𝕏

Task 55708558

Name HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pueyo_APDR-conf_733_2
Workunit 26157868
Created 1 Jul 2024, 20:26:06 UTC
Sent 2 Jul 2024, 14:05:28 UTC
Report deadline 5 Jul 2024, 23:41:28 UTC
Received 5 Jul 2024, 4:04:11 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 219798
Run time 2 hours 52 min 15 sec
CPU time 2 hours 47 min 38 sec
Validate state Valid
Credit 61.79
Device peak FLOPS 2.33 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.72 MB
Peak swap size 6.40 MB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pueyo_APDR-conf_733.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pueyo_APDR-conf_733_2_r1795678577_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628065214404275_ORdGradInc_k_25-Pueyo_APDR-conf_733_2_r1795678577_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 98.493880
     * GNaL_b in INaL: 0.004585
     * Gto_b in Ito: 0.091264
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.033293
     * GKs_b in IKs: 0.001861
     * GK1_b in IK1: 0.155420
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 68.112263
     * GKb_b in IKb: 0.003689
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.040900
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13146868, states[0] = -83.483053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25720627, states[0] = -94.949476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39297566, states[0] = -95.021851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 52889790, states[0] = -95.058320, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65228480, states[0] = -94.922393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 78820770, states[0] = -95.013988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 92467669, states[0] = -95.060618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 106070527, states[0] = 1.154476, states[40]= 0.004334
Saving checkpoint... 
Iteration: 119687798, states[0] = -94.829162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133281822, states[0] = -94.975072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 146750703, states[0] = -94.939811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 160060089, states[0] = 6.339006, states[40]= 0.004697
Saving checkpoint... 
Iteration: 173672446, states[0] = -94.741449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 187240620, states[0] = -94.924932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 200410374, states[0] = -95.041609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213799594, states[0] = -94.988291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 226326506, states[0] = -95.006773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236556026, states[0] = 8.109082, states[40]= 0.004759
Saving checkpoint... 
Iteration: 247225464, states[0] = -94.900909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 257397246, states[0] = -95.037526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270393679, states[0] = -95.036387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284023457, states[0] = 19.459662, states[40]= 0.007305
Saving checkpoint... 
Iteration: 297658112, states[0] = -91.514556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311287834, states[0] = -94.978197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324687136, states[0] = -94.824034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 338342017, states[0] = -95.015211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 351975950, states[0] = -95.054476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 365594855, states[0] = -18.019480, states[40]= 0.001103
Saving checkpoint... 
Iteration: 379109708, states[0] = -32.835627, states[40]= 0.000315
Saving checkpoint... 
Iteration: 391989977, states[0] = -95.056375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 405604115, states[0] = -27.239396, states[40]= 0.000558
Saving checkpoint... 
Iteration: 419191643, states[0] = -94.834464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 431545938, states[0] = 12.148724, states[40]= 0.004900
Saving checkpoint... 
Iteration: 445106479, states[0] = -29.600284, states[40]= 0.000450
Saving checkpoint... 
Iteration: 458723760, states[0] = -94.897799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 471836742, states[0] = -95.012315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 485418629, states[0] = -95.043245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498962476, states[0] = -95.052265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 512546909, states[0] = 11.775512, states[40]= 0.004881
Saving checkpoint... 
Iteration: 526156046, states[0] = -89.446040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539793557, states[0] = -94.982954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553346788, states[0] = -95.017473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566957383, states[0] = -95.051350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579838100, states[0] = -95.012977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593391791, states[0] = -95.035524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 607039748, states[0] = 14.457429, states[40]= 0.005085
Saving checkpoint... 
Iteration: 619301765, states[0] = -94.989484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 632885877, states[0] = -95.033537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646472598, states[0] = -95.053775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 659862665, states[0] = -95.024678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673494507, states[0] = -95.056755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686836442, states[0] = -95.012007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 700434619, states[0] = -95.046828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 714067322, states[0] = 2.955821, states[40]= 0.004498
Saving checkpoint... 
Iteration: 727691763, states[0] = -94.834525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 741308451, states[0] = -94.994378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 754500663, states[0] = 39.787738, states[40]= 0.004685
Saving checkpoint... 
Iteration: 767450585, states[0] = -95.049989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 781052067, states[0] = 9.741002, states[40]= 0.004807
Saving checkpoint... 
Iteration: 794662513, states[0] = -93.791537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 806927815, states[0] = -95.045238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 820495056, states[0] = -95.056724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 834096569, states[0] = -19.722856, states[40]= 0.000959
Saving checkpoint... 
Iteration: 847730453, states[0] = -94.908580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861336259, states[0] = -95.011790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 874809015, states[0] = -94.994693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 888082205, states[0] = -6.361389, states[40]= 0.003084
Saving checkpoint... 
Iteration: 901691764, states[0] = -94.834410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 915310077, states[0] = -94.995422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 928895178, states[0] = -95.036374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 942515118, states[0] = 20.982332, states[40]= 0.017538
Saving checkpoint... 
Iteration: 955467571, states[0] = -95.052789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 969069743, states[0] = 1.702472, states[40]= 0.004387
Saving checkpoint... 
Iteration: 982320715, states[0] = -95.002524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 994620656, states[0] = -44.063962, states[40]= 0.000065
Saving checkpoint... 
Iteration: 1008206404, states[0] = -94.865315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1021765681, states[0] = -94.955684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1035390046, states[0] = -95.034661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1049048342, states[0] = 11.219349, states[40]= 0.004857
Saving checkpoint... 
Iteration: 1062470857, states[0] = -95.053231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1076129727, states[0] = -53.866829, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1089775457, states[0] = -94.965976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103450839, states[0] = -95.049812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1117057928, states[0] = 7.302668, states[40]= 0.004733
Saving checkpoint... 
Iteration: 1130186884, states[0] = -94.822864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1143657820, states[0] = -91.264747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1157291073, states[0] = -94.980438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170602163, states[0] = -25.292802, states[40]= 0.000648
Saving checkpoint... 
Iteration: 1182683591, states[0] = -94.814246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196314721, states[0] = -94.998446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1209944033, states[0] = -95.048435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223609239, states[0] = -32.364088, states[40]= 0.000334
Saving checkpoint... 
Iteration: 1237229642, states[0] = -94.907018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250827427, states[0] = -95.006482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1264465265, states[0] = -95.052212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278125906, states[0] = -49.692136, states[40]= 0.000027
Saving checkpoint... 
Iteration: 1291725474, states[0] = -94.900135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1305359541, states[0] = -95.022900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1318320916, states[0] = -95.002427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1331898102, states[0] = -95.037005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345523126, states[0] = 19.536346, states[40]= 0.007436
Saving checkpoint... 
Iteration: 1359150863, states[0] = -81.633197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1371532259, states[0] = 17.015516, states[40]= 0.005582
Saving checkpoint... 
Iteration: 1385138927, states[0] = -64.363145, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1398396943, states[0] = -95.036606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412037262, states[0] = 15.342702, states[40]= 0.005206
Saving checkpoint... 
Iteration: 1425422136, states[0] = -95.043482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1439071884, states[0] = 0.530007, states[40]= 0.004260
Saving checkpoint... 
Iteration: 1452701660, states[0] = -94.855365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1466305256, states[0] = -94.991556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1479929186, states[0] = -95.045102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493152102, states[0] = -83.696461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1506010590, states[0] = 22.750121, states[40]= 0.046027
Saving checkpoint... 
Iteration: 1519505559, states[0] = 26.944457, states[40]= 0.121684
Saving checkpoint... 
Iteration: 1533059966, states[0] = 0.733027, states[40]= 0.004813
Saving checkpoint... 
Iteration: 1546602086, states[0] = -44.306430, states[40]= 0.000066
Saving checkpoint... 
Iteration: 1558871413, states[0] = -9.496956, states[40]= 0.002737
Saving checkpoint... 
Iteration: 1572425506, states[0] = -76.291922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1586003422, states[0] = -95.240239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1599528874, states[0] = -95.283036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1612944176, states[0] = -94.863155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1626246412, states[0] = -95.307160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1639639780, states[0] = -94.214568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1653163852, states[0] = -95.153890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1666740612, states[0] = -95.301425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1680269974, states[0] = -95.332010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1693173601, states[0] = -95.335220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1706694081, states[0] = -95.350833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1720246349, states[0] = 8.303717, states[40]= 0.005553
Saving checkpoint... 
Iteration: 1732862284, states[0] = -1.707052, states[40]= 0.004452
Saving checkpoint... 
Iteration: 1745951119, states[0] = -95.313782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1759513145, states[0] = 21.659378, states[40]= 0.027097
Saving checkpoint... 
Iteration: 1773033705, states[0] = 14.583933, states[40]= 0.006355
Saving checkpoint... 
Iteration: 1786560297, states[0] = -0.231509, states[40]= 0.004694
Saving checkpoint... 
Iteration: 1799926246, states[0] = -95.282805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1813468856, states[0] = -95.103651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1827043246, states[0] = 12.656612, states[40]= 0.004962
Saving checkpoint... 
Iteration: 1840638411, states[0] = -65.624993, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1854171689, states[0] = -94.758519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1867711035, states[0] = -94.885109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1880586809, states[0] = -10.638354, states[40]= 0.002197
Saving checkpoint... 
Iteration: 1894142890, states[0] = -69.861538, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1907693746, states[0] = -94.841656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1919999007, states[0] = -95.058843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1933532579, states[0] = 16.894291, states[40]= 0.005550
Saving checkpoint... 
Iteration: 1947072054, states[0] = 0.403820, states[40]= 0.004246
Saving checkpoint... 
Iteration: 1960616566, states[0] = -39.841486, states[40]= 0.000123
Saving checkpoint... 
Iteration: 1974136488, states[0] = -61.507305, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1987494746, states[0] = -95.056197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2000870456, states[0] = -95.027146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2013850018, states[0] = -95.018171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2027360745, states[0] = -95.022991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2040872888, states[0] = -95.027902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2054416634, states[0] = -95.041680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2067305329, states[0] = -94.991181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2080888178, states[0] = -95.033306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2094400886, states[0] = -95.037284, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.932289
 - CaMKt in component CaMK (millimolar): 0.006888
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.593347
 - nass in component intracellular_ions (millimolar): 6.593407
 - ki in component intracellular_ions (millimolar): 145.385060
 - kss in component intracellular_ions (millimolar): 145.385040
 - cansr in component intracellular_ions (millimolar): 1.306122
 - cajsr in component intracellular_ions (millimolar): 1.268585
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003607
 - hf in component INa (dimensionless): 0.880528
 - hs in component INa (dimensionless): 0.880523
 - j in component INa (dimensionless): 0.880494
 - hsp in component INa (dimensionless): 0.726824
 - jp in component INa (dimensionless): 0.880475
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.711699
 - hLp in component INaL (dimensionless): 0.455846
 - a in component Ito (dimensionless): 0.000622
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.626377
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.702540
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.940027
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999901
 - jca in component ICaL (dimensionless): 0.999980
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001570
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.314628
 - xs1 in component IKs (dimensionless): 0.232979
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997329
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
06:03:57 (10048): called boinc_finish(0)

</stderr_txt>
]]>


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