𝕏

Task 55705650

Name HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_EPI_4000-conf_598_0
Workunit 26453633
Created 1 Jul 2024, 16:18:16 UTC
Sent 2 Jul 2024, 13:50:15 UTC
Report deadline 5 Jul 2024, 13:50:15 UTC
Received 3 Jul 2024, 9:11:13 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 233458
Run time 1 hours 54 min 21 sec
CPU time 1 hours 53 min 43 sec
Validate state Valid
Credit 43.90
Device peak FLOPS 3.16 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.59 MB
Peak swap size 6.21 MB
Peak disk usage 0.02 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_EPI_4000-conf_598.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_EPI_4000-conf_598_0_r1634167360_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701173204476709_ORdGradInc_k_26-Drouin_EPI_4000-conf_598_0_r1634167360_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 101.605236
     * GNaL_b in INaL: 0.005432
     * Gto_b in Ito: 0.087929
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031957
     * GKs_b in IKs: 0.001889
     * GK1_b in IK1: 0.167032
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 70.413793
     * GKb_b in IKb: 0.003836
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029592
     * celltype in environment: 1.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 5782007, states[0] = -94.412167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 14413119, states[0] = -94.302089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23056271, states[0] = -94.310069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 31614894, states[0] = -94.275267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40153879, states[0] = -46.963665, states[40]= 0.000100
Saving checkpoint... 
Iteration: 48746713, states[0] = -94.291218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57316280, states[0] = -94.270286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65749713, states[0] = -94.261584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 74193379, states[0] = -93.315346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 82769741, states[0] = -94.297542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 88203814, states[0] = -93.589931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96518583, states[0] = -94.289672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 105279765, states[0] = -94.282543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 114158886, states[0] = -55.637428, states[40]= 0.000052
Saving checkpoint... 
Iteration: 122935189, states[0] = -94.298335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 131640608, states[0] = -94.276399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 140328534, states[0] = -94.145879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 149008520, states[0] = -94.297191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 157476437, states[0] = -94.281743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 166354141, states[0] = -94.189788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 171686753, states[0] = -94.277387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180270338, states[0] = -93.985146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 186387338, states[0] = -94.229746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194643538, states[0] = -94.309280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 203232827, states[0] = -94.289674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 211610317, states[0] = -94.279293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 220092273, states[0] = 8.313250, states[40]= 0.000053
Saving checkpoint... 
Iteration: 228640997, states[0] = -94.309174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 237060574, states[0] = -94.295988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245610548, states[0] = -94.279100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 251035297, states[0] = -94.296910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259530698, states[0] = -94.280798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262468452, states[0] = -94.281676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270969202, states[0] = -94.299509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279536856, states[0] = -94.280437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 288107048, states[0] = -1.019414, states[40]= 0.000214
Saving checkpoint... 
Iteration: 296574696, states[0] = -94.304663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 305032673, states[0] = -94.296433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 313531988, states[0] = -94.280159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321981492, states[0] = -94.271669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 330668622, states[0] = -94.308518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339282738, states[0] = -94.286779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 347799537, states[0] = -94.274232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 356356721, states[0] = -94.192400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 364795610, states[0] = -94.305595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 373308166, states[0] = -94.285546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 381921652, states[0] = -94.271800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 389963048, states[0] = -94.271079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398067999, states[0] = 19.503864, states[40]= 0.000002
Saving checkpoint... 
Iteration: 406529480, states[0] = -94.296956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415025584, states[0] = -94.295347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 423455262, states[0] = -94.280693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 431986075, states[0] = -94.270208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 440580746, states[0] = -94.303430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449108040, states[0] = -94.291580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457672284, states[0] = -94.275233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466257281, states[0] = -93.927586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474677999, states[0] = -94.306717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 483182577, states[0] = -94.288352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491813059, states[0] = -94.272155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 500249668, states[0] = -93.890977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 508854897, states[0] = -94.301443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517457042, states[0] = -94.279441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 526025715, states[0] = 25.316211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534526029, states[0] = -94.294659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 543021840, states[0] = -94.293867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551471735, states[0] = -94.278628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 560172214, states[0] = -73.101595, states[40]= 0.000005
Saving checkpoint... 
Iteration: 565204681, states[0] = -94.286524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 573732484, states[0] = -94.272570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582328563, states[0] = -94.143165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 590898284, states[0] = -94.298563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599431818, states[0] = -94.279066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 608040996, states[0] = 25.878669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 616687651, states[0] = -94.304887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624471419, states[0] = -94.278285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 632921856, states[0] = -94.297006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641413354, states[0] = -94.279031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649947340, states[0] = -94.267981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 658500463, states[0] = -94.287178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 667207099, states[0] = -94.285133, states[40]= 0.000000
Saving checkpoint... 
Iteration: 675781599, states[0] = -94.270358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 684350820, states[0] = -94.179690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 692856849, states[0] = -94.299020, states[40]= 0.000000
Saving checkpoint... 
Iteration: 701530974, states[0] = -94.275240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 710038437, states[0] = 26.027621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 718571199, states[0] = -94.298954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727074234, states[0] = -94.289367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735589954, states[0] = -94.273435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 744142298, states[0] = -36.737819, states[40]= 0.000366
Saving checkpoint... 
Iteration: 752723056, states[0] = -94.302716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 761257595, states[0] = -94.282209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 769714904, states[0] = -94.270396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 778252279, states[0] = -93.900107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 786870634, states[0] = -94.297237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795361909, states[0] = -94.278522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803940057, states[0] = -94.266116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812578807, states[0] = -94.298506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821246364, states[0] = -94.281816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829997570, states[0] = -94.264951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 838740357, states[0] = -94.301242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 847485542, states[0] = -94.274491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 856333899, states[0] = -94.149621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 864265103, states[0] = -93.956282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 872923639, states[0] = -94.293864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 881465518, states[0] = -94.274566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 890217039, states[0] = -93.691088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898966711, states[0] = -94.291664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 907599972, states[0] = -94.271009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 916114246, states[0] = -7.015451, states[40]= 0.000295
Saving checkpoint... 
Iteration: 924805966, states[0] = -94.298068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 933728033, states[0] = -94.268042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 942499522, states[0] = -94.283292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 951161031, states[0] = -94.283154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 959879375, states[0] = -94.265058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 968580637, states[0] = -94.296681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977351751, states[0] = -94.276493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 982771971, states[0] = -94.298506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 991386984, states[0] = -94.275291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 999827407, states[0] = -94.265408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1008259865, states[0] = -93.932052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016935310, states[0] = -94.291517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025474056, states[0] = -94.272502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033873494, states[0] = -94.264206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1042291219, states[0] = -94.046511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1050625157, states[0] = -94.298423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1059233744, states[0] = -94.279195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067770114, states[0] = -94.265542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1076326926, states[0] = -94.133602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1084962381, states[0] = -94.289472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1091126380, states[0] = -94.282664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1099733088, states[0] = -94.265818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1108162387, states[0] = -60.242789, states[40]= 0.000028
Saving checkpoint... 
Iteration: 1116686004, states[0] = -94.298507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1125270859, states[0] = -94.277114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1133673215, states[0] = -94.266560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142130866, states[0] = -24.276870, states[40]= 0.000385
Saving checkpoint... 
Iteration: 1150657507, states[0] = -94.297958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1159351211, states[0] = -94.274182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1168053042, states[0] = 24.023708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1176635389, states[0] = -94.297164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1185306135, states[0] = -94.275221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1194010485, states[0] = 20.750934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1202810625, states[0] = -94.294340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1211782637, states[0] = -94.263469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220510950, states[0] = -94.282641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1229150190, states[0] = -94.279999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1237975359, states[0] = -94.260035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1246747117, states[0] = -94.295854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1255399174, states[0] = -94.271563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1263904136, states[0] = -94.260769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1272790827, states[0] = -94.294166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1281544813, states[0] = -94.267478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290250335, states[0] = -93.883922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298911855, states[0] = -94.288927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1307407649, states[0] = -94.270665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1316195184, states[0] = -93.456274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1324923281, states[0] = -94.288104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1332791279, states[0] = -94.293389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1341450093, states[0] = -94.269081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350183356, states[0] = -90.215549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1359051196, states[0] = -94.282220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367760886, states[0] = -94.261870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1376511566, states[0] = -94.280796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385226771, states[0] = -94.275264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1393910502, states[0] = -94.259009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1402522010, states[0] = -94.282765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411376298, states[0] = -94.270222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1420017573, states[0] = 23.521475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1428713017, states[0] = -94.294259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437550519, states[0] = -94.265352, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1446255019, states[0] = -93.904353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454792265, states[0] = -94.291798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1463316926, states[0] = -94.271331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1472150274, states[0] = -46.003292, states[40]= 0.000163
Saving checkpoint... 
Iteration: 1481001459, states[0] = -94.282739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489582773, states[0] = -94.263942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1498083572, states[0] = 12.809147, states[40]= 0.000019
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.132301
 - CaMKt in component CaMK (millimolar): 0.002347
 - cass in component intracellular_ions (millimolar): 0.000101
 - nai in component intracellular_ions (millimolar): 7.167317
 - nass in component intracellular_ions (millimolar): 7.167456
 - ki in component intracellular_ions (millimolar): 144.499481
 - kss in component intracellular_ions (millimolar): 144.499466
 - cansr in component intracellular_ions (millimolar): 2.430007
 - cajsr in component intracellular_ions (millimolar): 2.430524
 - cai in component intracellular_ions (millimolar): 0.000106
 - m in component INa (dimensionless): 0.003911
 - hf in component INa (dimensionless): 0.865992
 - hs in component INa (dimensionless): 0.865993
 - j in component INa (dimensionless): 0.865996
 - hsp in component INa (dimensionless): 0.699992
 - jp in component INa (dimensionless): 0.865998
 - mL in component INaL (dimensionless): 0.000057
 - hL in component INaL (dimensionless): 0.708438
 - hLp in component INaL (dimensionless): 0.514530
 - a in component Ito (dimensionless): 0.000657
 - iF in component Ito (dimensionless): 0.999851
 - iS in component Ito (dimensionless): 0.999851
 - ap in component Ito (dimensionless): 0.000335
 - iFp in component Ito (dimensionless): 0.999851
 - iSp in component Ito (dimensionless): 0.999851
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.996787
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005392
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.006585
 - xs1 in component IKs (dimensionless): 0.039520
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997532
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
11:09:01 (7824): called boinc_finish(0)

</stderr_txt>
]]>


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