𝕏

Task 55708670

Name HuVeMOp_20240630130118581586_ORdGradInc_k_25-BASE_MID-conf_686_2
Workunit 26323473
Created 1 Jul 2024, 21:14:19 UTC
Sent 2 Jul 2024, 14:06:21 UTC
Report deadline 5 Jul 2024, 14:06:21 UTC
Received 3 Jul 2024, 9:08:46 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 228562
Run time 2 hours 53 min 52 sec
CPU time 59 min 33 sec
Validate state Valid
Credit 47.22
Device peak FLOPS 4.84 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.76 MB
Peak swap size 6.28 MB
Peak disk usage 0.33 MB

Stderr output

<core_client_version>7.16.20</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630130118581586_ORdGradInc_k_25-BASE_MID-conf_686.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630130118581586_ORdGradInc_k_25-BASE_MID-conf_686_2_r445226521_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630130118581586_ORdGradInc_k_25-BASE_MID-conf_686_2_r445226521_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 110.926893
     * GNaL_b in INaL: 0.005201
     * Gto_b in Ito: 0.080317
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032523
     * GKs_b in IKs: 0.001880
     * GK1_b in IK1: 0.150712
     * Gncx_b in INaCa_i: 0.000954
     * Pnak_b in INaK: 68.970273
     * GKb_b in IKb: 0.003905
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.023346
     * celltype in environment: 2.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 11540405, states[0] = 31.467084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25731958, states[0] = -86.237615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34225723, states[0] = -86.203810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 44172603, states[0] = -47.061928, states[40]= 0.000103
Saving checkpoint... 
Iteration: 51775167, states[0] = -86.556257, states[40]= 0.000001
Saving checkpoint... 
Iteration: 57537485, states[0] = 30.655037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 64907287, states[0] = -86.883587, states[40]= 0.000002
Saving checkpoint... 
Iteration: 72963902, states[0] = -86.933610, states[40]= 0.000002
Saving checkpoint... 
Iteration: 80889782, states[0] = -86.879907, states[40]= 0.000002
Saving checkpoint... 
Iteration: 86261468, states[0] = -86.527020, states[40]= 0.000001
Saving checkpoint... 
Iteration: 91707609, states[0] = -86.004040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 99094072, states[0] = 8.537809, states[40]= 0.000022
Saving checkpoint... 
Iteration: 104553721, states[0] = 25.643898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 111900751, states[0] = -86.907530, states[40]= 0.000002
Saving checkpoint... 
Iteration: 117587759, states[0] = 11.448839, states[40]= 0.000012
Saving checkpoint... 
Iteration: 121779596, states[0] = -86.630621, states[40]= 0.000001
Saving checkpoint... 
Iteration: 128381934, states[0] = -86.888972, states[40]= 0.000002
Saving checkpoint... 
Iteration: 135126828, states[0] = -13.328420, states[40]= 0.000151
Saving checkpoint... 
Iteration: 143680754, states[0] = -64.078059, states[40]= 0.000014
Saving checkpoint... 
Iteration: 151318073, states[0] = -86.768341, states[40]= 0.000002
Saving checkpoint... 
Iteration: 163794028, states[0] = -86.692539, states[40]= 0.000001
Saving checkpoint... 
Iteration: 170615829, states[0] = -4.555059, states[40]= 0.000134
Saving checkpoint... 
Iteration: 174312555, states[0] = -86.753319, states[40]= 0.000002
Saving checkpoint... 
Iteration: 178948128, states[0] = -86.952652, states[40]= 0.000002
Saving checkpoint... 
Iteration: 183210981, states[0] = -86.149505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 188547057, states[0] = 27.627609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195216719, states[0] = -86.221602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201109764, states[0] = -0.511872, states[40]= 0.000097
Saving checkpoint... 
Iteration: 205414374, states[0] = -86.926621, states[40]= 0.000002
Saving checkpoint... 
Iteration: 210466162, states[0] = -86.962008, states[40]= 0.000002
Saving checkpoint... 
Iteration: 214752512, states[0] = -86.493697, states[40]= 0.000001
Saving checkpoint... 
Iteration: 219619890, states[0] = -7.754541, states[40]= 0.000150
Saving checkpoint... 
Iteration: 228337551, states[0] = -86.814963, states[40]= 0.000002
Saving checkpoint... 
Iteration: 233515525, states[0] = 30.747258, states[40]= -0.000000
Saving checkpoint... 
Iteration: 238750892, states[0] = -86.482686, states[40]= 0.000001
Saving checkpoint... 
Iteration: 243823353, states[0] = -86.780711, states[40]= 0.000002
Saving checkpoint... 
Iteration: 252795529, states[0] = -86.695440, states[40]= 0.000001
Saving checkpoint... 
Iteration: 259182105, states[0] = -66.356132, states[40]= 0.000011
Saving checkpoint... 
Iteration: 266582369, states[0] = 13.793040, states[40]= 0.000007
Saving checkpoint... 
Iteration: 273835030, states[0] = -86.807178, states[40]= 0.000002
Saving checkpoint... 
Iteration: 282623767, states[0] = -11.019578, states[40]= 0.000153
Saving checkpoint... 
Iteration: 292005301, states[0] = 21.762261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 300636438, states[0] = -21.908956, states[40]= 0.000252
Saving checkpoint... 
Iteration: 308517889, states[0] = 31.324364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 315060690, states[0] = 22.956287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 322415490, states[0] = -86.921898, states[40]= 0.000002
Saving checkpoint... 
Iteration: 329102837, states[0] = 3.533891, states[40]= 0.000057
Saving checkpoint... 
Iteration: 335880772, states[0] = -86.883205, states[40]= 0.000002
Saving checkpoint... 
Iteration: 341297157, states[0] = -86.696458, states[40]= 0.000001
Saving checkpoint... 
Iteration: 347542213, states[0] = 28.976746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 353013000, states[0] = 29.769022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359453929, states[0] = -86.947802, states[40]= 0.000002
Saving checkpoint... 
Iteration: 367392503, states[0] = -86.895986, states[40]= 0.000002
Saving checkpoint... 
Iteration: 372806312, states[0] = -86.725213, states[40]= 0.000002
Saving checkpoint... 
Iteration: 378139167, states[0] = -24.122183, states[40]= 0.000320
Saving checkpoint... 
Iteration: 383461193, states[0] = -86.950539, states[40]= 0.000002
Saving checkpoint... 
Iteration: 391223048, states[0] = -86.269943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396250548, states[0] = -86.471882, states[40]= 0.000001
Saving checkpoint... 
Iteration: 402064386, states[0] = 21.527483, states[40]= 0.000001
Saving checkpoint... 
Iteration: 409505904, states[0] = 23.091972, states[40]= -0.000000
Saving checkpoint... 
Iteration: 419125954, states[0] = -12.913755, states[40]= 0.000152
Saving checkpoint... 
Iteration: 425292324, states[0] = -86.674228, states[40]= 0.000001
Saving checkpoint... 
Iteration: 431811440, states[0] = -86.737584, states[40]= 0.000002
Saving checkpoint... 
Iteration: 438452324, states[0] = -86.942515, states[40]= 0.000002
Saving checkpoint... 
Iteration: 443906343, states[0] = -86.906592, states[40]= 0.000002
Saving checkpoint... 
Iteration: 450434121, states[0] = -86.929912, states[40]= 0.000002
Saving checkpoint... 
Iteration: 457676932, states[0] = -59.926003, states[40]= 0.000025
Saving checkpoint... 
Iteration: 463281082, states[0] = -86.627085, states[40]= 0.000001
Saving checkpoint... 
Iteration: 469354702, states[0] = -86.835761, states[40]= 0.000002
Saving checkpoint... 
Iteration: 474554015, states[0] = 25.375787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 480239253, states[0] = -86.391754, states[40]= 0.000001
Saving checkpoint... 
Iteration: 486021249, states[0] = 31.737842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491313732, states[0] = -86.740989, states[40]= 0.000002
Saving checkpoint... 
Iteration: 497079878, states[0] = 14.938572, states[40]= 0.000005
Saving checkpoint... 
Iteration: 502632498, states[0] = -18.604422, states[40]= 0.000180
Saving checkpoint... 
Iteration: 507285555, states[0] = -86.643276, states[40]= 0.000001
Saving checkpoint... 
Iteration: 512092468, states[0] = 8.961345, states[40]= 0.000021
Saving checkpoint... 
Iteration: 522193193, states[0] = -81.601143, states[40]= 0.000001
Saving checkpoint... 
Iteration: 528902829, states[0] = -86.898373, states[40]= 0.000002
Saving checkpoint... 
Iteration: 535220493, states[0] = -86.239114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547913858, states[0] = -86.908020, states[40]= 0.000002
Saving checkpoint... 
Iteration: 560372484, states[0] = -86.859339, states[40]= 0.000002
Saving checkpoint... 
Iteration: 568973515, states[0] = -86.946529, states[40]= 0.000002
Saving checkpoint... 
Iteration: 577612753, states[0] = -2.465964, states[40]= 0.000116
Saving checkpoint... 
Iteration: 587314380, states[0] = -86.737517, states[40]= 0.000002
Saving checkpoint... 
Iteration: 596821609, states[0] = -86.756803, states[40]= 0.000002
Saving checkpoint... 
Iteration: 607376969, states[0] = -86.863110, states[40]= 0.000002
Saving checkpoint... 
Iteration: 617887719, states[0] = -86.876494, states[40]= 0.000002
Saving checkpoint... 
Iteration: 628624480, states[0] = -11.611162, states[40]= 0.000152
Saving checkpoint... 
Iteration: 638808856, states[0] = -86.718299, states[40]= 0.000002
Saving checkpoint... 
Iteration: 649609755, states[0] = -0.513855, states[40]= 0.000097
Saving checkpoint... 
Iteration: 660300599, states[0] = -86.690530, states[40]= 0.000001
Saving checkpoint... 
Iteration: 670027409, states[0] = 31.657773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 681012301, states[0] = 29.421698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694740047, states[0] = -86.385208, states[40]= 0.000001
Saving checkpoint... 
Iteration: 704068096, states[0] = 20.039899, states[40]= 0.000001
Saving checkpoint... 
Iteration: 713495811, states[0] = -86.947728, states[40]= 0.000002
Saving checkpoint... 
Iteration: 727354390, states[0] = -86.820929, states[40]= 0.000002
Saving checkpoint... 
Iteration: 738108320, states[0] = 0.376381, states[40]= 0.000087
Saving checkpoint... 
Iteration: 748404887, states[0] = -86.888391, states[40]= 0.000002
Saving checkpoint... 
Iteration: 758678770, states[0] = -62.049694, states[40]= 0.000019
Saving checkpoint... 
Iteration: 768140909, states[0] = -25.497327, states[40]= 0.000359
Saving checkpoint... 
Iteration: 776794069, states[0] = -86.661046, states[40]= 0.000001
Saving checkpoint... 
Iteration: 785462661, states[0] = -86.929269, states[40]= 0.000002
Saving checkpoint... 
Iteration: 792756929, states[0] = -86.487804, states[40]= 0.000001
Saving checkpoint... 
Iteration: 800769374, states[0] = -86.554070, states[40]= 0.000001
Saving checkpoint... 
Iteration: 811169137, states[0] = -51.409149, states[40]= 0.000075
Saving checkpoint... 
Iteration: 819799668, states[0] = -86.678490, states[40]= 0.000001
Saving checkpoint... 
Iteration: 830623533, states[0] = -10.777154, states[40]= 0.000152
Saving checkpoint... 
Iteration: 840054874, states[0] = 25.086224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 848622203, states[0] = -9.643773, states[40]= 0.000152
Saving checkpoint... 
Iteration: 854388461, states[0] = -86.864369, states[40]= 0.000002
Saving checkpoint... 
Iteration: 866665664, states[0] = -47.850615, states[40]= 0.000114
Saving checkpoint... 
Iteration: 880479119, states[0] = -86.931957, states[40]= 0.000002
Saving checkpoint... 
Iteration: 897895678, states[0] = -86.870396, states[40]= 0.000002
Saving checkpoint... 
Iteration: 907892763, states[0] = -86.866539, states[40]= 0.000002
Saving checkpoint... 
Iteration: 918222012, states[0] = -86.230717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 928459899, states[0] = -86.919956, states[40]= 0.000002
Saving checkpoint... 
Iteration: 937074036, states[0] = 17.540342, states[40]= 0.000002
Saving checkpoint... 
Iteration: 945289119, states[0] = -86.632957, states[40]= 0.000001
Saving checkpoint... 
Iteration: 956815253, states[0] = -86.719453, states[40]= 0.000002
Saving checkpoint... 
Iteration: 965448088, states[0] = -86.911036, states[40]= 0.000002
Saving checkpoint... 
Iteration: 973119132, states[0] = -7.117086, states[40]= 0.000147
Saving checkpoint... 
Iteration: 979697760, states[0] = -84.637745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 991632119, states[0] = -18.238542, states[40]= 0.000175
Saving checkpoint... 
Iteration: 1002565497, states[0] = 21.099564, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1012872196, states[0] = -86.833983, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1020498924, states[0] = -86.932022, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1029898210, states[0] = -86.865932, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1039533281, states[0] = 30.928779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1050505714, states[0] = 22.707468, states[40]= -0.000001
Saving checkpoint... 
Iteration: 1062331320, states[0] = -86.755063, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1075204368, states[0] = -85.871298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089718167, states[0] = -86.185529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1105247996, states[0] = -86.415562, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1119910028, states[0] = -86.873022, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1131991431, states[0] = -86.923210, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1147498866, states[0] = -86.925046, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1162829232, states[0] = -86.744550, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1176801440, states[0] = -86.664589, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1191214539, states[0] = -86.141553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1207415544, states[0] = -86.873302, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1216891574, states[0] = -86.848126, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1230344944, states[0] = -86.775271, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1241997575, states[0] = -86.919430, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1253256186, states[0] = -86.457494, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1260270065, states[0] = -86.531674, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1272246030, states[0] = -86.393289, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1290233412, states[0] = -86.302541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1309173499, states[0] = -55.959600, states[40]= 0.000042
Saving checkpoint... 
Iteration: 1321208373, states[0] = -86.029042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338060971, states[0] = 22.872472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1349480875, states[0] = -86.907053, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1363037307, states[0] = 30.167012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1375163595, states[0] = -45.720560, states[40]= 0.000143
Saving checkpoint... 
Iteration: 1383414801, states[0] = -86.862983, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1395589968, states[0] = 10.218596, states[40]= 0.000016
Saving checkpoint... 
Iteration: 1404132152, states[0] = -18.231117, states[40]= 0.000174
Saving checkpoint... 
Iteration: 1417955311, states[0] = -86.890552, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1430957626, states[0] = -86.891146, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1443567957, states[0] = 20.113967, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1458056755, states[0] = 24.434078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1469747015, states[0] = -86.388593, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1483807040, states[0] = -86.665682, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1498744044, states[0] = -86.367196, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.782023
 - CaMKt in component CaMK (millimolar): 0.025275
 - cass in component intracellular_ions (millimolar): 0.000093
 - nai in component intracellular_ions (millimolar): 8.089190
 - nass in component intracellular_ions (millimolar): 8.089343
 - ki in component intracellular_ions (millimolar): 143.307071
 - kss in component intracellular_ions (millimolar): 143.307032
 - cansr in component intracellular_ions (millimolar): 2.064225
 - cajsr in component intracellular_ions (millimolar): 2.000075
 - cai in component intracellular_ions (millimolar): 0.000096
 - m in component INa (dimensionless): 0.008199
 - hf in component INa (dimensionless): 0.658868
 - hs in component INa (dimensionless): 0.658835
 - j in component INa (dimensionless): 0.658646
 - hsp in component INa (dimensionless): 0.410729
 - jp in component INa (dimensionless): 0.658510
 - mL in component INaL (dimensionless): 0.000232
 - hL in component INaL (dimensionless): 0.455153
 - hLp in component INaL (dimensionless): 0.221614
 - a in component Ito (dimensionless): 0.001078
 - iF in component Ito (dimensionless): 0.999460
 - iS in component Ito (dimensionless): 0.535576
 - ap in component Ito (dimensionless): 0.000549
 - iFp in component Ito (dimensionless): 0.999460
 - iSp in component Ito (dimensionless): 0.579071
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.878880
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999631
 - jca in component ICaL (dimensionless): 0.999943
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003932
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.508208
 - xs1 in component IKs (dimensionless): 0.330585
 - xs2 in component IKs (dimensionless): 0.000218
 - xk1 in component IK1 (dimensionless): 0.997036
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000002
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000002
11:01:27 (23296): called boinc_finish(0)

</stderr_txt>
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