𝕏

Task 55707372

Name HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_MID_1000-conf_487_2
Workunit 26232058
Created 1 Jul 2024, 16:24:35 UTC
Sent 2 Jul 2024, 14:00:24 UTC
Report deadline 5 Jul 2024, 14:00:24 UTC
Received 3 Jul 2024, 15:58:05 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 238614
Run time 2 hours 2 min 24 sec
CPU time 2 hours 1 min 57 sec
Validate state Valid
Credit 44.06
Device peak FLOPS 3.71 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.75 MB
Peak swap size 3.69 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.14.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_MID_1000-conf_487.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_MID_1000-conf_487_2_r1192505478_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240628073719801540_ORdGradInc_k_25-Drouin_MID_1000-conf_487_2_r1192505478_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 113.925379
     * GNaL_b in INaL: 0.004453
     * Gto_b in Ito: 0.089078
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030101
     * GKs_b in IKs: 0.001934
     * GK1_b in IK1: 0.151875
     * Gncx_b in INaCa_i: 0.000977
     * Pnak_b in INaK: 69.552919
     * GKb_b in IKb: 0.003892
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.043927
     * celltype in environment: 2.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 10889011, states[0] = -94.292552, states[40]= 0.000001
Saving checkpoint... 
Iteration: 23625573, states[0] = 1.618696, states[40]= 0.001917
Saving checkpoint... 
Iteration: 35583063, states[0] = 18.450879, states[40]= 0.000064
Saving checkpoint... 
Iteration: 46722324, states[0] = -63.601046, states[40]= 0.000327
Saving checkpoint... 
Iteration: 58862636, states[0] = -94.360760, states[40]= 0.000001
Saving checkpoint... 
Iteration: 69704719, states[0] = -54.389492, states[40]= 0.001378
Saving checkpoint... 
Iteration: 81218423, states[0] = -67.958400, states[40]= 0.000206
Saving checkpoint... 
Iteration: 92415235, states[0] = -94.490363, states[40]= 0.000001
Saving checkpoint... 
Iteration: 103713926, states[0] = -65.565002, states[40]= 0.000308
Saving checkpoint... 
Iteration: 116723153, states[0] = -78.229262, states[40]= 0.000048
Saving checkpoint... 
Iteration: 128108954, states[0] = 3.267092, states[40]= 0.003975
Saving checkpoint... 
Iteration: 140211587, states[0] = -64.689679, states[40]= 0.000363
Saving checkpoint... 
Iteration: 153364510, states[0] = -94.429674, states[40]= 0.000001
Saving checkpoint... 
Iteration: 166370638, states[0] = -94.442418, states[40]= 0.000001
Saving checkpoint... 
Iteration: 177187767, states[0] = -46.308311, states[40]= 0.004177
Saving checkpoint... 
Iteration: 190480377, states[0] = -94.553690, states[40]= 0.000001
Saving checkpoint... 
Iteration: 201424299, states[0] = -94.515908, states[40]= 0.000001
Saving checkpoint... 
Iteration: 213095125, states[0] = 10.214837, states[40]= 0.001278
Saving checkpoint... 
Iteration: 226627308, states[0] = -9.678915, states[40]= 0.006120
Saving checkpoint... 
Iteration: 239882381, states[0] = -94.458642, states[40]= 0.000001
Saving checkpoint... 
Iteration: 250552228, states[0] = 28.293715, states[40]= 0.000003
Saving checkpoint... 
Iteration: 261651260, states[0] = -25.938960, states[40]= 0.018780
Saving checkpoint... 
Iteration: 272192838, states[0] = -50.070530, states[40]= 0.002707
Saving checkpoint... 
Iteration: 283408786, states[0] = -94.491405, states[40]= 0.000001
Saving checkpoint... 
Iteration: 294583424, states[0] = 15.708923, states[40]= 0.000338
Saving checkpoint... 
Iteration: 304596046, states[0] = 9.754169, states[40]= 0.001408
Saving checkpoint... 
Iteration: 315602860, states[0] = 6.299959, states[40]= 0.002697
Saving checkpoint... 
Iteration: 325798688, states[0] = -94.185849, states[40]= 0.000001
Saving checkpoint... 
Iteration: 336290792, states[0] = -94.139888, states[40]= 0.000001
Saving checkpoint... 
Iteration: 346866650, states[0] = -94.417717, states[40]= 0.000001
Saving checkpoint... 
Iteration: 356785057, states[0] = -94.101714, states[40]= 0.000001
Saving checkpoint... 
Iteration: 366112596, states[0] = 0.818894, states[40]= 0.005352
Saving checkpoint... 
Iteration: 376067106, states[0] = 22.723074, states[40]= 0.000036
Saving checkpoint... 
Iteration: 387166474, states[0] = -33.531682, states[40]= 0.014305
Saving checkpoint... 
Iteration: 397389627, states[0] = -94.453206, states[40]= 0.000001
Saving checkpoint... 
Iteration: 407791944, states[0] = -94.138822, states[40]= 0.000001
Saving checkpoint... 
Iteration: 417825974, states[0] = -94.296745, states[40]= 0.000001
Saving checkpoint... 
Iteration: 428010664, states[0] = 31.422312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 438609818, states[0] = 2.480447, states[40]= 0.004553
Saving checkpoint... 
Iteration: 449364887, states[0] = -94.402715, states[40]= 0.000001
Saving checkpoint... 
Iteration: 459504891, states[0] = 25.518254, states[40]= 0.000001
Saving checkpoint... 
Iteration: 470367154, states[0] = -94.405166, states[40]= 0.000001
Saving checkpoint... 
Iteration: 480471495, states[0] = -94.519335, states[40]= 0.000001
Saving checkpoint... 
Iteration: 490824295, states[0] = -94.282494, states[40]= 0.000001
Saving checkpoint... 
Iteration: 500585970, states[0] = 14.552800, states[40]= 0.000456
Saving checkpoint... 
Iteration: 510719261, states[0] = -74.461787, states[40]= 0.000086
Saving checkpoint... 
Iteration: 520922017, states[0] = -94.479712, states[40]= 0.000001
Saving checkpoint... 
Iteration: 531137857, states[0] = -17.792566, states[40]= 0.007061
Saving checkpoint... 
Iteration: 541293395, states[0] = -94.132482, states[40]= 0.000001
Saving checkpoint... 
Iteration: 551022202, states[0] = 34.534333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 561248896, states[0] = -93.760691, states[40]= 0.000001
Saving checkpoint... 
Iteration: 571879581, states[0] = -94.417692, states[40]= 0.000001
Saving checkpoint... 
Iteration: 582217128, states[0] = -71.612793, states[40]= 0.000131
Saving checkpoint... 
Iteration: 592197676, states[0] = -53.645432, states[40]= 0.001725
Saving checkpoint... 
Iteration: 602407569, states[0] = -94.454996, states[40]= 0.000001
Saving checkpoint... 
Iteration: 612372211, states[0] = -94.399618, states[40]= 0.000001
Saving checkpoint... 
Iteration: 622426299, states[0] = -94.472600, states[40]= 0.000001
Saving checkpoint... 
Iteration: 632772769, states[0] = -93.983107, states[40]= 0.000001
Saving checkpoint... 
Iteration: 642865545, states[0] = -94.382746, states[40]= 0.000001
Saving checkpoint... 
Iteration: 653094573, states[0] = 10.494043, states[40]= 0.001191
Saving checkpoint... 
Iteration: 663199087, states[0] = -54.708780, states[40]= 0.001500
Saving checkpoint... 
Iteration: 673867087, states[0] = -94.382569, states[40]= 0.000001
Saving checkpoint... 
Iteration: 684222346, states[0] = -79.189680, states[40]= 0.000043
Saving checkpoint... 
Iteration: 694477829, states[0] = -94.498791, states[40]= 0.000001
Saving checkpoint... 
Iteration: 705000696, states[0] = 41.249175, states[40]= 0.376825
Saving checkpoint... 
Iteration: 715343547, states[0] = -94.320586, states[40]= 0.000001
Saving checkpoint... 
Iteration: 725424843, states[0] = -94.459920, states[40]= 0.000001
Saving checkpoint... 
Iteration: 735362023, states[0] = -94.364955, states[40]= 0.000001
Saving checkpoint... 
Iteration: 745626345, states[0] = -8.865769, states[40]= 0.006232
Saving checkpoint... 
Iteration: 755002277, states[0] = 22.813777, states[40]= 2.640691
Saving checkpoint... 
Iteration: 765437603, states[0] = -94.466659, states[40]= 0.000001
Saving checkpoint... 
Iteration: 775733005, states[0] = -92.206072, states[40]= 0.000003
Saving checkpoint... 
Iteration: 785953296, states[0] = -94.475638, states[40]= 0.000001
Saving checkpoint... 
Iteration: 796186607, states[0] = -45.617108, states[40]= 0.004500
Saving checkpoint... 
Iteration: 806371156, states[0] = -94.376215, states[40]= 0.000001
Saving checkpoint... 
Iteration: 816385590, states[0] = -94.400815, states[40]= 0.000001
Saving checkpoint... 
Iteration: 826837233, states[0] = -94.289460, states[40]= 0.000001
Saving checkpoint... 
Iteration: 837302771, states[0] = -94.150387, states[40]= 0.000001
Saving checkpoint... 
Iteration: 847888632, states[0] = -94.402198, states[40]= 0.000001
Saving checkpoint... 
Iteration: 858165227, states[0] = -32.859005, states[40]= 0.014980
Saving checkpoint... 
Iteration: 868297731, states[0] = -94.120459, states[40]= 0.000001
Saving checkpoint... 
Iteration: 878322289, states[0] = -94.232200, states[40]= 0.000001
Saving checkpoint... 
Iteration: 888492762, states[0] = -94.483548, states[40]= 0.000001
Saving checkpoint... 
Iteration: 898824128, states[0] = -94.236845, states[40]= 0.000001
Saving checkpoint... 
Iteration: 909709097, states[0] = -62.965945, states[40]= 0.000471
Saving checkpoint... 
Iteration: 920326536, states[0] = -94.243256, states[40]= 0.000001
Saving checkpoint... 
Iteration: 931126160, states[0] = -8.688026, states[40]= 0.006233
Saving checkpoint... 
Iteration: 942516032, states[0] = 33.818987, states[40]= -0.000000
Saving checkpoint... 
Iteration: 953255109, states[0] = -93.788419, states[40]= 0.000001
Saving checkpoint... 
Iteration: 964251907, states[0] = -93.752295, states[40]= 0.000001
Saving checkpoint... 
Iteration: 975553113, states[0] = 28.022397, states[40]= 0.000003
Saving checkpoint... 
Iteration: 986276132, states[0] = -93.969456, states[40]= 0.000001
Saving checkpoint... 
Iteration: 997213306, states[0] = -67.103137, states[40]= 0.000255
Saving checkpoint... 
Iteration: 1007850373, states[0] = -94.306883, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1018591183, states[0] = 12.142115, states[40]= 0.000813
Saving checkpoint... 
Iteration: 1029307578, states[0] = -94.152577, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1039843871, states[0] = -94.285702, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1050360336, states[0] = -94.326478, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1065036623, states[0] = 32.789181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1077323533, states[0] = -94.214736, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1087701171, states[0] = -56.292126, states[40]= 0.001208
Saving checkpoint... 
Iteration: 1103366835, states[0] = -94.334774, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1114329856, states[0] = -94.233506, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1124622730, states[0] = -6.013164, states[40]= 0.006594
Saving checkpoint... 
Iteration: 1134648381, states[0] = -24.323546, states[40]= 0.016772
Saving checkpoint... 
Iteration: 1145333484, states[0] = -94.242313, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1155955916, states[0] = -94.436807, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1166445137, states[0] = -94.428477, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1179783885, states[0] = -94.002695, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1190196270, states[0] = -52.570045, states[40]= 0.001964
Saving checkpoint... 
Iteration: 1201610807, states[0] = 1.974374, states[40]= 0.004678
Saving checkpoint... 
Iteration: 1212713906, states[0] = -67.725818, states[40]= 0.000231
Saving checkpoint... 
Iteration: 1223301684, states[0] = -94.102072, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1233956103, states[0] = -94.428292, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1244968935, states[0] = -94.434287, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1255604111, states[0] = 5.708684, states[40]= 0.002873
Saving checkpoint... 
Iteration: 1266274452, states[0] = -93.925527, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1276859953, states[0] = -94.300648, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1287238960, states[0] = -93.368975, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1297163095, states[0] = -31.752577, states[40]= 0.016094
Saving checkpoint... 
Iteration: 1307884070, states[0] = -94.344234, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1318836721, states[0] = -94.233495, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1329567217, states[0] = 22.723827, states[40]= 0.000034
Saving checkpoint... 
Iteration: 1340567721, states[0] = 22.519337, states[40]= 0.000037
Saving checkpoint... 
Iteration: 1351685556, states[0] = -44.871413, states[40]= 0.004848
Saving checkpoint... 
Iteration: 1362497252, states[0] = -94.433162, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1372717208, states[0] = -71.567323, states[40]= 0.000130
Saving checkpoint... 
Iteration: 1383472692, states[0] = -94.421007, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1394264225, states[0] = -93.826691, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1405198524, states[0] = -54.238648, states[40]= 0.001581
Saving checkpoint... 
Iteration: 1416646306, states[0] = -23.122647, states[40]= 0.014752
Saving checkpoint... 
Iteration: 1427680076, states[0] = -41.261130, states[40]= 0.007054
Saving checkpoint... 
Iteration: 1439396003, states[0] = -94.348046, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1450427184, states[0] = -94.382659, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1461363787, states[0] = -94.288910, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1471670114, states[0] = -35.407494, states[40]= 0.012135
Saving checkpoint... 
Iteration: 1482561177, states[0] = 25.108737, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1493568318, states[0] = 22.284086, states[40]= 0.000040
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.294902
 - CaMKt in component CaMK (millimolar): 0.053099
 - cass in component intracellular_ions (millimolar): 0.000105
 - nai in component intracellular_ions (millimolar): 8.603287
 - nass in component intracellular_ions (millimolar): 8.603490
 - ki in component intracellular_ions (millimolar): 142.220428
 - kss in component intracellular_ions (millimolar): 142.220389
 - cansr in component intracellular_ions (millimolar): 2.828685
 - cajsr in component intracellular_ions (millimolar): 2.780635
 - cai in component intracellular_ions (millimolar): 0.000110
 - m in component INa (dimensionless): 0.003847
 - hf in component INa (dimensionless): 0.869064
 - hs in component INa (dimensionless): 0.869050
 - j in component INa (dimensionless): 0.868954
 - hsp in component INa (dimensionless): 0.705490
 - jp in component INa (dimensionless): 0.868878
 - mL in component INaL (dimensionless): 0.000056
 - hL in component INaL (dimensionless): 0.669779
 - hLp in component INaL (dimensionless): 0.380006
 - a in component Ito (dimensionless): 0.000649
 - iF in component Ito (dimensionless): 0.999855
 - iS in component Ito (dimensionless): 0.547063
 - ap in component Ito (dimensionless): 0.000331
 - iFp in component Ito (dimensionless): 0.999855
 - iSp in component Ito (dimensionless): 0.607823
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.865157
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999499
 - jca in component ICaL (dimensionless): 0.999928
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.006066
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.450266
 - xs1 in component IKs (dimensionless): 0.342609
 - xs2 in component IKs (dimensionless): 0.000094
 - xk1 in component IK1 (dimensionless): 0.997493
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
17:30:19 (100838): called boinc_finish(0)

</stderr_txt>
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