𝕏

Task 55708652

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pieske_500-conf_215_2
Workunit 26197637
Created 1 Jul 2024, 21:07:32 UTC
Sent 2 Jul 2024, 14:06:21 UTC
Report deadline 5 Jul 2024, 14:06:21 UTC
Received 3 Jul 2024, 9:08:46 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 228562
Run time 2 hours 55 min 17 sec
CPU time 59 min 17 sec
Validate state Valid
Credit 47.26
Device peak FLOPS 4.84 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.77 MB
Peak swap size 6.27 MB
Peak disk usage 0.18 MB

Stderr output

<core_client_version>7.16.20</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pieske_500-conf_215.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pieske_500-conf_215_2_r962057930_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Pieske_500-conf_215_2_r962057930_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 90.753222
     * GNaL_b in INaL: 0.005640
     * Gto_b in Ito: 0.086885
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033429
     * GKs_b in IKs: 0.001978
     * GK1_b in IK1: 0.157008
     * Gncx_b in INaCa_i: 0.000961
     * Pnak_b in INaK: 67.865082
     * GKb_b in IKb: 0.003834
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.020283
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 6000.000000
     * CL_0 in membrane: 500.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499750000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 11206967, states[0] = -87.426498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23861560, states[0] = -66.303899, states[40]= 0.000002
Saving checkpoint... 
Iteration: 34922895, states[0] = -87.307122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 45450524, states[0] = -87.370460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 53451256, states[0] = -87.369713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 61139811, states[0] = -87.134658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69018998, states[0] = 20.933196, states[40]= 0.009773
Saving checkpoint... 
Iteration: 77534214, states[0] = 14.530717, states[40]= 0.006105
Saving checkpoint... 
Iteration: 83996134, states[0] = -87.438817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 91595427, states[0] = -44.035355, states[40]= 0.000075
Saving checkpoint... 
Iteration: 96201862, states[0] = -87.365781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 101251465, states[0] = 38.992871, states[40]= 0.081068
Saving checkpoint... 
Iteration: 109294167, states[0] = 9.039097, states[40]= 0.005733
Saving checkpoint... 
Iteration: 115464523, states[0] = -87.389540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121040716, states[0] = 11.045442, states[40]= 0.005842
Saving checkpoint... 
Iteration: 127244350, states[0] = -87.434705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 136006716, states[0] = 24.390215, states[40]= 0.097906
Saving checkpoint... 
Iteration: 141606359, states[0] = -58.009715, states[40]= 0.000008
Saving checkpoint... 
Iteration: 145148821, states[0] = -87.211716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 153292022, states[0] = 10.304786, states[40]= 0.005800
Saving checkpoint... 
Iteration: 160755855, states[0] = 25.182883, states[40]= 0.118082
Saving checkpoint... 
Iteration: 167703403, states[0] = -87.367432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 171213102, states[0] = -87.386187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 174743477, states[0] = -87.433077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 179287919, states[0] = 12.602275, states[40]= 0.005940
Saving checkpoint... 
Iteration: 184603823, states[0] = -54.650742, states[40]= 0.000015
Saving checkpoint... 
Iteration: 188749633, states[0] = -87.440693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194990108, states[0] = -87.428560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 200314970, states[0] = -6.855690, states[40]= 0.003542
Saving checkpoint... 
Iteration: 205691887, states[0] = -87.342106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 211632875, states[0] = -86.745913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 216367478, states[0] = -74.234225, states[40]= 0.000001
Saving checkpoint... 
Iteration: 220380837, states[0] = -86.421038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226025080, states[0] = 18.789613, states[40]= 0.007074
Saving checkpoint... 
Iteration: 230219316, states[0] = -87.396971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 233082630, states[0] = -28.244207, states[40]= 0.000533
Saving checkpoint... 
Iteration: 241034513, states[0] = 14.405555, states[40]= 0.006091
Saving checkpoint... 
Iteration: 246342432, states[0] = -40.255899, states[40]= 0.000128
Saving checkpoint... 
Iteration: 253369425, states[0] = -77.205368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260724360, states[0] = -87.405267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 267920062, states[0] = -87.284531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275485157, states[0] = -87.421565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 282299439, states[0] = 5.777962, states[40]= 0.005546
Saving checkpoint... 
Iteration: 291834868, states[0] = -30.994843, states[40]= 0.000407
Saving checkpoint... 
Iteration: 296469657, states[0] = -87.397448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 302037537, states[0] = 12.810200, states[40]= 0.005955
Saving checkpoint... 
Iteration: 307589583, states[0] = -36.762889, states[40]= 0.000206
Saving checkpoint... 
Iteration: 313916697, states[0] = -87.274371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321905204, states[0] = -87.236792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 327903946, states[0] = -87.232223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 334897136, states[0] = -87.202513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 342163550, states[0] = -87.264567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 347726820, states[0] = -87.409046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354357811, states[0] = -59.951939, states[40]= 0.000006
Saving checkpoint... 
Iteration: 358980607, states[0] = -87.414821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 364821614, states[0] = -14.560465, states[40]= 0.001814
Saving checkpoint... 
Iteration: 372824516, states[0] = -18.162712, states[40]= 0.001279
Saving checkpoint... 
Iteration: 380231060, states[0] = -87.415469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 385229194, states[0] = -87.412656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 392386446, states[0] = -87.021465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 402571617, states[0] = -14.564089, states[40]= 0.001813
Saving checkpoint... 
Iteration: 411756774, states[0] = 24.348813, states[40]= 0.096608
Saving checkpoint... 
Iteration: 418817000, states[0] = -9.076758, states[40]= 0.002996
Saving checkpoint... 
Iteration: 426640908, states[0] = -87.145372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 433659551, states[0] = -87.251535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 440357682, states[0] = -59.776128, states[40]= 0.000006
Saving checkpoint... 
Iteration: 446101785, states[0] = -52.006809, states[40]= 0.000022
Saving checkpoint... 
Iteration: 452888115, states[0] = -87.084158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 460094116, states[0] = -42.333296, states[40]= 0.000096
Saving checkpoint... 
Iteration: 466248769, states[0] = -87.439215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 472985105, states[0] = -87.421231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 479311119, states[0] = -3.063929, states[40]= 0.004411
Saving checkpoint... 
Iteration: 483995076, states[0] = -87.434606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 490067430, states[0] = -9.565437, states[40]= 0.002877
Saving checkpoint... 
Iteration: 496136700, states[0] = -87.032698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502053736, states[0] = 2.856229, states[40]= 0.005308
Saving checkpoint... 
Iteration: 506642160, states[0] = -87.162347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514038838, states[0] = 12.101160, states[40]= 0.005906
Saving checkpoint... 
Iteration: 521182884, states[0] = -87.319579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 529118734, states[0] = -76.165895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 533462907, states[0] = -87.385227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542111864, states[0] = -65.659596, states[40]= 0.000002
Saving checkpoint... 
Iteration: 552147692, states[0] = -87.205226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 560741263, states[0] = -87.429566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 571792226, states[0] = 10.190018, states[40]= 0.005794
Saving checkpoint... 
Iteration: 580566292, states[0] = -8.284839, states[40]= 0.003190
Saving checkpoint... 
Iteration: 589370403, states[0] = -78.618491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599814615, states[0] = -6.480576, states[40]= 0.003634
Saving checkpoint... 
Iteration: 610007340, states[0] = 23.984367, states[40]= 0.084686
Saving checkpoint... 
Iteration: 619826072, states[0] = -20.104578, states[40]= 0.001070
Saving checkpoint... 
Iteration: 629064080, states[0] = -5.927211, states[40]= 0.003768
Saving checkpoint... 
Iteration: 639429012, states[0] = -87.309241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 650583530, states[0] = -29.350783, states[40]= 0.000480
Saving checkpoint... 
Iteration: 660343784, states[0] = -41.922088, states[40]= 0.000101
Saving checkpoint... 
Iteration: 668733501, states[0] = -87.418677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 679760441, states[0] = 22.929611, states[40]= 0.040295
Saving checkpoint... 
Iteration: 692796433, states[0] = 7.679764, states[40]= 0.005660
Saving checkpoint... 
Iteration: 698788896, states[0] = 12.069337, states[40]= 0.005904
Saving checkpoint... 
Iteration: 716006814, states[0] = 24.319892, states[40]= 0.095727
Saving checkpoint... 
Iteration: 728302217, states[0] = 3.921478, states[40]= 0.005407
Saving checkpoint... 
Iteration: 738609780, states[0] = -62.673663, states[40]= 0.000004
Saving checkpoint... 
Iteration: 746987730, states[0] = -87.424550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 757194873, states[0] = -87.348190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 764111587, states[0] = -65.255259, states[40]= 0.000003
Saving checkpoint... 
Iteration: 774063292, states[0] = -5.132213, states[40]= 0.003956
Saving checkpoint... 
Iteration: 785276984, states[0] = 17.991178, states[40]= 0.006743
Saving checkpoint... 
Iteration: 795119408, states[0] = -77.177274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804615286, states[0] = -70.816505, states[40]= 0.000001
Saving checkpoint... 
Iteration: 813729605, states[0] = -87.412723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824606598, states[0] = -58.311817, states[40]= 0.000008
Saving checkpoint... 
Iteration: 835151624, states[0] = -87.222649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 845153471, states[0] = -87.229779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854574562, states[0] = -18.219273, states[40]= 0.001272
Saving checkpoint... 
Iteration: 866219516, states[0] = -87.396466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 877287056, states[0] = 13.069309, states[40]= 0.005974
Saving checkpoint... 
Iteration: 886572238, states[0] = -15.329345, states[40]= 0.001682
Saving checkpoint... 
Iteration: 898482379, states[0] = -87.416745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 908244128, states[0] = -87.432848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 917557061, states[0] = 0.367948, states[40]= 0.005009
Saving checkpoint... 
Iteration: 923236512, states[0] = -87.422630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932880501, states[0] = -86.346991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 943460511, states[0] = -87.380238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 951567966, states[0] = -10.181863, states[40]= 0.002730
Saving checkpoint... 
Iteration: 958606400, states[0] = -58.046331, states[40]= 0.000008
Saving checkpoint... 
Iteration: 970003627, states[0] = 29.663300, states[40]= 0.159312
Saving checkpoint... 
Iteration: 979770031, states[0] = 20.636963, states[40]= 0.009004
Saving checkpoint... 
Iteration: 990313296, states[0] = -5.135913, states[40]= 0.003955
Saving checkpoint... 
Iteration: 998817037, states[0] = -9.117725, states[40]= 0.002986
Saving checkpoint... 
Iteration: 1008532648, states[0] = 15.350036, states[40]= 0.006198
Saving checkpoint... 
Iteration: 1019140410, states[0] = -87.136369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1028951877, states[0] = -87.363013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041679772, states[0] = -87.310748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1051085393, states[0] = -31.637051, states[40]= 0.000380
Saving checkpoint... 
Iteration: 1062625719, states[0] = -84.309554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1072879282, states[0] = -86.024467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1083949879, states[0] = -87.358735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095582429, states[0] = -27.994318, states[40]= 0.000545
Saving checkpoint... 
Iteration: 1111955694, states[0] = -87.370680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1128682006, states[0] = -87.316513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141795725, states[0] = 8.114019, states[40]= 0.005684
Saving checkpoint... 
Iteration: 1158357815, states[0] = -59.955080, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1170815201, states[0] = -7.098419, states[40]= 0.003482
Saving checkpoint... 
Iteration: 1186691962, states[0] = -87.340959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201761511, states[0] = 22.711298, states[40]= 0.031579
Saving checkpoint... 
Iteration: 1211095538, states[0] = -44.098131, states[40]= 0.000074
Saving checkpoint... 
Iteration: 1226303906, states[0] = 2.735129, states[40]= 0.005296
Saving checkpoint... 
Iteration: 1239645831, states[0] = -87.193497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250707984, states[0] = -87.375003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263285228, states[0] = 14.035865, states[40]= 0.006055
Saving checkpoint... 
Iteration: 1276283732, states[0] = 14.805572, states[40]= 0.006133
Saving checkpoint... 
Iteration: 1291763934, states[0] = 22.236214, states[40]= 0.019296
Saving checkpoint... 
Iteration: 1311862355, states[0] = -66.377632, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1324868900, states[0] = -76.413922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338196748, states[0] = -87.351615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1352568708, states[0] = -11.048739, states[40]= 0.002529
Saving checkpoint... 
Iteration: 1365315501, states[0] = -7.419833, states[40]= 0.003403
Saving checkpoint... 
Iteration: 1376923114, states[0] = -87.291933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1391038430, states[0] = 12.325546, states[40]= 0.005921
Saving checkpoint... 
Iteration: 1405313562, states[0] = -5.401022, states[40]= 0.003893
Saving checkpoint... 
Iteration: 1418103072, states[0] = -53.667033, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1431241876, states[0] = -87.429246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1445181606, states[0] = -87.315057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1459194062, states[0] = -87.345438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471477132, states[0] = -87.408073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483067996, states[0] = -10.215834, states[40]= 0.002722
Saving checkpoint... 
Iteration: 1491895498, states[0] = -87.190954, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -87.315115
 - CaMKt in component CaMK (millimolar): 0.020778
 - cass in component intracellular_ions (millimolar): 0.000096
 - nai in component intracellular_ions (millimolar): 6.820256
 - nass in component intracellular_ions (millimolar): 6.820358
 - ki in component intracellular_ions (millimolar): 145.128213
 - kss in component intracellular_ions (millimolar): 145.128186
 - cansr in component intracellular_ions (millimolar): 1.458332
 - cajsr in component intracellular_ions (millimolar): 1.233461
 - cai in component intracellular_ions (millimolar): 0.000095
 - m in component INa (dimensionless): 0.007771
 - hf in component INa (dimensionless): 0.678276
 - hs in component INa (dimensionless): 0.678165
 - j in component INa (dimensionless): 0.677418
 - hsp in component INa (dimensionless): 0.431799
 - jp in component INa (dimensionless): 0.675500
 - mL in component INaL (dimensionless): 0.000209
 - hL in component INaL (dimensionless): 0.388477
 - hLp in component INaL (dimensionless): 0.182394
 - a in component Ito (dimensionless): 0.001040
 - iF in component Ito (dimensionless): 0.999508
 - iS in component Ito (dimensionless): 0.295276
 - ap in component Ito (dimensionless): 0.000530
 - iFp in component Ito (dimensionless): 0.999508
 - iSp in component Ito (dimensionless): 0.343972
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.860490
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.991526
 - jca in component ICaL (dimensionless): 0.991619
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004419
 - xrf in component IKr (dimensionless): 0.001628
 - xrs in component IKr (dimensionless): 0.656162
 - xs1 in component IKs (dimensionless): 0.380146
 - xs2 in component IKs (dimensionless): 0.000213
 - xk1 in component IK1 (dimensionless): 0.996906
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
11:02:52 (22600): called boinc_finish(0)

</stderr_txt>
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