𝕏

Task 55708655

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-Schmidt_333-conf_515_2
Workunit 26197700
Created 1 Jul 2024, 21:07:32 UTC
Sent 2 Jul 2024, 14:06:21 UTC
Report deadline 5 Jul 2024, 14:06:21 UTC
Received 3 Jul 2024, 11:49:10 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 228562
Run time 1 hours 57 min 23 sec
CPU time 45 min 58 sec
Validate state Valid
Credit 45.60
Device peak FLOPS 4.84 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.73 MB
Peak swap size 6.26 MB
Peak disk usage 0.13 MB

Stderr output

<core_client_version>7.16.20</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Schmidt_333-conf_515.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Schmidt_333-conf_515_2_r1169625960_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Schmidt_333-conf_515_2_r1169625960_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 95.611812
     * GNaL_b in INaL: 0.007277
     * Gto_b in Ito: 0.075950
     * PCa_b in ICaL: 0.000079
     * GKr_b in IKr: 0.030866
     * GKs_b in IKs: 0.001945
     * GK1_b in IK1: 0.151418
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 68.855351
     * GKb_b in IKb: 0.003822
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.045805
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 13606046, states[0] = -51.631284, states[40]= 0.000126
Saving checkpoint... 
Iteration: 25592142, states[0] = -35.273619, states[40]= 0.000431
Saving checkpoint... 
Iteration: 36126172, states[0] = -81.108351, states[40]= 0.000002
Saving checkpoint... 
Iteration: 42497439, states[0] = 34.311975, states[40]= 1.150534
Saving checkpoint... 
Iteration: 56254465, states[0] = -35.645141, states[40]= 0.000302
Saving checkpoint... 
Iteration: 66433434, states[0] = -53.070808, states[40]= 0.000074
Saving checkpoint... 
Iteration: 83124605, states[0] = -83.608358, states[40]= 0.000001
Saving checkpoint... 
Iteration: 97141944, states[0] = -84.891994, states[40]= 0.000001
Saving checkpoint... 
Iteration: 113785715, states[0] = -82.846705, states[40]= 0.000001
Saving checkpoint... 
Iteration: 128814556, states[0] = -85.012520, states[40]= 0.000001
Saving checkpoint... 
Iteration: 142637637, states[0] = -84.901237, states[40]= 0.000001
Saving checkpoint... 
Iteration: 154863043, states[0] = 15.877786, states[40]= 0.000011
Saving checkpoint... 
Iteration: 166832091, states[0] = 29.792160, states[40]= 0.008800
Saving checkpoint... 
Iteration: 177464815, states[0] = -84.859755, states[40]= 0.000001
Saving checkpoint... 
Iteration: 191700071, states[0] = 10.859756, states[40]= 0.000037
Saving checkpoint... 
Iteration: 204294362, states[0] = -84.839627, states[40]= 0.000001
Saving checkpoint... 
Iteration: 219803663, states[0] = -84.989551, states[40]= 0.000001
Saving checkpoint... 
Iteration: 230390320, states[0] = -18.790669, states[40]= 0.000263
Saving checkpoint... 
Iteration: 242228005, states[0] = -26.480834, states[40]= 0.000281
Saving checkpoint... 
Iteration: 252828310, states[0] = 28.818781, states[40]= 0.001510
Saving checkpoint... 
Iteration: 262318264, states[0] = 29.599186, states[40]= 0.042960
Saving checkpoint... 
Iteration: 276468435, states[0] = -85.029062, states[40]= 0.000001
Saving checkpoint... 
Iteration: 288502156, states[0] = 24.167115, states[40]= 0.000033
Saving checkpoint... 
Iteration: 298858827, states[0] = 8.783518, states[40]= 0.000058
Saving checkpoint... 
Iteration: 314811347, states[0] = 29.244074, states[40]= 0.079788
Saving checkpoint... 
Iteration: 328633524, states[0] = -85.064175, states[40]= 0.000001
Saving checkpoint... 
Iteration: 341955339, states[0] = -84.948676, states[40]= 0.000001
Saving checkpoint... 
Iteration: 356064756, states[0] = -45.851589, states[40]= 0.000133
Saving checkpoint... 
Iteration: 369635923, states[0] = 28.716699, states[40]= 0.264062
Saving checkpoint... 
Iteration: 385997759, states[0] = 21.236820, states[40]= 0.000007
Saving checkpoint... 
Iteration: 399991959, states[0] = 23.667534, states[40]= 0.000023
Saving checkpoint... 
Iteration: 418968442, states[0] = 29.440278, states[40]= 0.058289
Saving checkpoint... 
Iteration: 432692454, states[0] = -3.846965, states[40]= 0.000296
Saving checkpoint... 
Iteration: 439770431, states[0] = -84.818526, states[40]= 0.000001
Saving checkpoint... 
Iteration: 451477563, states[0] = 27.984689, states[40]= 0.000622
Saving checkpoint... 
Iteration: 466250357, states[0] = -82.833002, states[40]= 0.000001
Saving checkpoint... 
Iteration: 479372039, states[0] = -27.933699, states[40]= 0.000286
Saving checkpoint... 
Iteration: 494249398, states[0] = -83.500707, states[40]= 0.000001
Saving checkpoint... 
Iteration: 507759563, states[0] = -84.722979, states[40]= 0.000001
Saving checkpoint... 
Iteration: 529723654, states[0] = -58.269371, states[40]= 0.000039
Saving checkpoint... 
Iteration: 544291911, states[0] = 29.823273, states[40]= 0.021607
Saving checkpoint... 
Iteration: 564875597, states[0] = -43.769866, states[40]= 0.000156
Saving checkpoint... 
Iteration: 579643960, states[0] = 21.864558, states[40]= 0.000008
Saving checkpoint... 
Iteration: 592664140, states[0] = 7.745148, states[40]= 0.000071
Saving checkpoint... 
Iteration: 603538664, states[0] = -44.109771, states[40]= 0.000152
Saving checkpoint... 
Iteration: 618999733, states[0] = 3.689066, states[40]= 0.000141
Saving checkpoint... 
Iteration: 627530711, states[0] = -36.957331, states[40]= 0.000242
Saving checkpoint... 
Iteration: 645318174, states[0] = 13.109336, states[40]= 0.000022
Saving checkpoint... 
Iteration: 663253306, states[0] = -84.886736, states[40]= 0.000001
Saving checkpoint... 
Iteration: 674949895, states[0] = 29.531684, states[40]= 0.004290
Saving checkpoint... 
Iteration: 688694180, states[0] = -40.722763, states[40]= 0.000195
Saving checkpoint... 
Iteration: 698378766, states[0] = -65.571297, states[40]= 0.000017
Saving checkpoint... 
Iteration: 710473270, states[0] = 16.441950, states[40]= 0.000009
Saving checkpoint... 
Iteration: 720057543, states[0] = -82.439119, states[40]= 0.000001
Saving checkpoint... 
Iteration: 735475497, states[0] = 13.336283, states[40]= 0.000021
Saving checkpoint... 
Iteration: 746426760, states[0] = 33.889095, states[40]= 1.117155
Saving checkpoint... 
Iteration: 757821618, states[0] = 1.451856, states[40]= 0.000189
Saving checkpoint... 
Iteration: 773790442, states[0] = 22.298293, states[40]= 0.000010
Saving checkpoint... 
Iteration: 786783639, states[0] = 25.205805, states[40]= 0.000066
Saving checkpoint... 
Iteration: 801193614, states[0] = -54.444984, states[40]= 0.000059
Saving checkpoint... 
Iteration: 809454102, states[0] = 21.986592, states[40]= 0.000009
Saving checkpoint... 
Iteration: 820596133, states[0] = 29.666587, states[40]= 0.037408
Saving checkpoint... 
Iteration: 830604559, states[0] = 28.610774, states[40]= 0.001171
Saving checkpoint... 
Iteration: 845091328, states[0] = 29.170315, states[40]= 0.089697
Saving checkpoint... 
Iteration: 867922384, states[0] = 29.171995, states[40]= 0.089495
Saving checkpoint... 
Iteration: 885370425, states[0] = -79.491144, states[40]= 0.000002
Saving checkpoint... 
Iteration: 896470793, states[0] = 4.732682, states[40]= 0.000121
Saving checkpoint... 
Iteration: 911542254, states[0] = -83.787529, states[40]= 0.000001
Saving checkpoint... 
Iteration: 923033622, states[0] = -79.774123, states[40]= 0.000002
Saving checkpoint... 
Iteration: 936925942, states[0] = 29.012290, states[40]= 0.001889
Saving checkpoint... 
Iteration: 951735826, states[0] = -85.005452, states[40]= 0.000001
Saving checkpoint... 
Iteration: 965403236, states[0] = -85.026597, states[40]= 0.000001
Saving checkpoint... 
Iteration: 978413639, states[0] = 29.661752, states[40]= 0.038015
Saving checkpoint... 
Iteration: 995226654, states[0] = -84.949262, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1005402611, states[0] = 32.098297, states[40]= 0.773305
Saving checkpoint... 
Iteration: 1013982325, states[0] = -23.918535, states[40]= 0.000268
Saving checkpoint... 
Iteration: 1025864194, states[0] = -83.786525, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1036044070, states[0] = -84.780751, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1054257500, states[0] = 24.906426, states[40]= 0.000053
Saving checkpoint... 
Iteration: 1070488109, states[0] = -39.112001, states[40]= 0.000214
Saving checkpoint... 
Iteration: 1081746736, states[0] = 28.405441, states[40]= 0.000933
Saving checkpoint... 
Iteration: 1098238398, states[0] = 29.841485, states[40]= 0.010735
Saving checkpoint... 
Iteration: 1112001875, states[0] = -62.451286, states[40]= 0.000025
Saving checkpoint... 
Iteration: 1129708075, states[0] = -84.877707, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1142536050, states[0] = -84.818723, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1154347570, states[0] = -82.456985, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1166512748, states[0] = -82.314183, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1176002904, states[0] = -73.068595, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1187147236, states[0] = -44.408773, states[40]= 0.000148
Saving checkpoint... 
Iteration: 1203320096, states[0] = -54.446970, states[40]= 0.000059
Saving checkpoint... 
Iteration: 1213637921, states[0] = -35.812389, states[40]= 0.000253
Saving checkpoint... 
Iteration: 1227330375, states[0] = -72.019287, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1233557683, states[0] = 29.862298, states[40]= 0.012983
Saving checkpoint... 
Iteration: 1246306354, states[0] = -42.311735, states[40]= 0.000174
Saving checkpoint... 
Iteration: 1258050338, states[0] = 29.250272, states[40]= 0.079903
Saving checkpoint... 
Iteration: 1269600634, states[0] = 4.324525, states[40]= 0.000128
Saving checkpoint... 
Iteration: 1287391921, states[0] = 28.712865, states[40]= 0.001299
Saving checkpoint... 
Iteration: 1300322553, states[0] = -71.244854, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1315909338, states[0] = 18.556931, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1327210709, states[0] = 29.397919, states[40]= 0.063456
Saving checkpoint... 
Iteration: 1338612030, states[0] = -17.588258, states[40]= 0.000267
Saving checkpoint... 
Iteration: 1352590726, states[0] = 5.686556, states[40]= 0.000104
Saving checkpoint... 
Iteration: 1368281040, states[0] = -25.014531, states[40]= 0.000273
Saving checkpoint... 
Iteration: 1380207441, states[0] = 29.756527, states[40]= 0.029812
Saving checkpoint... 
Iteration: 1391107226, states[0] = -18.219194, states[40]= 0.000264
Saving checkpoint... 
Iteration: 1404038746, states[0] = 29.794970, states[40]= 0.026127
Saving checkpoint... 
Iteration: 1415049085, states[0] = 27.525242, states[40]= 0.000400
Saving checkpoint... 
Iteration: 1423998310, states[0] = -84.557077, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1437110711, states[0] = -29.371611, states[40]= 0.000288
Saving checkpoint... 
Iteration: 1451046098, states[0] = 27.272086, states[40]= 0.000321
Saving checkpoint... 
Iteration: 1462712393, states[0] = 26.930979, states[40]= 0.000241
Saving checkpoint... 
Iteration: 1474430234, states[0] = -15.369159, states[40]= 0.000283
Saving checkpoint... 
Iteration: 1492706259, states[0] = 28.193341, states[40]= 0.000745
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -84.872347
 - CaMKt in component CaMK (millimolar): 0.213278
 - cass in component intracellular_ions (millimolar): 0.000171
 - nai in component intracellular_ions (millimolar): 7.262041
 - nass in component intracellular_ions (millimolar): 7.262388
 - ki in component intracellular_ions (millimolar): 143.875533
 - kss in component intracellular_ions (millimolar): 143.875498
 - cansr in component intracellular_ions (millimolar): 3.289480
 - cajsr in component intracellular_ions (millimolar): 1.886298
 - cai in component intracellular_ions (millimolar): 0.000160
 - m in component INa (dimensionless): 0.009932
 - hf in component INa (dimensionless): 0.585264
 - hs in component INa (dimensionless): 0.584155
 - j in component INa (dimensionless): 0.549405
 - hsp in component INa (dimensionless): 0.331711
 - jp in component INa (dimensionless): 0.504164
 - mL in component INaL (dimensionless): 0.000333
 - hL in component INaL (dimensionless): 0.175579
 - hLp in component INaL (dimensionless): 0.071011
 - a in component Ito (dimensionless): 0.001226
 - iF in component Ito (dimensionless): 0.999240
 - iS in component Ito (dimensionless): 0.127808
 - ap in component Ito (dimensionless): 0.000625
 - iFp in component Ito (dimensionless): 0.999241
 - iSp in component Ito (dimensionless): 0.142209
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.672855
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.926259
 - jca in component ICaL (dimensionless): 0.908976
 - ffp in component ICaL (dimensionless): 0.998718
 - fcafp in component ICaL (dimensionless): 0.999933
 - nca in component ICaL (dimensionless): 0.040906
 - xrf in component IKr (dimensionless): 0.109291
 - xrs in component IKr (dimensionless): 0.876742
 - xs1 in component IKs (dimensionless): 0.573918
 - xs2 in component IKs (dimensionless): 0.008213
 - xk1 in component IK1 (dimensionless): 0.996733
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
12:58:51 (23352): called boinc_finish(0)

</stderr_txt>
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