving checkpoint... 
Iteration: 699679271, states[0] = -94.737359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 712833195, states[0] = -94.967248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 726184707, states[0] = -94.770292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 739346205, states[0] = -94.974254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 752507240, states[0] = 24.233002, states[40]= 0.101119
Saving checkpoint... 
Iteration: 765657523, states[0] = -83.625785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 778808865, states[0] = -94.951415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791975510, states[0] = -95.012075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 805089098, states[0] = -9.243486, states[40]= 0.002486
Saving checkpoint... 
Iteration: 818201649, states[0] = -94.811026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 831313729, states[0] = -94.954845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 844617483, states[0] = -35.594641, states[40]= 0.000244
Saving checkpoint... 
Iteration: 857790027, states[0] = -94.936229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 870971043, states[0] = -95.011334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 884204735, states[0] = -94.817265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 897420897, states[0] = -95.001265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 910611611, states[0] = -30.028755, states[40]= 0.000473
Saving checkpoint... 
Iteration: 923803918, states[0] = -94.947615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 936994253, states[0] = -95.014565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 950186332, states[0] = -94.775552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 963566968, states[0] = 4.521489, states[40]= 0.004664
Saving checkpoint... 
Iteration: 976758842, states[0] = -94.903780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 989951832, states[0] = -95.007944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1003141856, states[0] = -61.037145, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1016333113, states[0] = -94.966994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1029525163, states[0] = 19.873279, states[40]= 0.006854
Saving checkpoint... 
Iteration: 1042716871, states[0] = -94.840486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1055909511, states[0] = -94.998145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1069101304, states[0] = -20.369495, states[40]= 0.000947
Saving checkpoint... 
Iteration: 1082483385, states[0] = -95.013021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1084705056, states[0] = -94.817773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1097735549, states[0] = -94.871832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110924558, states[0] = -95.002022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1111110017, states[0] = -28.530028, states[40]= 0.000546
Saving checkpoint... 
Iteration: 1124256797, states[0] = -94.901174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137452938, states[0] = -95.008051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1150648669, states[0] = -69.517005, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1163846352, states[0] = -94.974039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1177046120, states[0] = 13.074914, states[40]= 0.004984
Saving checkpoint... 
Iteration: 1190245240, states[0] = -94.885944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1203446228, states[0] = -95.006717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1216835673, states[0] = -94.968311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230038221, states[0] = 15.923055, states[40]= 0.005243
Saving checkpoint... 
Iteration: 1243223079, states[0] = -94.851392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1256393014, states[0] = -94.993037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1269538491, states[0] = 15.829723, states[40]= 0.005230
Saving checkpoint... 
Iteration: 1282685454, states[0] = -94.772516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1295830803, states[0] = -94.965460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1308977492, states[0] = -95.012019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1322124737, states[0] = -42.696924, states[40]= 0.000088
Saving checkpoint... 
Iteration: 1335271650, states[0] = -94.918086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1348629578, states[0] = -47.667092, states[40]= 0.000041
Saving checkpoint... 
Iteration: 1361775211, states[0] = -94.921786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1374926233, states[0] = -95.002245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1388089693, states[0] = -9.747114, states[40]= 0.002381
Saving checkpoint... 
Iteration: 1401295505, states[0] = -94.940557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1414457833, states[0] = -95.008754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1418154776, states[0] = -78.894236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431307367, states[0] = -94.949868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444508422, states[0] = 23.391282, states[40]= 0.076846
Saving checkpoint... 
Iteration: 1457690032, states[0] = -94.785169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470877745, states[0] = -94.987552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1484271369, states[0] = -94.917685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497432833, states[0] = -95.003690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1510577529, states[0] = -10.822861, states[40]= 0.002410
Saving checkpoint... 
Iteration: 1523698086, states[0] = -95.258861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1536835279, states[0] = -95.210687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1549962353, states[0] = -95.070370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1563097448, states[0] = -34.370678, states[40]= 0.000284
Saving checkpoint... 
Iteration: 1576215913, states[0] = 21.834623, states[40]= 0.017168
Saving checkpoint... 
Iteration: 1589332971, states[0] = -95.226632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1602454484, states[0] = -95.031270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1615774830, states[0] = -95.274012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1628868658, states[0] = -95.104611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1642020260, states[0] = -61.800934, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1655104014, states[0] = 32.429428, states[40]= 0.136215
Saving checkpoint... 
Iteration: 1668195787, states[0] = -95.168941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1681345236, states[0] = -94.428579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1694485995, states[0] = -22.485932, states[40]= 0.000864
Saving checkpoint... 
Iteration: 1707563335, states[0] = -95.265330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1720721513, states[0] = -95.214476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1734069153, states[0] = -5.160993, states[40]= 0.003787
Saving checkpoint... 
Iteration: 1747185291, states[0] = -95.284083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1760306618, states[0] = -95.189835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1773492031, states[0] = -95.161433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1786630824, states[0] = -77.834631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1799770515, states[0] = -6.361730, states[40]= 0.003506
Saving checkpoint... 
Iteration: 1812900537, states[0] = -95.041065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1826020173, states[0] = 20.675752, states[40]= 0.009096
Saving checkpoint... 
Iteration: 1839122548, states[0] = -41.978699, states[40]= 0.000099
Saving checkpoint... 
Iteration: 1852229331, states[0] = -94.877026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1865363189, states[0] = -94.991742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1878509877, states[0] = 22.741835, states[40]= 0.054197
Saving checkpoint... 
Iteration: 1891666610, states[0] = -93.576911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1904788117, states[0] = -94.937037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1917917199, states[0] = -95.001776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1931040225, states[0] = 15.200844, states[40]= 0.005153
Saving checkpoint... 
Iteration: 1944165781, states[0] = -93.122677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1957291365, states[0] = -94.937295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1970640214, states[0] = -59.202312, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1983781595, states[0] = -94.927963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1996905855, states[0] = -94.996626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2010047626, states[0] = 12.508245, states[40]= 0.004958
Saving checkpoint... 
Iteration: 2023168109, states[0] = -93.912386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2036288151, states[0] = -94.933763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2049420096, states[0] = -95.000265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2062556805, states[0] = 8.924344, states[40]= 0.004850
Saving checkpoint... 
Iteration: 2075675314, states[0] = -94.664475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2088989991, states[0] = -95.013186, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.890305
 - CaMKt in component CaMK (millimolar): 0.007109
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.614123
 - nass in component intracellular_ions (millimolar): 6.614183
 - ki in component intracellular_ions (millimolar): 145.361248
 - kss in component intracellular_ions (millimolar): 145.361229
 - cansr in component intracellular_ions (millimolar): 1.320128
 - cajsr in component intracellular_ions (millimolar): 1.281960
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003623
 - hf in component INa (dimensionless): 0.879800
 - hs in component INa (dimensionless): 0.879796
 - j in component INa (dimensionless): 0.879766
 - hsp in component INa (dimensionless): 0.725452
 - jp in component INa (dimensionless): 0.879746
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709365
 - hLp in component INaL (dimensionless): 0.450925
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.620367
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.695165
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935499
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999886
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001632
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.329278
 - xs1 in component IKs (dimensionless): 0.241874
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997340
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
15:20:40 (3616): called boinc_finish(0)

</stderr_txt>
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