𝕏

Task 55709142

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pieske_1000-conf_836_2
Workunit 26208743
Created 2 Jul 2024, 0:49:27 UTC
Sent 2 Jul 2024, 14:19:17 UTC
Report deadline 5 Jul 2024, 14:19:17 UTC
Received 3 Jul 2024, 0:14:52 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 228779
Run time 1 hours 40 min 44 sec
CPU time 1 hours 33 min 38 sec
Validate state Valid
Credit 43.35
Device peak FLOPS 4.70 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.91 MB
Peak swap size 4.13 GB
Peak disk usage 0.33 MB

Stderr output

<core_client_version>7.16.21</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pieske_1000-conf_836.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pieske_1000-conf_836_2_r278358326_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pieske_1000-conf_836_2_r278358326_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 91.721876
     * GNaL_b in INaL: 0.006787
     * Gto_b in Ito: 0.086845
     * PCa_b in ICaL: 0.000081
     * GKr_b in IKr: 0.031992
     * GKs_b in IKs: 0.001759
     * GK1_b in IK1: 0.155500
     * Gncx_b in INaCa_i: 0.000972
     * Pnak_b in INaK: 74.649700
     * GKb_b in IKb: 0.003763
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.038543
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 12324359, states[0] = -87.038846, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23918825, states[0] = -87.012146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 36057712, states[0] = 8.870021, states[40]= 0.004577
Saving checkpoint... 
Iteration: 48398082, states[0] = -86.934910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 60037202, states[0] = 17.336767, states[40]= 0.004698
Saving checkpoint... 
Iteration: 71835183, states[0] = -86.875616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 83101200, states[0] = -19.214932, states[40]= 0.000969
Saving checkpoint... 
Iteration: 94006079, states[0] = 24.391715, states[40]= 0.116918
Saving checkpoint... 
Iteration: 105497158, states[0] = -86.909283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117207266, states[0] = -86.693882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128998387, states[0] = -86.904327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 140809890, states[0] = -86.832957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 152722346, states[0] = -86.718730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 163894784, states[0] = -86.877987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176003299, states[0] = 30.084054, states[40]= 0.173641
Saving checkpoint... 
Iteration: 187110586, states[0] = -27.663743, states[40]= 0.000538
Saving checkpoint... 
Iteration: 198834661, states[0] = -86.847891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 211886396, states[0] = -86.873509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 224168068, states[0] = -85.981813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235291266, states[0] = -86.812862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 247794565, states[0] = -86.815976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259938270, states[0] = -86.888800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271777513, states[0] = -86.798195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284107013, states[0] = -24.138563, states[40]= 0.000694
Saving checkpoint... 
Iteration: 296183813, states[0] = -86.629148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 308483451, states[0] = -86.897147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 320341027, states[0] = -86.851113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 332485335, states[0] = -86.897393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 344478068, states[0] = -86.896284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357483255, states[0] = -86.897062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370161269, states[0] = -83.360793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382356124, states[0] = -86.859440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396322855, states[0] = -86.839132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408642543, states[0] = -60.722606, states[40]= 0.000004
Saving checkpoint... 
Iteration: 422035762, states[0] = 18.196497, states[40]= 0.004764
Saving checkpoint... 
Iteration: 434215980, states[0] = -86.703867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 447795662, states[0] = -86.816710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 460416327, states[0] = -86.882865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 473277893, states[0] = -86.798394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486263576, states[0] = -86.781083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498704927, states[0] = -86.681689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 512127907, states[0] = -44.823831, states[40]= 0.000058
Saving checkpoint... 
Iteration: 525461458, states[0] = -86.893308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 538630351, states[0] = -47.364603, states[40]= 0.000039
Saving checkpoint... 
Iteration: 551213867, states[0] = -86.699639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 563999592, states[0] = -86.899131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 576851250, states[0] = -86.856714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590323747, states[0] = -86.839617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602959749, states[0] = -86.892930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 616415751, states[0] = -86.882579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 629880312, states[0] = -86.870354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 642638095, states[0] = -55.681811, states[40]= 0.000010
Saving checkpoint... 
Iteration: 655857316, states[0] = -86.859838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 667702812, states[0] = -86.677203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 681140754, states[0] = -58.661108, states[40]= 0.000006
Saving checkpoint... 
Iteration: 694167552, states[0] = -85.888718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 706748533, states[0] = -86.759920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 720054891, states[0] = 11.080818, states[40]= 0.004574
Saving checkpoint... 
Iteration: 733188866, states[0] = -86.646109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746271173, states[0] = -86.790369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 758873870, states[0] = -86.867548, states[40]= 0.000000
Saving checkpoint... 
Iteration: 772191350, states[0] = -86.652345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 785389298, states[0] = -86.873739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 798761794, states[0] = -86.778512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 811411102, states[0] = -86.881056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 825167413, states[0] = -85.862386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837343069, states[0] = -86.851907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 850970248, states[0] = -86.894613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 863486521, states[0] = -86.897145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 876835547, states[0] = -86.847300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889791508, states[0] = -86.812380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 901794647, states[0] = -86.815400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913640088, states[0] = -57.906104, states[40]= 0.000007
Saving checkpoint... 
Iteration: 926031413, states[0] = 19.606245, states[40]= 0.005016
Saving checkpoint... 
Iteration: 938227423, states[0] = -86.724933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 949996236, states[0] = -86.898406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 961250727, states[0] = -86.762977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 974344070, states[0] = -86.852385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 986633634, states[0] = -50.838323, states[40]= 0.000022
Saving checkpoint... 
Iteration: 998766694, states[0] = -86.784667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1011283062, states[0] = -86.803642, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1024080152, states[0] = -0.893374, states[40]= 0.003932
Saving checkpoint... 
Iteration: 1037069497, states[0] = 4.797982, states[40]= 0.004451
Saving checkpoint... 
Iteration: 1050692263, states[0] = -86.654273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1062731907, states[0] = -86.732764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1075217358, states[0] = -86.706040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1087839068, states[0] = -86.849322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1100477329, states[0] = -86.895579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112268030, states[0] = -86.786247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127162647, states[0] = -84.216582, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1140499720, states[0] = -86.898705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1153414152, states[0] = -86.881701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165793222, states[0] = -86.813833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1179299195, states[0] = -86.819410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1192371039, states[0] = -86.865970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205241287, states[0] = -86.748306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218064019, states[0] = 7.291837, states[40]= 0.004543
Saving checkpoint... 
Iteration: 1230816875, states[0] = -86.834075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244244413, states[0] = -86.753212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1257087038, states[0] = -5.602043, states[40]= 0.003129
Saving checkpoint... 
Iteration: 1269877444, states[0] = -86.868678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1282879540, states[0] = -86.869537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1295219733, states[0] = -86.710419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1308852639, states[0] = -86.856897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1321669197, states[0] = -86.139087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1334446618, states[0] = -86.889733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1347296502, states[0] = -86.816803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1360266769, states[0] = -86.784482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1373510148, states[0] = 23.174358, states[40]= 0.042325
Saving checkpoint... 
Iteration: 1386325588, states[0] = -86.840299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399722297, states[0] = -86.715172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412438994, states[0] = -86.887980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425599175, states[0] = -16.463601, states[40]= 0.001221
Saving checkpoint... 
Iteration: 1437803539, states[0] = -86.823069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1451034422, states[0] = 18.644733, states[40]= 0.004826
Saving checkpoint... 
Iteration: 1463400040, states[0] = -86.877026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1476703278, states[0] = -86.677537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489953214, states[0] = -86.890980, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.774340
 - CaMKt in component CaMK (millimolar): 0.006865
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.299937
 - nass in component intracellular_ions (millimolar): 6.299994
 - ki in component intracellular_ions (millimolar): 145.683713
 - kss in component intracellular_ions (millimolar): 145.683695
 - cansr in component intracellular_ions (millimolar): 1.292575
 - cajsr in component intracellular_ions (millimolar): 1.254112
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.008206
 - hf in component INa (dimensionless): 0.658585
 - hs in component INa (dimensionless): 0.658573
 - j in component INa (dimensionless): 0.658505
 - hsp in component INa (dimensionless): 0.410497
 - jp in component INa (dimensionless): 0.658459
 - mL in component INaL (dimensionless): 0.000232
 - hL in component INaL (dimensionless): 0.463093
 - hLp in component INaL (dimensionless): 0.237257
 - a in component Ito (dimensionless): 0.001078
 - iF in component Ito (dimensionless): 0.999459
 - iS in component Ito (dimensionless): 0.573191
 - ap in component Ito (dimensionless): 0.000549
 - iFp in component Ito (dimensionless): 0.999459
 - iSp in component Ito (dimensionless): 0.626133
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.931374
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999881
 - jca in component ICaL (dimensionless): 0.999976
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001516
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.407858
 - xs1 in component IKs (dimensionless): 0.251088
 - xs2 in component IKs (dimensionless): 0.000218
 - xk1 in component IK1 (dimensionless): 0.997037
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
19:14:19 (22838): called boinc_finish(0)

</stderr_txt>
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